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Article ; Online: Steering Lu

Yu, Pengwei / Hu, Shuaifeng / Tian, Xinyue / Shen, Wangqiang / Yu, Pengyuan / Guo, Kun / Xie, Yunpeng / Bao, Lipiao / Lu, Xing

Nanoscale

2022 Volume 14, Issue 46, Page(s) 17290–17296

Abstract: ... to-compare cluster configuration and cage arrangement, namely Lu ...

Abstract	While the strong interaction between the internal unit and the fullerene cage inside metallofullerenes is widely acknowledged, how the cage transformation interacts with the cluster configuration remains elusive. For this purpose, we herein synthesized three metallofullerene molecules with an easy-to-compare cluster configuration and cage arrangement, namely Lu
Language	English
Publishing date	2022-12-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d2nr05049h
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Article: The Zhu-Lu formula: a machine learning-based intraocular lens power calculation formula for highly myopic eyes.

Guo, Dongling / He, Wenwen / Wei, Ling / Song, Yunxiao / Qi, Jiao / Yao, Yunqian / Chen, Xu / Huang, Jinhai / Lu, Yi / Zhu, Xiangjia

Eye and vision (London, England)

2023 Volume 10, Issue 1, Page(s) 26

Abstract: ... myopic patients from two other hospitals were used as external test dataset. The Zhu-Lu formula was ... Results: In the internal test dataset, the Zhu-Lu, RBF 3.0 and BUII ranked top three from low to high ... taking into account standard deviations (SDs) of prediction errors (PEs). The Zhu-Lu and RBF 3.0 showed ...

Abstract	Background: To develop a novel machine learning-based intraocular lens (IOL) power calculation formula for highly myopic eyes. Methods: A total of 1828 eyes (from 1828 highly myopic patients) undergoing cataract surgery in our hospital were used as the internal dataset, and 151 eyes from 151 highly myopic patients from two other hospitals were used as external test dataset. The Zhu-Lu formula was developed based on the eXtreme Gradient Boosting and the support vector regression algorithms. Its accuracy was compared in the internal and external test datasets with the Barrett Universal II (BUII), Emmetropia Verifying Optical (EVO) 2.0, Kane, Pearl-DGS and Radial Basis Function (RBF) 3.0 formulas. Results: In the internal test dataset, the Zhu-Lu, RBF 3.0 and BUII ranked top three from low to high taking into account standard deviations (SDs) of prediction errors (PEs). The Zhu-Lu and RBF 3.0 showed significantly lower median absolute errors (MedAEs) than the other formulas (all P < 0.05). In the external test dataset, the Zhu-Lu, Kane and EVO 2.0 ranked top three from low to high considering SDs of PEs. The Zhu-Lu formula showed a comparable MedAE with BUII and EVO 2.0 but significantly lower than Kane, Pearl-DGS and RBF 3.0 (all P < 0.05). The Zhu-Lu formula ranked first regarding the percentages of eyes within ± 0.50 D of the PE in both test datasets (internal: 80.61%; external: 72.85%). In the axial length subgroup analysis, the PE of the Zhu-Lu stayed stably close to zero in all subgroups. Conclusions: The novel IOL power calculation formula for highly myopic eyes demonstrated improved and stable predictive accuracy compared with other artificial intelligence-based formulas.
Language	English
Publishing date	2023-06-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2806610-8
ISSN	2326-0254
ISSN	2326-0254
DOI	10.1186/s40662-023-00342-5
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Article ; Online: Modified Hu-lu-ba-wan protects diabetic glomerular podocytes via promoting PKM2-mediated mitochondrial dynamic homeostasis.

Gong, Minmin / Guo, Yujin / Dong, Hui / Wu, Fan / He, Qiongyao / Gong, Jing / Lu, Fuer

Phytomedicine : international journal of phytotherapy and phytopharmacology

2023 Volume 123, Page(s) 155247

Abstract: ... induced apoptosis and improve renal injury in DKD. Modified Hu-lu-ba-wan (MHLBW) shows distinct clinical ...

