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  1. Article ; Online: Safer intubation and extubation of patients with COVID-19.

    Asenjo, Juan Francisco

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2020  Volume 67, Issue 9, Page(s) 1276–1278

    MeSH term(s) Airway Extubation/methods ; Anesthesia, General/methods ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; Intubation, Intratracheal/methods ; Pandemics ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Respiration, Artificial/methods ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-22
    Publishing country United States
    Document type Letter
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-020-01666-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Safer intubation and extubation of patients with COVID-19

    Asenjo, Juan Francisco

    Canadian Journal of Anesthesia/Journal canadien d'anesthésie

    2020  Volume 67, Issue 9, Page(s) 1276–1278

    Keywords Anesthesiology and Pain Medicine ; General Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-020-01666-9
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Cancer shoulder pain treated with a neurolytic erector spinae plane block.

    Papa, Patricia / Antunez-Maciel, Mariano / Asenjo, Juan-Francisco

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2020  Volume 67, Issue 9, Page(s) 1262–1263

    MeSH term(s) Cancer Pain/etiology ; Humans ; Neoplasms/complications ; Nerve Block ; Paraspinal Muscles/diagnostic imaging ; Shoulder Pain/etiology
    Language English
    Publishing date 2020-03-25
    Publishing country United States
    Document type Letter
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-020-01633-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cardiovascular events risk in patients with systemic autoimmune diseases: a prognostic systematic review and meta-analysis.

    Asenjo-Lobos, Claudia / González, Leticia / Bulnes, Juan Francisco / Roque, Marta / Muñoz Venturelli, Paula / Rodríguez, Gonzalo Martínez

    Clinical research in cardiology : official journal of the German Cardiac Society

    2023  Volume 113, Issue 2, Page(s) 246–259

    Abstract: Background: Chronic inflammation is considered a risk factor for the development of atherosclerosis and cardiovascular (CV) events. We seek to assess the risk of CV events in patients with Systemic autoimmune diseases (SAD), such as Systemic Lupus ... ...

    Abstract Background: Chronic inflammation is considered a risk factor for the development of atherosclerosis and cardiovascular (CV) events. We seek to assess the risk of CV events in patients with Systemic autoimmune diseases (SAD), such as Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), Psoriasis (Ps) and Ankylosing Spondylitis (AS), compared with the general population.
    Methods and results: A systematic search of MEDLINE from inception up to May 2021 was performed. Observational studies including individuals with and without autoimmune diseases (SLE, RA, Ps, AS), which reported a measure of association and variability for the effect of SAD on CV events, were included. The random effects meta-analysis was performed using the Hartung-Knapp-Sidik-Jonkman approach to obtain the pooled estimates. Cardiovascular Events including CV mortality, non-fatal myocardial infarction (MI), non-fatal stroke and coronary revascularization were the main outcomes evaluated. Fifty-four studies were selected, with a total of 24,107,072 participants. The presence of SAD was associated with an increased risk of CV mortality (HR 1.49 [95% CI 1.10-2.03]), non-fatal MI (HR 1.42 [95% CI 1.23-1.62]), and non-fatal stroke (HR 1.47 [95% CI 1.28-1.70]). RA, SLE, and Ps (particularly with arthritis) were significantly associated with a higher risk of MI and stroke. SAD was also associated with an increased risk of Major Adverse Cardiovascular Events (MACE) (HR 1.45 [95% CI 1.16-1.83]).
    Conclusion: Patients with SAD present an increased risk of CV morbidity and mortality, which should be considered when establishing therapeutic strategies. These findings support the role of systemic inflammation in the development of atherosclerosis-driven disease.
    MeSH term(s) Humans ; Prognosis ; Risk Factors ; Myocardial Infarction/epidemiology ; Arthritis, Rheumatoid/complications ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/epidemiology ; Stroke ; Atherosclerosis/complications ; Inflammation ; Cardiovascular Diseases/etiology
    Language English
    Publishing date 2023-08-31
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-023-02291-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Efficacy of Systemic Lidocaine in the Management of Chronic Pain: A Literature Review.

    Yousefshahi, Fardin / Predescu, Oana / Francisco Asenjo, Juan

    Anesthesiology and pain medicine

    2017  Volume 7, Issue 3, Page(s) e44732

    Abstract: Context: Despite recent advances in the understanding of the chronic pain concept, its diagnosis and management remains a daily challenge for clinicians and patients. Based on the published literature, this review discusses and tries to organize the ... ...

