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  1. Article ; Online: Pre-phase transition of a Cu

    Zhang, Yan / He, Shaobo / Zhang, Qingxia / Zhang, Hongtao / Zhou, Jinchen / Yang, Xing / Wei, Qinhong / Chen, Lihui

    Nanoscale

    2024  Volume 16, Issue 3, Page(s) 1260–1271

    Abstract: Utilization of copper-deficient ... ...

    Abstract Utilization of copper-deficient Cu
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr05253b
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  2. Article: Exploration of stochastic dynamics and complexity in an epidemic system.

    He, Shaobo / Mukherjee, Sayan

    The European physical journal. Special topics

    2022  , Page(s) 1–7

    Abstract: We investigate the effect of noise in an epidemic system. We have studied dynamics and complexity for both the deterministic and its noise-induced model. We have verified the stochastic sensitivity under the variation of noise strength and changing the ... ...

    Abstract We investigate the effect of noise in an epidemic system. We have studied dynamics and complexity for both the deterministic and its noise-induced model. We have verified the stochastic sensitivity under the variation of noise strength and changing the initial conditions of the noise-induced system. It confirms that noise can make significant perturbation in the stochastic sensitivity. To quantify the dynamics, phase space analysis is done under both noisy and noise free conditions. The transition between regular and chaotic dynamics has been examined by
    Language English
    Publishing date 2022-08-29
    Publishing country France
    Document type Journal Article
    ZDB-ID 2267176-6
    ISSN 1951-6401 ; 1951-6355
    ISSN (online) 1951-6401
    ISSN 1951-6355
    DOI 10.1140/epjs/s11734-022-00658-8
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  3. Article: Kinetic

    Wang, Tao / Deng, Yinglei / Wang, Sidan / He, Jianfeng / Wang, Shaobo

    EJNMMI physics

    2024  Volume 11, Issue 1, Page(s) 20

    Abstract: Background: The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimation of hepatocellular carcinoma (HCC) via 18F-fluoro-2-deoxy-D-glucose PET/CT.: Methods: A dual-input four-compartment ...

    Abstract Background: The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimation of hepatocellular carcinoma (HCC) via 18F-fluoro-2-deoxy-D-glucose PET/CT.
    Methods: A dual-input four-compartment (4C) model, regarding endoplasmic reticulum was preliminarily used for kinetic estimation to differentiate 28 tumours from background liver tissue from 24 patients with HCC. Moreover, parameter images of the 4C model were generated from one patient with negative findings on conventional metabolic PET/CT.
    Results: Compared to the dual-input three-compartment (3C) model, the 4C model has better fitting quality, a close transport rate constant (K
    Conclusions: The 4C model with the endoplasmic reticulum performed better than the 3C model and produced additional useful parameters in kinetic estimation for differentiating HCC from background liver tissue.
    Language English
    Publishing date 2024-02-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2768912-8
    ISSN 2197-7364
    ISSN 2197-7364
    DOI 10.1186/s40658-024-00619-1
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  4. Article ; Online: Chaos and multi-layer attractors in asymmetric neural networks coupled with discrete fractional memristor.

    He, Shaobo / Vignesh, D / Rondoni, Lamberto / Banerjee, Santo

    Neural networks : the official journal of the International Neural Network Society

    2023  Volume 167, Page(s) 572–587

    Abstract: This article introduces a novel model of asymmetric neural networks combined with fractional difference memristors, which has both theoretical and practical implications in the rapidly evolving field of computational intelligence. The proposed model ... ...

    Abstract This article introduces a novel model of asymmetric neural networks combined with fractional difference memristors, which has both theoretical and practical implications in the rapidly evolving field of computational intelligence. The proposed model includes two types of fractional difference memristor elements: one with hyperbolic tangent memductance and the other with periodic memductance and memristor state described by sine functions. The authenticity of the constructed memristor is confirmed through fingerprint verification. The research extensively investigates the dynamics of a coupled neural network model, analyzing its stability at equilibrium states, studying bifurcation diagrams, and calculating the largest Lyapunov exponents. The results suggest that when incorporating sine memristors, the model demonstrates coexisting state variables depending on the initial conditions, revealing the emergence of multi-layer attractors. The article further demonstrates how the memristor state shifts through numerical simulations with varying memductance values. Notably, the study emphasizes the crucial role of memductance (synaptic weight) in determining the complex dynamical characteristics of neural network systems. To support the analytical results and demonstrate the chaotic response of state variables, the article includes appropriate numerical simulations. These simulations effectively validate the presented findings and provide concrete evidence of the system's chaotic behavior.
    MeSH term(s) Neural Networks, Computer
    Language English
    Publishing date 2023-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 740542-x
    ISSN 1879-2782 ; 0893-6080
    ISSN (online) 1879-2782
    ISSN 0893-6080
    DOI 10.1016/j.neunet.2023.08.041
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2365: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Integrated Circuit of a Chua's System Based on the Integral-Differential Nonlinear Resistance with Multi-Path Voltage-Controlled Oscillator.

