LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 46

Search options

  1. Article ; Online: The effect of treatment time, dialysis frequency, and ultrafiltration rate on intradialytic hypotension.

    Aronoff, George R

    Seminars in dialysis

    2017  Volume 30, Issue 6, Page(s) 489–491

    Abstract: Dialysis treatment time, the frequency of dialysis treatments, and the rate of fluid ultrafiltration-each impacts the incidence of intradialytic hypotension. These factors influence blood pressure independently and together. The strongest evidence ... ...

    Abstract Dialysis treatment time, the frequency of dialysis treatments, and the rate of fluid ultrafiltration-each impacts the incidence of intradialytic hypotension. These factors influence blood pressure independently and together. The strongest evidence supports that rapid ultrafiltration increases the likelihood of intradialytic hypotension and that combined strategies leading to a reduction in ultrafiltration rate have the greatest impact on reducing intradialytic hypotension. A practical approach to avoiding the effects of ultrafiltration on systemic hemodynamics would be to set a maximum ultrafiltration rate needed to achieve the desired fluid removal and vary the duration of the treatment to achieve that target volume. Randomized, controlled clinical trials of such strategies are warranted.
    MeSH term(s) Blood Volume/physiology ; Hemodynamics/physiology ; Humans ; Hypotension/etiology ; Kidney Failure, Chronic/therapy ; Renal Dialysis/adverse effects ; Renal Dialysis/methods ; Time Factors ; Ultrafiltration/adverse effects ; Ultrafiltration/methods
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1028193-9
    ISSN 1525-139X ; 0894-0959
    ISSN (online) 1525-139X
    ISSN 0894-0959
    DOI 10.1111/sdi.12625
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2879: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book: Drug prescribing in renal failure

    Aronoff, George R.

    dosing guidelines for adults

    1999  

    Author's details George R. Aronoff
    Keywords Pharmaceutical Preparations / administration & dosage ; Kidney Failure / drug therapy
    Language English
    Size 176 S.
    Edition 4. ed.
    Publisher American College of Physicians
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT010735925
    ISBN 0-943126-76-2 ; 978-0-943126-76-0
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 4294 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Telehealth monitoring decreases missed treatments in new dialysis patients.

    Reddy, Naveena / Aronoff, George R

    Nephrology news & issues

    2018  Volume 30, Issue 8, Page(s) 35–36

    MeSH term(s) Humans ; Quality of Health Care ; Renal Dialysis ; Telemedicine
    Language English
    Publishing date 2018-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1077629-1
    ISSN 1944-7493 ; 0896-1263
    ISSN (online) 1944-7493
    ISSN 0896-1263
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3266: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Drug prescribing in kidney disease: can't we do better?

    Aronoff, George R / Aronoff, Joel R

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2014  Volume 63, Issue 3, Page(s) 382–383

    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Female ; Humans ; Male ; Medication Errors ; Prescription Drugs/administration & dosage ; Renal Insufficiency, Chronic/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Prescription Drugs
    Language English
    Publishing date 2014-03
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2013.11.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 468: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Personalized Anemia Management and Precision Medicine in ESA and Iron Pharmacology in End-Stage Kidney Disease.

    Brier, Michael E / Gaweda, Adam E / Aronoff, George R

    Seminars in nephrology

    2018  Volume 38, Issue 4, Page(s) 410–417

    Abstract: Substantial progress has been made in the application of computer-driven methods to provide erythropoietic dosing information for patients with anemia resulting from chronic kidney disease. Initial solutions were simply computerized versions of ... ...

    Abstract Substantial progress has been made in the application of computer-driven methods to provide erythropoietic dosing information for patients with anemia resulting from chronic kidney disease. Initial solutions were simply computerized versions of traditional paper-based anemia management protocols. True personalization was achieved through the use of advanced modeling techniques such as artificial neural networks, physiologic models, and feedback control systems. The superiority of any one technique over another has not been determined, but all methods have shown an advantage in at least one area over the traditional paper expert system used by most dialysis facilities. Improvements in the percentage of hemoglobin measurements within target range, decreased within-subject hemoglobin variability, decreased erythropoiesis-stimulating agent dose, and decreased transfusion rates all have been shown.
    MeSH term(s) Anemia/drug therapy ; Anemia/etiology ; Hematinics/administration & dosage ; Hematinics/pharmacokinetics ; Hemoglobins/metabolism ; Humans ; Iron/administration & dosage ; Iron/pharmacokinetics ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/metabolism ; Kidney Failure, Chronic/therapy ; Models, Biological ; Neural Networks (Computer) ; Precision Medicine ; Renal Dialysis ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/metabolism ; Renal Insufficiency, Chronic/therapy
    Chemical Substances Hematinics ; Hemoglobins ; Iron (E1UOL152H7)
    Language English
    Publishing date 2018-08-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2018.05.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Se 784: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Balancing ESA and iron therapy in a prospective payment environment.

