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  1. Article ; Online: Complications of Treatment for Symptomatic Vitreous Floaters: A Review.

    Kakulavarapu, Srividya / Kiryakoza, Lauren / Sridhar, Jayanth

    International ophthalmology clinics

    2022  Volume 62, Issue 3, Page(s) 131–155

    MeSH term(s) Eye Diseases/surgery ; Humans ; Vitrectomy ; Vitreous Body/surgery
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0000000000000433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: SARS-CoV-2 vaccine candidates: A beginning of the end of COVID-19 pandemic- Editorial.

    Kakulavarapu, Srividya / Boneva, Dessy / Elkbuli, Adel

    Annals of medicine and surgery (2012)

    2021  Volume 62, Page(s) 460–462

    Abstract: All three vaccines have substantial efficacy in preventing symptomatic and severe Sars-CoV-2 infection.•Vaccine dissemination is important due to the rapid mutagenic nature of the virus and continuing decline in the health and economies around the world. ...

    Abstract •All three vaccines have substantial efficacy in preventing symptomatic and severe Sars-CoV-2 infection.•Vaccine dissemination is important due to the rapid mutagenic nature of the virus and continuing decline in the health and economies around the world.•Further attempts to achieve widespread access of the vaccine is vital for all preventative measures to be maximally successful.
    Language English
    Publishing date 2021-02-01
    Publishing country England
    Document type Editorial
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2021.01.098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: FACTORS ASSOCIATED WITH THE USE OF 360-DEGREE LASER RETINOPEXY DURING PRIMARY VITRECTOMY WITH OR WITHOUT SCLERAL BUCKLE FOR RHEGMATOGENOUS RETINAL DETACHMENT AND IMPACT ON SURGICAL OUTCOMES (PRO STUDY REPORT NUMBER 4).

    Wang, Jay C / Ryan, Edwin H / Ryan, Claire / Kakulavarapu, Srividya / Mardis, Patrick J / Rodriguez, Marianeli / Stefater, James A / Forbes, Nora J / Gupta, Omesh / Capone, Antonio / Emerson, Geoffrey G / Joseph, Daniel P / Eliott, Dean / Yonekawa, Yoshihiro

    Retina (Philadelphia, Pa.)

    2019  Volume 40, Issue 11, Page(s) 2070–2076

    Abstract: Purpose: To determine factors associated with 360-degree laser retinopexy (360LR) during primary pars plana vitrectomy ± scleral buckle for rhegmatogenous retinal detachment (RRD) and its impact on surgical outcomes.: Methods: This is a multicenter, ... ...

    Abstract Purpose: To determine factors associated with 360-degree laser retinopexy (360LR) during primary pars plana vitrectomy ± scleral buckle for rhegmatogenous retinal detachment (RRD) and its impact on surgical outcomes.
    Methods: This is a multicenter, retrospective, interventional study. Patients undergoing primary pars plana vitrectomy or primary pars plana vitrectomy + scleral buckle for noncomplex primary RRD in 2015 were evaluated. Primary outcomes were single surgery anatomical success (SSAS) and final anatomical success. Secondary outcomes included final logarithm of the minimum angle of resolution visual acuity, epiretinal membrane formation, cystoid macular edema development, and number of subsequent vitrectomies. Multivariate regressions were performed.
    Results: Two thousand two hundred and forty-eight surgeries by 61 surgeons were included; of which, 516 underwent 360LR. Younger age (P = 0.01), more retinal breaks (P = 0.01), more extensive RRD (P < 0.001), and surgeon ID (P < 0.001) were significantly associated with 360LR. No significant associations between 360LR and single surgery anatomical success (P = 0.44), epiretinal membrane formation (P = 0.14), cystoid macular edema development (P = 0.28), or number of subsequent vitrectomies (P = 0.41) were found. Controlling for case complexity, 360LR was significantly associated with lower final anatomical success (P < 0.001) and worse final logarithm of the minimum angle of resolution visual acuity (P < 0.001).
    Conclusion: Multiple factors influenced whether 360LR was performed during primary pars plana vitrectomy ± scleral buckle for RRD. However, 360LR was not associated with improved surgical outcomes, and in fact, it may be associated with poorer outcomes.
    MeSH term(s) Aged ; Drainage ; Endotamponade ; Epiretinal Membrane/physiopathology ; Female ; Humans ; Laser Therapy/methods ; Macular Edema/physiopathology ; Male ; Middle Aged ; Retinal Detachment/physiopathology ; Retinal Detachment/surgery ; Retrospective Studies ; Scleral Buckling ; Silicone Oils ; Treatment Outcome ; Visual Acuity/physiology ; Vitrectomy
    Chemical Substances Silicone Oils
    Language English
    Publishing date 2019-12-21
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000002728
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of contact versus non-contact wide-angle viewing systems on outcomes of primary retinal detachment repair (PRO study report number 5).

