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Article ; Online: PFO closure: Keep it safe and effective first!

Montalescot, Gilles / Hauguel-Moreau, Marie / Reibel, Iphigenie

2024 Volume 117, Issue 2, Page(s) 169–170

MeSH term(s)	Humans ; Stroke ; Treatment Outcome ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/diagnostic imaging ; Foramen Ovale, Patent/surgery ; Cardiac Catheterization/adverse effects ; Septal Occluder Device ; Secondary Prevention
Language	English
Publishing date	2024-01-06
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2408778-6
ISSN	1875-2128 ; 1875-2136
ISSN (online)	1875-2128
ISSN	1875-2136
DOI	10.1016/j.acvd.2023.12.003
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Article ; Online: Case report of a very late dual coronary stent thrombosis in a patient with coronavirus disease 2019.

Hauguel-Moreau, Marie / Lannou, Simon / Bergez, Léa / Mansencal, Nicolas

European heart journal. Case reports

2021 Volume 5, Issue 6, Page(s) ytab114

Abstract: Background: Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability and a high rate of thrombosis. Few cases of coronary stent thrombosis associated with COVID-19 have been reported.: Case summary: In this report, we describe the ... ...

Abstract	Background: Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability and a high rate of thrombosis. Few cases of coronary stent thrombosis associated with COVID-19 have been reported. Case summary: In this report, we describe the case of a 65-year-old man with a history of coronary artery disease (CAD) who was admitted following an out-of-hospital cardiac arrest related to an ST-segment elevation myocardial infarction revealing a very late dual coronary stent thrombosis of the left anterior descending and posterior descending arteries. Ten days prior to admission, he was diagnosed with COVID-19 pneumonia and treated with dexamethasone, which led to rapid clinical improvement. After resuscitation, coronary angiography revealed an acute thrombotic occlusion in the two previous drug-eluting stents (implanted in 2010 and 2018), with a high thrombus burden. He was successfully treated by percutaneous coronary intervention. The patient did not present any further complications during his hospital stay and was transferred to a cardiac rehabilitation centre. Discussion: Dual stent thrombosis is an exceptional event highlighting the high procoagulant state promoted by coronavirus 19. This case suggests that strengthening of antithrombotic therapy in CAD patients presenting with COVID-19 should be discussed.
Language	English
Publishing date	2021-06-07
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytab114
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Article: Cardiologie interventionnelle chez le sujet âgé.

Pépin, Marion / Hauguel-Moreau, Marie / Grognet, Alix / Decaix, Théodore

Soins. Gerontologie

2020 Volume 26, Issue 147, Page(s) 12–15

Abstract: Interventional cardiology is increasingly being offered to frail elderly people thanks to significant technical progress. Transcatheter aortic valve implantation allows the treatment of aortic stenosis by implanting an aortic bioprosthesis through a ... ...

Title translation	Interventional cardiology in the elderly, at the time of TAVI and left atrial appendage occlusion.
Abstract	Interventional cardiology is increasingly being offered to frail elderly people thanks to significant technical progress. Transcatheter aortic valve implantation allows the treatment of aortic stenosis by implanting an aortic bioprosthesis through a catheter, without surgery. The left atrial appendage occlusion limits the risk of ischemic stroke in patients with atrial fibrillation who have a contraindication to anticoagulants. These procedures remain invasive and must be proposed after multidisciplinary consultation.
MeSH term(s)	Aged ; Aortic Valve Stenosis/surgery ; Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Atrial Fibrillation/complications ; Atrial Fibrillation/therapy ; Cardiology ; Humans ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
Language	French
Publishing date	2020-11-01
Publishing country	France
Document type	Journal Article
ZDB-ID	2246755-5
ISSN	1268-6034
ISSN	1268-6034
DOI	10.1016/j.sger.2020.10.003
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Article ; Online: Managing Pregnancy as an Interventional Cardiologist Fellow-in-Training: My Experience With a Simulator.

Hauguel-Moreau, Marie / Adjedj, Julien

Journal of the American College of Cardiology

2016 Volume 68, Issue 17, Page(s) 1916–1919

MeSH term(s)	Adult ; Cardiology/education ; Career Mobility ; Computer Simulation ; Education, Medical, Graduate ; Female ; Humans ; Pregnancy
Language	English
Publishing date	2016--25
Publishing country	United States
Document type	Editorial
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2016.09.002
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Article ; Online: SARS-CoV-2 in coronary blood from thrombus aspiration in a patient with myocardial infarction.

