LIVIVO - Search results -

Search results

Result 1 - 10 of total 45

Search options

Article ; Online: Sexually dimorphic murine brain uptake of the 18 kDa translocator protein PET radiotracer [

Knyzeliene, Agne / Wimberley, Catriona / MacAskill, Mark G / Alcaide-Corral, Carlos J / Morgan, Timaeus E F / Henry, Martyn C / Lucatelli, Christophe / Pimlott, Sally L / Sutherland, Andrew / Tavares, Adriana A S

Brain communications

2024 Volume 6, Issue 1, Page(s) fcae008

Abstract: The 18 kDa translocator protein is a well-known biomarker of neuroinflammation, but also plays a role in homeostasis. PET with 18 kDa translocator protein radiotracers [ ...

Abstract	The 18 kDa translocator protein is a well-known biomarker of neuroinflammation, but also plays a role in homeostasis. PET with 18 kDa translocator protein radiotracers [
Language	English
Publishing date	2024-01-16
Publishing country	England
Document type	Journal Article
ISSN	2632-1297
ISSN (online)	2632-1297
DOI	10.1093/braincomms/fcae008
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Modelling [

MacAskill, Mark G / Wimberley, Catriona / Morgan, Timaeus E F / Alcaide-Corral, Carlos J / Newby, David E / Lucatelli, Christophe / Sutherland, Andrew / Pimlott, Sally L / Tavares, Adriana A S

European journal of nuclear medicine and molecular imaging

2021 Volume 49, Issue 1, Page(s) 137–145

Abstract: Purpose: To provide a comprehensive assessment of the novel 18 kDa translocator protein (TSPO) radiotracer, [: Methods: Naive adult rats and rats with surgically induced permanent coronary artery ligation received a bolus intravenous injection of [!## ...

Abstract	Purpose: To provide a comprehensive assessment of the novel 18 kDa translocator protein (TSPO) radiotracer, [ Methods: Naive adult rats and rats with surgically induced permanent coronary artery ligation received a bolus intravenous injection of [ Results: PET outcome measures estimated using IDIF significantly correlated with those derived with invasive AIF, albeit with an inherent systematic bias. Truncation of the dynamic PET scan duration to less than 100 min reduced the stability of the kinetic modelling outputs. Quantification of [ Conclusion: Modelling of [
MeSH term(s)	Algorithms ; Animals ; Brain/diagnostic imaging ; Brain/metabolism ; Carrier Proteins/metabolism ; Positron-Emission Tomography ; Radiopharmaceuticals ; Rats ; Receptors, GABA-A/metabolism
Chemical Substances	Carrier Proteins ; Radiopharmaceuticals ; Receptors, GABA-A ; Tspo protein, rat (141440-82-6)
Language	English
Publishing date	2021-08-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	8236-3
ISSN	1619-7089 ; 0340-6997 ; 1619-7070
ISSN (online)	1619-7089
ISSN	0340-6997 ; 1619-7070
DOI	10.1007/s00259-021-05482-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1227: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Investigation of the summer 2018 European ozone air pollution episodes using novel satellite data and modelling

R. J. Pope / B. J. Kerridge / M. P. Chipperfield / R. Siddans / B. G. Latter / L. J. Ventress / M. A. Pimlott / W. Feng / E. Comyn-Platt / G. D. Hayman / S. R. Arnold / A. M. Graham

Atmospheric Chemistry and Physics, Vol 23, Pp 13235-

2023 Volume 13253

Abstract: In the summer of 2018, Europe experienced an intense heatwave which coincided with several persistent large-scale ozone ( O 3 ) pollution episodes. Novel satellite data of lower-tropospheric column O 3 from the Global Ozone Monitoring Experiment-2 (GOME- ... ...

