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Article: CAD/CAM design and 3D printing of a personalised rapid palatal expander for maxillary transverse deficiency.

Wang, Chunlin / Xiang, Xiaosong / Mao, Qin / Liu, Conghua

JPMA. The Journal of the Pakistan Medical Association

2024 Volume 74, Issue 1, Page(s) 153–157

Abstract: Bone -borne ra pid ma xilla ry expansion appliances can achieve skeletal expansion while avoiding the undesirable dental side effec ts caused by a conventional rapid palatal expansion appliance. Typically, t hese (bone-bo rne appliances) included ... ...

Abstract	Bone -borne ra pid ma xilla ry expansion appliances can achieve skeletal expansion while avoiding the undesirable dental side effec ts caused by a conventional rapid palatal expansion appliance. Typically, t hese (bone-bo rne appliances) included prefabricated devices, which can have limitations such as inadequate palatal adaptation leading to anch orage los s. In addit ion, a s bone thickness is not accounted for, prefabricated expanders cannot ensure the primary stability of the mini-implants. These disadvantages can be overcom e by customisation. This repor t aims to describe the digital design and three-dimensional printing workflow for constructing a personali sed M iniscrewassisted rapid palatal expansion (pMARPE) and present a case depicting its application in a 27-year-old female with 5.0 mm t ransverse discrepancy b etween the maxilla and the mandible. The result demonstrated that the pMARPE could be manufactured without the need for conventional impre s sion or laborator y p rocedures and effec tively e xpanded the palate of an ad ult pat ient with maxillar y transverse deficiency.
MeSH term(s)	Female ; Humans ; Adult ; Maxilla ; Palatal Expansion Technique ; Tooth ; Palate ; Printing, Three-Dimensional
Language	English
Publishing date	2024-01-13
Publishing country	Pakistan
Document type	Case Reports
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
DOI	10.47391/JPMA.8363
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.B 845: Show issues

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Article ; Online: Increasing Charge Carrier Mobility through Modifications of Terminal Groups of Y6: A Theoretical Study.

Xiang, Yunjie / Xu, Chunlin / Zheng, Shaohui

International journal of molecular sciences

2023 Volume 24, Issue 10

Abstract: The applications of non-fullerene acceptor Y6 with a new type of ... ...

Abstract	The applications of non-fullerene acceptor Y6 with a new type of A
Language	English
Publishing date	2023-05-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24108610
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Article ; Online: CAD/CAM design and 3D printing of a personalised rapid palatal expander for maxillary transverse deficiency

Chunlin Wang / Xiaosong Xiang / Qin Mao / Conghua Liu

Journal of the Pakistan Medical Association, Vol 74, Iss

2023 Volume 1

Abstract: Bone-borne rapid maxillary expansion appliances can achieve skeletal expansion while avoiding the undesirable dental side effects caused by a conventional rapid palatal expansion appliance. Typically, these (bone-borne appliances) included prefabricated ... ...

Abstract	Bone-borne rapid maxillary expansion appliances can achieve skeletal expansion while avoiding the undesirable dental side effects caused by a conventional rapid palatal expansion appliance. Typically, these (bone-borne appliances) included prefabricated devices, which can have limitations such as inadequate palatal adaptation leading to anchorage loss. In addition, as bone thickness is not accounted for, prefabricated expanders cannot ensure the primary stability of the mini-implants. These disadvantages can be overcome by customisation. This report aims to describe the digital design and three-dimensional printing workflow for constructing a personalised rapid palatal expander (pMARPE) and present a case depicting its application in a 27-year-old female with 5.0 mm transverse discrepancy between the maxilla and the mandible. The result demonstrated that the pMARPE could be manufactured without the need for conventional impression or laboratory procedures and effectively expanded the palate of an adult patient with maxillary transverse deficiency.
Keywords	Bone-borne rapid maxillary expansion ; Maxillary transverse deficiency ; Personalised ; Mini-implants ; Medicine ; R
Subject code	670
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Pakistan Medical Association
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Degradable silk fibroin based piezoresistive sensor for wearable biomonitoring.

Pang, Chunlin / Li, Fei / Hu, Xiaorao / Meng, Keyu / Pan, Hong / Xiang, Yong

Discover nano

2024 Volume 19, Issue 1, Page(s) 55

Abstract: Degradable wearable electronics are attracting increasing attention to weaken or eliminate the negative effect of waste e-wastes and promote the development of medical implants without secondary post-treatment. Although various degradable materials have ... ...