Hauguel-Moreau, Marie / Mansencal, Nicolas / Gault, Elyanne / Prati, Giulio / Dubourg, Olivier / Annane, Djillali

Coronary artery disease

2021 Volume 33, Issue 4, Page(s) 335–336

MeSH term(s)	COVID-19/complications ; Coronary Angiography ; Coronary Thrombosis/complications ; Coronary Thrombosis/diagnostic imaging ; Coronary Thrombosis/therapy ; Humans ; Myocardial Infarction/therapy ; Percutaneous Coronary Intervention ; SARS-CoV-2 ; Thrombectomy ; Treatment Outcome
Language	English
Publishing date	2021-11-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1047268-x
ISSN	1473-5830 ; 0954-6928
ISSN (online)	1473-5830
ISSN	0954-6928
DOI	10.1097/MCA.0000000000001107
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Article ; Online: Impact of neighbourhood socio-economic status on cardiovascular risk factors in a French urban population.

Hergault, Hélène / Hauguel-Moreau, Marie / Pépin, Marion / Beauchet, Alain / Josseran, Loïc / Rodon, Christophe / Gaye, Bamba / Dubourg, Olivier / Mansencal, Nicolas

European journal of preventive cardiology

2022 Volume 29, Issue 16, Page(s) 2142–2144

MeSH term(s)	Humans ; Urban Population ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Economic Status ; Risk Factors ; Residence Characteristics ; Heart Disease Risk Factors ; Socioeconomic Factors
Language	English
Publishing date	2022-07-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2626011-6
ISSN	2047-4881 ; 2047-4873
ISSN (online)	2047-4881
ISSN	2047-4873
DOI	10.1093/eurjpc/zwac155
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Zs.A 4686: Show issues

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Article ; Online: Relevance of Cardiovascular Risk Factors Screening in People Aged over 65 Years: Results from a Large French Urban Population (The CARVAR92 Study).

Pépin, Marion / Hauguel-Moreau, Marie / Hergault, Hélène / Beauchet, Alain / Rodon, Christophe / Cudennec, Tristan / Teillet, Laurent / Dubourg, Olivier / Mansencal, Nicolas

Gerontology

2022 Volume 68, Issue 12, Page(s) 1358–1365

Abstract: Background: Cardiovascular disease is the leading cause of death and disability in older people. Traditional cardiovascular risk factors (CVRFs) still have an impact on cardiovascular risk among older people. Nevertheless, screening campaigns rarely ... ...

Abstract	Background: Cardiovascular disease is the leading cause of death and disability in older people. Traditional cardiovascular risk factors (CVRFs) still have an impact on cardiovascular risk among older people. Nevertheless, screening campaigns rarely target subjects aged over 65 years. This study aimed to assess the distribution and relevance of conventional CVRF screening in people aged over 65 years. Methods: Between 2007 and 2018, among a screening CVRF campaign in the western suburbs of Paris (32,692 subjects), we individualized 6,577 subjects aged 65 years and over. All conventional CVRFs have been systematically assessed. Results: The screening allowed to suspect hypertension in a larger proportion of subjects over 65 years compared to subjects under 65 years (27% vs. 18%, p < 0.0001). Hypertension control was higher in women compared to men but not significantly different in the age-groups (p = 0.91). Screening for diabetes mellitus was positive in 3% of older subjects and 2.4% in younger (p = 0.005). Risk assessment with dedicated score (SCORE O.P.) allowed to move toward a low-risk estimation, resulting in the diminution of intermediate risk group in women over 65 years (from 68 to 61%, p < 0.001). Conclusions: Screening CVRFs especially hypertension remains relevant in people aged over 65 years as it enables to detect unknown CVRFs in numerous subjects. Increasing awareness of CVRFs may be the first step to CVRF control, which is known to be efficient on cardiovascular mortality and functional autonomy in later life.
MeSH term(s)	Male ; Female ; Humans ; Aged ; Urban Population ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Risk Factors ; Heart Disease Risk Factors ; Hypertension/diagnosis ; Hypertension/epidemiology
Language	English
Publishing date	2022-03-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	193798-4
ISSN	1423-0003 ; 0304-324X
ISSN (online)	1423-0003
ISSN	0304-324X
DOI	10.1159/000521995
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Article ; Online: Prevalence of prediabetes and undiagnosed diabetes in a large urban middle-aged population: the CARVAR 92 cohort.