Abstract	In the summer of 2018, Europe experienced an intense heatwave which coincided with several persistent large-scale ozone ( O 3 ) pollution episodes. Novel satellite data of lower-tropospheric column O 3 from the Global Ozone Monitoring Experiment-2 (GOME-2) and Infrared Atmospheric Sounding Interferometer (IASI) on the MetOp satellite showed substantial enhancements in 2018 relative to other years since 2012. Surface observations also showed ozone enhancements across large regions of continental Europe in summer 2018 compared to 2017. Enhancements to surface temperature and the O 3 precursor gases carbon monoxide and methanol in 2018 were co-retrieved from MetOp observations by the same scheme. This analysis was supported by the TOMCAT chemistry transport model (CTM) to investigate processes driving the observed O 3 enhancements. Through several targeted sensitivity experiments we show that meteorological processes, and emissions to a secondary order, were important for controlling the elevated O 3 concentrations at the surface. However, mid-tropospheric ( ∼ 500 hPa ) O 3 enhancements were dominated by meteorological processes. We find that contributions from stratospheric O 3 intrusions ranged between 15 %–40 %. Analysis of back trajectories indicates that the import of O 3 -enriched air masses into Europe originated over the North Atlantic, substantially increasing O 3 in the 500 hPa layer during summer 2018.
Keywords	Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	511
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Investigating the global OH radical distribution using steady-state approximations and satellite data

M. A. Pimlott / R. J. Pope / B. J. Kerridge / B. G. Latter / D. S. Knappett / D. E. Heard / L. J. Ventress / R. Siddans / W. Feng / M. P. Chipperfield

Atmospheric Chemistry and Physics, Vol 22, Pp 10467-

2022 Volume 10488

Abstract: ... to the short lifetime of OH ( ∼1 s), SSAs of varying complexities can be used to model its concentration and ... complexities of the SSAs are representative of OH. In the case of a simplified SSA (S-SSA), where we have ... The same S-SSA is applied to aircraft measurements from the Atmospheric Tomography Mission (ATom) and ...

Abstract	We present a novel approach to derive indirect global information on the hydroxyl radical (OH), one of the most important atmospheric oxidants, using state-of-the-art satellite trace gas observations (key sinks and sources of OH) and a steady-state approximation (SSA). This is a timely study as OH observations are predominantly from spatially sparse field and infrequent aircraft campaigns, so there is a requirement for further approaches to infer spatial and temporal information on OH and its interactions with important climate (e.g. methane, CH 4 ) and air quality (e.g. nitrogen dioxide, NO 2 ) trace gases. Due to the short lifetime of OH ( ∼1 s), SSAs of varying complexities can be used to model its concentration and offer a tool to examine the OH budget in different regions of the atmosphere. Here, we use the well-evaluated TOMCAT three-dimensional chemistry transport model to identify atmospheric regions where different complexities of the SSAs are representative of OH. In the case of a simplified SSA (S-SSA), where we have observations of ozone (O 3 ) , carbon monoxide (CO), CH 4 and water vapour (H 2 O) from the Infrared Atmospheric Sounding Interferometer (IASI) on board ESA's MetOp-A satellite, it is most representative of OH between 600 and 700 hPa (though suitable between 400–800 hPa) within ∼20 %–30 % of TOMCAT modelled OH. The same S-SSA is applied to aircraft measurements from the Atmospheric Tomography Mission (ATom) and compares well with the observed OH concentrations within ∼26 %, yielding a correlation of 0.78. We apply the S-SSA to IASI data spanning 2008–2017 to explore the global long-term inter-annual variability of OH. Relative to the 10-year mean, we find that global annual mean OH anomalies ranged from −3.1 % to +4.7 %, with the largest spread in the tropics between −6.9 % and +7.7 %. Investigation of the individual terms in the S-SSA over this time period suggests that O 3 and CO were the key drivers of variability in the production and loss of OH. For example, large enhancement in the ...
Keywords	Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	333
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: SPECT imaging in dementia.

Pimlott, S L / Ebmeier, K P

The British journal of radiology

2007 Volume 80 Spec No 2, Page(s) S153–9

Abstract: Single photon emission computed tomography (SPECT) is a non-invasive functional neuroimaging technique that can be used in the diagnosis of dementia. This review describes some of the SPECT radiotracers available for imaging dementia patients and ... ...

