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  1. Article: Dwa nieznane listy Jana Jonstona do elektora brandenburskiego Fryderyka Wilhelma.

    Koch, H T / Skrobacki, A

    Archiwum historii medycyny

    1983  Volume 46, Issue 3, Page(s) 385–390

    Title translation 2 unknown letters of Jan Jonston to elector of Brandenburg Frederick William.
    MeSH term(s) Famous Persons ; Germany ; History, 17th Century ; Humans ; Poland ; Schools, Medical/history ; Writing
    Language Polish
    Publishing date 1983
    Publishing country Poland
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 123483-3
    ISSN 0004-0762
    ISSN 0004-0762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 71: Show issues Location:
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  2. Book ; Online: Adaptation of rural livelihoods to structural and climatic changes in Western Mongolia

    Vargas Koch, Camilo / Beushausen, Wiebke / Gilli, Mengina / Schoening, Simon / Schreiner, Lukas / Zotschew, Jana

    an analysis of the development potentials of horticultural production and tourism as income sources in Khovd and Uvs Province

    (SLE publication series ; S282)

    2020  

    Author's details Camilo Vargas Koch, Wiebke Beushausen, Mengina Gilli, Simon Schoening, Lukas Schreiner, Jana Zotschew
    Series title SLE publication series ; S282
    SLE Publication Series
    Collection SLE Publication Series
    Keywords Mongolei ; Gartenbau ; Tourismus
    Subject Touristik ; Fremdenverkehr ; Hortikultur
    Language English
    Size 1 Online-Ressource (xxiii, 270 Seiten), Illustrationen, Diagramme
    Publisher SLE
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020702528
    ISBN 978-3-947621-13-2 ; 3-947621-13-2
    DOI 10.18452/21517
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Rural bioeconomies in Europe: Socio-ecological conflicts, marginalized people and practices

    Friedrich, Jonathan / Holz, Jana / Koch, Philip / Pungas, Lilian / Eversberg, Dennis / Zscheischler, Jana

    Gaia

    2023  Volume 32, Issue 2, Page(s) 219

    Language German ; English
    Document type Article
    ZDB-ID 1114994-2
    ISSN 0940-5550
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

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  4. Article ; Online: Le virus SARS-CoV-2 utilise différentes voies d’entrée pour infecter les cellules.

    Koch, Jana / Uckeley, Zina M / Lozach, Pierre-Yves

    Medecine sciences : M/S

    2022  Volume 38, Issue 5, Page(s) 419–422

    Title translation SARS-CoV-2 uses different entry routes to infect host cells.
    MeSH term(s) Angiotensin-Converting Enzyme 2 ; COVID-19 ; Humans ; SARS-CoV-2 ; Virus Internalization
    Chemical Substances Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Language French
    Publishing date 2022-05-24
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632733-3
    ISSN 1958-5381 ; 0767-0974
    ISSN (online) 1958-5381
    ISSN 0767-0974
    DOI 10.1051/medsci/2022048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset.

    Sommer, Jakob / Wozniak, Justyna / Schmitt, Judith / Koch, Jana / Stingl, Julia C / Just, Katja S

    Biomedicines

    2024  Volume 12, Issue 1

    Abstract: Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug-drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to compare ...

    Abstract Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug-drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to compare different approaches to assess the substrate properties of drugs for certain polymorphic CYP2 enzymes.
    Methods: A standardized manual method and an automatic method were developed and compared to assess the substrate properties for the metabolism of drugs by CYP2D6, 2C9, and 2C19. The automatic method used a matching approach to three freely available resources. We applied the manual and automatic methods to a large real-world dataset deriving from a prospective multicenter study collecting adverse drug reactions in emergency departments in Germany (ADRED).
    Results: In total, 23,878 medication entries relating to 895 different drugs were analyzed in the real-world dataset. The manual method was able to assess 12.2% (
    Conclusion: A closer look at different classifications between methods revealed that both methods are prone to error in different ways. While the automated method excels in time efficiency, completeness, and actuality, the manual method might be better able to identify CYP2 substrates with clinical relevance.
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12010161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Cochlea-implantierte Kinder in der Ergotherapie

    Koch, Katharina / Lakowski, Jana

    Handlungsempfehlung für die ergotherapeutische Praxis

    (Neue Reihe Ergotherapie : Reihe 2, Fachbereich Pädiatrie ; 9)