Hauguel-Moreau, Marie / Hergault, Hélène / Cazabat, Laure / Pépin, Marion / Beauchet, Alain / Aïdan, Vincent / Ouadahi, Mounir / Josseran, Loïc / Hage, Mirella / Rodon, Christophe / Dubourg, Olivier / Massy, Ziad / Mansencal, Nicolas

Cardiovascular diabetology

2023 Volume 22, Issue 1, Page(s) 31

Abstract: Background: The aim of this study was to assess the prevalence of prediabetes and unknown diabetes and its long-term change in a large middle-aged urban population.: Methods: We conducted a screening campaign between 2007 and 2018 for cardiovascular ... ...

Abstract	Background: The aim of this study was to assess the prevalence of prediabetes and unknown diabetes and its long-term change in a large middle-aged urban population. Methods: We conducted a screening campaign between 2007 and 2018 for cardiovascular risk factors in the western suburbs of Paris including subjects aged 40-70 (CARVAR 92). Among subjects who reported no previous diabetes, prediabetes and undiagnosed diabetes were defined as follows: fasting plasma glucose (FPG) ≥ 6.1 mmol/l (110 mg/dl) and < 7 mmol/l (126 mg/dl) for prediabetes according to WHO criteria (FPG between 5.6 and 6.9 mmol/l according to ADA criteria) and FPG ≥ 7.0 mmol/l for undiagnosed diabetes. Results: Of the 32,721 subjects in the CARVAR 92 cohort, 32,675 were included in this analysis. The median age of the patients was 56 years [30, 94], 45.4% were male, 5.9% had known diabetes, 36.4% were overweight and 18.7% obese. Among patients without previously known diabetes (n = 30,759), 8.1% had prediabetes according to WHO criteria (27.2% according to ADA criteria) and 2.3% had diabetes. Subjects with prediabetes and unknown diabetes were more likely to be male, older, and overweight or obese than non-diabetic subjects. From 2007 to 2018, the prevalence of prediabetes, unknown diabetes, and known diabetes decreased, except for prediabetes which remained stable for people aged 55-64. Conclusion: The prevalence of prediabetes and unknown diabetes remains high but decreased during a 12-year period. About one-quarter of diabetes cases remain undiagnosed. Our results highlight that there is still a room for screening and cardiovascular prevention campaigns. Trial registration: IRB00012437.
MeSH term(s)	Middle Aged ; Humans ; Male ; Female ; Prediabetic State/diagnosis ; Prediabetic State/epidemiology ; Overweight ; Prevalence ; Urban Population ; Blood Glucose ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/epidemiology ; Obesity ; Fasting ; Risk Factors
Chemical Substances	Blood Glucose
Language	English
Publishing date	2023-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2093769-6
ISSN	1475-2840 ; 1475-2840
ISSN (online)	1475-2840
ISSN	1475-2840
DOI	10.1186/s12933-023-01761-3
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Article ; Online: Comparison of three echo-guidance techniques in percutaneous patent foramen ovale closure for stroke prevention: Conventional transoesophageal, microprobe transoesophageal and intracardiac echocardiography.

Reibel, Iphigénie / Hauguel-Moreau, Marie / Guedeney, Paul / Hage, Georges / Hammoudi, Nadjib / Duthoit, Guillaume / Zeitouni, Michel / Lattuca, Benoit / Kernéis, Mathieu / Collet, Jean-Philippe / Silvain, Johanne / Montalescot, Gilles

Archives of cardiovascular diseases

2023

Abstract: Background: Recent randomized trials have demonstrated a consistent reduction in recurrent stroke after percutaneous transcatheter patent foramen ovale closure versus medical therapy in patients with recent cryptogenic stroke.: Aim: To compare the ... ...

