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  1. Article: Erratum: Yuan, W., et al. Genome-Wide Identification of Banana

    Yuan, Weina / Liu, Jing / Takáč, Tomáš / Chen, Houbin / Li, Xiaoquan / Meng, Jian / Tan, Yehuan / Ning, Tong / He, Zhenting / Yi, Ganjun / Xu, Chunxiang

    Plants (Basel, Switzerland)

    2021  Volume 10, Issue 4

    Abstract: The authors wish to make the following corrections to this paper [ ... ]. ...

    Abstract The authors wish to make the following corrections to this paper [...].
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants10040654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Traditional Chinese Medicine Shen-Yuan-Dan (SYD) Improves Hypoxia-Induced Cardiomyocyte Apoptosis in Neonatal Rats by Upregulating miR-24/Bim Pathway.

    Chu, Fuyong / Yan, Xue / Xiong, Xingjiang / Zhou, Mingxue / Tan, Yupei / Li, Yixuan / Liu, Wei / Liu, Hongxu

    Evidence-based complementary and alternative medicine : eCAM

    2022  Volume 2022, Page(s) 5804187

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2022-02-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2022/5804187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.

    Iyaswamy, A / Krishnamoorthi, S K / Liu, Y W / Song, J X / Kammala, A K / Sreenivasmurthy, S G / Malampati, S / Tong, B C K / Selvarasu, K / Cheung, K H / Lu, J H / Tan, J Q / Huang, C Y / Durairajan, S S K / Li, M

    Frontiers in pharmacology

    2020  Volume 11, Page(s) 584770

    Abstract: ... medicine prescription Yuan-Hu Zhi Tong (YZT) in treating AD, and it has substantiated the ...

    Abstract Alzheimer's disease (AD) is characterized by memory dysfunction, Aβ plaques together with phosphorylated tau-associated neurofibrillary tangles. Unfortunately, the present existing drugs for AD only offer mild symptomatic cure and have more side effects. As such, developments of effective, nontoxic drugs are immediately required for AD therapy. Present study demonstrates a novel role of Chinese medicine prescription Yuan-Hu Zhi Tong (YZT) in treating AD, and it has substantiated the
    Language English
    Publishing date 2020-10-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.584770
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Traditional Chinese Medicine Shen-Yuan-Dan (SYD) Improves Hypoxia-Induced Cardiomyocyte Apoptosis in Neonatal Rats by Upregulating miR-24/Bim Pathway

    Fuyong Chu / Xue Yan / Xingjiang Xiong / Mingxue Zhou / Yupei Tan / Yixuan Li / Wei Liu / Hongxu Liu

    Evidence-Based Complementary and Alternative Medicine, Vol

    2022  Volume 2022

    Abstract: ... to date. The present study aimed to investigate the role of traditional Chinese medicine shen-yuan-dan ...

    Abstract Background: Acute myocardial infarction (AMI) is the leading cause of malignant arrhythmia, heart failure, and sudden death. However, safe and effective drugs for the treatment of AMI are unavailable to date. The present study aimed to investigate the role of traditional Chinese medicine shen-yuan-dan (SYD) in hypoxia-induced cardiomyocyte apoptosis in neonatal rats. In addition, the study explored the possible mechanism through which SYD could reduce myocardial ischemia apoptosis and regulate the expression of the miR-24/Bim pathway. Methods: Hypoxia-induced neonatal rat cardiomyocytes were used for the experiments. These cardiomyocytes were transfected with an miR-24 mimic and an miR-24 inhibitor and then cocultured with SYD-containing serum. MTT and lactate dehydrogenase (LDH) assays, AnnexinV/PI double staining, flow cytometry, and TUNEL staining were used to determine the cell viability and apoptosis under hypoxic conditions. Furthermore, the expression level of Bim in the hypoxia-induced cardiomyocytes was determined through western blotting and quantitative real-time polymerase chain reaction. Results: After 48 h of hypoxia, LDH and creatine phosphokinase (CPK) activities increased, cell viability decreased, and miR-24 expression upregulated in the cardiomyocytes. SYD alleviated hypoxia-induced cardiomyocyte injury, decreased LDH and CPK activities, increased cell viability, and reduced apoptosis in the neonatal rat cardiomyocytes. Moreover, SYD could upregulate miR-24 expression and downregulate Bim expression. Upregulation of miR-24 expression significantly enhanced the effect of SYD, thereby improving myocardial cell apoptosis. Dual-luciferase reporter assay and western blot analysis confirmed that Bim was a direct target of miR-24. Conclusion: SYD treatment reduces hypoxia-induced myocardial apoptosis by upregulating miR-24 expression. This study provides new insights into the molecular mechanism underlying the therapeutic potential of SYD in promoting the recovery of myocardial function and delaying ...
    Keywords Other systems of medicine ; RZ201-999
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book: Yuan dai juan

    Li, Yi / Tan, Zhixiang

    (Zhonghua yi shu tong shi ; / Li Xifan zong zhubian[...])

