Article ; Online: Neurobrucellosis.
Current opinion in infectious diseases
2023 Volume 36, Issue 3, Page(s) 192–197
Abstract: Purpose of review: Brucellosis is one of the most common zoonosis worldwide, affecting 500 000 people, annually. Neurobrucellosis incidence is approximately 4%, and it is almost always heterogeneous. As there are no typical clinical features, its ... ...
| Abstract | Purpose of review: Brucellosis is one of the most common zoonosis worldwide, affecting 500 000 people, annually. Neurobrucellosis incidence is approximately 4%, and it is almost always heterogeneous. As there are no typical clinical features, its diagnosis is frequently misdiagnosing by other infections. Recent findings: Neurobrucellosis picture includes meningitis, meningoencephalitis, encephalitis, cranial neuropathies, intracranial hypertension, sinus thrombosis, hemorrhages radiculitis, peripheral neuropathy, myelitis, and psychiatric manifestations. The diagnosis should be based on symptoms and signs suggestive of neurobrucellosis, not explained by other neurological disease, cerebrospinal fluid analysis, a positive Brucella serology or culture, and a response to specific antibiotics, with a significant improvement of cerebrospinal fluid parameters. Summary: Neurobrucellosis can be insidious, and despite its global distribution, it is still unrecognized and frequently goes unreported. The understanding of the current epidemiology is necessary for eradication of the disease in humans, as well as the disease control in animals and prevention based on occupational hygiene and food hygiene. |
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| MeSH term(s) | Humans ; Anti-Bacterial Agents/therapeutic use ; Brucella ; Brucellosis/diagnosis ; Brucellosis/drug therapy ; Brucellosis/epidemiology ; Brucellosis/pathology ; Central Nervous System Bacterial Infections/diagnosis ; Central Nervous System Bacterial Infections/drug therapy ; Central Nervous System Bacterial Infections/microbiology ; Central Nervous System Bacterial Infections/pathology ; Meningitis/diagnosis |
| Chemical Substances | Anti-Bacterial Agents |
| Language | English |
| Publishing date | 2023-04-06 |
| Publishing country | United States |
| Document type | Review ; Journal Article |
| ZDB-ID | 645085-4 |
| ISSN | 1473-6527 ; 1535-3877 ; 0951-7375 ; 1355-834X |
| ISSN (online) | 1473-6527 ; 1535-3877 |
| ISSN | 0951-7375 ; 1355-834X |
| DOI | 10.1097/QCO.0000000000000920 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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