Abstract	Background: Mitochondrial dysfunction is implicated in the progression of diabetic kidney disease (DKD). Damaged mitochondria produce excessive reactive oxygen species (ROS) that can cause apoptosis. Mitochondrial dynamics control the quality and function of mitochondria. Targeting mitochondrial dynamics may reduce ROS-induced apoptosis and improve renal injury in DKD. Modified Hu-lu-ba-wan (MHLBW) shows distinct clinical effects on DKD patients, which are related to its role in antioxidant stress modulation. However, the relevant mechanisms of MHLBW have not been clearly explored. Purpose: This study was aimed to evaluate the therapeutic effects of MHLBW on spontaneous DKD mice and clarify the potential mechanisms. Methods: The main components of MHLBW were identified by HPLC. Using db/db mice as DKD models, we evaluated the therapeutic effects of MHLBW on mice after an 8-week administration. We investigated the molecular mechanism of MHLBW in regulating mitochondrial dynamic homeostasis, podocyte apoptosis, and glomerular damage. After that, computational docking analysis and in vitro experiments were conducted for further mechanism verification. Results: Intragastric administration of MHLBW for 8 weeks in db/db mice significantly improved glucose metabolism, basement membrane thickening, mesangial expansion, glomerular fibrosis, and podocyte injury. MHLBW can reverse podocyte apoptosis via promoting mitochondrial dynamic homeostasis, which was related to regulating the PKM2/ PGC-1α/Opa1 pathway. Berberine (BBR), one of the components of MHLBW, exhibited preeminent affinity with PKM2 as reflected by computational docking analysis. In cultured podocytes, BBR can also prevent apoptosis by promoting PKM2-mediated mitochondrial dynamic homeostasis. Conclusion: Our study demonstrates that MHLBW can treat DKD by inhibiting glomerular damage and podocyte apoptosis through positive regulation of PKM2-mediated mitochondrial dynamic homeostasis. These results may provide a potential strategy against DKD.
MeSH term(s)	Humans ; Mice ; Animals ; Podocytes/metabolism ; Mitochondrial Dynamics ; Reactive Oxygen Species/metabolism ; Diabetic Nephropathies/metabolism ; Homeostasis ; Apoptosis ; Diabetes Mellitus
Chemical Substances	Reactive Oxygen Species
Language	English
Publishing date	2023-12-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2023.155247
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Article: [Hydrochemical Characteristics, Controlling Factors and Water Quality Evaluation of Shallow Groundwater in Tan-Lu Fault Zone （Anhui Section）].

Liu, Hai / Wei, Wei / Song, Yang / Xu, Jie / Guan, Zheng-Ting / Huang, Jian-Min / Zhao, Guo-Hong

Huan jing ke xue= Huanjing kexue

2024 Volume 45, Issue 5, Page(s) 2665–2677

Abstract: ... Lu fault zone (Anhui section), 86 groundwater samples were taken from the areas surrounding the Tan ... Lu fault zone (Anhui section), which included the Jianghuai Wavy Plain, the Yanjiang Hill Plain, and ... and to evaluate its quality. The results showed that the shallow groundwater in the Tan-Lu fault zone ...

Abstract	To study the hydrochemical characteristics, controlling factors, and groundwater quality of the Tan-Lu fault zone (Anhui section), 86 groundwater samples were taken from the areas surrounding the Tan-Lu fault zone (Anhui section), which included the Jianghuai Wavy Plain, the Yanjiang Hill Plain, and the Dabie Mountains in western Anhui. Descriptive statistics, Piper diagram, Gibbs diagram, ion ratio analysis, saturation index, chloride-alkalinity index, and entropy weight water quality index (EWQI) were used to comprehensively study the hydrochemical characteristics and controlling factors of groundwater and to evaluate its quality. The results showed that the shallow groundwater in the Tan-Lu fault zone (Anhui section) was weakly alkaline, with dominant anions and cations of HCO
Language	Chinese
Publishing date	2024-04-17
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	0250-3301
ISSN	0250-3301
DOI	10.13227/j.hjkx.202305144
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Article: In memory of Prof. Lu Shibi, MD.

Guo, Quanyi / Peng, Jiang / Wang, Aiyuan / Li, Gang / Qin, Ling

Journal of orthopaedic translation

2020 Volume 23, Page(s) A1

Language	English
Publishing date	2020-08-12
Publishing country	Singapore
Document type	Editorial
ZDB-ID	2747531-1
ISSN	2214-031X
ISSN	2214-031X
DOI	10.1016/j.jot.2020.06.007
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Article ; Online: Response to "The Effect of Neiguan Point (P6) Acupressure With Wristband on Postoperative Nausea, Vomiting, and Comfort Level: A Randomized Controlled Study" from Lu et al.

