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  1. Article ; Online: SARS-CoV-2: A comprehensive review from pathogenicity of the virus to clinical consequences.

    Lotfi, Melika / Rezaei, Nima

    Journal of medical virology

    2020  Volume 92, Issue 10, Page(s) 1864–1874

    Abstract: Nowadays, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused novel coronavirus disease (COVID-19) pandemic, is the worldwide challenge. The virus is highly contagious, and clinical consequences were very divers. It is estimated ... ...

    Abstract Nowadays, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused novel coronavirus disease (COVID-19) pandemic, is the worldwide challenge. The virus is highly contagious, and clinical consequences were very divers. It is estimated that if no effective action is taken, COVID-19 could plague 90% of the world's population and kill over 40 million people. So, it is essential to understand the virus pathogenicity and follow the preventive methods to control the high morbidity and mortality rates. Meanwhile our current knowledge of COVID-19 is still limited, despite hard efforts of scientists and clinicians during last few months. In this review article, we have collected the latest data about characteristics, pathogenesis, clinical manifestations, and diagnostic methods of SARS-CoV-2.
    MeSH term(s) Adaptive Immunity ; Angiotensin-Converting Enzyme 2 ; COVID-19/mortality ; COVID-19/physiopathology ; Cytokine Release Syndrome/virology ; Humans ; Immunity, Innate ; Risk Factors ; SARS-CoV-2/pathogenicity
    Chemical Substances ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: CRISPR/Cas13: A potential therapeutic option of COVID-19.

    Lotfi, Melika / Rezaei, Nima

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2020  Volume 131, Page(s) 110738

    Abstract: The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high ... ...

    Abstract The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high mortality and morbidity rates all around the world. Although scientists are trying to discover novel therapies and develop and evaluate various previous treatments, at the time of writing this paper, there was no definite therapy and vaccine for COVID-19. So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options.
    MeSH term(s) Betacoronavirus/drug effects ; Betacoronavirus/genetics ; COVID-19 ; CRISPR-Associated Proteins/pharmacology ; CRISPR-Cas Systems ; Conserved Sequence ; Coronavirus Infections/drug therapy ; Coronavirus Infections/genetics ; Coronavirus Infections/therapy ; Gene Editing ; Genetic Therapy/methods ; Genome, Viral ; Humans ; Pandemics ; Pneumonia, Viral/genetics ; Pneumonia, Viral/therapy ; RNA, Guide, CRISPR-Cas Systems/genetics ; RNA, Viral/antagonists & inhibitors ; RNA, Viral/genetics ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances CRISPR-Associated Proteins ; RNA, Guide, CRISPR-Cas Systems ; RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-17
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2020.110738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.198: Show issues Location:
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  3. Article ; Online: CRISPR/Cas13

    Lotfi, Melika / Rezaei, Nima

    Biomedicine & Pharmacotherapy

    A potential therapeutic option of COVID-19

    2020  Volume 131, Page(s) 110738

    Keywords Pharmacology ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2020.110738
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.198: Show issues Location:
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  4. Article ; Online: SARS‐CoV‐2

    Lotfi, Melika / Rezaei, Nima

    Journal of Medical Virology

    A comprehensive review from pathogenicity of the virus to clinical consequences

    2020  Volume 92, Issue 10, Page(s) 1864–1874

    Keywords Virology ; Infectious Diseases ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26123
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: CRISPR/Cas13: A potential therapeutic option of COVID-19

    Lotfi, Melika / Rezaei, Nima

    Biomed Pharmacother

    Abstract: The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high ... ...

    Abstract The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high mortality and morbidity rates all around the world. Although scientists are trying to discover novel therapies and develop and evaluate various previous treatments, at the time of writing this paper, there was no definite therapy and vaccine for COVID-19. So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #773856
    Database COVID19

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  6. Article ; Online: COVID-19: Transmission, prevention, and potential therapeutic opportunities.

    Lotfi, Melika / Hamblin, Michael R / Rezaei, Nima

    Clinica chimica acta; international journal of clinical chemistry

    2020  Volume 508, Page(s) 254–266

    Abstract: The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have ... ...

