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  1. Article ; Online: Breaking away from an endemic state of multidrug-resistant

    Iwasaki, Sumio / Sato, Rikako / Kagami, Keisuke / Akizawa, Kouji / Hayasaka, Kasumi / Fukumoto, Tatsuya / Taki, Keisuke / Niinuma, Yusuke / Yamada, Takehiro / Oyamada, Reiko / Watanabe, Tsubasa / Nakakubo, Sho / Watanabe, Chiaki / Teshima, Takanori / Ishiguro, Nobuhisa

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2023  Volume 3, Issue 1, Page(s) e209

    Abstract: The detection rate of multidrug- ... ...

    Abstract The detection rate of multidrug-resistant
    Language English
    Publishing date 2023-11-15
    Publishing country England
    Document type Journal Article
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2023.484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults: Study Protocol for a Randomized Controlled Trial.

    Shinada, Takamitsu / Takano, Yuji / Kokubun, Keisuke / Iki, Hikari / Taki, Yasuyuki

    Methods and protocols

    2021  Volume 4, Issue 4

    Abstract: Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the ... ...

    Abstract Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the effects of natural reduced water on diabetes, which is one of the known risks for dementia. Animal studies of natural reduced water have revealed anti-obesity and anti-anxiety effects. However, the effects of natural reduced water on cognitive function, body composition, and psychological function in humans are unknown. Therefore, we investigated the relationship between these items in elderly people who continuously consume natural reduced water. In this study, we recruited participants aged between 65 and 74 years. The participants were randomly and blindly assigned to a natural reduced water (Hita Tenryosui water) group or a control (tap water) group and drank 1 L of water daily for 6 months. Cognitive function, body composition, and psychological function were measured before and after the 6-month intervention period.
    Language English
    Publishing date 2021-10-14
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2409-9279
    ISSN (online) 2409-9279
    DOI 10.3390/mps4040073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of the Intake of Brown Rice for Six Months on the Cognitive Function in Healthy Elderly Persons: A Study Protocol for a Pilot, Non-Randomized Controlled Trial.

    Takano, Yuji / Kokubun, Keisuke / Saika, Keiji / Nishiyama, Naoki / Taki, Yasuyuki

    Methods and protocols

    2021  Volume 4, Issue 4

    Abstract: The nutritional components of brown rice have been reported to be effective against diabetes mellitus. Recent animal studies have suggested that it is also effective in maintaining cognitive function. Therefore, in this study, we examined the effect of a ...

    Abstract The nutritional components of brown rice have been reported to be effective against diabetes mellitus. Recent animal studies have suggested that it is also effective in maintaining cognitive function. Therefore, in this study, we examined the effect of a brown rice diet on cognitive function in individuals aged over 60 years. The study participants were recruited from a pool of individuals aged ≥60 years who were using elderly care facilities. The participants were provided with four servings of brown or white rice per week for 6 months, and their cognitive function was measured before and after the intervention period. Prior to the intervention, participants tasted the white and brown rice to determine which type they would like to be offered over the 6-month period. Since rice is the staple food of the participants in this study, they were allowed to decide whether they wanted to eat white or brown rice.
    Language English
    Publishing date 2021-10-28
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2409-9279
    ISSN (online) 2409-9279
    DOI 10.3390/mps4040078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Breaking away from an endemic state of multidrug-resistant Pseudomonas aeruginosa by daily sink disinfection

    Sumio Iwasaki / Rikako Sato / Keisuke Kagami / Kouji Akizawa / Kasumi Hayasaka / Tatsuya Fukumoto / Keisuke Taki / Yusuke Niinuma / Takehiro Yamada / Reiko Oyamada / Tsubasa Watanabe / Sho Nakakubo / Chiaki Watanabe / Takanori Teshima / Nobuhisa Ishiguro

    Antimicrobial Stewardship & Healthcare Epidemiology, Vol

    2023  Volume 3

    Abstract: The detection rate of multidrug-resistant Pseudomonas aeruginosa in patients admitted to 2 wards and the intensive care unit decreased from 20.3% (129 of 636 isolates) to 4.2% (37 of 889 isolates) after the start of disinfection of hand washing sinks ... ...

    Abstract The detection rate of multidrug-resistant Pseudomonas aeruginosa in patients admitted to 2 wards and the intensive care unit decreased from 20.3% (129 of 636 isolates) to 4.2% (37 of 889 isolates) after the start of disinfection of hand washing sinks using alkyl diaminoethylglycine hydrochloride.
    Keywords Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Correlation between antibiotic use and resistance of gram-negative bacteria at a university hospital in Japan from 2013 to 2021: a study using the Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system.

    Kagami, Keisuke / Ishiguro, Nobuhisa / Iwasaki, Sumio / Taki, Keisuke / Fukumoto, Tatsuya / Hayasaka, Kasumi / Oyamada, Reiko / Watanabe, Tsubasa / Nakakubo, Sho / Niinuma, Yusuke / Sugawara, Mitsuru / Takekuma, Yoh

    European journal of hospital pharmacy : science and practice

    2023  

    Abstract: Objectives: The Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system aggregates information related to antimicrobial resistance (AMR) measures. We aimed to investigate the correlation between antibiotic use and AMR at ...

