LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 470

Search options

  1. Article ; Online: Hematologic cancer diagnosis and classification using machine and deep learning: State-of-the-art techniques and emerging research directives.

    Patel, Hema / Shah, Himal / Patel, Gayatri / Patel, Atul

    Artificial intelligence in medicine

    2024  Volume 152, Page(s) 102883

    Abstract: Hematology is the study of diagnosis and treatment options for blood diseases, including cancer. Cancer is considered one of the deadliest diseases across all age categories. Diagnosing such a deadly disease at the initial stage is essential to cure the ... ...

    Abstract Hematology is the study of diagnosis and treatment options for blood diseases, including cancer. Cancer is considered one of the deadliest diseases across all age categories. Diagnosing such a deadly disease at the initial stage is essential to cure the disease. Hematologists and pathologists rely on microscopic evaluation of blood or bone marrow smear images to diagnose blood-related ailments. The abundance of overlapping cells, cells of varying densities among platelets, non-illumination levels, and the amount of red and white blood cells make it more difficult to diagnose illness using blood cell images. Pathologists are required to put more effort into the traditional, time-consuming system. Nowadays, it becomes possible with machine learning and deep learning techniques, to automate the diagnostic processes, categorize microscopic blood cells, and improve the accuracy of the procedure and its speed as the models developed using these methods may guide an assisting tool. In this article, we have acquired, analyzed, scrutinized, and finally selected around 57 research papers from various machine learning and deep learning methodologies that have been employed in the diagnosis of leukemia and its classification over the past 20 years, which have been published between the years 2003 and 2023 by PubMed, IEEE, Science Direct, Google Scholar and other pertinent sources. Our primary emphasis is on evaluating the advantages and limitations of analogous research endeavors to provide a concise and valuable research directive that can be of significant utility to fellow researchers in the field.
    Language English
    Publishing date 2024-04-21
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 645179-2
    ISSN 1873-2860 ; 0933-3657
    ISSN (online) 1873-2860
    ISSN 0933-3657
    DOI 10.1016/j.artmed.2024.102883
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Spasticity evaluation and management tools.

    Howard, Ileana M / Patel, Atul T

    Muscle & nerve

    2023  Volume 67, Issue 4, Page(s) 272–283

    Abstract: Spasticity is a complex and often disabling symptom for patients with upper motor neuron syndromes. Although spasticity arises from neurological disease, it often cascades into muscle and soft tissue changes, which may exacerbate symptoms and further ... ...

    Abstract Spasticity is a complex and often disabling symptom for patients with upper motor neuron syndromes. Although spasticity arises from neurological disease, it often cascades into muscle and soft tissue changes, which may exacerbate symptoms and further hamper function. Effective management therefore hinges on early recognition and treatment. To this end, the definition of spasticity has expanded over time to more accurately reflect the spectrum of symptoms experienced by persons with this disorder. Once identified, clinical and research quantitative assessments of spasticity are hindered by the uniqueness of presentations both for individuals and for specific neurological diagnoses. Objective measures in isolation often fail to reflect the complex functional impact of spasticity. Multiple tools exist to quantitatively or qualitatively assess the severity of spasticity, including clinician and patient-reported measures as well as electrodiagnostic, mechanical, and ultrasound measures. A combination of objective and patient-reported outcomes is likely required to better reflect the burden of spasticity symptoms in an individual. Therapeutic options exist for the treatment of spasticity along a broad spectrum from nonpharmacologic to interventional procedures. Treatment strategies may include exercise, physical agent modalities, oral medications, injections, pumps, and surgery. Optimal spasticity management most often requires a multimodal approach, combining pharmacological management with interventions that match the functional needs, goals, and preferences of the patient. Physicians and other healthcare providers who manage spasticity must be familiarized with the full array of spasticity interventions and must frequently reassess results of treatment to ensure the patient's goals of treatment are met.
    MeSH term(s) Humans ; Muscle Spasticity/diagnosis ; Muscle Spasticity/etiology ; Muscle Spasticity/therapy ; Motor Neurons ; Physical Therapy Modalities
    Language English
    Publishing date 2023-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.27792
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Multidisciplinary collaborative consensus statement on the barriers and solutions to care access, patient and caregiver support, and clinical capacity and capability for patients with spasticity.

    Patel, Atul / Gellhorn, Alfred / Neerukonda, Kavitha / Kwasnica, Christina

    PM & R : the journal of injury, function, and rehabilitation

    2024  Volume 16, Issue 3, Page(s) 278–286

    Abstract: Background: There is evidence that patients with spasticity are not receiving adequate care. Identifying the unmet needs of patients with spasticity is essential to develop services and treatment strategies to better support this population This is an ... ...

