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  1. Article: Urinary tract infections: Can we prevent uropathogenic

    Scribano, Daniela / Sarshar, Meysam / Fettucciari, Luana / Ambrosi, Cecilia

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2021  Volume 91, Issue 5-6, Page(s) 391–395

    Abstract: Urinary tract infections (UTIs) are among the most common causes of infections in women. Via the fecal-perineal-urethral route, ... ...

    Abstract Urinary tract infections (UTIs) are among the most common causes of infections in women. Via the fecal-perineal-urethral route, uropathogenic
    MeSH term(s) Anti-Bacterial Agents ; Escherichia coli Infections/prevention & control ; Female ; Humans ; Urinary Bladder ; Urinary Tract Infections/prevention & control ; Uropathogenic Escherichia coli
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-04-21
    Publishing country Switzerland
    Document type News
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Identifying Synthetic Faces through GAN Inversion and Biometric Traits Analysis

    Cecilia Pasquini / Francesco Laiti / Davide Lobba / Giovanni Ambrosi / Giulia Boato / Francesco De Natale

    Applied Sciences, Vol 13, Iss 816, p

    2023  Volume 816

    Abstract: In the field of image forensics, notable attention has been recently paid toward the detection of synthetic contents created through Generative Adversarial Networks (GANs), especially face images. This work explores a classification methodology inspired ... ...

    Abstract In the field of image forensics, notable attention has been recently paid toward the detection of synthetic contents created through Generative Adversarial Networks (GANs), especially face images. This work explores a classification methodology inspired by the inner architecture of typical GANs, where vectors in a low-dimensional latent space are transformed by the generator into meaningful high-dimensional images. In particular, the proposed detector exploits the inversion of the GAN synthesis process: given a face image under investigation, we identify the point in the GAN latent space which more closely reconstructs it; we project the vector back into the image space, and we compare the resulting image with the actual one. Through experimental tests on widely known datasets (including FFHQ, CelebA, LFW, and Caltech), we demonstrate that real faces can be accurately discriminated from GAN-generated ones by properly capturing the facial traits through different feature representations. In particular, features based on facial landmarks fed to a Support Vector Machine consistently yield a global accuracy of above 88% for each dataset. Furthermore, we experimentally prove that the proposed detector is robust concerning routinely applied post-processing operations.
    Keywords Generative Adversarial Networks ; image forensics ; GAN inversion ; face biometrics ; StyleGAN2 ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 006
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Acinetobacter baumannii

    Sarshar, Meysam / Behzadi, Payam / Scribano, Daniela / Palamara, Anna Teresa / Ambrosi, Cecilia

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 4

    Abstract: Acinetobacter ... ...

    Abstract Acinetobacter baumannii
    Language English
    Publishing date 2021-03-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10040387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: Current perspectives on

    Behzadi, Payam / Ambrosi, Cecilia / Scribano, Daniela / Zanetti, Stefania / Sarshar, Meysam / Gajdács, Márió / Donadu, Matthew Gavino

    Frontiers in microbiology

    2022  Volume 13, Page(s) 975616

    Language English
    Publishing date 2022-07-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.975616
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  5. Article ; Online: Adaptive strategies of uropathogenic Escherichia coli CFT073: from growth in lab media to virulence during host cell adhesion.

    Sarshar, Meysam / Scribano, Daniela / Limongi, Dolores / Zagaglia, Carlo / Palamara, Anna Teresa / Ambrosi, Cecilia

    International microbiology : the official journal of the Spanish Society for Microbiology

    2022  Volume 25, Issue 3, Page(s) 481–494

    Abstract: Urinary tract infections (UTIs) are a major concern in public health. The prevalent uropathogenic bacterium in healthcare settings is Escherichia coli. The increasing rate of antibiotic-resistant strains demands studies to understand E. coli pathogenesis ...