Abstract	Degradable wearable electronics are attracting increasing attention to weaken or eliminate the negative effect of waste e-wastes and promote the development of medical implants without secondary post-treatment. Although various degradable materials have been explored for wearable electronics, the development of degradable wearable electronics with integrated characteristics of highly sensing performances and low-cost manufacture remains challenging. Herein, we developed a facile, low-cost, and environmentally friendly approach to fabricate a biocompatible and degradable silk fibroin based wearable electronics (SFWE) for on-body monitoring. A combination of rose petal templating and hollow carbon nanospheres endows as-fabricated SFWE with good sensitivity (5.63 kPa
Language	English
Publishing date	2024-03-25
Publishing country	Switzerland
Document type	Journal Article
ISSN	2731-9229
ISSN (online)	2731-9229
DOI	10.1186/s11671-024-04001-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-κB /NLRP3 pathway.

Xiang, Xiaosong / Hu, Yongxin / Song, Zhiqiang / Wang, Chunlin

Tissue & cell

2023 Volume 84, Page(s) 102184

Abstract: Periodontitis is characterized by periodontal destruction triggered by chronic inflammation. The optimal treatment for periodontitis is to improve the periodontal microenvironment, reduce inflammation and achieve periodontal regeneration. Recently, the ... ...

Abstract	Periodontitis is characterized by periodontal destruction triggered by chronic inflammation. The optimal treatment for periodontitis is to improve the periodontal microenvironment, reduce inflammation and achieve periodontal regeneration. Recently, the role of TRPM2 in inflammatory diseases has been reported. However, the function of TRPM2 in periodontal disease and the biological mechanism remain elusive. Therefore, this study aimed to identify the role and explore the underlying mechanisms of TRPM2 in periodontal disease. Here, we first identified the characterization of human periodontal ligament stem cells (PDLSCs). Oil Red O Staining and Alizarin Red mineralized matrix were used to evaluate the multi-differentiation capacity of cells. Flow cytometry was employed to detect MSC-specific surface markers of hPDLSCs. hPDLSCs were treated with 0, 5, 10 or 40 μg/mL of TNF-α for 72 h. Western blot assay were performed to examine the expression of Transient receptor potential cation channel, subfamily M, member 2 (TRPM2) in hPDLSCs. CCK8 and colony formation assays were used to detect the cell viability and proliferation of hPDLSCs, which revealed that TRPM2 knockdown promoted hPDLSCs proliferation. Then, ALP activity in hPDLSCs was detected by ALP activity detection kit. Next, the expression of ALP and Runx2 in hPDLSCs was detected by immunofluorescence staining. The result showed that TRPM2 knockdown promoted osteogenic differentiation and affected the genes expression of osteogenic. Finally, the expressions of p-p65, p65, p-IκBα, IκBα and NLRP3 in hPDLSCs were detected by western blot assay. Together, these results suggested that knockdown of TRPM2 accelerated osteogenic differentiation of hPDLSCs through mediating NF-κB /NLRP3 pathway.
MeSH term(s)	Humans ; NF-kappa B/metabolism ; Periodontal Ligament ; NF-KappaB Inhibitor alpha/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; TRPM Cation Channels/genetics ; TRPM Cation Channels/metabolism ; Osteogenesis/genetics ; Cell Differentiation/genetics ; Periodontitis/metabolism ; Inflammation/metabolism ; Periodontal Diseases/metabolism ; Stem Cells ; Cells, Cultured ; Cell Proliferation
Chemical Substances	NF-kappa B ; NF-KappaB Inhibitor alpha (139874-52-5) ; NLR Family, Pyrin Domain-Containing 3 Protein ; TRPM Cation Channels ; TRPM2 protein, human
Language	English
Publishing date	2023-07-26
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	204424-9
ISSN	1532-3072 ; 0040-8166
ISSN (online)	1532-3072
ISSN	0040-8166
DOI	10.1016/j.tice.2023.102184
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Article ; Online: Skeletal and dentoalveolar modifications in adults with different sagittal facial patterns after personalized miniscrew-assisted rapid palatal expansion: A prospective cone-beam computed tomography study.

Wang, Chunlin / Liu, Conghua / Mao, Qin / Zhou, Lishu / Xiang, Xiaosong

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

2023 Volume 164, Issue 6, Page(s) 843–854

Abstract: Introduction: This study aimed to compare the skeletal and dental modifications in adults with different sagittal facial patterns by a personalized miniscrew-assisted rapid palatal expander (pMARPE).: Methods: Forty subjects (aged 18-28 years; 15 ... ...

