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  1. Article ; Online: The potentially futile trauma transfer: "Should I Stay or Should I Go"?

    Romeo, Oreste Marco / Coccolini, Federico / Picetti, Edoardo

    The journal of trauma and acute care surgery

    2024  

    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2651070-4
    ISSN 2163-0763 ; 2163-0755
    ISSN (online) 2163-0763
    ISSN 2163-0755
    DOI 10.1097/TA.0000000000004257
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 127: Show issues Location:
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  2. Article ; Online: Pupillometry and sepsis-associated encephalopathy.

    Picetti, Edoardo / Robba, Chiara

    Minerva anestesiologica

    2022  Volume 88, Issue 5, Page(s) 332–333

    MeSH term(s) Humans ; Sepsis/complications ; Sepsis-Associated Encephalopathy
    Language English
    Publishing date 2022-05-05
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.22.16528-4
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    Zs.MO 192: Show issues

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  3. Article: Editorial: Intermittent feeding in critically ill patients.

    Deana, Cristian / Vecchiarelli, Pietro / Picetti, Edoardo / Molfino, Alessio

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1295405

    Language English
    Publishing date 2023-10-16
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1295405
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  4. Article ; Online: Craniectomy or Craniotomy for Acute Subdural Hematoma.

    Picetti, Edoardo / Taccone, Fabio Silvio / Robba, Chiara

    The New England journal of medicine

    2023  Volume 389, Issue 9, Page(s) 862–863

    MeSH term(s) Humans ; Hematoma, Subdural, Acute/diagnostic imaging ; Hematoma, Subdural, Acute/surgery ; Decompressive Craniectomy
    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2308428
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  5. Article ; Online: Preventing Futile Transfers of Patients with Intracerebral Hemorrhage.

    Picetti, Edoardo / Montanaro, Vito / Petranca, Massimo / Robba, Chiara

    Neurocritical care

    2022  Volume 38, Issue 1, Page(s) 208–209

    MeSH term(s) Humans ; Cerebral Hemorrhage/surgery ; Medical Futility
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Letter
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-022-01645-6
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    Zs.A 6538: Show issues Location:
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  6. Article ; Online: Non-invasive technology for brain monitoring: definition and meaning of the principal parameters for the International PRactice On TEChnology neuro-moniToring group (I-PROTECT).

    Romagnoli, Stefano / Lobo, Francisco A / Picetti, Edoardo / Rasulo, Frank A / Robba, Chiara / Matta, Basil

    Journal of clinical monitoring and computing

    2024  

    Abstract: Technologies for monitoring organ function are rapidly advancing, aiding physicians in the care of patients in both operating rooms (ORs) and intensive care units (ICUs). Some of these emerging, minimally or non-invasive technologies focus on monitoring ... ...

    Abstract Technologies for monitoring organ function are rapidly advancing, aiding physicians in the care of patients in both operating rooms (ORs) and intensive care units (ICUs). Some of these emerging, minimally or non-invasive technologies focus on monitoring brain function and ensuring the integrity of its physiology. Generally, the central nervous system is the least monitored system compared to others, such as the respiratory, cardiovascular, and renal systems, even though it is a primary target in most therapeutic strategies. Frequently, the effects of sedatives, hypnotics, and analgesics are entirely unpredictable, especially in critically ill patients with multiple organ failure. This unpredictability exposes them to the risks of inadequate or excessive sedation/hypnosis, potentially leading to complications and long-term negative outcomes. The International PRactice On TEChnology neuro-moniToring group (I-PROTECT), comprised of experts from various fields of clinical neuromonitoring, presents this document with the aim of reviewing and standardizing the primary non-invasive tools for brain monitoring in anesthesia and intensive care practices. The focus is particularly on standardizing the nomenclature of different parameters generated by these tools. The document addresses processed electroencephalography, continuous/quantitative electroencephalography, brain oxygenation through near-infrared spectroscopy, transcranial Doppler, and automated pupillometry. The clinical utility of the key parameters available in each of these tools is summarized and explained. This comprehensive review was conducted by a panel of experts who deliberated on the included topics until a consensus was reached. Images and tables are utilized to clarify and enhance the understanding of the clinical significance of non-invasive neuromonitoring devices within these medical settings.
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-024-01146-1
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    Zs.A 2054: Show issues Location:
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  7. Article ; Online: High Quality Targeted Temperature Management (TTM) After Cardiac Arrest.

    Taccone, Fabio Silvio / Picetti, Edoardo / Vincent, Jean-Louis

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 6

    Abstract: Targeted temperature management (TTM) is a complex intervention used with the aim of minimizing post-anoxic injury and improving neurological outcome after cardiac arrest. There is large variability in the devices used to achieve cooling and in protocols ...

    Abstract Targeted temperature management (TTM) is a complex intervention used with the aim of minimizing post-anoxic injury and improving neurological outcome after cardiac arrest. There is large variability in the devices used to achieve cooling and in protocols (e.g., for induction, target temperature, maintenance, rewarming, sedation, management of post-TTM fever). This variability can explain the limited benefits of TTM that have sometimes been reported. We therefore propose the concept of "high-quality TTM" as a way to increase the effectiveness of TTM and standardize its use in future interventional studies.
    MeSH term(s) Body Temperature ; Fever ; Heart Arrest ; Humans ; Hypothermia, Induced ; Temperature
    Language English
    Publishing date 2020-01-06
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-019-2721-1
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  8. Article ; Online: Perioperative management of severe brain injured patients.