    2006  

    Author's details Tan Zhixiang, Li Yi ben juan zhubian
    Series title Zhonghua yi shu tong shi
    / Li Xifan zong zhubian[...]
    Language Chinese
    Size 7, 427 p, Ill
    Edition Di 1 ban
    Publisher Beijing shifan daxue chubanshe
    Publishing place Beijing
    Document type Book
    ISBN 7303076956 ; 9787303076956
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article ; Online: Future changes in Yuan River ecohydrology: Individual and cumulative impacts of climates change and cascade hydropower development on runoff and aquatic habitat quality.

    Wen, Xin / Liu, Zhehua / Lei, Xiaohui / Lin, Rongjie / Fang, Guohua / Tan, Qiaofeng / Wang, Chao / Tian, Yu / Quan, Jin

    The Science of the total environment

    2018  Volume 633, Page(s) 1403–1417

    Abstract: ... the potential future changes in streamflow and fish habitat quality in the Yuan River and quantify ...

    Abstract The eco-hydrological system in southwestern China is undergoing great changes in recent decades owing to climate change and extensive cascading hydropower exploitation. With a growing recognition that multiple drivers often interact in complex and nonadditive ways, the purpose of this study is to predict the potential future changes in streamflow and fish habitat quality in the Yuan River and quantify the individual and cumulative effect of cascade damming and climate change. The bias corrected and spatial downscaled Coupled Model Intercomparison Project Phase 5 (CMIP5) General Circulation Model (GCM) projections are employed to drive the Soil and Water Assessment Tool (SWAT) hydrological model and to simulate and predict runoff responses under diverse scenarios. Physical habitat simulation model is established to quantify the relationship between river hydrology and fish habitat, and the relative change rate is used to assess the individual and combined effects of cascade damming and climate change. Mean annual temperature, precipitation and runoff in 2015-2100 show an increasing trend compared with that in 1951-2010, with a particularly pronounced difference between dry and wet years. The ecological habitat quality is improved under cascade hydropower development since that ecological requirement has been incorporated in the reservoir operation policy. As for middle reach, the runoff change from January to August is determined mainly by damming, and climate change influence becomes more pronounced in dry seasons from September to December. Cascade development has an effect on runoff of lower reach only in dry seasons due to the limited regulation capacity of reservoirs, and climate changes have an effect on runoff in wet seasons. Climate changes have a less significant effect on fish habitat quality in middle reach than damming, but a more significant effect in lower reach. In addition, the effect of climate changes on fish habitat quality in lower reach is high in dry seasons but low in flood seasons.
    Language English
    Publishing date 2018-08-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2018.03.309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease

    A. Iyaswamy / S. K. Krishnamoorthi / Y. W. Liu / J. X. Song / A. K. Kammala / S. G. Sreenivasmurthy / S. Malampati / B. C. K. Tong / K. Selvarasu / K. H. Cheung / J. H. Lu / J. Q. Tan / C. Y. Huang / S. S. K. Durairajan / M. Li

    Frontiers in Pharmacology, Vol

    2020  Volume 11

    Abstract: ... medicine prescription Yuan-Hu Zhi Tong (YZT) in treating AD, and it has substantiated the in vivo ...

    Abstract Alzheimer’s disease (AD) is characterized by memory dysfunction, Aβ plaques together with phosphorylated tau-associated neurofibrillary tangles. Unfortunately, the present existing drugs for AD only offer mild symptomatic cure and have more side effects. As such, developments of effective, nontoxic drugs are immediately required for AD therapy. Present study demonstrates a novel role of Chinese medicine prescription Yuan-Hu Zhi Tong (YZT) in treating AD, and it has substantiated the in vivo effectiveness of YZT in two different transgenic mice models of AD, namely P301S tau and 3XTg-AD mice. Oral treatment of YZT significantly ameliorates motor dysfunction as well as promotes the clearance of aggregated tau in P301S tau mice. YZT improves the cognitive function and reduces the insoluble tau aggregates in 3XTg-AD mice model. Furthermore, YZT decreases the insoluble AT8 positive neuron load in both P301S tau and 3XTg-AD mice. Using microarray and the “Connectivity Map” analysis, we determined the YZT-induced changes in expression of signaling molecules and revealed the potential mechanism of action of YZT. YZT might regulate ubiquitin proteasomal system for the degradation of tau aggregates. The research results show that YZT is a potential drug candidate for the therapy of tau pathogenesis and memory decline in AD.
    Keywords Alzheimer’s disease ; P301S tau mice ; neurofibrillary tangles ; Chinese medicine ; yuan-hu zhi tong ; microarray ; Therapeutics. Pharmacology ; RM1-950
    Subject code 572
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Future changes in Yuan River ecohydrology: Individual and cumulative impacts of climates change and cascade hydropower development on runoff and aquatic habitat quality

    Wen, Xin / Chao Wang / Guohua Fang / Jin Quan / Qiaofeng Tan / Rongjie Lin / Xiaohui Lei / Yu Tian / Zhehua Liu

    Science of the total environment. 2018 Aug. 15, v. 633

    2018  

    Abstract: ... the potential future changes in streamflow and fish habitat quality in the Yuan River and quantify ...