Lu, Hai / Han, Lisha / Hu, Jiahui / Guo, Yunping / Zhang, Chunhong

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

2019 Volume 34, Issue 4, Page(s) 676–677

MeSH term(s)	Acupressure ; Acupuncture Points ; Humans ; Postoperative Nausea and Vomiting ; Research Design ; Vomiting
Language	English
Publishing date	2019-08-03
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1329844-6
ISSN	1532-8473 ; 0883-9433 ; 1089-9472
ISSN (online)	1532-8473
ISSN	0883-9433 ; 1089-9472
DOI	10.1016/j.jopan.2019.01.006
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Article ; Online: Yunmen (LU 2) combined with neck-seven-acupoint acupuncture for arm numbness caused by cervical spondylotic radiculopathy: A case report.

Zhang, Yi-Mei / Han, Xing-Jun / Wang, Yong-Cheng / Jia, Hong-Ling / Yuan, Xiao-Fen / Meng, Xian-Liang / Li, Zhao-Yu / Zhou, Guo-Feng

Medicine

2021 Volume 100, Issue 22, Page(s) e26151

Abstract: ... We attempted acupuncture at the Yunmen (LU 2) acupoint combined with neck-seven-acupoint under computed ... score was 0.: Lessons: Our report indicates that acupuncture at the LU 2 acupoint combined with neck ... of acupuncture at the LU 2 acupoint can be minimized. ...

Abstract	Rationale: Cervical spondylotic radiculopathy (CSR) is a common sensory, motor, and reflex disorder. Numbness, a common subjective symptom of CSR, lacks objective quantitative indicators and recognized effective treatments, but is also difficult to recover from. We present a case report describing a traditional acupuncture treatment for CSR, utilizing a special acupuncture method and point, namely the Yunmen point. Patient concerns: A 40-year-old woman presented with unilateral arm numbness caused by CSR. Diagnoses: A diagnosis of CSR was made in the orthopedic department of a local hospital. Interventions: We attempted acupuncture at the Yunmen (LU 2) acupoint combined with neck-seven-acupoint under computed tomographic guidance. Outcomes: After 10 times treatment sessions, the patient no longer experienced weakness, coldness, or numbness in the affected upper limb. In addition, the stiffness in the neck and shoulders was reduced. On physical examination, the patient's left brachial plexus traction test was negative; reassessment of the CSR-20-point score scale showed a perfect score, and the visual analog scale score was 0. Lessons: Our report indicates that acupuncture at the LU 2 acupoint combined with neck-seven-acupoint is effective in treating numbness and coldness of the arm, and other neurological symptoms caused by cervical spondylosis. Moreover, with the appropriate acupuncture technique, the risk of acupuncture at the LU 2 acupoint can be minimized.
MeSH term(s)	Acupuncture Therapy/methods ; Adult ; Female ; Humans ; Radiculopathy/etiology ; Radiculopathy/therapy ; Spondylosis/complications
Language	English
Publishing date	2021-06-04
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000026151
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Article ; Online: Mission and challenges of higher education: an interview with G.Q. Max Lu, the president of the University of Surrey.

Wang, Ling / Guo, Zhengtang

National science review

2020 Volume 7, Issue 6, Page(s) 1108–1113

Abstract: ... Professor Max Lu, took this position in 2016 and is also the first scholar of Chinese origin to be ... at the University of Queensland in Australia. Professor Lu is not only a talented leader in education field ... of Sciences, Professor Lu shared his broad and deep perspectives on higher education with ...

Abstract	The University of Surrey (referred to as Surrey hereafter) is one of the renowned universities in the UK that was established on 9 September 1966 with the grant of its Royal Charter and its roots go back to Battersea Polytechnic Institute, founded in 1891. Surrey is the research hub of small satellites, mobile telecommunication and artificial intelligence in Europe. In 2016, Surrey was named as 'University of the Year' in the UK and, in February 2018, Surrey won the Queen's Anniversary Prize for Higher and Further Education (Surrey's fourth award)-the highest national award for the UK universities, in recognition of the outstanding contribution of Surrey to nutrition and health. The president and vice chancellor of Surrey, Professor Max Lu, took this position in 2016 and is also the first scholar of Chinese origin to be the leader of a British university. Before he joined Surrey, he was the provost and senior vice president at the University of Queensland in Australia. Professor Lu is not only a talented leader in education field, but also a distinguished scientist in materials chemistry and nanotechnology area. He has been honored with numerous awards, including the Orica Award, RK Murphy Medal, China International Science and Technology Award and Medal of the Order of Australia, etc. He has been also appointed to the Prime Minister's Council for Science and Technology and the Board of UK Research and Innovation, etc. The rich experience and open-mindedness lead to his profound insights into higher education around the world. Lately elected as a fellow of Royal Academy of Engineering (RAEng) and foreign member of the Chinese Academy of Sciences, Professor Lu shared his broad and deep perspectives on higher education with
Language	English
Publishing date	2020-06-19
Publishing country	China
Document type	Journal Article
ZDB-ID	2745465-4
ISSN	2053-714X ; 2053-714X
ISSN (online)	2053-714X
ISSN	2053-714X
DOI	10.1093/nsr/nwaa072
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Article ; Online: Van Vleck paramagnetism in undoped and Lu-doped bulk ceria.