    Aronoff, George R / Gaweda, Adam E

    Nephrology news & issues

    2014  Volume 28, Issue 2, Page(s) 16–18

    Abstract: Ever since the introduction of EPO, ESAs and iron dosing have been driven by financial incentives. When ESAs were a profit center for providers, large doses were used. With ESAs becoming a cost center, a new trend has appeared, gradually replacing their ... ...

    Abstract Ever since the introduction of EPO, ESAs and iron dosing have been driven by financial incentives. When ESAs were a profit center for providers, large doses were used. With ESAs becoming a cost center, a new trend has appeared, gradually replacing their use with iron to achieve the same therapeutic effect at lower cost. This financially driven approach, treating ESAs and iron as alternatives, is not consistent with human physiology where these agents act in a complementary manner. It is likely that we are still giving unnecessarily large doses of ESAs and iron, relative to what our patients' true needs are. Although we have highlighted the economic drivers of this outcome, many other factors play a role. These include our lack of understanding of the complex interplay of the anemia of chronic disease, inflammation, poor nutrition, blood loss through dialysis, ESAs and iron deficiency. We propose that physiology-driven modeling may provide some insight into the interactions between erythropoiesis and ferrokinetics. This insight can then be used to derive new, physiologically compatible dosing guidelines for ESAs and iron.
    MeSH term(s) Anemia, Iron-Deficiency/drug therapy ; Anemia, Iron-Deficiency/economics ; Anemia, Iron-Deficiency/etiology ; Erythropoietin/economics ; Erythropoietin/therapeutic use ; Hematinics/economics ; Hematinics/therapeutic use ; Humans ; Iron/economics ; Iron/therapeutic use ; Prospective Payment System/economics ; Renal Dialysis ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/economics
    Chemical Substances Hematinics ; Erythropoietin (11096-26-7) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2014-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1077629-1
    ISSN 1944-7493 ; 0896-1263
    ISSN (online) 1944-7493
    ISSN 0896-1263
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3266: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: The medical director in integrated clinical care models.

    Parker, Thomas F / Aronoff, George R

    Clinical journal of the American Society of Nephrology : CJASN

    2014  Volume 10, Issue 7, Page(s) 1282–1286

    Abstract: Integrated clinical care models, like Accountable Care Organizations and ESRD Seamless Care Organizations, present new opportunities for dialysis facility medical directors to affect changes in care that result in improved patient outcomes. Currently, ... ...

    Abstract Integrated clinical care models, like Accountable Care Organizations and ESRD Seamless Care Organizations, present new opportunities for dialysis facility medical directors to affect changes in care that result in improved patient outcomes. Currently, there is little scholarly information on what role the medical director should play. In this opinion-based review, it is predicted that dialysis providers, the hospitals in which the medical director and staff physicians practice, and the payers with which they contract are going to insist that, as care becomes more integrated, dialysis facility medical directors participate in new ways to improve quality and decrease the costs of care. Six broad areas are proposed where dialysis unit medical directors can have the greatest effect on shifting the quality-care paradigm where integrated care models are used. The medical director will need to develop an awareness of the regional medical care delivery system, collect and analyze actionable data, determine patient outcomes to be targeted that are mutually agreed on by participating physicians and institutions, develop processes of care that result in improved patient outcomes, and lead and inform the medical staff. Three practical examples of patient-centered, quality-focused programs developed and implemented by dialysis unit medical directors and their practice partners that targeted dialysis access, modality choice, and fluid volume management are presented. Medical directors are encouraged to move beyond traditional roles and embrace responsibilities associated with integrated care.
    MeSH term(s) Accountable Care Organizations/organization & administration ; Accountable Care Organizations/standards ; Delivery of Health Care, Integrated/organization & administration ; Delivery of Health Care, Integrated/standards ; Humans ; Job Description ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/physiopathology ; Kidney Failure, Chronic/therapy ; Models, Organizational ; Patient Care Team/organization & administration ; Patient Care Team/standards ; Physician Executives/organization & administration ; Physician Executives/standards ; Process Assessment, Health Care ; Professional Role ; Quality Improvement ; Quality Indicators, Health Care ; Renal Dialysis/standards ; Treatment Outcome
    Language English
    Publishing date 2014-10-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.05120514
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6584: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Individualized anemia management in a dialysis facility - long-term utility as a single-center quality improvement experience
.

    Gaweda, Adam E / Jacobs, Alfred A / Aronoff, George R / Brier, Michael E

    Clinical nephrology

    2018  Volume 90, Issue 4, Page(s) 276–285

    Abstract: Background: Standard protocol-based approaches to erythropoiesis stimulating agent (ESA) dosing in anemia management of end-stage renal disease (ESRD) fail to address the inter-individual variability in patient's response to ESA. We conducted a single- ... ...

    Abstract Background: Standard protocol-based approaches to erythropoiesis stimulating agent (ESA) dosing in anemia management of end-stage renal disease (ESRD) fail to address the inter-individual variability in patient's response to ESA. We conducted a single-center quality improvement project to investigate the long-term performance of a computer-designed dosing system.
    Materials and methods: The study was a retrospective case-control study with long-term follow-up. All hemodialysis patients who received treatment at University Kidney Center (Louisville, KY, USA) between September 1, 2009, and March 31, 2017, were included. We implemented an individualized ESA dosing algorithm into an electronic health records database software to provide patient-specific ESA dose recommendations to anemia managers at monthly intervals. The primary outcome was the percentage of hemoglobin (Hb) concentrations between 10 and 12 g/dL during the case-control study and 9 and 11 g/dL during follow-up. Secondary outcomes were intra- and inter-individual Hb variability. For the case-control study, we compared outcomes over 12 months before and after implementation of the algorithm. Subjects served as their own controls. We used the last Hb concentration of the month and ESA dose per week. Long-term follow-up examined trends in proportion within the target range, Hb, and ESA dose.
    Results: Individualized ESA dosing in 56 subjects was associated with a moderate (6.6%) increase of mean Hb maintenance within target over the 12-month observation period (62.7% before vs. 69.3% after, p = 0.063). Intra-individual mean Hb variability decreased (1.1 g/dL before vs. 0.8 g/dL after, p < 0.001), so did inter-individual mean Hb variability (1.2 g/dL before vs. 1.0 g/dL after, p = 0.010). Long-term follow-up in 233 subjects for 42 months demonstrated stability of the achieved Hb despite an increasing ESA resistance in the patient population.
    Conclusion: Implementation of the individualized ESA dosing algorithm facilitates improvement in Hb maintenance within target, decreases Hb variability and reduces the dose of ESA required to achieve Hb target.
.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Algorithms ; Ambulatory Care Facilities ; Anemia/blood ; Anemia/drug therapy ; Anemia/etiology ; Case-Control Studies ; Drug Therapy, Computer-Assisted ; Electronic Health Records ; Female ; Follow-Up Studies ; Hematinics/administration & dosage ; Hematinics/therapeutic use ; Hemoglobins/metabolism ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Quality Improvement ; Renal Dialysis/adverse effects ; Retrospective Studies ; Software ; Time Factors
    Chemical Substances Hematinics ; Hemoglobins
    Language English
    Publishing date 2018-07-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185101-9
    ISSN 0301-0430
    ISSN 0301-0430
    DOI 10.5414/CN109499
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 873: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: The first 120 days of crucial care: Strategies for managing incident dialysis patients.

    Reddy, Naveena / Sukheswalla, Farzeen / Aronoff, George R

    Nephrology news & issues

    2015  Volume 29, Issue 8, Page(s) 27–31

    MeSH term(s) Continuity of Patient Care/organization & administration ; Humans ; Incidence ; Kidney Failure, Chronic/mortality ; Kidney Failure, Chronic/therapy ; Patient Education as Topic ; Quality of Life ; Renal Dialysis ; United States
    Language English
    Publishing date 2015-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1077629-1
    ISSN 1944-7493 ; 0896-1263
    ISSN (online) 1944-7493
    ISSN 0896-1263
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3266: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Dose adjustment in renal impairment: response from Drug Prescribing in Renal Failure.

    Aronoff, George R

    BMJ (Clinical research ed.)

    2005  Volume 331, Issue 7511, Page(s) 293–294

    MeSH term(s) Humans ; Kidney Diseases ; Pharmaceutical Preparations/administration & dosage ; Reference Books/standards ; United Kingdom
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2005-07-30
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.331.7511.293-a
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.10: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top