    Abstract The eco-hydrological system in southwestern China is undergoing great changes in recent decades owing to climate change and extensive cascading hydropower exploitation. With a growing recognition that multiple drivers often interact in complex and nonadditive ways, the purpose of this study is to predict the potential future changes in streamflow and fish habitat quality in the Yuan River and quantify the individual and cumulative effect of cascade damming and climate change. The bias corrected and spatial downscaled Coupled Model Intercomparison Project Phase 5 (CMIP5) General Circulation Model (GCM) projections are employed to drive the Soil and Water Assessment Tool (SWAT) hydrological model and to simulate and predict runoff responses under diverse scenarios. Physical habitat simulation model is established to quantify the relationship between river hydrology and fish habitat, and the relative change rate is used to assess the individual and combined effects of cascade damming and climate change. Mean annual temperature, precipitation and runoff in 2015–2100 show an increasing trend compared with that in 1951–2010, with a particularly pronounced difference between dry and wet years. The ecological habitat quality is improved under cascade hydropower development since that ecological requirement has been incorporated in the reservoir operation policy. As for middle reach, the runoff change from January to August is determined mainly by damming, and climate change influence becomes more pronounced in dry seasons from September to December. Cascade development has an effect on runoff of lower reach only in dry seasons due to the limited regulation capacity of reservoirs, and climate changes have an effect on runoff in wet seasons. Climate changes have a less significant effect on fish habitat quality in middle reach than damming, but a more significant effect in lower reach. In addition, the effect of climate changes on fish habitat quality in lower reach is high in dry seasons but low in flood seasons.
    Keywords aquatic habitat ; climate change ; dams (hydrology) ; dry season ; fish ; General Circulation Models ; issues and policy ; rivers ; runoff ; simulation models ; Soil and Water Assessment Tool model ; stream flow ; temperature ; water power ; wet season ; China
    Language English
    Dates of publication 2018-0815
    Size p. 1403-1417.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2018.03.309
    Database NAL-Catalogue (AGRICOLA)

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  9. Book ; Online ; E-Book: Atlas of pigmentary skin disorders

    Tan, Kakushin / Zhu, Wen-Yuan

    2023  

    Author's details edited by Cheng Tan, Wen-Yuan Zhu
    MeSH term(s) Pigmentation Disorders. ; Skin Diseases/pathology. ; Skin Pigmentation.
    Keywords Pigmentation disorders
    Subject code 405
    Language English
    Dates of publication 2023-2023
    Size 1 online resource (537 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-19-5634-0 ; 9789811956331 ; 978-981-19-5634-8 ; 9811956332
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article: [Comparative study on infrared radiation spectrum of yuan point and Xiahe point of the large intestine channel in the patient of ulcerative colitis].

    Wu, Huan-gan / Yao, Yi / Shen, Xue-yong / Tan, Lin-ying / Shi, Yin / Yang, Yun / Liu, Hui-rong / Zheng, Shi

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2008  Volume 28, Issue 1, Page(s) 49–55

    Abstract: Objective: To probe the diagnostic value of the infrared radiation spectrum of acupoint for ulcerative colitis (UC).: Methods: A high sensitivity PHE 201 infrared spectrum instrument was used to determine the infrared radiation spectrum of Hegu (LI 4) ...

    Abstract Objective: To probe the diagnostic value of the infrared radiation spectrum of acupoint for ulcerative colitis (UC).
    Methods: A high sensitivity PHE 201 infrared spectrum instrument was used to determine the infrared radiation spectrum of Hegu (LI 4) and Shangjuxu (ST 37) in 34 cases of UC.
    Results: Of 59 waves detected, there were significant differences in infrared radiation intensity of 28 different waves between the healthy people and the patients with UC in right Hegu (LI 4) (P < 0.05 or P < 0.01) and 13 waves in left Hegu (LI 4) (P < 0.05); there were significant differences in 16 different waves in right Shangjuxu (ST 37) (P < 0.05 or P < 0.01) and in 17 waves in left Shangjuxu (ST 37) (P < 0.05 or P < 0.01); there was a significant difference in 18 waves between right and left Hegu (LI 4) of the patients (P < 0.05 or P < 0.01) and 7 waves between right and left Hegu (LI 4) of the healthy people (P < 0.05). There was a significant difference in 4 waves between right and left Shangjuxu (ST 37) of the patients and one wave between right and left Shangjuxu (ST 37) of the healthy people (P < 0.01).
    Conclusion: Both Hegu (LI 4) and Shangjuxu (ST 37) show changes of infrared radiation spectrum when the intestine gets lesion, and Hegu (LI 4) can better show the change.
    MeSH term(s) Acupuncture Points ; Acupuncture Therapy ; Adult ; Colitis, Ulcerative/therapy ; Female ; Humans ; Infrared Rays ; Intestine, Large/anatomy & histology ; Male ; Middle Aged
    Language Chinese
    Publishing date 2008-01
    Publishing country China
    Document type Comparative Study ; English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 0255-2930
    ISSN 0255-2930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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