Abstract	Introduction: This study aimed to compare the skeletal and dental modifications in adults with different sagittal facial patterns by a personalized miniscrew-assisted rapid palatal expander (pMARPE). Methods: Forty subjects (aged 18-28 years; 15 females and 25 males) with maxillary transverse deficiency were assigned to 1 of 3 groups (Class I, II, and III relationship) on the basis of their sagittal facial patterns. Each patient was treated with an individually customized expander. A similar expansion protocol was used for all patients. Cone-beam computed tomography scans were obtained before and after expansion. One-way analysis of variance was used to analyze differences among 3 groups in skeletal, dentoalveolar, and periodontal changes (P <0.05). Results: The success rates of expansion were higher in patients with a Class I or II relationship than those with a Class III relationship. Patients with a Class I or II relationship had greater changes in the anterior nasal spine and maxillary basal bone widths. A more parallel sutural opening in the anteroposterior direction was seen in those with a Class II relationship. The tipping of the maxillary first molar increased, and the buccal alveolar bone thickness decreased in all groups after expansion, especially in patients with a Class III relationship. Conclusions: The pMARPE effectively split the midpalatal suture among adults. However, midpalatal suture expansion was more difficult, and there were more dentoalveolar side effects and fewer orthopedic effects in patients with a Class III relationship than in those with Class I or II relationships.
MeSH term(s)	Male ; Female ; Humans ; Adult ; Prospective Studies ; Palatal Expansion Technique ; Cone-Beam Computed Tomography/methods ; Palate/diagnostic imaging ; Face ; Maxilla/diagnostic imaging
Language	English
Publishing date	2023-08-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	356699-7
ISSN	1097-6752 ; 0889-5406 ; 0002-9416
ISSN (online)	1097-6752
ISSN	0889-5406 ; 0002-9416
DOI	10.1016/j.ajodo.2023.05.033
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Ul III Zs.73: Show issues

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Article ; Online: The Impact of Rural Land Right on Farmers’ Income in Underdeveloped Areas

Xiang Deng / Min Zhang / Chunlin Wan

Land, Vol 11, Iss 10, p

Evidence from Micro-Survey Data in Yunnan Province, China

2022 Volume 1780

Abstract: The rural land right has paved the way for the deepening of China’s agricultural land system, which is critical to the successful implementation of the rural revitalization plan in the new era. Based on the micro-survey data of farmers in Yunnan Province, ...

Abstract	The rural land right has paved the way for the deepening of China’s agricultural land system, which is critical to the successful implementation of the rural revitalization plan in the new era. Based on the micro-survey data of farmers in Yunnan Province, we use an OLS model to empirically test the impact of rural land rights on farmers’ income in underdeveloped areas, and we use a stepwise regression method to test the mechanism role of land transfer willingness and behavior in the rural land right on farmers’ income. Benchmark regression results show that the implementation of rural land rights policy significantly increased the total income of farmers, which mainly comes from farm income. Although the rural land right policy has no significant impact on farmers’ non-farm income, the sign of right coefficient is positive. Mechanism analysis shows that the rural land right can increase the income of farmers by encouraging them to transfer to land. It shows that the property right of land is clear, which makes it easier for land to transfer and trade, and farmers can achieve a certain degree of scale operation, thereby increasing income. Finally, it is suggested that future fiscal funding in impoverished regions be directed toward land transfer links and that accompanying rules and regulations adequately protect farmers’ land contract management rights.
Keywords	rural land right ; farmers’ income ; farm income ; nonfarm income ; land transfer ; Agriculture ; S
Subject code	910
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: SARS-CoV-2 pneumonia with subcutaneous emphysema, mediastinal emphysema, and pneumothorax: A case report.

Xiang, Chunlin / Wu, Gang

Medicine

2020 Volume 99, Issue 20, Page(s) e20208

Abstract: Introduction: Since the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has affected more than 1,000,000 population in the world. Subcutaneous emphysema and pneumothorax are uncommon complications of SARS-CoV-2 ... ...