    Picetti, Edoardo / Bouzat, Pierre / Cattani, Luca / Taccone, Fabio S

    Minerva anestesiologica

    2021  Volume 88, Issue 5, Page(s) 380–389

    Abstract: Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. Head injured patients may frequently require emergency neurosurgery. The perioperative TBI period is very important as many interventions done in this stage can have a ...

    Abstract Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. Head injured patients may frequently require emergency neurosurgery. The perioperative TBI period is very important as many interventions done in this stage can have a profound effect on the long-term neurological outcome. This practical concise narrative review focused mainly on: 1) the management of severe TBI patients with neurosurgical lesions admitted to a spoke center (i.e. hospital without neurosurgery) and therefore needing a transfer to the hub center (i.e. hospital with neurosurgery); 2) the management of severe TBI patients with intracranial hypertension/brain herniation awaiting for neurosurgery; and 3) the neuromonitoring-oriented management in the immediate post-operative period. The proposals presented in this review mainly apply to severe TBI patients admitted to high-income countries.
    MeSH term(s) Brain/physiopathology ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/surgery ; Brain Injuries, Traumatic/therapy ; Emergencies ; Humans ; Intracranial Hypertension/therapy ; Neurosurgery/methods ; Neurosurgery/standards ; Postoperative Care/methods ; Postoperative Care/standards ; Preoperative Care/methods ; Preoperative Care/standards
    Language English
    Publishing date 2021-10-12
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.21.15927-9
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    Zs.A 516: Show issues Location:
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    Zs.MO 192: Show issues

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  9. Article ; Online: The impact of muscle mass and myosteatosis on mortality in critically ill patients with Sars-Cov2-related pneumonia.

    Sabatino, Alice / Pacchiarini, Maria Chiara / Regolisti, Giuseppe / Ciuni, Andrea / Sverzellati, Nicola / Lesignoli, Matteo / Picetti, Edoardo / Fiaccadori, Enrico / Di Mario, Francesca

    Clinical nutrition ESPEN

    2023  Volume 58, Page(s) 409–415

    Abstract: Background & aims: Sars-Cov-2 pneumonia can lead to severe complications, requiring invasive mechanical ventilation and admission to the intensive care unit (ICU). Low muscle quantity and quality (the latter evaluated by the amount of ectopic fat ... ...

    Abstract Background & aims: Sars-Cov-2 pneumonia can lead to severe complications, requiring invasive mechanical ventilation and admission to the intensive care unit (ICU). Low muscle quantity and quality (the latter evaluated by the amount of ectopic fat infiltration in the muscle [myosteatosis]) at ICU admission are associated with worse outcomes in critically ill patients. The purpose of the present study is to assess muscle mass and myosteatosis of paravertebral skeletal muscle, in critically ill patients with Sars-Cov2 pneumonia and its association with mortality.
    Methods: We conducted a retrospective observational study in 110 critically ill patients with severe Sars-Cov-2 pneumonia that had a high - resolution chest Computerized Tomography (HR-CT) at ICU admission. We acquired CT images at the level of the thoracic 12 (T12) vertebral body and measured skeletal muscle area (SMA), intermuscular adipose tissue (IMAT), and low attenuation muscle area (LAMA). Patients were followed until ICU mortality or discharge.
    Results: Patients were 59.8 ± 8.1 years old, 77% were male. Seventy-nine percent of patients were considered at nutritional risk, and 22% were obese. Average Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 17 ± 5.4, and the overall ICU mortality was 48,2% (53/110). At ICU admission, both parameters of myosteatosis were associated with higher mortality (IMAT [per 10% increase] HR: 2.01 (95% Confidence Interval [CI] 1.27 to 3.17), P = 0.003; LAMA HR [per 10% increase]: 1.53 (95% CI 1.10 to 2.13), P = 0.012).
    Conclusion: Myosteatosis as assessed by CT scans plays a relevant role as a prognostic marker in critically ill patients with Sars-Cov2 severe pneumonia.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Female ; SARS-CoV-2 ; COVID-19 ; RNA, Viral ; Critical Illness ; Muscle, Skeletal/diagnostic imaging
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2023-11-11
    Publishing country England
    Document type Observational Study ; Journal Article
    ISSN 2405-4577
    ISSN (online) 2405-4577
    DOI 10.1016/j.clnesp.2023.11.006
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  10. Article ; Online: How to manage fever in brain-injured patients.

    Picetti, Edoardo / Minardi, Francesco / Rossi, Sandra

    Minerva anestesiologica

    2019  Volume 86, Issue 1, Page(s) 88–94

    Abstract: Fever represents a frequent and dangerous secondary insult for the injured brain and is often associated with worsened neurological outcomes. The identification of fever in the Neuro-Intensive Care Unit requires careful monitoring and rapid and effective ...

    Abstract Fever represents a frequent and dangerous secondary insult for the injured brain and is often associated with worsened neurological outcomes. The identification of fever in the Neuro-Intensive Care Unit requires careful monitoring and rapid and effective treatment. The main objective of this article was to provide practical information regarding temperature monitoring, triggers for intervention and fever management in brain injured patients.
    MeSH term(s) Brain Injuries/complications ; Brain Injuries/therapy ; Critical Care ; Disease Management ; Fever/etiology ; Fever/therapy ; Humans ; Monitoring, Physiologic ; Treatment Outcome
    Language English
    Publishing date 2019-09-13
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.19.13901-6
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