Abstract	Single photon emission computed tomography (SPECT) is a non-invasive functional neuroimaging technique that can be used in the diagnosis of dementia. This review describes some of the SPECT radiotracers available for imaging dementia patients and discusses recommendations for the clinical use of this imaging technique.
MeSH term(s)	Dementia/diagnostic imaging ; Dementia/metabolism ; Humans ; Neurotransmitter Agents/metabolism ; Positron-Emission Tomography/methods ; Practice Guidelines as Topic ; Radiopharmaceuticals ; Tomography, Emission-Computed, Single-Photon/methods
Chemical Substances	Neurotransmitter Agents ; Radiopharmaceuticals
Language	English
Publishing date	2007-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr/89285735
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ue I Zs.11: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Brain-stem serotonin transporter availability in maternal uniparental disomy and deletion Prader-Willi syndrome.

Krishnadas, Rajeev / Cooper, Sally-Ann / Nicol, Alice / Pimlott, Sally / Soni, Sarita / Holland, Anthony J / McArthur, Laura / Cavanagh, Jonathan

The British journal of psychiatry : the journal of mental science

2018 Volume 212, Issue 1, Page(s) 57–58

Abstract: Prader-Willi syndrome (PWS) is a rare condition because of the deletion of paternal chromosomal material (del PWS), or a maternal uniparental disomy (mUPD PWS), at 15q11-13. Affective psychosis is more prevalent in mUPD PWS. We investigated the ... ...

Abstract	Prader-Willi syndrome (PWS) is a rare condition because of the deletion of paternal chromosomal material (del PWS), or a maternal uniparental disomy (mUPD PWS), at 15q11-13. Affective psychosis is more prevalent in mUPD PWS. We investigated the relationship between the two PWS genetic variants and brain-stem serotonin transporter (5-HTT) availability in adult humans. Mean brain-stem 5-HTT availability determined by [123I]-beta-CIT single photon emission tomography was lower in eight adults with mUPD PWS compared with nine adults with del PWS (mean difference -0.93, t = -2.85, P = 0.014). Our findings confirm an association between PWS genotype and brain-stem 5-HTT availability, implicating a maternally expressed/paternally imprinted gene, that is likely to account for the difference in psychiatric phenotypes between the PWS variants. Declaration of interest None.
MeSH term(s)	Adult ; Brain Stem/diagnostic imaging ; Brain Stem/metabolism ; Chromosome Deletion ; Chromosomes, Human, Pair 15/genetics ; Cross-Sectional Studies ; Female ; Humans ; Male ; Prader-Willi Syndrome/diagnostic imaging ; Prader-Willi Syndrome/genetics ; Prader-Willi Syndrome/metabolism ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Tomography, Emission-Computed, Single-Photon ; Uniparental Disomy/genetics ; Young Adult
Chemical Substances	SLC6A4 protein, human ; Serotonin Plasma Membrane Transport Proteins
Language	English
Publishing date	2018-02-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218103-4
ISSN	1472-1465 ; 0007-1250
ISSN (online)	1472-1465
ISSN	0007-1250
DOI	10.1192/bjp.2017.7
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui II Zs.5: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer.

MacAskill, Mark G / Walton, Tashfeen / Williams, Lewis / Morgan, Timaeus E F / Alcaide-Corral, Carlos José / Dweck, Marc R / Gray, Gillian A / Newby, David E / Lucatelli, Christophe / Sutherland, Andrew / Pimlott, Sally L / Tavares, Adriana A S

PloS one

2019 Volume 14, Issue 5, Page(s) e0217515

Abstract: Introduction: Positron Emission Tomography (PET) imaging with selective 18 kDa translocator protein (TSPO) radiotracers has contributed to our understanding on the role of inflammation in disease development and progression. With an increasing number of ...