Abstract	Introduction: Since the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has affected more than 1,000,000 population in the world. Subcutaneous emphysema and pneumothorax are uncommon complications of SARS-CoV-2 pneumonia. Herein, we describe a fatal case of SARS-CoV-2 pneumonia with subcutaneous emphysema and pneumothorax. Patient concerns: Subcutaneous emphysema was found in neck, bilateral chest walls, abdomen wall, groin area, and scrotum of a 67-year-old man. Extensive air-space opacities, subcutaneous emphysema and a small amount of pneumothorax were found in his chest X-ray scan. Echocardiography showed left ventricular enlargement with ejection fraction 20%. Diagnosis: This resident of Wuhan with laboratory-confirmed SARS-CoV-2 infection had chronic pulmonary and cardiac diseases. Liver dysfunction, myocardial injury, and coagulation disorder were suggested by laboratory findings. Pneumonia, subcutaneous emphysema, and pneumothorax were confirmed with chest X-ray. Heart failure was revealed by echocardiography. Interventions: He was transferred to intensive care unit, where invasive ventilation was used for him during the whole hospitalization. Prone position ventilation, vasoconstrictor, antibacteria, and antiviral therapy were given. Outcomes: He died on the twelfth day after admission. Conclusions: Subcutaneous emphysema and pneumothorax may occur in patients with SARS-CoV-2 pneumonia and chronic pulmonary disease. Chronic cardiac disease might be aggravated by SARS-CoV-2 infection, and develop heart failure.
MeSH term(s)	Aged ; Betacoronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/physiopathology ; Humans ; Male ; Mediastinal Emphysema/etiology ; Pneumothorax/etiology ; SARS-CoV-2 ; Subcutaneous Emphysema/etiology
Keywords	covid19
Language	English
Publishing date	2020-04-27
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000020208
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Association of serum uric acid with right cardiac chamber remodeling assessed by cardiovascular magnetic resonance feature tracking in patients with connective tissue disease.

Tang, Yuanyuan / Yang, Zhaoxia / Wen, Jinyang / Tang, Dazhong / Luo, Yi / Xiang, Chunlin / Huang, Lu / Xia, Liming

Frontiers in endocrinology

2024 Volume 15, Page(s) 1351197

Abstract: Background: Right cardiac chamber remodeling is widespread in patients with connective tissue disease (CTD). Serum uric acid (SUA) is considered a potential independent risk factor for cardiovascular disease, and elevated SUA levels are often observed ... ...

Abstract	Background: Right cardiac chamber remodeling is widespread in patients with connective tissue disease (CTD). Serum uric acid (SUA) is considered a potential independent risk factor for cardiovascular disease, and elevated SUA levels are often observed in patients with CTD. The correlation between SUA levels and right cardiac chamber remodeling remains unclear. This study investigated the association of SUA with right cardiac chamber remodeling as assessed by cardiac magnetic resonance feature-tracking (CMR-FT) in CTD patients. Methods and results: In this cross-sectional study, a total of 104 CTD patients and 52 age- and sex-matched controls were consecutively recruited. All individuals underwent CMR imaging, and their SUA levels were recorded. The patients were divided into three subgroups based on the tertiles of SUA level in the present study. CMR-FT was used to evaluate the right atrial (RA) longitudinal strain and strain rate parameters as well as right ventricular (RV) global systolic peak strain and strain rate in longitudinal and circumferential directions for each subject. Univariable and multivariable linear regression analyses were used to explore the association of SUA with RV and RA strain parameters. Compared with the controls, the CTD patients showed significantly higher SUA levels but a lower RV global circumferential strain (GCS) and RA phasic strain parameters (all Conclusion: SUA may be a potential risk factor of right cardiac chamber remodeling and is independently associated with impaired RA conduit strain and RV GCS in CTD patients.
MeSH term(s)	Humans ; Uric Acid ; Cross-Sectional Studies ; Magnetic Resonance Imaging, Cine/methods ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy
Chemical Substances	Uric Acid (268B43MJ25)
Language	English
Publishing date	2024-03-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2024.1351197
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: SDG26 Is Involved in Trichome Control in

Zeng, Jing / Yang, Lanpeng / Tian, Minyu / Xie, Xiang / Liu, Chunlin / Ruan, Ying

Plants (Basel, Switzerland)

2023 Volume 12, Issue 8

Abstract: Plant trichomes formed by specialized epidermal cells play a role in protecting plants from biotic and abiotic stresses and can also influence the economic and ornamental value of plant products. Therefore, further studies on the molecular mechanisms of ... ...

Abstract	Plant trichomes formed by specialized epidermal cells play a role in protecting plants from biotic and abiotic stresses and can also influence the economic and ornamental value of plant products. Therefore, further studies on the molecular mechanisms of plant trichome growth and development are important for understanding trichome formation and agricultural production. SET Domain Group 26 (SDG26) is a histone lysine methyltransferase. Currently, the molecular mechanism by which SDG26 regulates the growth and development of Arabidopsis leaf trichomes is still unclear. We found that the mutant of Arabidopsis (
Language	English
Publishing date	2023-04-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants12081651
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