Varenik, Maxim / Zhang, Xiao-Dong / Leitus, Gregory / Yavo, Nimrod / Carmieli, Raanan / Wachtel, Ellen / Guo, Xin / Lubomirsky, Igor

Physical chemistry chemical physics : PCCP

2018 Volume 20, Issue 42, Page(s) 27019–27024

Abstract: ... susceptibility decreases linearly with Lu content, and becomes diamagnetic at 30 mol% Lu. The Curie-Weiss ... from Ce3+ could be detected. The fact that the magnetization decreases with Lu content, even ...

Abstract	The magnetic properties of undoped, bulk CeO2 are not fully understood. In contrast to nanocrystalline ceria that exhibits paramagnetism attributed to Ce3+ at grain surfaces, bulk ceria is weakly paramagnetic, despite the absence of magnetic ions. In the present work, the magnetic susceptibility of bulk ceria ceramics doped with Lu3+, which has neither spin nor orbital angular momentum, was measured in order to assess the relative contributions of the crystal lattice, residual Ce3+ and oxygen vacancies to the overall bulk magnetization. We observed a magnetic response consisting of two parts: temperature independent (5-300 K) magnetic susceptibility, and Curie-Weiss paramagnetism. The temperature independent susceptibility decreases linearly with Lu content, and becomes diamagnetic at 30 mol% Lu. The Curie-Weiss magnetism visible at low temperatures was identified as resulting from a few ppm of Fe contaminant. However, Fe contamination does not contribute to the temperature independent paramagnetism. No contribution from Ce3+ could be detected. The fact that the magnetization decreases with Lu content, even though the concentration of oxygen vacancies, and the lattice defects associated with them, increases, indicates that neither is coupled to the magnetic field. Weak, temperature-independent paramagnetism in non-metals is usually attributed to a second order, Van Vleck-type magnetization. However, Van Vleck paramagnetism requires that the population of the first excited state be constant within the range of temperatures investigated. We discuss possible modifications of the large band gap electronic structure of undoped ceria which could account for our observations.
Language	English
Publishing date	2018-10-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/c8cp04953j
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Article ; Online: Ventral Morphology of the Non-Trilobite Artiopod Retifacies abnormalis Hou, Chen & Lu, 1989, from the Early Cambrian Chengjiang Biota, China

Maoyin Zhang / Yu Liu / Xianguang Hou / Javier Ortega-Hernández / Huijuan Mai / Michel Schmidt / Roland R. Melzer / Jin Guo

Biology, Vol 11, Iss 8, p

2022 Volume 1235

Abstract: ... Lu, 1989, which is distinguished by the presence of mesh-like ornamentation on its dorsal exoskeleton ...

Abstract	The artiopodans represent a diverse group of euarthropods with a typically flattened dorsal exoskeleton that covers numerous pairs of biramous ventral appendages, and which are ubiquitous faunal components of the 518-million-year-old Chengjiang Lagerstätte in South China. Despite their abundance, several Chengjiang artiopodans remain poorly known, such as the large euarthropoda Retifacies abnormalis, Hou, Chen & Lu, 1989, which is distinguished by the presence of mesh-like ornamentation on its dorsal exoskeleton. Although only a few ventral details were described in a single study in 25 years, it has been frequently featured in phylogenetic analyses that explore the relationships between Cambrian euarthropods. Here, we employ micro-CT and fluorescent microphotography to investigate the exceptionally preserved ventral morphology of R. abnormalis and explore its phylogenetic implications through maximum parsimony and Bayesian inference. Detailed morphology revealed here better supports R. abnormalis as a sister group to the diminutive artiopod Pygmaclypeatus daziensis , also known from Chengjiang, and strengthens the close relationship of these taxa that have been suggested by previous studies as early-branching representatives of Trilobitomorpha. Cephalic appendages suggest this animal might be a scavenger, possibly feeding on soft-bodied organisms. Different pairs of pygidial appendages suggest an anamorphic post-embryonic ontogeny, which adds to the understanding of the developmental mode of Cambrian artiopods, and further supports the statement that post-hatching segment addition occurred in the ancestor of Euarthropoda.
Keywords	ventral morphology ; Cambrian artiopoda ; micro computed tomography ; Trilobitomorpha ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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