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  1. Article ; Online: Magnetic assembly of plasmonic chiral superstructures with dynamic chiroptical responses.

    Wu, Chaolumen / Fan, Qingsong / Li, Zhiwei / Ye, Zuyang / Yin, Yadong

    Materials horizons

    2024  Volume 11, Issue 3, Page(s) 680–687

    Abstract: Plasmonic nanostructures exhibiting dynamically tunable chiroptical responses hold great promise for broad applications such as sensing, catalysis, and enantioselective analysis. Despite the successful fabrication of chiral structures through diverse ... ...

    Abstract Plasmonic nanostructures exhibiting dynamically tunable chiroptical responses hold great promise for broad applications such as sensing, catalysis, and enantioselective analysis. Despite the successful fabrication of chiral structures through diverse templates, creating dynamic chiroptical materials with fast and reversible responses to external stimuli is still challenging. This work showcases reversible magnetic assembly and active tuning of plasmonic chiral superstructures by introducing a chiral magnetic field from a cubic permanent magnet. Manipulating the strength and direction of the magnetic field controls both the chiral arrangement and plasmonic coupling of the nanoparticle assembly, enabling fast and reversible tunability in not only the handedness of the superstructures but also the spectral characteristics of their chiroptical properties. The dynamic tunability further enables the fabrication of color-changing optical devices based on the optical rotatory dispersion effect, showcasing their potential for application in anti-counterfeiting and stress sensors.
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2744250-0
    ISSN 2051-6355 ; 2051-6347
    ISSN (online) 2051-6355
    ISSN 2051-6347
    DOI 10.1039/d3mh01597a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Research Progress in Oxygen Carrier Design and Application.

    Ye, Qingsong / Zheng, Deyuan / Chen, Kaiyuan / Wu, Jinhui

    Molecular pharmaceutics

    2023  Volume 20, Issue 9, Page(s) 4373–4386

    Abstract: Ischemia or hypoxia can lead to pathological changes in the metabolism and function of tissues and then lead to various diseases. Timely and effective blood resuscitation or improvement of hypoxia is very important for the treatment of diseases. However, ...

    Abstract Ischemia or hypoxia can lead to pathological changes in the metabolism and function of tissues and then lead to various diseases. Timely and effective blood resuscitation or improvement of hypoxia is very important for the treatment of diseases. However, there is a need to develop stable, nontoxic, and immunologically inert oxygen carriers due to limitations such as blood shortages, different blood types, and the risk of transmitting infections. With the development of various technologies, oxygen carriers based on hemoglobin and perfluorocarbon have been widely studied in recent years. This paper reviews the development and application of hemoglobin and perfluorocarbon oxygen carriers. The design of oxygen carriers was analyzed, and their application as blood substitutes or oxygen carriers in various hypoxic diseases was discussed. Finally, the characteristics and future research of ideal oxygen carriers were prospected to provide reference for follow-up research.
    MeSH term(s) Humans ; Oxygen ; Blood Substitutes ; Fluorocarbons ; Hemoglobins ; Hypoxia
    Chemical Substances Oxygen (S88TT14065) ; Blood Substitutes ; Fluorocarbons ; Hemoglobins
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2138405-8
    ISSN 1543-8392 ; 1543-8384
    ISSN (online) 1543-8392
    ISSN 1543-8384
    DOI 10.1021/acs.molpharmaceut.3c00289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6250: Show issues Location:
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  3. Article ; Online: Colorimetric Pressure Sensing by Plasmonic Decoupling of Silver Nanoparticles Confined within Polymeric Nanoshells.

    Chen, Chen / Fan, Qingsong / Li, Zhiwei / Cai, Zepeng / Ye, Zuyang / Yin, Yadong

    Nano letters

    2024  Volume 24, Issue 12, Page(s) 3737–3743

    Abstract: Employing a plasmonic decoupling mechanism, we report the design of a colorimetric pressure sensor that can respond to applied pressure with instant color changes. The sensor consists of a thin film of stacked uniform resorcinol-formaldehyde nanoshells ... ...

    Abstract Employing a plasmonic decoupling mechanism, we report the design of a colorimetric pressure sensor that can respond to applied pressure with instant color changes. The sensor consists of a thin film of stacked uniform resorcinol-formaldehyde nanoshells with their inner surfaces functionalized with silver nanoparticles. Upon compression, the flexible polymer nanoshells expand laterally, inducing plasmonic decoupling between neighboring silver nanoparticles and a subsequent blue-shift. The initial color of the sensor is determined by the extent of plasmonic coupling, which can be controlled by tuning the interparticle distance through a seeded growth process. The sensing range can be conveniently customized by controlling the polymer shell thickness or incorporating hybrid nanoshells into various polymer matrices. The new colorimetric pressure sensors are easy to fabricate and highly versatile, allow for convenient tuning of the sensing range, and feature significant color shifts, holding great promise for a wide range of practical applications.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.4c00268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Assessment of the osteogenic effect after maxillary sinus floor elevation and simultaneous implantation with or without bone grafts by analyzing trabecular bone parameters: a retrospective study.