    Duan, Zhikui / Li, Huosheng / He, Shaobo / Long, Yongxi / Yu, Xinmei / Ke, Qingqing

    Micromachines

    2024  Volume 15, Issue 3

    Abstract: In this paper, we present a fully integrated circuit without inductance implementing Chua's chaotic system. The circuit described in this study utilizes the SMIC 180 nm CMOS process and incorporates a multi-path voltage-controlled oscillator (VCO). The ... ...

    Abstract In this paper, we present a fully integrated circuit without inductance implementing Chua's chaotic system. The circuit described in this study utilizes the SMIC 180 nm CMOS process and incorporates a multi-path voltage-controlled oscillator (VCO). The integral-differential nonlinear resistance is utilized as a variable impedance component in the circuit, constructed using discrete devices from a microelectronics standpoint. Meanwhile, the utilization of a multi-path voltage-controlled oscillator ensures the provision of an adequate oscillation frequency and a stable waveform for the chaotic circuit. The analysis focuses on the intricate and dynamic behaviors exhibited by the chaotic microelectronic circuit. The experimental findings indicate that the oscillation frequency of the VCO can be adjusted within a range of 198 MHz to 320 MHz by manipulating the applied voltage from 0 V to 1.8 V. The circuit operates within a 1.8 V environment, and exhibits power consumption, gain-bandwidth product (GBW), area, and Lyapunov exponent values of 1.0782 mW, 4.43 GHz, 0.0165 mm
    Language English
    Publishing date 2024-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15030401
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  6. Article ; Online: Identification and anti-oxidative potential of milk fat globule membrane (MFGM)-derived bioactive peptides released through in vitro gastrointestinal digestion.

    Li, He / Guan, Kaifang / Liu, Min / Jiang, Wen / Yan, Fengjuan / Zhu, Aihua / Zhou, Shaobo

    Bioorganic chemistry

    2024  Volume 145, Page(s) 107232

    Abstract: This study investigated the stability of milk fat globule membrane (MFGM) protein under simulated gastrointestinal conditions using an in vitro enzymatic digestion method. The optimal hydrolysis conditions were determined by monitoring the changes in ... ...

    Abstract This study investigated the stability of milk fat globule membrane (MFGM) protein under simulated gastrointestinal conditions using an in vitro enzymatic digestion method. The optimal hydrolysis conditions were determined by monitoring the changes in particle size and zeta-potential of MFGM protein hydrolysates over time. Furthermore, the distribution of small molecular weight peptides with antioxidant activity was explored through DEAE-52 combined with in vitro cell experiments. Two novel antioxidant peptides (TGIIT and IITQ) were identified based on molecular docking technology and evaluated their potential scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-Azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS
    MeSH term(s) Kelch-Like ECH-Associated Protein 1 ; Antioxidants/pharmacology ; Molecular Docking Simulation ; NF-E2-Related Factor 2 ; Peptides/pharmacology ; Digestion ; Glycolipids ; Glycoproteins ; Lipid Droplets
    Chemical Substances milk fat globule ; Kelch-Like ECH-Associated Protein 1 ; Antioxidants ; NF-E2-Related Factor 2 ; Peptides ; Glycolipids ; Glycoproteins
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 120080-x
    ISSN 1090-2120 ; 0045-2068
    ISSN (online) 1090-2120
    ISSN 0045-2068
    DOI 10.1016/j.bioorg.2024.107232
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Syringaresinol attenuates Tau phosphorylation and ameliorates cognitive dysfunction induced by sevoflurane in aged rats.

    Zheng, Simin / Teng, Yunpeng / Liu, Hongtao / He, Jiaxuan / Zhang, Shaobo / Xiong, Hongfei

    Journal of neuropathology and experimental neurology

    2024  

    Abstract: Cognitive dysfunction following anesthesia with agents such as sevoflurane is a significant clinical problem, particularly in elderly patients. This study aimed to explore the protective effects of the phytochemical syringaresinol (SYR) against ... ...

