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  1. Article ; Online: From M

    Cesari, Cristiana / Berti, Beatrice / Bortoluzzi, Marco / Femoni, Cristina / Funaioli, Tiziana / Vivaldi, Federico Maria / Iapalucci, Maria Carmela / Zacchini, Stefano

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 12, Page(s) 3623–3642

    Abstract: Heterometallic Chini-type clusters [ ... ...

    Abstract Heterometallic Chini-type clusters [Pt
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d2dt03607j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Retrospektive multiparametrische Analyse des Leberparenchyms im MRT

    Adelmann, Beatrice Chantal

    2020  

    Institution Goethe-Universität Frankfurt am Main
    Author's details vorgelegt von Beatrice Chantal Adelmann aus Offenbach am Main
    Language German
    Size 110 Seiten, Illustrationen, Diagramme, 21 cm
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2021
    Note Zusammenfassung auf Deutsch und Englisch ; Literaturverzeichnis: Seite 91-102
    HBZ-ID HT020931905
    Database Catalogue ZB MED Medicine, Health

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    2021 D 319 order for loan Magazin

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  3. Book ; Thesis: IGF-1-Integrin-Interaktion bei Prostatakarzinomzellen in vitro

    Siech, Carolin

    2022  

    Institution Goethe-Universität Frankfurt am Main
    Author's details vorgelegt von Carolin Beatrice Siech aus Frankfurt am Main
    Language German ; English
    Size 57 Seiten, Illustrationen, Diagramme, 30 cm
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2022
    Note Zusammenfassung auf Deutsch und Englisch ; Literaturverzeichnis: Seite 45-49. - Enthält 1 Sonderabdruck
    HBZ-ID HT021565838
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Parcours médical et juridique transidentitaire - Le point de vue des personnes transgenres sur les avancées et les progrès attendus.

    Denaes, Béatrice

    Medecine sciences : M/S

    2023  Volume 39, Issue 1, Page(s) 53–57

    Abstract: In France, transidentity is no longer considered a "mental disorder" since 2010. For the WHO, it took until 2022. France is also one of the few countries to take care of almost the entire transition pathway. However, this pretty tree hides a jungle of ... ...

    Title translation Transidentity medical and legal courses: The viewpoint of transgender people on the advances and expected progress.
    Abstract In France, transidentity is no longer considered a "mental disorder" since 2010. For the WHO, it took until 2022. France is also one of the few countries to take care of almost the entire transition pathway. However, this pretty tree hides a jungle of obsolete texts and coding, discrimination in care, administrative and psychiatric constraints, transphobic rejections… Officially, the only recommendations regarding the medical history of transgender people date from 1989. Thirty-four years later, the High Authority for Health (HAS) is undertaking a profound overhaul of the recommendations made to doctors and associations concerned with the health of trans people.
    MeSH term(s) Humans ; Transgender Persons/psychology ; Transsexualism ; Physicians ; Mental Disorders ; France
    Language French
    Publishing date 2023-01-24
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 632733-3
    ISSN 1958-5381 ; 0767-0974
    ISSN (online) 1958-5381
    ISSN 0767-0974
    DOI 10.1051/medsci/2022199
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  5. Article ; Online: Erratum to 'Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study' (Br J Anaesth 2024; 132: 811-4).

    Roth, Sebastian / M'Pembele, René / Nienhaus, Johannes / Mauermann, Eckhard / Ionescu, Daniela / Szczeklik, Wojciech / De Hert, Stefan / Filipovic, Miodrag / Beck-Schimmer, Beatrice / Spadaro, Savino / Matute, Purificación / Bolliger, Daniel / Turhan, Sanem C / van Waes, Judith / Lagarto, Filipa / Theodoraki, Kassiani / Gupta, Anil / Gillmann, Hans-Jörg / Guzzetti, Luca /
    Kotfis, Katarzyna / Wulf, Hinnerk / Larmann, Jan / Corneci, Dan / Chammartin, Frédérique / Howell, Simon J / Buse, Giovanna L

    British journal of anaesthesia

    2024  

    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Published Erratum
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2024.03.002
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  6. Article ; Online: Corrigendum to "Tick-borne encephalitis: Acute clinical manifestations and severity in 581 cases from Germany, 2018-2020" [J Infect 86 (2023) 369-375].