    Wang, Mohan / Li, Beibei / Feng, Hailiang / Ye, Qingsong / Sun, Yahui / Duan, Xinxiu / He, Jiacai

    Journal of applied oral science : revista FOB

    2024  Volume 32, Page(s) e20230406

    Abstract: Objective: The aim of this population-based retrospective study was to compare the osteogenic effect of newly formed bone after maxillary sinus floor elevation (MSFE) and simultaneous implantation with or without bone grafts by quantitatively analyzing ... ...

    Abstract Objective: The aim of this population-based retrospective study was to compare the osteogenic effect of newly formed bone after maxillary sinus floor elevation (MSFE) and simultaneous implantation with or without bone grafts by quantitatively analyzing trabecular bone parameters.
    Methodology: A total of 100 patients with missing posterior maxillary teeth who required MSFE and implantation were included in this study. Patients were divided into two groups: the non-graft group (n=50) and the graft group (n=50). Radiographic parameters were measured using cone beam computed tomography (CBCT), and the quality of newly formed bone was analyzed by assessing trabecular bone parameters using CTAn (CTAnalyzer, SkyScan, Antwerp, Belgium) software.
    Results: In the selected regions of interest, the non-graft group showed greater bone volume/total volume (BV/TV), bone surface/total volume (BS/TV), trabecular number (Tb. N), and trabecular thickness (Tb. Th) than the graft group (p<0.001). The non-graft group showed lower trabecular separation (Tb. Sp) than the graft group (p<0.001). The incidence of perforation and bleeding was higher in the graft group than in the non-graft group (p<0.001), but infection did not significantly differ between groups (p>0.05). Compared to the graft group, the non-graft group showed lower postoperative bone height, gained bone height and apical bone height (p<0.001).
    Conclusion: MSFE with and without bone grafts can significantly improve bone formation. In MSFE, the use of bone grafts hinders the formation of good quality bone, whereas the absence of bone grafts can generate good bone quality and limited bone mass.
    MeSH term(s) Humans ; Sinus Floor Augmentation/methods ; Retrospective Studies ; Osteogenesis ; Maxillary Sinus/diagnostic imaging ; Maxillary Sinus/surgery ; Cancellous Bone
    Language English
    Publishing date 2024-02-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2152066-5
    ISSN 1678-7765 ; 1678-7765
    ISSN (online) 1678-7765
    ISSN 1678-7765
    DOI 10.1590/1678-7757-2023-0406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Adsorption Behavior of Organoarsenicals over MnFe

    Gu, Binxian / Zhang, Haijie / Ye, Meng / Zhou, Ting / Yi, Jianjian / Hu, Qingsong

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 24

    Abstract: As a kind of emerging contaminant, organoarsenic compounds have drawn wide concern because of their considerable solubilities in water, and the highly toxic inorganic arsenic species formed during their biotic and abiotic degradation in the natural ... ...

    Abstract As a kind of emerging contaminant, organoarsenic compounds have drawn wide concern because of their considerable solubilities in water, and the highly toxic inorganic arsenic species formed during their biotic and abiotic degradation in the natural environment. Thus, the effective removal and studying of the adsorption mechanism of organoarsenic compounds are of significant urgency. In this work, MnFe
    Language English
    Publishing date 2023-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16247636
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  6. Article ; Online: New trends in brain tumor immunity with the opportunities of lymph nodes targeted drug delivery.

    Qi, Yangzhi / Xiong, Wei / Chen, Qianxue / Ye, Zhifei / Jiang, Cailei / He, Yan / Ye, Qingsong

    Journal of nanobiotechnology

    2023  Volume 21, Issue 1, Page(s) 254

    Abstract: Lymph nodes targeted drug delivery is an attractive approach to improve cancer immunotherapy outcomes. Currently, the depth of understanding of afferent and efferent arms in brain immunity reveals the potential clinical applications of lymph node ... ...

    Abstract Lymph nodes targeted drug delivery is an attractive approach to improve cancer immunotherapy outcomes. Currently, the depth of understanding of afferent and efferent arms in brain immunity reveals the potential clinical applications of lymph node targeted drug delivery in brain tumors, e.g., glioblastoma. In this work, we systematically reviewed the microenvironment of glioblastoma and its structure as a basis for potential immunotherapy, including the glial-lymphatic pathway for substance exchange, the lymphatic drainage pathway from meningeal lymphatic vessels to deep cervical lymph nodes that communicate intra- and extracranial immunity, and the interaction between the blood-brain barrier and effector T cells. Furthermore, the carriers designed for lymph nodes targeted drug delivery were comprehensively summarized. The challenges and opportunities in developing a lymph nodes targeted delivery strategy for glioblastoma using nanotechnology are included at the end.
    MeSH term(s) Humans ; Glioblastoma/metabolism ; Lymph Nodes/metabolism ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Brain ; Drug Delivery Systems ; Tumor Microenvironment
    Language English
    Publishing date 2023-08-04
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-023-02011-0
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  7. Article: Application of thermosensitive-hydrogel combined with dental pulp stem cells on the injured fallopian tube mucosa in an animal model.