    Tieger, Marisa G / Rodriguez, Marianeli / Wang, Jay C / Obeid, Anthony / Ryan, Claire / Gao, Xinxiao / Kakulavarapu, Srividya / Mardis, Patrick J / Madhava, Malika L / Maloney, Sean M / Adika, Adam Z / Peddada, Krishi V / Sioufi, Kareem / Stefater, James A / Forbes, Nora J / Capone, Antonio / Emerson, Geoffrey G / Joseph, Daniel P / Regillo, Carl /
    Hsu, Jason / Gupta, Omesh / Eliott, Dean / Ryan, Edwin H / Yonekawa, Yoshihiro

    The British journal of ophthalmology

    2020  Volume 105, Issue 3, Page(s) 410–413

    Abstract: Background/aims: Vitrectomy to repair retinal detachment is often performed with either non-contact wide-angle viewing systems or wide-angle contact viewing systems. The purpose of this study is to assess whether the viewing system used is associated ... ...

    Abstract Background/aims: Vitrectomy to repair retinal detachment is often performed with either non-contact wide-angle viewing systems or wide-angle contact viewing systems. The purpose of this study is to assess whether the viewing system used is associated with any differences in surgical outcomes of vitrectomy for primary non-complex retinal detachment repair.
    Methods: This is a multicenter, interventional, retrospective, comparative study. Eyes that underwent non-complex primary retinal detachment repair by either pars plana vitrectomy (PPV) alone or in combination with scleral buckle/PPV in 2015 were evaluated. The viewing system at the time of the retinal detachment repair was identified and preoperative patient characteristics, intraoperative findings and postoperative outcomes were recorded.
    Results: A total of 2256 eyes were included in our analysis. Of those, 1893 surgeries used a non-contact viewing system, while 363 used a contact lens system. There was no statistically significant difference in single surgery anatomic success at 3 months (p=0.72), or final anatomic success (p=0.40). Average postoperative visual acuity for the contact-based cases was logMAR 0.345 (20/44 Snellen equivalent) compared with 0.475 (20/60 Snellen equivalent) for non-contact (p=0.001). After controlling for numerous confounding variables in multivariable analysis, viewing system choice was no longer statistically significant (p=0.097).
    Conclusion: There was no statistically significant difference in anatomic success achieved for primary retinal detachment repair when comparing non-contact viewing systems to contact lens systems. Postoperative visual acuity was better in the contact-based group but this was not statistically significant when confounding factors were controlled for.
    MeSH term(s) Contact Lenses ; Equipment Design ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Postoperative Period ; Retinal Detachment/diagnosis ; Retinal Detachment/surgery ; Retrospective Studies ; Scleral Buckling/instrumentation ; Surgery, Computer-Assisted/instrumentation ; Visual Acuity ; Vitrectomy/instrumentation
    Language English
    Publishing date 2020-05-14
    Publishing country England
    Document type Comparative Study ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 80078-8
    ISSN 1468-2079 ; 0007-1161
    ISSN (online) 1468-2079
    ISSN 0007-1161
    DOI 10.1136/bjophthalmol-2020-315948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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