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  1. Article ; Online: Renal denervation for the treatment of hypertension. Back and stronger.

    Rodriguez-Leor, Oriol / Troya, Maribel

    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

    2022  Volume 41, Issue 4, Page(s) 321–324

    Language Portuguese
    Publishing date 2022-02-09
    Publishing country Portugal
    Document type Journal Article
    ZDB-ID 632718-7
    ISSN 2174-2030 ; 0870-2551 ; 0304-4750
    ISSN (online) 2174-2030
    ISSN 0870-2551 ; 0304-4750
    DOI 10.1016/j.repc.2021.12.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Results from the ACI-SEC Infarction Code Registry. The ECG also exists. Response.

    Rodríguez-Leor, Oriol / Rosselló, Xavier / Cid-Álvarez, Ana Belén / Pérez de Prado, Armando

    Revista espanola de cardiologia (English ed.)

    2023  Volume 76, Issue 7, Page(s) 577

    MeSH term(s) Humans ; Infarction ; Registries ; Electrocardiography/methods
    Language Spanish
    Publishing date 2023-04-28
    Publishing country Spain
    Document type Letter
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2023.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In-stent restenosis percutaneous coronary intervention after chimney stenting during transcatheter aortic valve-in-valve implantation.

    Andrés-Cordón, Joan F / Armario, Xavier / Fernández-Nofrerias, Eduard / Carrillo, Xavier / Rodríguez-Leor, Oriol

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2023  Volume 19, Issue 2, Page(s) e191–e192

    MeSH term(s) Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Coronary Restenosis ; Stents ; Percutaneous Coronary Intervention/adverse effects ; Transcatheter Aortic Valve Replacement/adverse effects ; Aortic Valve Stenosis/surgery ; Treatment Outcome ; Heart Valve Prosthesis
    Language English
    Publishing date 2023-06-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-22-00891
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A debate

    Oriol Rodríguez-Leor

    REC: Interventional Cardiology, Vol 1, Iss 2, Pp 120-

    Denervación renal. Perspectiva del intervencionista

    2019  Volume 122

    Abstract: PREGUNTA: Tras los negativos resultados del estudio SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension), ¿qué nuevos ensayos permiten pensar de nuevo en la denervación renal (DR) como opción terapéutica? RESPUESTA: Los ... ...

    Abstract PREGUNTA: Tras los negativos resultados del estudio SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension), ¿qué nuevos ensayos permiten pensar de nuevo en la denervación renal (DR) como opción terapéutica? RESPUESTA: Los resultados del estudio SYMPLICITY HTN-31 fueron del todo inesperados, sobre todo porque los que teníamos cierta experiencia con la técnica habíamos vivido una realidad completamente distinta. Las limitaciones del estudio se resumen en una discutible selección de los pacientes (con tratamiento farmacológico no optimizado que se ajustó durante el seguimiento y que generó una respuesta inesperadamente positiva en el grupo control), una falta de experiencia por parte de los operadores (la mayoría de ellos realizaron las primeras intervenciones dentro del estudio) y una falta de conocimiento sobre cómo realizar la intervención para optimizar los resultados. Tras el análisis detallado de los resultados del SYMPLICITY HTN-31 se diseñaron dos estudios, con un dispositivo mejorado para realizar la intervención, cuyos resultados se han presentado recientemente. El primer estudio, el SPYRAL HTN-OFF MED2 fue un ensayo clínico aleatorizado, simulado (con grupo sham control) como prueba de concepto sobre la eficacia de la DR para disminuir la presión arterial (PA) en pacientes sin tratamiento farmacológico concomitante. Se incluyeron pacientes con hipertensión arterial (HTA) de.
    Keywords Internal medicine ; RC31-1245
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher Permanyer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Debate

    Oriol Rodríguez-Leor

    REC: Interventional Cardiology (English Ed.), Vol 1, Iss 2, Pp 120-

    Renal denervation. The interventional cardiologist perspective

    2019  Volume 122

    Abstract: QUESTION: After the negative results of the SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension) study, what new studies are dealing with renal denervation (RD) as a possible therapeutic option? ANSWER: The results of the ... ...

    Abstract QUESTION: After the negative results of the SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension) study, what new studies are dealing with renal denervation (RD) as a possible therapeutic option? ANSWER: The results of the SYMPLICITY HTN-3 study1 were totally unexpected, particularly because those of us who had some sort of experience with this technique had lived a completely dif-ferent reality. The limitations of the study have to do with the arguable selection of patients (with non-optimized pharmacological treatment that was adjusted during follow-up and generated an unexpectedly positive response in the control group), the operators’ lack of experience (most of them conducted their first procedures within the study), and the lack of knowledge on how to conduct this procedure in order to optimize the results. After the detailed analysis of the SYMPLICITY HTN-3 study,1 two different studies were designed with an improved device to conduct the procedure and their results have recently been made public. The first study, the SPYRAL HTN-OFF MED2 was a randomized sham-controlled clinical trial (with a sham control group) as the proof-of-concept on the efficacy of RD to reduce arterial blood pressure (BP) in patients without concomitant pharmacological treatment. Patients with mild-to-moderate arterial hypertension (HT) (office systolic.
    Keywords Medicine ; R
    Subject code 616
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher Permanyer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: ST-Segment Elevation Myocardial Infarction Care During COVID-19: Losing Sight of the Forest for the Trees.