    Luo, Lihua / Zhu, Qunyan / Li, Yejian / Hu, Fengting / Yu, Jiangtao / Liao, Xiangyan / Xing, Zhenjie / He, Yan / Ye, Qingsong

    Frontiers in bioengineering and biotechnology

    2023  Volume 10, Page(s) 1062646

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2023-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.1062646
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  8. Article ; Online: Correction: Metal-organic framework materials promote neural differentiation of dental pulp stem cells in spinal cord injury.

    Zhou, Heng / Jing, Shuili / Xiong, Wei / Zhu, Yangzhi / Duan, Xingxiang / Li, Ruohan / Peng, Youjian / Kumeria, Tushar / He, Yan / Ye, Qingsong

    Journal of nanobiotechnology

    2023  Volume 21, Issue 1, Page(s) 386

    Language English
    Publishing date 2023-10-24
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-023-02141-5
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  9. Article ; Online: Advances in isolation and extraction standardization and clinical translation of exosomes

    YE Qingsong / PENG Youjian / LUO Yu

    口腔疾病防治, Vol 30, Iss 9, Pp 609-

    2022  Volume 619

    Abstract: Exosomes are phospholipid bilayer vesicles secreted by living cells that can carry a variety of signaling molecules, such as RNA, DNA, protein, and lipids. Exosomes play a role in the transmission of signaling molecules between cells, thus regulating ... ...

    Abstract Exosomes are phospholipid bilayer vesicles secreted by living cells that can carry a variety of signaling molecules, such as RNA, DNA, protein, and lipids. Exosomes play a role in the transmission of signaling molecules between cells, thus regulating many physiological and pathological processes. The methods of extracting exosomes include differential centrifugation, density gradient centrifugation, exclusion chromatography, ultrafiltration, coprecipitation, polymer immune affinity, microfluidic separation technology, etc. Each of these extraction technologies has advantages and disadvantages; however, there is no unified international standard. In addition, the expression of specific proteins and genetic material of exosomes from different cell sources are different; thus, their expression characteristics and functions are also distinctive. Based on this situation, research on exosomes is limited to preclinical studies, and difficulties and challenges still exist in clinical application. This paper summarizes the progress of research in the field of exosomes, to understand the characteristics, modification and application of exosomes from different cell sources, and to summarize their advantages and disadvantages as well as challenges, which can help researchers better understand and master the performance of exosomes. Furthermore, improvement of standard procedures in the extraction and manufacturing of exosomes is important, as it will provide a reference for researchers to carry out exosome-related translational clinical research.
    Keywords exosomes ; exosomes isolation technique ; extraction methods of exosomes ; specificity ; standardization ; exosomes from stem cells ; exosomes from tumor cells ; preclinical studies ; tissue regeneration ; targeted drug delivery ; tumor resistance ; Medicine ; R
    Subject code 610
    Language Chinese
    Publishing date 2022-09-01T00:00:00Z
    Publisher Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: The oral-brain axis: can periodontal pathogens trigger the onset and progression of Alzheimer's disease?

    Li, Ruohan / Wang, Junnan / Xiong, Wei / Luo, Yu / Feng, Huixian / Zhou, Heng / Peng, Youjian / He, Yan / Ye, Qingsong

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1358179

    Abstract: Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by a progressive cognitive decline. Sporadic AD, accounting for more than 95% of cases, may arise due to the influence of environmental factors. It was reported that ... ...

    Abstract Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by a progressive cognitive decline. Sporadic AD, accounting for more than 95% of cases, may arise due to the influence of environmental factors. It was reported that periodontitis, a common oral ailment, shares several risk factors with AD, including advanced age, smoking, diabetes, and hypertension, among others. Periodontitis is an inflammatory disease triggered by dysbiosis of oral microorganisms, whereas Alzheimer's disease is characterized by neuroinflammation. Many studies have indicated that chronic inflammation can instigate brain AD-related pathologies, including amyloid-β plaques, Tau protein hyperphosphorylation, neuroinflammation, and neurodegeneration. The potential involvement of periodontal pathogens and/or their virulence factors in the onset and progression of AD by the oral-brain axis has garnered significant attention among researchers with ongoing investigations. This review has updated the periodontal pathogens potentially associated with AD, elucidating their impact on the central nervous system, immune response, and related pathological processes in the brain to provide valuable insights for future research on the oral-brain axis.
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1358179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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