    Abstract Background: There is evidence that patients with spasticity are not receiving adequate care. Identifying the unmet needs of patients with spasticity is essential to develop services and treatment strategies to better support this population This is an effort to identify challenges related to treatment of spasticity and provide the springboard for the implementation of identified solutions.
    Objective: To identify the main barriers to spasticity care and identify potential solutions.
    Design: Delphi process.
    Setting: Expert panel.
    Participants: A total of 35 participants with diverse experience and knowledge related to spasticity care were invited and 29 attended an in-person 2022 Spasticity Summit hosted by the American Academy of Physical Medicine and Rehabilitation.
    Methods: The expert panel participated in a presummit survey to identify the main potential barriers to spasticity care. During the in-person meeting the panel initially worked in small groups and then as whole to reach consensus through the Delphi process. The panel also completed a postsummit survey.
    Results: Several barriers to spasticity care and potentials solutions were identified. Consensus was reached for the top three barriers and potential solutions (>50% and >75%, respectively). Top barriers included the need for a document listing all the challenges related to access of care for spasticity, increased caregiver and community awareness of spasticity, and education of clinicians regarding patient needs. Top solutions to barriers included increasing the number of providers who treat spasticity, enhancing patient and caregiver education, and developing and publishing a consensus guidance statement.
    Conclusions: Consensus was achieved on the top three barriers to spasticity care and potential solutions. The purpose of this analysis is to pave the way for further development of solutions to improve the care of patients with spasticity.
    MeSH term(s) Humans ; United States ; Caregivers ; Health Services ; Muscle Spasticity/drug therapy ; Consensus ; Delphi Technique
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2608988-9
    ISSN 1934-1563 ; 1934-1482
    ISSN (online) 1934-1563
    ISSN 1934-1482
    DOI 10.1002/pmrj.13106
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Sleep apnoea in congestive heart failure: one step forwards.

    Patel, Sanjay R / Sykes, Alexandra V / Malhotra, Atul

    The Lancet. Respiratory medicine

    2023  Volume 12, Issue 2, Page(s) 94–96

    MeSH term(s) Humans ; Sleep Apnea Syndromes/complications ; Heart Failure/complications
    Language English
    Publishing date 2023-12-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(23)00377-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: A critical review on different roughness geometries and their effect on heat transfer and friction factor.

    Patel, Sumer Singh / Lanjewar, Atul

    Environmental science and pollution research international

    2022  Volume 29, Issue 11, Page(s) 15391–15431

    Abstract: Solar air heater (SAH) is simple and the greatest effective approach to utilize and convert solar energy into thermal energy for heating utilizations. The employment of artificial roughness under side of the observer surface is the key technique for ... ...

    Abstract Solar air heater (SAH) is simple and the greatest effective approach to utilize and convert solar energy into thermal energy for heating utilizations. The employment of artificial roughness under side of the observer surface is the key technique for augmenting heat transfer with minimal friction factor penalty. Current paper summarized different kinds of artificial roughness used in SAH, which augments its performance. In this review article, 96 research papers are cited, which provide detailed information about the effect of different geometrical parameters on heat transfer and friction factor. This paper also brings the information about the optimum roughness parameters and heat transfer and friction factor correlation developed by different investigators in tabular form. Optimum roughness parameters and empirical correlations are used for comparative analysis of heat transfer, friction factor, and thermo-hydraulic performance parameter (THPP) of different roughness geometries. The best performing roughness geometry is reported on the basis of comparative analysis. Mathematical model is developed for predicting the thermal efficiency (η
    MeSH term(s) Friction ; Hot Temperature ; Models, Theoretical ; Solar Energy ; Sunlight
    Language English
    Publishing date 2022-01-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-16298-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: A young female with fever, abdominal pain and eosinophilia.

    Patel, Atul K / Patel, Ketan K / Patel, Kamlesh

    Indian journal of medical microbiology

    2022  Volume 40, Issue 3, Page(s) 449–450

    Abstract: Fascioliasis has been reported from many countries across the globe. Acute phase of liver fluke is characterised by fever, abdominal pain and peripheral blood eosinophilia while the chronic phase is marked by chronic inflammation involving biliary tract. ...

    Abstract Fascioliasis has been reported from many countries across the globe. Acute phase of liver fluke is characterised by fever, abdominal pain and peripheral blood eosinophilia while the chronic phase is marked by chronic inflammation involving biliary tract. It is commonly diagnosed by a radiologist due to characteristic branching abscesses seen on CT scan, highly suggestive of liver fluke. Diagnosis is made by demonstration of eggs on direct microscopic examination of duodenal aspirate or bile. Screening of family members is recommended once diagnosis is has been made. Triclabendazole is the drug of choice for treatment.
    MeSH term(s) Abdominal Pain/drug therapy ; Abdominal Pain/etiology ; Animals ; Anthelmintics/therapeutic use ; Eosinophilia/diagnosis ; Eosinophilia/drug therapy ; Fasciola hepatica ; Fascioliasis/diagnosis ; Fascioliasis/drug therapy ; Female ; Fever/drug therapy ; Fever/etiology ; Humans ; Triclabendazole/therapeutic use
    Chemical Substances Anthelmintics ; Triclabendazole (4784C8E03O)
    Language English
    Publishing date 2022-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2022.07.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Characteristics and challenges of the clinical pipeline of digital therapeutics.