    Abstract Urinary tract infections (UTIs) are a major concern in public health. The prevalent uropathogenic bacterium in healthcare settings is Escherichia coli. The increasing rate of antibiotic-resistant strains demands studies to understand E. coli pathogenesis to drive the development of new therapeutic approaches. This study compared the gene expression profile of selected target genes in the prototype uropathogenic E. coli (UPEC) strain CFT073 grown in Luria Bertani (LB), artificial urine (AU), and during adhesion to host bladder cells by semi-quantitative real-time PCR (RT-PCR) assays. AU effectively supported the growth of strain CFT073 as well as other E. coli strains with different lifestyles, thereby confirming the appropriateness of this medium for in vitro models. Unexpectedly, gene expression of strain CFT073 in LB and AU was quite similar; conversely, during the adhesion assay, adhesins and porins were upregulated, while key global regulators were downregulated with respect to lab media. Interestingly, fimH and papGII genes were significantly expressed in all tested conditions. Taken together, these results provide for the first time insights of the metabolic and pathogenic profile of strain CFT073 during the essential phase of host cell adhesion.
    MeSH term(s) Cell Adhesion ; Escherichia coli Infections/microbiology ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Humans ; Uropathogenic Escherichia coli/genetics ; Uropathogenic Escherichia coli/metabolism ; Virulence/genetics
    Chemical Substances Escherichia coli Proteins
    Language English
    Publishing date 2022-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1454951-7
    ISSN 1618-1905 ; 1139-6709
    ISSN (online) 1618-1905
    ISSN 1139-6709
    DOI 10.1007/s10123-022-00235-y
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4964: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article: Inflammatory Response in Caco-2 Cells Stimulated with

    Bellini, Ilaria / Scribano, Daniela / Sarshar, Meysam / Ambrosi, Cecilia / Pizzarelli, Antonella / Palamara, Anna Teresa / D'Amelio, Stefano / Cavallero, Serena

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 10

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11101214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Insightful Improvement in the Design of Potent Uropathogenic

    Mousavifar, Leila / Sarshar, Meysam / Bridot, Clarisse / Scribano, Daniela / Ambrosi, Cecilia / Palamara, Anna Teresa / Vergoten, Gérard / Roubinet, Benoît / Landemarre, Ludovic / Bouckaert, Julie / Roy, René

    Pharmaceutics

    2023  Volume 15, Issue 2

    Abstract: Selective antiadhesion antagonists of ... ...

    Abstract Selective antiadhesion antagonists of Uropathogenic
    Language English
    Publishing date 2023-02-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15020527
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  8. Article: Gram-Negative Bacteria Holding Together in a Biofilm: The

    Pompilio, Arianna / Scribano, Daniela / Sarshar, Meysam / Di Bonaventura, Giovanni / Palamara, Anna Teresa / Ambrosi, Cecilia

    Microorganisms

    2021  Volume 9, Issue 7

    Abstract: Bacterial biofilms are a serious public-health problem worldwide. In recent years, the rates of antibiotic-resistant Gram-negative bacteria associated with biofilm-forming activity have increased worrisomely, particularly among healthcare-associated ... ...

    Abstract Bacterial biofilms are a serious public-health problem worldwide. In recent years, the rates of antibiotic-resistant Gram-negative bacteria associated with biofilm-forming activity have increased worrisomely, particularly among healthcare-associated pathogens.
    Language English
    Publishing date 2021-06-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9071353
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  9. Article: Acinetobacter baumannii Targets Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAMs) for Invasion of Pneumocytes.

    Ambrosi, Cecilia / Scribano, Daniela / Sarshar, Meysam / Zagaglia, Carlo / Singer, Bernhard B / Palamara, Anna Teresa

    mSystems

    2020  Volume 5, Issue 6

    Abstract: Multidrug- ... ...

    Abstract Multidrug-resistant
    Language English
    Publishing date 2020-12-22
    Publishing country United States
    Document type Journal Article
    ISSN 2379-5077
    ISSN 2379-5077
    DOI 10.1128/mSystems.00604-20
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  10. Article ; Online: The

    Perruzza, Lisa / Zagaglia, Carlo / Vitiello, Laura / Sarshar, Meysam / Strati, Francesco / Pasqua, Martina / Grassi, Fabio / Nicoletti, Mauro / Palamara, Anna Teresa / Ambrosi, Cecilia / Scribano, Daniela

    Microbiology spectrum

    2023  Volume 11, Issue 6, Page(s) e0077523

    Abstract: Importance: In this paper, we demonstrated that apyrase is released within the host cell cytoplasm during infection to target the intracellular ATP pool. By degrading intracellular ATP, apyrase contributes to prevent caspases activation, thereby ... ...

    Abstract Importance: In this paper, we demonstrated that apyrase is released within the host cell cytoplasm during infection to target the intracellular ATP pool. By degrading intracellular ATP, apyrase contributes to prevent caspases activation, thereby inhibiting the activation of pyroptosis in infected cells. Our results show, for the first time, that apyrase is involved in the modulation of host cell survival, thereby aiding this pathogen to dampen the inflammatory response. This work adds a further piece to the puzzle of
    MeSH term(s) Virulence Factors ; Bacterial Proteins ; Shigella flexneri ; Apyrase ; Eukaryotic Cells ; Adenosine Triphosphate
    Chemical Substances Virulence Factors ; Bacterial Proteins ; Apyrase (EC 3.6.1.5) ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.00775-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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