    Abstract Context: Despite recent advances in the understanding of the chronic pain concept, its diagnosis and management remains a daily challenge for clinicians and patients. Based on the published literature, this review discusses and tries to organize the current knowledge and the up-to-date clinical experience about the efficacy and safety of the use of intravenous lidocaine in treatment and prevention of chronic pain.
    Evidence acquisition: To prepare this narrative review, we performed an in depth literature review using the PubMed searching engine. We extracted all relevant articles published in English, up to April 2016.
    Results: Lidocaine, administered as transdermal patch or intravenous lidocaine, is a safe and effective modality in the treatment of post-herpetic neuralgia (PHN), complex regional pain syndrome, as well and for prevention of chronic pain. It may be effective in the management of neuropathic pain syndromes, chronic pain, post-operative pain, and refractory cancer pain.
    Conclusions: Intravenous lidocaine and lidocaine patch are effective and safe for the treatment of several chronic or neuropathic pain syndromes. The use of lidocaine during surgery could prevent the development of some chronic post-surgical pain syndromes.
    Language English
    Publishing date 2017-04-22
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 3018888-X
    ISSN 2228-7531 ; 2228-7523
    ISSN (online) 2228-7531
    ISSN 2228-7523
    DOI 10.5812/aapm.44732
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neuropathic pain after thoracotomy: Tracking signs and symptoms before and at monthly intervals following surgery.

    Gandhi, Wiebke / Pomares, Florence B / Naso, Lina / Asenjo, Juan-Francisco / Schweinhardt, Petra

    European journal of pain (London, England)

    2020  Volume 24, Issue 7, Page(s) 1269–1289

    Abstract: Background: As the development of neuropathic symptoms contributes to pain severity and chronification after surgery, their early prediction is important to allow targeted treatment.: Objectives: We longitudinally investigated trajectories of signs ... ...

    Abstract Background: As the development of neuropathic symptoms contributes to pain severity and chronification after surgery, their early prediction is important to allow targeted treatment.
    Objectives: We longitudinally investigated trajectories of signs and symptoms in patients undergoing thoracotomy and assessed whether and at which time they were related to the development of neuropathic pain symptoms 6 months after surgery.
    Methods: Presurgical and 6 monthly postsurgical assessments included questionnaires for mental and physical well-being (e.g., depression/anxiety, pain catastrophizing, sleep quality, neuropathic pain symptoms), and quantitative sensory testing (QST).
    Results: QST trajectories indicated nerve impairment of the surgery site with predominant loss of function. Signs of recovery towards the end of the assessment period were observed for some tests. Unsupervised cluster analysis with NPSI scores 6 months after surgery as clustering variable identified one group with no/low levels of neuropathic symptoms and one with moderate levels. The two groups differed w.r.t. several signs and symptoms already at early time points. Notably, neuropathic pain anywhere in the body differed already preoperatively and sleep impairment differentiated the two groups at all time points. Regression analysis revealed three factors that seemed particularly suited to predicted 6 months NPSI scores, namely preoperative neuropathic pain symptoms, with contributions from sleep impairment 1 month after surgery and the presence of dynamic mechanical allodynia 3 months after surgery.
    Conclusions: Clinical routine should focus on the individual's physiological state, including pre-existing neuropathic pain and sleep quality to identify patients early who might be at risk to develop chronic post-surgical neuropathic pain.
    Significance: Development of neuropathies contributes to pain severity and pain chronification after surgery. Here we demonstrate trajectories of quantitative sensory tests (assessed at monthly intervals for 6 months after surgery) that reveal accurate time courses of gain/loss of nerve function following thoracotomy. Independent of the degree of neuropathic signs after surgery, the main predictors for post-surgical neuropathic pain are self-reported neuropathic pain before surgery and sleep quality shortly after surgery.
    MeSH term(s) Humans ; Hyperalgesia ; Neuralgia/diagnosis ; Neuralgia/etiology ; Pain Measurement ; Pain, Postoperative/diagnosis ; Pain, Postoperative/epidemiology ; Thoracotomy/adverse effects
    Language English
    Publishing date 2020-05-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1390424-3
    ISSN 1532-2149 ; 1090-3801
    ISSN (online) 1532-2149
    ISSN 1090-3801
    DOI 10.1002/ejp.1569
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Retrospective review of two-port thoracoscopic (VATS) wedge bullectomy and lung wedge biopsy

    Jimmy Bejjani / Guillaume Couture / Juan-Francisco Asenjo / Marco Sirois / Chantal Sirois / Christian Sirois

    McGill Journal of Medicine, Vol 12, Iss

    2020  Volume 1

    Abstract: Background: Video-assisted thoracoscopic surgery (VATS) involving wedge resection of bulla and lung biopsy can be done by two or three-port incisions. Controversy exists as to which approach is superior. We communicate our experience with two-port VATS ... ...