    Nygren, Teresa M / Pilic, Antonia / Böhmer, Merle M / Wagner-Wiening, Christiane / Went, Simone-Beatrice / Wichmann, Ole / Hellenbrand, Wiebke

    The Journal of infection

    2024  Volume 88, Issue 2, Page(s) 218

    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Published Erratum
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2024.01.007
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  7. Article ; Online: Detection of CTX-M-15 ESBL in XDR Haemophilus parainfluenzae from a urethral swab.

    Caméléna, François / Merimèche, Manel / Liberge, Mathilde / Maubaret, Clara / Donay, Jean-Luc / Taha, Muhamed-Kheir / Fouéré, Sébastien / Berçot, Béatrice

    The Journal of antimicrobial chemotherapy

    2024  Volume 79, Issue 3, Page(s) 539–545

    Abstract: ... particularly worrisome, especially since the recent description of CTX-M-15 ESBL-producing isolates in Spain ... The aim of this study was to characterize a CTX-M-15-producing H. parainfluenzae clinical isolate, HP01 ... Oxford Nanopore sequencing to investigate the genetic environment of blaCTX-M-15. Phylogenetic analysis ...

    Abstract Objectives: Haemophilus parainfluenzae is an opportunistic pathogen causing respiratory tract infection and sexually transmitted diseases. The emergence of multidrug resistance in this species is particularly worrisome, especially since the recent description of CTX-M-15 ESBL-producing isolates in Spain. The aim of this study was to characterize a CTX-M-15-producing H. parainfluenzae clinical isolate, HP01, obtained from a urethral swab.
    Methods: MICs were determined with gradient strips for this isolate. Hydrolysis assays were performed with the β LACTA test. Genomic DNA from HP01 was subjected to Illumina and Oxford Nanopore sequencing to investigate the genetic environment of blaCTX-M-15. Phylogenetic analysis was performed with available H. parainfluenzae genomes from the NCBI database, including CTX-M-15 producers.
    Results: HP01, an XDR isolate, was resistant to penicillin, third-generation cephalosporins, fluoroquinolones, macrolides, cyclines and co-trimoxazole and susceptible only to carbapenems and rifampicin. HP01 carried blaTEM-1, blaCTX-M-15, tet(M), catS and mef(E)/mel and harboured amino acid substitutions in PBP3, PBP5, GyrA, ParC and FolA implicated in resistance. Genomic analysis revealed that blaCTX-M-15 was carried by a Tn3-like transposon inserted into a novel integrative and conjugative element (ICE), ICEHpaSLS, present on the chromosome and belonging to the ICEHin1056 family described in Haemophilus influenzae. The tet(M)-MEGA element was also detected on the chromosome. No plasmid was found. The phylogenetic analysis showed that four H. parainfluenzae producing CTX-M-15 clustered in the same clade.
    Conclusions: Here we report the description of an XDR H. parainfluenzae producing blaCTX-M-15 isolated from a urethral swab. The blaCTX-M-15 gene was inserted into an ICE structure similar to those recently described in CTX-M-15 producers in Spain. The emergence of XDR H. parainfluenzae producing blaCTX-M-15 is a matter of great concern. Careful surveillance is required to prevent its spread.
    MeSH term(s) Haemophilus parainfluenzae/genetics ; Phylogeny ; Anti-Bacterial Agents/pharmacology ; Amino Acid Substitution ; beta-Lactamases/genetics
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkad408
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    Zs.A 1197: Show issues Location:
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    Zs.MO 124: Show issues

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  8. Article ; Online: SARS-CoV-2S-Protein-Ace2 Binding Analysis Using Surface Plasmon Resonance.

    Baardsnes, Jason / Paul-Roc, Béatrice

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2762, Page(s) 71–87

    Abstract: Surface plasmon resonance (SPR) allows for the label-free determination of the binding affinity and rate constants of bimolecular interactions. Here, we describe the method used for the analysis of the Ace2-SARS-CoV2 S-protein interaction using indirect ... ...