    Abstract The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have eluded investigators. Therefore, infection prevention, early viral detection and identification of successful treatment protocols provide the best approach in controlling disease spread. In this review, current therapeutic options, preventive methods and transmission routes of COVID-19 are discussed.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/pathogenicity ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/therapy ; COVID-19/transmission ; COVID-19 Vaccines ; Clinical Trials as Topic ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Drug Repositioning ; Humans ; Immunization, Passive/methods ; Immunologic Factors/therapeutic use ; Molecular Targeted Therapy/methods ; Pandemics/prevention & control ; Personal Protective Equipment ; Physical Distancing ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Viral Vaccines/biosynthesis ; COVID-19 Serotherapy
    Chemical Substances Adrenal Cortex Hormones ; Antiviral Agents ; COVID-19 Vaccines ; Immunologic Factors ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 80228-1
    ISSN 1873-3492 ; 0009-8981
    ISSN (online) 1873-3492
    ISSN 0009-8981
    DOI 10.1016/j.cca.2020.05.044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.173: Show issues Location:
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  7. Article: SARS-CoV-2: A comprehensive review from pathogenicity of the virus to clinical consequences

    Lotfi, Melika / Rezaei, Nima

    J. med. virol

    Abstract: Nowadays, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused novel coronavirus disease (COVID-19) pandemic, is the worldwide challenge. The virus is highly contagious, and clinical consequences were very divers. It is estimated ... ...

    Abstract Nowadays, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused novel coronavirus disease (COVID-19) pandemic, is the worldwide challenge. The virus is highly contagious, and clinical consequences were very divers. It is estimated that if no effective action is taken, COVID-19 could plague 90% of the world's population and kill over 40 million people. So, it is essential to understand the virus pathogenicity and follow the preventive methods to control the high morbidity and mortality rates. Meanwhile our current knowledge of COVID-19 is still limited, despite hard efforts of scientists and clinicians during last few months. In this review article, we have collected the latest data about characteristics, pathogenesis, clinical manifestations, and diagnostic methods of SARS-CoV-2.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #506044
    Database COVID19

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  8. Article ; Online: COVID-19

    Lotfi, Melika / Hamblin, Michael R. / Rezaei, Nima

    Clinica Chimica Acta

    Transmission, prevention, and potential therapeutic opportunities

    2020  Volume 508, Page(s) 254–266

    Keywords Clinical Biochemistry ; Biochemistry ; Biochemistry, medical ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80228-1
    ISSN 1873-3492 ; 0009-8981
    ISSN (online) 1873-3492
    ISSN 0009-8981
    DOI 10.1016/j.cca.2020.05.044
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.173: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article: COVID-19: Transmission, prevention, and potential therapeutic opportunities

    Lotfi, Melika / Hamblin, Michael R / Rezaei, Nima

    Clin Chim Acta

    Abstract: The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have ... ...

    Abstract The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense research efforts worldwide, an effective vaccine and viable treatment options have eluded investigators. Therefore, infection prevention, early viral detection and identification of successful treatment protocols provide the best approach in controlling disease spread. In this review, current therapeutic options, preventive methods and transmission routes of COVID-19 are discussed.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #448122
    Database COVID19

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  10. Article ; Online: Country Quarantine During COVID-19: Critical or Not?

    Samieefar, Noosha / Yari Boroujeni, Reza / Jamee, Mahnaz / Lotfi, Melika / Golabchi, Mohammad Rasul / Afshar, Alireza / Miri, Hamidreza / Khazeei Tabari, Mohammad Amin / Darzi, Pouya / Abdullatif Khafaie, Morteza / Amirheidari, Bagher / Tamadon, Amin / Rambod Rad, Niloofar / Samimi, Nastaran / Farjam, Mojtaba / Shiravi, Fatemeh / Farshidi, Narges / Hedayati Ch, Mojtaba / Doostkamel, Donya /
    Alikhani, Radin / Razmkhah, Mahboobeh / Abdollahifard, Saeed / Nasiri Kalmarzi, Rasoul / Kelishadi, Roya / Khazaei, Hosseinali / Aghamohammadi, Asghar / Jafari Mousavi, Farzaneh S / Shamsizadeh, Morteza / Khojasteh, Arash / Rezaei, Nima

    Disaster medicine and public health preparedness

    2020  Volume 15, Issue 4, Page(s) e24–e25

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Humans ; Quarantine
    Keywords covid19
    Language English
    Publishing date 2020-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2375268-3
    ISSN 1938-744X ; 1935-7893
    ISSN (online) 1938-744X
    ISSN 1935-7893
    DOI 10.1017/dmp.2020.384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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