Abstract	Background: Recent randomized trials have demonstrated a consistent reduction in recurrent stroke after percutaneous transcatheter patent foramen ovale closure versus medical therapy in patients with recent cryptogenic stroke. Aim: To compare the safety and efficacy of intracardiac echocardiography-guided and microprobe transoesophageal echocardiography-guided patent foramen ovale closure under local anaesthesia with transoesophageal echocardiography-guided patent foramen ovale closure under general anaesthesia. Methods: This prospective observational single-centre study included 194 consecutive patients scheduled for patent foramen ovale closure for secondary prevention of stroke from February 2018 to December 2019. Patients were asked to choose between an intracardiac echocardiography-guided, microprobe transoesophageal echocardiography-guided or transoesophageal echocardiography-guided procedure. The primary endpoint was the rate of successful closure at 6 months, defined as correct positioning of the device without severe shunt on 6-month contrast echocardiography. Results: Successful closure was high and did not differ between groups: 97.8% (95% confidence interval 88.5-99.9%) in the intracardiac echocardiography-guided group versus 96.9% (95% confidence interval 83.8-99.9%) in the microprobe transoesophageal echocardiography-guided group and 99.1% (95% confidence interval 95.3-99.9%) in the transoesophageal echocardiography-guided group (P=0.63). Adverse events related to patent foramen ovale closure were low and did not differ between groups. Conclusion: Our preliminary real-world experience suggests good efficacy and safety with intracardiac echocardiography and microprobe transoesophageal echocardiography guidance compared with conventional transoesophageal echocardiography guidance for percutaneous transcatheter patent foramen ovale closure in recurrent stroke prevention.
Language	English
Publishing date	2023-09-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2408778-6
ISSN	1875-2128 ; 1875-2136
ISSN (online)	1875-2128
ISSN	1875-2136
DOI	10.1016/j.acvd.2023.08.006
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Article ; Online: Screening of Native Valvular Heart Disease Using a Pocket-Sized Transthoracic Echocardiographic Device.

Kikoïne, John / Hauguel-Moreau, Marie / Hergault, Hélène / Aidan, Vincent / Ouadahi, Mounir / Dubourg, Olivier / Szymanski, Catherine / Mansencal, Nicolas

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

2021 Volume 35, Issue 2, Page(s) 196–202

Abstract: Background: The authors assessed the performance of pocket-sized transthoracic echocardiography (pTTE) compared with standard transthoracic echocardiography (sTTE) and auscultation for early screening of valvular heart disease (VHD). Early diagnosis of ... ...

Abstract	Background: The authors assessed the performance of pocket-sized transthoracic echocardiography (pTTE) compared with standard transthoracic echocardiography (sTTE) and auscultation for early screening of valvular heart disease (VHD). Early diagnosis of significant VHD is a challenge, but it enables appropriate follow-up and implementation of the best therapeutic strategy. Methods: sTTE, pTTE, and auscultation were performed by three different experienced physicians on 284 unselected patients. All cases of VHD detected by each of these three techniques were noted. sTTE was the gold standard. Each physician performed one examination and was blinded to the results of other examinations. Results: We diagnosed a total of 301 cases of VHD, with a large predominance of regurgitant lesions: 269 cases (89.3%) of regurgitant VHD and 32 (10.7%) of stenotic VHD. pTTE was highly sensitive (85.7%) and specific (97.9%) for screening for VHD, while auscultation detected only 54.1%. All significant cases of VHD (at least mild severity) were detected on pTTE. The weighted κ coefficient between pTTE and sTTE for the assessment of mitral regurgitation was 0.71 (95% CI, 0.70-0.72), indicating good agreement. The weighted κ coefficients between pTTE and sTTE for the assessment of aortic regurgitation and aortic stenosis were 0.97 (95% CI, 0.96-0.98) and 0.98 (95% CI, 0.97-0.99), respectively, indicating excellent agreement. Conclusions: pTTE performed by physicians with level III competency in echocardiography is reliable for identifying significant VHD and should be proposed as a new screening tool.
MeSH term(s)	Aortic Valve Insufficiency ; Aortic Valve Stenosis/diagnostic imaging ; Echocardiography/methods ; Heart Valve Diseases/diagnostic imaging ; Humans ; Mitral Valve Insufficiency/diagnostic imaging
Language	English
Publishing date	2021-08-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1035622-8
ISSN	1097-6795 ; 0894-7317
ISSN (online)	1097-6795
ISSN	0894-7317
DOI	10.1016/j.echo.2021.08.013
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