    Abstract Surface plasmon resonance (SPR) allows for the label-free determination of the binding affinity and rate constants of bimolecular interactions. Here, we describe the method used for the analysis of the Ace2-SARS-CoV2 S-protein interaction using indirect capture of the S-protein onto the SPR surface, and flowing monomeric Ace2. This method will allow for the determination of the rate constants for affinity, with additional analysis that is achievable using S-protein capture levels in conjunction with the sensorgram response for relative activity benchmarking.
    MeSH term(s) Humans ; Surface Plasmon Resonance/methods ; SARS-CoV-2/metabolism ; RNA, Viral/metabolism ; COVID-19 ; Protein Binding ; Spike Glycoprotein, Coronavirus/metabolism
    Chemical Substances RNA, Viral ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3666-4_5
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  9. Book ; Online: CLASS-M

    Zhang, Bodong / Manoochehri, Hamid / Ho, Man Minh / Fooladgar, Fahimeh / Chong, Yosep / Knudsen, Beatrice S. / Sirohi, Deepika / Tasdizen, Tolga

    Adaptive stain separation-based contrastive learning with pseudo-labeling for histopathological image classification

    2023  

    Abstract: ... supervised patch-level histopathological image classification model, named CLASS-M, that does not require ... extensively labeled datasets. CLASS-M is formed by two main parts: a contrastive learning module that uses ... clear cell renal cell carcinoma datasets. We demonstrate that our CLASS-M model has the best performance on both datasets ...

    Abstract Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However, patch-level classification is preferable in applications where only a limited number of cases are available or when local prediction accuracy is critical. On the other hand, acquiring extensive datasets with localized labels for training is not feasible. In this paper, we propose a semi-supervised patch-level histopathological image classification model, named CLASS-M, that does not require extensively labeled datasets. CLASS-M is formed by two main parts: a contrastive learning module that uses separated Hematoxylin and Eosin images generated through an adaptive stain separation process, and a module with pseudo-labels using MixUp. We compare our model with other state-of-the-art models on two clear cell renal cell carcinoma datasets. We demonstrate that our CLASS-M model has the best performance on both datasets. Our code is available at github.com/BzhangURU/Paper_CLASS-M/tree/main
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2023-12-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: The asymmetric J-curve phenomenon

    Moses Mutharime Mwito / Beatrice K. Mkenda / Eliab Luvanda

    Central Bank Review, Vol 21, Iss 1, Pp 25-

    Kenya versus her trading partners

    2021  Volume 34

    Abstract: This paper examines asymmetries in the J-curve effects of real exchange rate on Kenya’s ... reveal J-curve effects in only 7 bilateral trade relations. However, when the estimation is performed ... assuming asymmetric effects, the J-curve effects are evident in 13 cases. Long-run and short-run ...

    Abstract This paper examines asymmetries in the J-curve effects of real exchange rate on Kenya’s trade balance by using panel data for bilateral trade with 30 trading partners. The data covers the period from 2006q1 to 2018q4 and the Pooled Mean Group (PMG) estimation technique, under both the linear and nonlinear ARDL frameworks, is applied. This paper departs from previous studies by using a modified version of the standard trade balance model, which is more suited for bilateral trade analyses, and by incorporating nonlinearities. The findings of the PMG estimation based on the assumption of symmetric exchange rate effects reveal J-curve effects in only 7 bilateral trade relations. However, when the estimation is performed assuming asymmetric effects, the J-curve effects are evident in 13 cases. Long-run and short-run asymmetries are also confirmed and it is established that a simultaneous bilateral real depreciation of the exchange rate boosts the long-run trade balance. The implication of these findings is that a devaluation policy can be used to raise competitiveness of Kenya’s exports in the long-run.
    Keywords Bilateral trade balances ; Exchange rate ; Asymmetric effects ; J-curve ; Kenya ; Panel data ; Finance ; HG1-9999 ; Banking ; HG1501-3550 ; Economics as a science ; HB71-74
    Subject code 381
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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