    Patel, Nisarg A / Butte, Atul J

    NPJ digital medicine

    2020  Volume 3, Issue 1, Page(s) 159

    Language English
    Publishing date 2020-12-11
    Publishing country England
    Document type Journal Article
    ISSN 2398-6352
    ISSN (online) 2398-6352
    DOI 10.1038/s41746-020-00370-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Fever in the returning traveler.

    Patel, Atul K / Shah, Kinjal / Chhipa, Deeksha / Patel, Dhaval / Patel, Ketan K

    Indian journal of medical microbiology

    2023  Volume 44, Page(s) 100368

    Abstract: Evaluation of febrile illness in a returning traveler is challenging as it requires careful history taking and knowledge of local epidemiology of endemic and epidemic diseases. Incorporating information of host characteristics for susceptibility of ... ...

    Abstract Evaluation of febrile illness in a returning traveler is challenging as it requires careful history taking and knowledge of local epidemiology of endemic and epidemic diseases. Incorporating information of host characteristics for susceptibility of infections is also important for endemic mycosis apart from history of tick bites and animal exposures. Laboratory tests directed by clinical and laboratory parameters will help to reach final diagnosis.
    MeSH term(s) Animals ; Travel ; Fever/diagnosis
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2023.100368
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Referral and Management of Pretibial Lacerations in Two District General Hospitals.

    Jefferies, Benjamin J / Patel, Lopa / Khanna, Atul

    Cureus

    2023  Volume 15, Issue 1, Page(s) e34231

    Abstract: Background Pretibial lacerations are common injuries that have a significant yet underestimated association with morbidity and mortality. Although they may occur in any age group, they are commonly followed by an often relatively minor trauma in elderly ... ...

    Abstract Background Pretibial lacerations are common injuries that have a significant yet underestimated association with morbidity and mortality. Although they may occur in any age group, they are commonly followed by an often relatively minor trauma in elderly and frail patients. The six-month mortality among such patients may be more than double the age group average. Currently, 5.2 in 1000 patients per year present to the emergency departments in UK hospitals due to pretibial lacerations. The associated acute admissions have a high financial cost. Despite the significant disease burden, there is a paucity of evidence on the optimal management of such injuries. This study aimed to describe the typical demographic and injury factors of individuals presenting to two district general hospitals, as well as their subsequent management and referral. Methodology Relevant patients were identified through NHS coding searches. Subsequently, it was found that 99 patients presented to an NHS trust with pretibial lacerations throughout 2020. A retrospective manual evaluation of clinical documentation was performed to identify the details of the patients' injury, management, referral, and demographics. Results The patients had a mean age of 55.4 (SD 28.3), and 56.6% were female. The most commonly presenting mechanism of injury was direct blunt trauma. The majority of cases were solely managed and discharged directly by the emergency department (74.8%). Of the 99 patients, 25 (25.3%) were referred to specialist services, 12 (12.1%) were managed conservatively, and 13 (13.1%) underwent operative intervention. The mean length of stay for those referred was 5.9 days, and the mean for the same was greater for those managed conservatively compared to those managed operatively (9.0 vs. 2.6 days). Among patients discharged by the emergency department, the most common method of wound closure was steristrips (n = 40; 54.1%), followed by conservative management with dressings (n = 22; 29.7%), sutures (n = 10, 13.5%) and glue (n = 5; 6.8%). Conclusions Overall, this study showed that the majority of patients presenting with pretibial lacerations have minor wounds that can be effectively managed in the emergency department. However, those with considerably more injuries should be provided an early referral to specialist services, where they would ideally receive early surgery and comprehensive follow-up.
    Language English
    Publishing date 2023-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34231
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: A critical review on different roughness geometries and their effect on heat transfer and friction factor

    Patel, Sumer Singh / Lanjewar, Atul

    Environmental science and pollution research. 2022 Mar., v. 29, no. 11

    2022  

    Abstract: Solar air heater (SAH) is simple and the greatest effective approach to utilize and convert solar energy into thermal energy for heating utilizations. The employment of artificial roughness under side of the observer surface is the key technique for ... ...

    Abstract Solar air heater (SAH) is simple and the greatest effective approach to utilize and convert solar energy into thermal energy for heating utilizations. The employment of artificial roughness under side of the observer surface is the key technique for augmenting heat transfer with minimal friction factor penalty. Current paper summarized different kinds of artificial roughness used in SAH, which augments its performance. In this review article, 96 research papers are cited, which provide detailed information about the effect of different geometrical parameters on heat transfer and friction factor. This paper also brings the information about the optimum roughness parameters and heat transfer and friction factor correlation developed by different investigators in tabular form. Optimum roughness parameters and empirical correlations are used for comparative analysis of heat transfer, friction factor, and thermo-hydraulic performance parameter (THPP) of different roughness geometries. The best performing roughness geometry is reported on the basis of comparative analysis. Mathematical model is developed for predicting the thermal efficiency (ηₜₕ) of roughened SAH duct.
    Keywords friction ; geometry ; heat transfer ; mathematical models ; pollution ; research ; roughness ; solar energy ; solar heaters ; thermal energy
    Language English
    Dates of publication 2022-03
    Size p. 15391-15431.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-16298-9
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top