    Abstract Cognitive dysfunction following anesthesia with agents such as sevoflurane is a significant clinical problem, particularly in elderly patients. This study aimed to explore the protective effects of the phytochemical syringaresinol (SYR) against sevoflurane-induced cognitive deficits in aged Sprague-Dawley rats and to determine the underlying mechanisms involved. We assessed the impact of SYR on sevoflurane-induced cognitive impairment, glial activation, and neuronal apoptosis through behavioral tests (Morris water maze), immunofluorescence, Western blotting for key proteins involved in apoptosis and inflammation, and enzyme-linked immunosorbent assays for interleukin-1β, tumor necrosis factor-α, and interleukin-6. SYR treatment mitigated sevoflurane-induced cognitive decline, reduced microglial and astrocyte activation (decreased Iba-1 and GFAP expression), and countered neuronal apoptosis (reduced Bax, cleaved-caspase3, and cleaved-PARP expression). SYR also enhanced Sirtuin-1 (SIRT1) expression and reduced p-Tau phosphorylation; these effects were reversed by the SIRT1 inhibitor EX527. SYR exerts neuroprotective effects on sevoflurane-induced cognitive dysfunction by modulating glial activity, apoptotic signaling, and Tau phosphorylation through the SIRT1 pathway. These findings could inform clinical strategies to safeguard cognitive function in patients undergoing anesthesia.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 3088-0
    ISSN 1554-6578 ; 0022-3069
    ISSN (online) 1554-6578
    ISSN 0022-3069
    DOI 10.1093/jnen/nlae026
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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.134: Show issues Location:
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    Ui II Zs.194: Show issues Location:
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  8. Article: Effect of light intensity on celery growth and flavonoid synthesis.

    Qin, Yanmei / Liu, Xuanxuan / Li, Chunyan / Chu, Qianwen / Cheng, Shaobo / Su, Lihong / Shao, Dalong / Guo, Xin / He, Zhongqun / Zhou, Xiaoting

    Frontiers in plant science

    2024  Volume 14, Page(s) 1326218

    Abstract: Light is one of the important environmental factors affecting the growth and development of facility vegetables. In this experiment, we investigated the effects of different light intensities on the growth, nutritional quality and flavonoid accumulation ... ...

    Abstract Light is one of the important environmental factors affecting the growth and development of facility vegetables. In this experiment, we investigated the effects of different light intensities on the growth, nutritional quality and flavonoid accumulation of celery under hydroponic and full LED light conditions. Four light intensities of 40, 100, 200, or 300 µmol·m
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1326218
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  9. Article: Method Validation and Measurement Uncertainty (MU) Evaluation on Enrofloxacin and Ciprofloxacin in the Aquatic Products.

    Liu, Li / Long, Nanbiao / Zhou, Juan / Liu, Manxue / He, Shaobo / Chu, Wuying

    International journal of analytical chemistry

    2023  Volume 2023, Page(s) 5554877

    Abstract: This study aimed to investigate a detection method of enrofloxacin and ciprofloxacin to be avail for strictly supervising the quality and safety of aquatic products. The results displayed that the optimal extraction conditions for enrofloxacin and ... ...

    Abstract This study aimed to investigate a detection method of enrofloxacin and ciprofloxacin to be avail for strictly supervising the quality and safety of aquatic products. The results displayed that the optimal extraction conditions for enrofloxacin and ciprofloxacin were the following five aspects: 15 g dosages of Na
    Language English
    Publishing date 2023-11-04
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2494714-3
    ISSN 1687-8779 ; 1687-8760
    ISSN (online) 1687-8779
    ISSN 1687-8760
    DOI 10.1155/2023/5554877
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  10. Article ; Online: Advanced Biomaterials for Cell‐Specific Modulation and Restore of Cancer Immunotherapy

    Shaobo Ruan / Yuanyu Huang / Mei He / Huile Gao

    Advanced Science, Vol 9, Iss 16, Pp n/a-n/a (2022)

    2022  

    Abstract: Abstract The past decade has witnessed the explosive development of cancer immunotherapies. Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target side effects remain to be the major limitations for broad ... ...

    Abstract Abstract The past decade has witnessed the explosive development of cancer immunotherapies. Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target side effects remain to be the major limitations for broad implementation of cancer immunotherapies to patient bedside. Encouragingly, advanced biomaterials offering cell‐specific modulation of immunological cues bring new solutions for improving the therapeutic efficacy while relieving side effect risks. In this review, focus is given on how functional biomaterials can enable cell‐specific modulation of cancer immunotherapy within the cancer‐immune cycle, with particular emphasis on antigen‐presenting cells (APCs), T cells, and tumor microenvironment (TME)‐resident cells. By reviewing the current progress in biomaterial‐based cancer immunotherapy, here the aim is to provide a better understanding of biomaterials’ role in targeting modulation of antitumor immunity step‐by‐step and guidelines for rationally developing targeting biomaterials for more personalized cancer immunotherapy. Moreover, the current challenge and future perspective regarding the potential application and clinical translation will also be discussed.
    Keywords biomaterials ; cancer immunotherapy ; drug delivery ; targeting modulation ; vaccines ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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