    Abstract Objectives: The Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) system aggregates information related to antimicrobial resistance (AMR) measures. We aimed to investigate the correlation between antibiotic use and AMR at a university hospital from 2013 to 2021 in a time series analysis using the J-SIPHE system. We also studied this correlation in each ward (inter-ward analysis).
    Methods: Data on antibiotic use and resistance rates were collected from the J-SIPHE system, except for the resistance rate in each ward, which was calculated from the source data prepared for this system.
    Results: Piperacillin/tazobactam use was positively correlated with piperacillin/tazobactam resistance in
    Conclusions: This is the first study to investigate the correlation between antibiotic use and AMR at a single hospital in time series and inter-ward analyses using the J-SIPHE system and data prepared for this system, suggesting that this system may be useful for promoting AMR measures.
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2650179-X
    ISSN 2047-9964 ; 2047-9956
    ISSN (online) 2047-9964
    ISSN 2047-9956
    DOI 10.1136/ejhpharm-2023-003797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of the Intake of Brown Rice for Six Months on the Cognitive Function in Healthy Elderly Persons

    Yuji Takano / Keisuke Kokubun / Keiji Saika / Naoki Nishiyama / Yasuyuki Taki

    Methods and Protocols, Vol 4, Iss 78, p

    A Study Protocol for a Pilot, Non-Randomized Controlled Trial

    2021  Volume 78

    Abstract: The nutritional components of brown rice have been reported to be effective against diabetes mellitus. Recent animal studies have suggested that it is also effective in maintaining cognitive function. Therefore, in this study, we examined the effect of a ...

    Abstract The nutritional components of brown rice have been reported to be effective against diabetes mellitus. Recent animal studies have suggested that it is also effective in maintaining cognitive function. Therefore, in this study, we examined the effect of a brown rice diet on cognitive function in individuals aged over 60 years. The study participants were recruited from a pool of individuals aged ≥60 years who were using elderly care facilities. The participants were provided with four servings of brown or white rice per week for 6 months, and their cognitive function was measured before and after the intervention period. Prior to the intervention, participants tasted the white and brown rice to determine which type they would like to be offered over the 6-month period. Since rice is the staple food of the participants in this study, they were allowed to decide whether they wanted to eat white or brown rice.
    Keywords brown rice ; cognitive function ; elderly ; Japanese ; Biology (General) ; QH301-705.5
    Subject code 150
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults

    Takamitsu Shinada / Yuji Takano / Keisuke Kokubun / Hikari Iki / Yasuyuki Taki

    Methods and Protocols, Vol 4, Iss 73, p

    Study Protocol for a Randomized Controlled Trial

    2021  Volume 73

    Abstract: Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the ... ...

    Abstract Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the effects of natural reduced water on diabetes, which is one of the known risks for dementia. Animal studies of natural reduced water have revealed anti-obesity and anti-anxiety effects. However, the effects of natural reduced water on cognitive function, body composition, and psychological function in humans are unknown. Therefore, we investigated the relationship between these items in elderly people who continuously consume natural reduced water. In this study, we recruited participants aged between 65 and 74 years. The participants were randomly and blindly assigned to a natural reduced water (Hita Tenryosui water) group or a control (tap water) group and drank 1 L of water daily for 6 months. Cognitive function, body composition, and psychological function were measured before and after the 6-month intervention period.
    Keywords natural reduced water ; diabetes ; cognitive function ; body composition ; psychological function ; Biology (General) ; QH301-705.5
    Subject code 500
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Staged treatment for ruptured wide-neck intracranial aneurysm with intentional partial coiling in the acute phase followed by definitive treatment.

    Yamazaki, Hiroki / Fujinaka, Toshiyuki / Ozaki, Tomohiko / Kidani, Tomoki / Nishimoto, Keisuke / Taki, Kowashi / Nishizawa, Naoki / Murakami, Keijiro / Kanemura, Yonehiro / Nakajima, Shin

    Surgical neurology international

    2022  Volume 13, Page(s) 322

    Abstract: Background: Evidence supports endovascular coiling for ruptured intracranial aneurysms (RIAs). However, in some cases, it is difficult to achieve complete occlusion by coiling, such as with wide-neck aneurysms. We report our experience with intentional ... ...

    Abstract Background: Evidence supports endovascular coiling for ruptured intracranial aneurysms (RIAs). However, in some cases, it is difficult to achieve complete occlusion by coiling, such as with wide-neck aneurysms. We report our experience with intentional staged RIA treatment using targeted endovascular coiling at the rupture point in the acute phase, followed by delayed stent-assisted coiling, flow diverter stenting, or surgical clipping.
    Methods: Consecutive patients with RIAs treated between April 2015 and June 2021 were retrospectively investigated. Clinical characteristics, treatment complications, and patient outcomes data were collected.
    Results: Among 108 RIAs treated in our hospital, 60 patients underwent initial coiling; 10 patients underwent staged treatment. The aneurysm locations were the anterior communicating artery (
    Conclusion: Intentional staged treatment with a short time interval for RIA was effective and feasible.
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Journal Article
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_529_2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Coil Embolization of Unruptured Cerebral Aneurysms Using Stents in Small Arteries Less Than 2 mm in Diameter.