    Rodriguez-Leor, Oriol / Cid-Alvarez, Belen

    JACC. Case reports

    2020  Volume 2, Issue 10, Page(s) 1625–1627

    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country Netherlands
    Document type Editorial ; Comment
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.04.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Initial experience with the coronary sinus reducer for the treatment of refractory angina in Spain.

    Rodríguez-Leor, Oriol / Jiménez Valero, Santiago / Gómez-Lara, Josep / Escaned, Javier / Avanzas, Pablo / Fernández, Saleta

    Revista espanola de cardiologia (English ed.)

    2022  Volume 76, Issue 5, Page(s) 381–383

    MeSH term(s) Humans ; Spain/epidemiology ; Coronary Sinus/surgery ; Angina Pectoris/surgery ; Treatment Outcome
    Language Spanish
    Publishing date 2022-12-17
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2022.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Simple Low-Cost Electrocardiogram Synchronizer.

    Amorós, Susana / Gálvez-Montón, Carolina / Rodríguez-Leor, Oriol / O'Callaghan, Juan Manuel

    Sensors (Basel, Switzerland)

    2021  Volume 21, Issue 17

    Abstract: Electrocardiogram (ECG) synchronization is useful to avoid the effects of cardiac motion in medical measurements, and is widely used in standard medical imaging. A number of medical equipment include embedded commercial synchronizers. However, the use of ...

    Abstract Electrocardiogram (ECG) synchronization is useful to avoid the effects of cardiac motion in medical measurements, and is widely used in standard medical imaging. A number of medical equipment include embedded commercial synchronizers. However, the use of independent synchronization modules is sometimes needed when several non-integrated instruments are used, or in the development of new medical instruments and procedures. We present a simple low-cost ECG synchronizer module based on an Arduino controller board that converts the ECG signal into a transistor-transistor-logic (TTL) one, allowing real-time medical measurements triggered at specific phases of the cardiac cycle. The device and conversion algorithm developed is optimized in vitro using synthetic and human ECG signals, and tested in vivo on three swine specimens. Error rates during the in vivo testing stage remain below the 2% of the cycles in all animals and critical false positives are less than 1%, which is sufficient for most applications. Possible algorithm updates are discussed if its performance needs to be improved.
    MeSH term(s) Algorithms ; Animals ; Electrocardiography ; Heart ; Signal Processing, Computer-Assisted ; Swine
    Language English
    Publishing date 2021-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s21175885
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  9. Article ; Online: Antiarrhythmic and Anti-Inflammatory Effects of Sacubitril/Valsartan on Post-Myocardial Infarction Scar.

    Martínez-Falguera, Daina / Aranyó, Júlia / Teis, Albert / Ferrer-Curriu, Gemma / Monguió-Tortajada, Marta / Fadeuilhe, Edgar / Rodríguez-Leor, Oriol / Díaz-Güemes, Idoia / Roura, Santiago / Villuendas, Roger / Sarrias, Axel / Bazan, Victor / Delgado, Victoria / Bayes-Genis, Antoni / Bisbal, Felipe / Gálvez-Montón, Carolina

    Circulation. Arrhythmia and electrophysiology

    2024  , Page(s) e012517

    Abstract: Background: Sacubitril/valsartan (Sac/Val) is superior to angiotensin-converting enzyme inhibitors in reducing the risk of heart failure hospitalization and cardiovascular death, but its mechanistic data on myocardial scar after myocardial infarction ( ... ...

    Abstract Background: Sacubitril/valsartan (Sac/Val) is superior to angiotensin-converting enzyme inhibitors in reducing the risk of heart failure hospitalization and cardiovascular death, but its mechanistic data on myocardial scar after myocardial infarction (MI) are lacking. The objective of this work was to assess the effects of Sac/Val on inflammation, fibrosis, electrophysiological properties, and ventricular tachycardia inducibility in post-MI scar remodeling in swine.
    Methods: After MI, 22 pigs were randomized to receive β-blocker (BB; control, n=8) or BB+Sac/Val (Sac/Val, n=9). The systemic immune response was monitored. Cardiac magnetic resonance data were acquired at 2-day and 29-day post MI to assess ventricular remodeling. Programmed electrical stimulation and high-density mapping were performed at 30-day post MI to assess ventricular tachycardia inducibility. Myocardial samples were collected for histological analysis.
    Results: Compared with BB, BB+Sac/Val reduced acute circulating leukocytes (
    Conclusions: After MI, compared with BB, BB+Sac/Val was associated with reduced acute systemic inflammatory markers, reduced total scar and border zone mass on late gadolinium-enhanced magnetic resonance imaging, and lower ventricular tachycardia inducibility.
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2426129-4
    ISSN 1941-3084 ; 1941-3149
    ISSN (online) 1941-3084
    ISSN 1941-3149
    DOI 10.1161/CIRCEP.123.012517
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  10. Article ; Online: Descenso del número de angioplastias primarias durante la pandemia y su relación con la mortalidad por COVID-19. El papel de los riesgos competitivos.

    Aldama, Guillermo / Rebollal, Fernando / Flores, Xacobe / Piñón, Pablo / Rodríguez-Leor, Oriol / Vázquez, José Manuel

    Revista espanola de cardiologia

    2020  Volume 74, Issue 5, Page(s) 474–476

    Title translation Decrease in the number of primary angioplasty procedures during the pandemic and its relationship with mortality from COVID-19. The role of competing risks.
    Language Spanish
    Publishing date 2020-11-19
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 128925-1
    ISSN 1579-2242 ; 0300-8932
    ISSN (online) 1579-2242
    ISSN 0300-8932
    DOI 10.1016/j.recesp.2020.11.008
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