    2004  

    Author's details Katharina Koch und Jana Lakowski. [Deutscher Verband der Ergotherapeuten e.V.]
    Series title Neue Reihe Ergotherapie : Reihe 2, Fachbereich Pädiatrie ; 9
    Neue Reihe Ergotherapie
    Neue Reihe Ergotherapie ; Reihe 2, Fachbereich Pädiatrie
    Collection Neue Reihe Ergotherapie
    Neue Reihe Ergotherapie ; Reihe 2, Fachbereich Pädiatrie
    Keywords Kind ; Cochlear-Implantat ; Sonderpädagogik
    Subject Kindheit ; Kindesalter ; Kindschaft ; Kinder ; Behindertenpädagogik ; Kind ; Heilerziehung ; Heilpädagogik ; Orthopädagogik ; Rehabilitationspädagogik ; Rehabilitation ; Sondererziehung ; Kochlear-Implantat ; Cochlear Implant ; Cochlea-Implantat ; Cochleaimplantat ; CI
    Language German
    Size 62 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher Schulz-Kirchner
    Publishing place Idstein
    Publishing country Germany
    Document type Book
    HBZ-ID HT014001490
    ISBN 3-8248-0437-9 ; 978-3-8248-0437-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 1839 order for loan Magazin

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  7. Conference proceedings: Förderung des Chondroanabolismus durch gezielte Eliminierung seneszenter Chondrozyten mittels Dasatinib und Quercetin

    Maurer, Svenja / Kirsch, Valeria / Brenner, Rolf / Riegger-Koch, Jana

    2023  , Page(s) AB39–2921

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2023); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkou171
    Database German Medical Science

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  8. Article ; Online: Translation and emerging functions of non-coding RNAs in inflammation and immunity.

    Della Bella, Elena / Koch, Jana / Baerenfaller, Katja

    Allergy

    2022  Volume 77, Issue 7, Page(s) 2025–2037

    Abstract: Regulatory non-coding RNAs (ncRNAs) including small non-coding RNAs (sRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) have gained considerable attention in the last few years. This is mainly due to their condition- and tissue-specific ...

    Abstract Regulatory non-coding RNAs (ncRNAs) including small non-coding RNAs (sRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) have gained considerable attention in the last few years. This is mainly due to their condition- and tissue-specific expression and their various modes of action, which suggests them as promising biomarkers and therapeutic targets. One important mechanism of ncRNAs to regulate gene expression is through translation of short open reading frames (sORFs). These sORFs can be located in lncRNAs, in non-translated regions of mRNAs where upstream ORFs (uORFs) represent the majority, or in circRNAs. Regulation of their translation can function as a quick way to adapt protein production to changing cellular or environmental cues, and can either depend solely on the initiation and elongation of translation, or on the roles of the produced functional peptides. Due to the experimental challenges to pinpoint translation events and to detect the produced peptides, translational regulation through regulatory RNAs is not well studied yet. In the case of circRNAs, they have only recently started to be recognized as regulatory molecules instead of mere artifacts of RNA biosynthesis. Of the many roles described for regulatory ncRNAs, we will focus here on their regulation during inflammation and in immunity.
    MeSH term(s) Humans ; Inflammation/genetics ; Peptides ; Protein Biosynthesis ; RNA, Circular ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism
    Chemical Substances Peptides ; RNA, Circular ; RNA, Long Noncoding
    Language English
    Publishing date 2022-02-09
    Publishing country Denmark
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15234
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    Zs.MO 125: Show issues

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  9. Article ; Online: Correction: An adipokine feedback regulating diurnal food intake rhythms in mice.

    Tsang, Anthony H / Koch, Christiane E / Kiehn, Jana-Thabea / Schmidt, Cosima X / Oster, Henrik

    eLife

    2022  Volume 11

    Language English
    Publishing date 2022-12-14
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.85366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: SARS-CoV-2 variants as super cell fusers: cause or consequence of COVID-19 severity?

    Koch, Jana / Uckeley, Zina M / Lozach, Pierre-Yves

    The EMBO journal

    2021  Volume 40, Issue 24, Page(s) e110041

    Abstract: The most severe forms of coronavirus disease 2019 (COVID-19) are often associated with the presence of syncytia in the lungs resulting from cell-cell fusion mediated by the SARS-CoV-2 spike protein. In this issue, Rajah and colleagues show that the SARS- ... ...

    Abstract The most severe forms of coronavirus disease 2019 (COVID-19) are often associated with the presence of syncytia in the lungs resulting from cell-cell fusion mediated by the SARS-CoV-2 spike protein. In this issue, Rajah and colleagues show that the SARS-CoV-2 alpha, beta, and delta variants promote enhanced syncytia formation as compared to the original strain.
    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics
    Chemical Substances Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 586044-1
    ISSN 1460-2075 ; 0261-4189
    ISSN (online) 1460-2075
    ISSN 0261-4189
    DOI 10.15252/embj.2021110041
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