Abstract	Introduction: Positron Emission Tomography (PET) imaging with selective 18 kDa translocator protein (TSPO) radiotracers has contributed to our understanding on the role of inflammation in disease development and progression. With an increasing number of rodent models of human disease and expansion of the preclinical PET imaging base worldwide, accurate quantification of longitudinal rodent TSPO PET datasets is necessary. This is particularly relevant as TSPO PET quantification relies on invasive blood sampling due to lack of a suitable tissue reference region. Here we investigate the kinetics and quantification bias of a novel TSPO radiotracer [18F]AB5186 in rats using automatic, manual and image derived input functions. Methods: [18F]AB5186 was administered intravenously and dynamic PET imaging was acquired over 2 hours. Arterial blood was collected manually to derive a population based input function or using an automatic blood sampler to derive a plasma input function. Manually sampled blood was also used to analyze the [18F]AB5186 radiometabolite profile in plasma and applied to all groups as a population based dataset. Kinetic models were used to estimate distribution volumes (VT) and [18F]AB5186 outcome measure bias was determined. Results: [18F]AB5186 distribution in rats was consistent with TSPO expression and at 2 h post-injection 50% of parent compound was still present in plasma. Population based manual sampling methods and image derived input function (IDIF) underestimated VT by ~50% and 88% compared with automatic blood sampling, respectively. The VT variability was lower when using IDIF versus arterial blood sampling methods and analysis of the Bland-Altman plots showed a good agreement between methods of analysis. Conclusion: Quantification of TSPO PET rodent data using image-derived methods, which are more amenable for longitudinal scanning of small animals, yields outcome measures with reduced variability and good agreement, albeit biased, compared with invasive blood sampling methods.
MeSH term(s)	Animals ; Carrier Proteins/antagonists & inhibitors ; Fluorine Radioisotopes ; Image Processing, Computer-Assisted ; Male ; Models, Animal ; Molecular Imaging/methods ; Positron-Emission Tomography/methods ; Radiopharmaceuticals/administration & dosage ; Radiopharmaceuticals/pharmacokinetics ; Rats ; Receptors, GABA-A
Chemical Substances	Carrier Proteins ; Fluorine Radioisotopes ; Radiopharmaceuticals ; Receptors, GABA-A ; Tspo protein, rat (141440-82-6) ; Fluorine-18 (GZ5I74KB8G)
Language	English
Publishing date	2019-05-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0217515
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Radiotracer properties determined by high performance liquid chromatography: a potential tool for brain radiotracer discovery.

Tavares, Adriana Alexandre S / Lewsey, James / Dewar, Deborah / Pimlott, Sally L

Nuclear medicine and biology

2012 Volume 39, Issue 1, Page(s) 127–135

Abstract: Introduction: Previously, development of novel brain radiotracers has largely relied on simple screening tools. Improved selection methods at the early stages of radiotracer discovery and an increased understanding of the relationships between in vitro ... ...

Abstract	Introduction: Previously, development of novel brain radiotracers has largely relied on simple screening tools. Improved selection methods at the early stages of radiotracer discovery and an increased understanding of the relationships between in vitro physicochemical and in vivo radiotracer properties are needed. We investigated if high performance liquid chromatography (HPLC) methodologies could provide criteria for lead candidate selection by comparing HPLC measurements with radiotracer properties in humans. Methods: Ten molecules, previously used as radiotracers in humans, were analysed to obtain the following measures: partition coefficient (Log P); permeability (P(m)); percentage of plasma protein binding (%PPB); and membrane partition coefficient (K(m)). Relationships between brain entry measurements (Log P, P(m) and %PPB) and in vivo brain percentage injected dose (%ID); and K(m) and specific binding in vivo (BP(ND)) were investigated. Log P values obtained using in silico packages and flask methods were compared with Log P values obtained using HPLC. Results: The modelled associations with %ID were stronger for %PPB (r(2)=0.65) and P(m) (r(2)=0.77) than for Log P (r(2)=0.47) while 86% of BP(ND) variance was explained by K(m). Log P values were variable dependant on the methodology used. Conclusions: Log P should not be relied upon as a predictor of blood-brain barrier penetration during brain radiotracer discovery. HPLC measurements of permeability, %PPB and membrane interactions may be potentially useful in predicting in vivo performance and hence allow evaluation and ranking of compound libraries for the selection of lead radiotracer candidates at early stages of radiotracer discovery.
MeSH term(s)	Blood Proteins/metabolism ; Blood-Brain Barrier/diagnostic imaging ; Blood-Brain Barrier/metabolism ; Brain/diagnostic imaging ; Brain/metabolism ; Chromatography, High Pressure Liquid ; Humans ; Permeability ; Positron-Emission Tomography/methods ; Protein Binding ; Radioisotopes/chemistry ; Radioisotopes/metabolism ; Tomography, Emission-Computed, Single-Photon/methods
Chemical Substances	Blood Proteins ; Radioisotopes
Language	English
Publishing date	2012-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1138098-6
ISSN	1872-9614 ; 0883-2897 ; 0969-8051
ISSN (online)	1872-9614
ISSN	0883-2897 ; 0969-8051
DOI	10.1016/j.nucmedbio.2011.06.011
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1090: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Rapid Iododeboronation with and without Gold Catalysis: Application to Radiolabelling of Arenes.