    Ozaki, Tomohiko / Fujinaka, Toshiyuki / Kidani, Tomoki / Nishimoto, Keisuke / Yamazaki, Hiroki / Sawada, Haruna / Taki, Kowashi / Kanemura, Yonehiro / Nakajima, Shin

    Neurosurgery

    2022  Volume 90, Issue 5, Page(s) 538–546

    Abstract: Background: Data regarding the safety and effectiveness of stent placement in small vessels (<2 mm in diameter) for treating wide-necked cerebral aneurysms are limited.: Objective: To report our experience regarding coil embolization of unruptured ... ...

    Abstract Background: Data regarding the safety and effectiveness of stent placement in small vessels (<2 mm in diameter) for treating wide-necked cerebral aneurysms are limited.
    Objective: To report our experience regarding coil embolization of unruptured cerebral aneurysms using stents (specifically the Neuroform Atlas) in small arteries <2 mm in diameter.
    Methods: Patients with unruptured cerebral aneurysms treated with stent-assisted coil embolization between March 2017 and March 2021 in our hospital were included.
    Results: Of the 137 cerebral aneurysms included in this study, 49 required stent placement and 48 were treated using the Neuroform Atlas in the small vessels measuring <2 mm in diameter (small vessel group [SVG]). In the SVG, 43 aneurysms (87.8%) demonstrated complete occlusion. Regarding complications, 2 (4.1%) patients had in-stent thrombosis during procedures and 5 (10.2%) experienced symptomatic thromboembolic complications, but only 2 (4.1%) had worsening of the modified Rankin scale ≥1 at 90 days after embolization. Patients with middle cerebral artery aneurysms had a higher risk of thrombotic events (5/18 patients, 27.8%), such as symptomatic thromboembolic complications or intraprocedural in-stent thrombus than those with other aneurysms (1/31 patients, 3.2%), in the SVG (P = .0167).
    Conclusion: Stent-assisted coil embolization for unruptured cerebral aneurysms using stents, especially the Neuroform Atlas, in small arteries <2 mm in diameter is effective and feasible, but careful perioperative attention should be given to thrombotic events during the embolization of middle cerebral artery aneurysms.
    MeSH term(s) Arteries ; Blood Vessel Prosthesis ; Cerebral Angiography/methods ; Embolization, Therapeutic/adverse effects ; Embolization, Therapeutic/methods ; Humans ; Intracranial Aneurysm/surgery ; Intracranial Aneurysm/therapy ; Retrospective Studies ; Stents/adverse effects ; Thromboembolism/therapy ; Thrombosis ; Treatment Outcome
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000001876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tension pneumocephalus following cranioplasty with a titanium plate: a case report.

    Sawada, Haruna / Ozaki, Tomohiko / Nakajima, Shin / Kidani, Tomoki / Kanemura, Yonehiro / Nishimoto, Keisuke / Yamazaki, Hiroki / Taki, Kowashi / Fujinaka, Toshiyuki

    The Journal of international medical research

    2022  Volume 50, Issue 1, Page(s) 3000605221076032

    Abstract: Tension pneumocephalus (TP) can be a life-threatening postoperative complication, but there are limited data owing to its exceedingly low frequency. A 48-year-old man that suffered a head injury survived the acute phase and cranioplasty was performed ... ...

    Abstract Tension pneumocephalus (TP) can be a life-threatening postoperative complication, but there are limited data owing to its exceedingly low frequency. A 48-year-old man that suffered a head injury survived the acute phase and cranioplasty was performed using a titanium plate. Progressive deterioration of consciousness occurred the day after the cranioplasty. Computed tomography showed the presence of expanded air in the left epidural cavity and a midline shift to the right side. Emergency skin flap reopening was performed. Tension of the scalp decreased when the skin suture was cut and the wound reopened. Lucidity and improved right hemiparesis were obtained within a few hours after drain insertion. Pooled air in the left epidural cavity gradually dissipated postoperatively and the epidural drain was removed 2 days after insertion. The patient was discharged 27 days after cranioplasty, with a modified Rankin scale score of 2. The mechanism that caused TP was considered. Specifically, the skin flap acted as a one-way valve and trapped air. Then the trapped air expanded as the patient's body temperature warmed. TP should be considered a differential diagnosis after craniotomy. Emergency skin flap reopening and drain insertion may be an effective treatment for TP in the epidural space.
    MeSH term(s) Craniotomy/adverse effects ; Humans ; Male ; Middle Aged ; Pneumocephalus/diagnostic imaging ; Pneumocephalus/etiology ; Pneumocephalus/surgery ; Skull ; Surgical Flaps ; Titanium
    Chemical Substances Titanium (D1JT611TNE)
    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/03000605221076032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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