    Abstract Background: Video-assisted thoracoscopic surgery (VATS) involving wedge resection of bulla and lung biopsy can be done by two or three-port incisions. Controversy exists as to which approach is superior. We communicate our experience with two-port VATS for these procedures. Methods: We retrospectively analyzed the charts of all patients who underwent a VATS procedure by two-port incisions from July 2001 to July 2007 by two thoracic surgeons (S.C., S.C.) We included in the study all patients who underwent wedge resections for primary or secondary spontaneous pneumothorax and biopsies for pulmonary infiltrates and small nodules. Results: A total of 319 patients’ charts were examined, and 217 of whom had undergone two-port incisions fitted in the inclusion criteria. There were 136 (65.7%) males and 81 (37.3%) females with a mean age of 47 years. Pneumothorax was the main diagnosis for 98 (45%) patients, followed by pulmonary infiltrates for 69 (32%) patients and lung nodules for 50 (23%) patients. The mean operative time and the number of post-op days for chest tube removal and to discharge home in each group have also been recorded. There were few post-operative complications, such as 11 (5%) cases of persistent air leak, 11 (5%) cases of transient fever of unknown origin, 3 (1.4%) cases of pneumonia, 3 (1.4%) cases of bleeding within, one reoperated, and 1 (0.46%) case of C. difficile colitis. The 30-day mortality was 0%. Conclusion: The thoracoscopic (VATS) wedge biopsy via two-port incisions is a safe operation for patients presenting with pneumothorax or requiring a lung biopsy. A two-port approach seems to be a reasonable alternative to three-port incision procedures for these types of diagnosis, regarding post-operative pain and cosmetic benefits particularly for young patients.
    Keywords vats ; pneumothorax ; bullectomy ; thoracoscopy ; pleurodesis ; pulmonary nodule ; pulmonary infiltrates ; lung neoplasms ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher McGill University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Postthoracotomy Ipsilateral Shoulder Pain: A Literature Review on Characteristics and Treatment.

    Yousefshahi, Fardin / Predescu, Oana / Colizza, Melissa / Asenjo, Juan Francisco

    Pain research & management

    2016  Volume 2016, Page(s) 3652726

    Abstract: Context. ...

    Abstract Context.
    MeSH term(s) Analgesia, Epidural/methods ; Functional Laterality/physiology ; Humans ; Pain, Postoperative/etiology ; Pain, Postoperative/therapy ; PubMed/statistics & numerical data ; Shoulder Pain/etiology ; Shoulder Pain/therapy ; Thoracotomy/adverse effects
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2041085-2
    ISSN 1918-1523 ; 1203-6765
    ISSN (online) 1918-1523
    ISSN 1203-6765
    DOI 10.1155/2016/3652726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Vertebroplasty and kyphoplasty: new evidence adds heat to the debate.

    Asenjo, Juan-Francisco / Rossel, Felipe

    Current opinion in anaesthesiology

    2012  Volume 25, Issue 5, Page(s) 577–583

    Abstract: Purpose of review: Cement bone augmentation has become very popular worldwide in treating painful noncomplicated spine fractures. Controversy about the effectiveness was raised by two randomized trials in 2009. Recent new evidence contradicts those ... ...

    Abstract Purpose of review: Cement bone augmentation has become very popular worldwide in treating painful noncomplicated spine fractures. Controversy about the effectiveness was raised by two randomized trials in 2009. Recent new evidence contradicts those findings giving credit to vertebroplasty/kyphoplasty.
    Recent findings: Well designed prospective clinical trials in cancer and noncancer vertebral fractures as well as an excellent meta-analysis showed that painful vertebral compression fractures have better and faster pain relief, better functional outcomes, and with low complication rate when treated with percutaneous cement than conservatively.
    Summary: The saga is unfinished. The treatment of vertebral compression fractures with cement augmentation is still in its infancy. The potential for development with new materials and the injection of biologic and active bone cements or anticancer products, in metastatic disease, will revolutionize the treatment of this condition.
    MeSH term(s) Anesthesia ; Bone Cements ; Contraindications ; Cost-Benefit Analysis ; Humans ; Kyphoplasty/adverse effects ; Kyphoplasty/methods ; Neoplasms/complications ; Osteoporosis/complications ; Randomized Controlled Trials as Topic ; Spinal Fractures/etiology ; Spinal Fractures/surgery ; Treatment Outcome ; Vertebroplasty/adverse effects ; Vertebroplasty/methods
    Chemical Substances Bone Cements
    Language English
    Publishing date 2012-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0b013e328357a2c7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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