Webster, Stacey / O'Rourke, Kerry M / Fletcher, Conor / Pimlott, Sally L / Sutherland, Andrew / Lee, Ai-Lan

Chemistry (Weinheim an der Bergstrasse, Germany)

2017 Volume 24, Issue 4, Page(s) 937–943

Abstract: Radiopharmaceuticals that incorporate radioactive iodine in combination with single-photon emission computed tomography imaging play a key role in nuclear medicine, with applications in drug development and disease diagnosis. Despite this importance, ... ...

Abstract	Radiopharmaceuticals that incorporate radioactive iodine in combination with single-photon emission computed tomography imaging play a key role in nuclear medicine, with applications in drug development and disease diagnosis. Despite this importance, there are relatively few general methods for the incorporation of radioiodine into small molecules. This work reports a rapid air- and moisture-stable ipso-iododeboronation procedure that uses NIS in the non-toxic, green solvent dimethyl carbonate. The fast reaction and mild conditions of the gold-catalysed method led to the development of a highly efficient process for the radiolabelling of arenes, which constitutes the first example of an application of homogenous gold catalysis to selective radiosynthesis. This was exemplified by the efficient synthesis of radiolabelled meta-[
Language	English
Publishing date	2017-12-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1478547-X
ISSN	1521-3765 ; 0947-6539
ISSN (online)	1521-3765
ISSN	0947-6539
DOI	10.1002/chem.201704534
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Exploring the functionalisation of the thieno[2,3-d]pyrimidinedione core: Late stage access to highly substituted 5-carboxamide-6-aryl scaffolds

O'Rourke, Kerry M / Andrew Sutherland / Erin S. Johnstone / Holger M. Becker / Sally L. Pimlott

Tetrahedron. 2018,

2018

Abstract: The thieno[2,3-d]pyrimidinedione core is found as a component in a range of pharmaceutically active compounds, however, synthetic approaches to these scaffolds rely on access to functionalised, highly substituted thiophenes. Here we describe a new ... ...

Abstract	The thieno[2,3-d]pyrimidinedione core is found as a component in a range of pharmaceutically active compounds, however, synthetic approaches to these scaffolds rely on access to functionalised, highly substituted thiophenes. Here we describe a new approach for the preparation of 5-carboxamide-6-aryl analogues that involves a two-step synthesis of the thieno[2,3-d]pyrimidinedione core from a readily available mercaptouracil derivative. Thio-alkylation with ethyl 3-bromopyruvate, followed by cyclisation and dehydration mediated by polyphosphoric acid allowed the scalable synthesis of the thieno[2,3-d]pyrimidinedione unit. The late-stage functionalisation of this core motif via bromination of the thiophene ring and a subsequent Suzuki-Miyaura reaction as the key steps permitted access to a novel library of 5-carboxamide-6-aryl analogues. The physicochemical properties of these compounds were determined, generating an insight into the potential bioavailability of these scaffolds. Based on these results, a selection of the novel 5-carboxamide-6-aryl analogues were tested as lactate uptake inhibitors of monocarboxylate transporters 1, 2 and 4 in Xenopus oocytes.
Keywords	active ingredients ; bioavailability ; bromination ; chemical structure ; lactic acid ; oocytes ; physicochemical properties ; Suzuki reaction ; synthesis ; thiophene ; transporters ; Xenopus
Language	English
Size	p. .
Publishing place	Elsevier Ltd
Document type	Article
Note	Pre-press version
ZDB-ID	204285-x
ISSN	1464-5416 ; 0040-4020 ; 0563-2064
ISSN (online)	1464-5416
ISSN	0040-4020 ; 0563-2064
DOI	10.1016/j.tet.2018.06.019
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.B 1076: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito