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  1. Book ; Online: Advances in Transoral Approaches for Laryngeal Cancer

    Piazza, Cesare / Peretti, Giorgio / Vander Poorten, Vincent

    2019  

    Keywords Medicine ; Oncology ; Laryngeal cancer ; Salvage Surgery ; Transoral laser microsurgery ; Squamous cell carcinoma ; transoral robotic surgery ; Supraglottic partial laryngectomy ; Organ preservation surgery ; Laryngeal imaging ; Oncologic outcomes ; prognosis
    Size 1 electronic resource (111 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021229868
    ISBN 9782889457779 ; 288945777X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Editorial: Oral Oncology: From Precise Surgery to Precision Medicine and Surgery.

    Saidak, Zuzana / Piazza, Cesare

    Frontiers in oral health

    2022  Volume 3, Page(s) 913172

    Language English
    Publishing date 2022-04-28
    Publishing country Switzerland
    Document type Editorial
    ISSN 2673-4842
    ISSN (online) 2673-4842
    DOI 10.3389/froh.2022.913172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Head and neck nonmelanoma skin cancers: surgical management and debated issues.

    Rampinelli, Vittorio / Pinacoli, Aurora / Piazza, Cesare

    Current opinion in otolaryngology & head and neck surgery

    2024  Volume 32, Issue 2, Page(s) 62–70

    Abstract: Purpose of review: This review critically assesses the current literature and guidelines, aiming to clarify some of the most important factors that impact surgical strategies of head and neck nonmelanoma skin cancers (NMSCs), focusing on squamous, basal, ...

    Abstract Purpose of review: This review critically assesses the current literature and guidelines, aiming to clarify some of the most important factors that impact surgical strategies of head and neck nonmelanoma skin cancers (NMSCs), focusing on squamous, basal, and Merkel cell carcinomas.
    Recent findings: Recent developments underscore the complexity of treatment for NMSC, particularly in the head and neck region. There is a lack of high-level evidence for the management of these tumors, especially in advanced stages. The need to tailor the extent of surgical margins and parotid/neck management to different histotypes, considering the varying risk factors for recurrence, is beginning to emerge in the literature. Moreover, the role of immunotherapy and targeted therapies for locally advanced disease, alongside traditional treatment options, is progressively growing.
    Summary: NMSCs represent a heterogeneous group of malignancies with varying treatment complexities and prognoses. Management of NMSC is evolving towards an increasingly personalized strategy within a multidisciplinary therapeutic framework.
    MeSH term(s) Humans ; Carcinoma, Basal Cell/pathology ; Carcinoma, Basal Cell/surgery ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology ; Prognosis ; Head and Neck Neoplasms/surgery ; Immunotherapy
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Compartmental surgery for T4b oral squamous cell carcinoma involving the masticatory space.

    Mattavelli, Davide / Montenegro, Claudia / Piazza, Cesare

    Current opinion in otolaryngology & head and neck surgery

    2024  Volume 32, Issue 2, Page(s) 55–61

    Abstract: Purpose of review: This review aims to describe the oncological outcomes of T4b oral squamous cell carcinomas (OSCC) with masticatory space involvement as well as the surgical approaches that are able to achieve compartmental 'en bloc' resection of ... ...

    Abstract Purpose of review: This review aims to describe the oncological outcomes of T4b oral squamous cell carcinomas (OSCC) with masticatory space involvement as well as the surgical approaches that are able to achieve compartmental 'en bloc' resection of these lesions.
    Recent findings: The masticatory space is subdivided into infra-notch and supra-notch spaces according to the axial plane passing through the mandibular notch between the coronoid process and the condyle neck. Compartmental resection for T4b OSCC with masticatory space invasion can be successfully achieved via purely external approaches or combining external and transnasal endoscopic routes. Infra-notch T4b OSCC showed survival outcomes comparable to T4a OSCC, thus prompting treatment with curative intent.
    Summary: Compartmental resection of the masticatory space is technically feasible with comprehensive control of tumour margins. Use of a transnasal endoscopic anterior route within a multiportal approach may provide better control of margins at the level of the pterygo-maxillary fissure. Equivalent survival outcomes between T4a and infra-notch T4b OSCC are reported. Thus, a downstaging of the latter to T4a is advisable and compartmental surgery of such advanced lesions could be considered as a first-line treatment option in selected patients.
    MeSH term(s) Humans ; Mouth Neoplasms/surgery ; Mouth Neoplasms/pathology ; Squamous Cell Carcinoma of Head and Neck/surgery ; Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000958
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial

    Zuzana Saidak / Cesare Piazza

    Frontiers in Oral Health, Vol

    Oral Oncology: From Precise Surgery to Precision Medicine and Surgery

    2022  Volume 3

    Keywords oral oncology ; precision surgery ; precise surgery ; precision medicine ; personalized treatment ; Dentistry ; RK1-715
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Measuring financial toxicity in head and neck cancer: a systematic review.

    Raggini, Elisa / Mattavelli, Davide / Zigliani, Gabriele / Bossi, Paolo / Piazza, Cesare

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2024  Volume 44, Issue 1, Page(s) 1–12

    Abstract: Objective: The current study systematically reviews the literature about financial toxicity (FT) in head and neck cancer patients. Three databases were reviewed: PubMed, Scopus and Web of Science.: Methods: Full text English papers published from ... ...

    Abstract Objective: The current study systematically reviews the literature about financial toxicity (FT) in head and neck cancer patients. Three databases were reviewed: PubMed, Scopus and Web of Science.
    Methods: Full text English papers published from 2000 to 2022 reporting on quantitative results about FT in head and neck cancer survivors collected through structured questionnaires or interviews were included.
    Results: Twenty-seven articles were included. Most of the articles were published after 2015 and from United States. There was a slight prevalence of papers dealing with oropharyngeal cancer, squamous-cell carcinoma and locally advanced head and neck cancer. Measures of FT were obtained through validated questionnaires like COST, FIT and FDQ. Collected data were mostly referrable to financial spending, financial resources, psychosocial aspect, support seeking, coping care and coping lifestyle subdomain. FT scores by COST were found to be worse in the COVID era. Financial counseling and adequate information about the costs of treatment were two effective strategies to mitigate FT.
    Conclusions: FT is a relatively new challenge in head and neck cancer treatment, whose expenses are higher than therapies for other cancers. A universal method to assess FT and a unified guideline for the administration of questionnaires are needed to mitigate FT and to improve patient outcomes.
    MeSH term(s) Humans ; Financial Stress ; Head and Neck Neoplasms/economics ; Oropharyngeal Neoplasms/economics ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2024-02-14
    Publishing country Italy
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N2762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2608: Show issues Location:
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  7. Article ; Online: Cervical exenteration and its variants for locally advanced thyroid cancer: when, why, and how?

    Piazza, Cesare / Lancini, Davide / Paderno, Alberto

    Current opinion in otolaryngology & head and neck surgery

    2023  Volume 31, Issue 2, Page(s) 65–72

    Abstract: Purpose of review: To describe the modern surgical approach for management of advanced thyroid cancers infiltrating the cervicovisceral axis with special attention to well differentiated tumors not amenable to organ-sparing techniques. In particular, ... ...

    Abstract Purpose of review: To describe the modern surgical approach for management of advanced thyroid cancers infiltrating the cervicovisceral axis with special attention to well differentiated tumors not amenable to organ-sparing techniques. In particular, cervical exenteration, herein defined as the sum of total thyroidectomy, central compartment and lateral neck dissections, variously associated with total laryngectomy and possible partial or total pharyngoesophagectomy, represents an extreme surgical procedure that, in properly selected cases, allows for reasonable palliation of central compartment life-threatening signs/symptoms if not cure for an advanced oncologic condition.
    Recent findings: Cervical exenteration is not contraindicated by the presence of limited distant metastases at presentation. Even though it requires that the patient is in general good health as it can be associated with a number of complications and long in-hospital stay, when appropriately planned and performed according to the most recent reconstructive nuances, it allows good oncologic outcomes that are not inferior to those described for similarly advanced primaries of the upper aerodigestive tract. In addition, quality of life and functional results are not significantly different from those described after total laryngectomy for primary laryngeal squamous cell carcinomas.
    Summary: Cervical exenteration requires a tertiary, expert, multidisciplinary effort in terms of diagnosis, surgical performance, and postoperative care. A patient-centered decision process is strongly warranted taking into consideration alternative therapeutic and symptom-based palliative strategies.
    MeSH term(s) Humans ; Quality of Life ; Thyroid Neoplasms/pathology ; Thyroidectomy/methods ; Neck Dissection
    Language English
    Publishing date 2023-01-28
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial: Advances in the Multidisciplinary Management of Oral Cancer.

    Paderno, Alberto / Bossi, Paolo / Piazza, Cesare

    Frontiers in oncology

    2021  Volume 11, Page(s) 817756

    Language English
    Publishing date 2021-12-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.817756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Is the exoscope ready to replace the operative microscope in transoral surgery?

    Paderno, Alberto / Deganello, Alberto / Lancini, Davide / Piazza, Cesare

    Current opinion in otolaryngology & head and neck surgery

    2022  Volume 30, Issue 2, Page(s) 79–86

    Abstract: Purpose of review: Exoscopes are external digital devices that provide enhanced and magnified visualization of the surgical field. They usually have dedicated digital controls and a more compact mechanical structure than operative microscopes and ... ...

    Abstract Purpose of review: Exoscopes are external digital devices that provide enhanced and magnified visualization of the surgical field. They usually have dedicated digital controls and a more compact mechanical structure than operative microscopes and current robotic surgical systems. This technology has significant potential in otolaryngology - head and neck surgery, especially concerning the field of transoral approaches. We herein analysed the overall technical characteristics of currently available exoscopic systems and contextualized their advantages and drawbacks in the setting of transoral surgery.
    Recent findings: The actual advantages of exoscopy are still indeterminate, as it has only been applied to limited surgical series. However, its specific properties are herein compared with conventional transoral microsurgery and transoral robotic surgery, discussing the available literature on such a topic, filtered on the basis of the authors' experience and its possible future evolutions. Finally, a summary of current experiences in the field of three-dimensional (3D) transoral exoscopic surgery is presented, highlighting differences compared with standard approaches.
    Summary: 3D-exoscopic transoral surgery will possibly play an essential role in future management of early laryngeal and oropharyngeal lesions, significantly shifting the paradigms of this type of procedures.
    MeSH term(s) Humans ; Microsurgery/methods ; Robotic Surgical Procedures
    Language English
    Publishing date 2022-02-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000794
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  10. Article ; Online: Head and neck squamous cell carcinoma in HIV patients.

    Rampinelli, Vittorio / Gennarini, Francesca / Borsetto, Daniele / Piazza, Cesare

    Current opinion in otolaryngology & head and neck surgery

    2022  Volume 31, Issue 2, Page(s) 78–82

    Abstract: Purpose of review: The introduction of antiretroviral therapy has significantly impacted the incidence of head and neck squamous cell carcinoma (HNSCC) in people living with HIV (PLWH). This manuscript aims to give an overview of the evidence in the ... ...

    Abstract Purpose of review: The introduction of antiretroviral therapy has significantly impacted the incidence of head and neck squamous cell carcinoma (HNSCC) in people living with HIV (PLWH). This manuscript aims to give an overview of the evidence in the literature about this population.
    Recent findings: PLWH have an increased incidence of HNSCC, with earlier age and more advanced stage at diagnosis. This epidemiologic trend may be explained by combining traditional and HIV-related risk factors. With the improvement of global health status, more patients are candidate for complex therapeutic strategies with curative intent. To date, it is still debated whether HIV-infected patients possess a profile of increased risk regarding treatment-related toxicity and survival outcomes, with the literature still lacking substantial evidence. Among the prognostic factors that can guide the clinician in selecting the most appropriate treatment strategy, age, site/subsite, stage, HIV viral load, and CD4+ T-cell count at diagnosis are the most relevant.
    Summary: Pathogenesis, treatment characteristics, oncologic outcomes, and prognostic factors of HNSCC in PLWH are still debated. Given the increasing incidence of HNSCC in PLWH, the need for dedicated evidence-based studies represents a significant research gap to be addressed.
    MeSH term(s) Humans ; Squamous Cell Carcinoma of Head and Neck ; Head and Neck Neoplasms ; HIV Infections ; Carcinoma, Squamous Cell/pathology ; Incidence
    Language English
    Publishing date 2022-12-27
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000868
    Database MEDical Literature Analysis and Retrieval System OnLINE

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