Article ; Online: Sarcoidosis of the pancreas mimicking adenocarcinoma.
BMJ case reports
2013 Volume 2013
Abstract: Primary sarcoidosis of the pancreas is extremely rare. Clinical presentation is often identical to that of pancreatic adenocarcinoma. Preoperative diagnosis of primary pancreatic sarcoidosis is always challenging. We present a 52-year-old man who ... ...
Abstract | Primary sarcoidosis of the pancreas is extremely rare. Clinical presentation is often identical to that of pancreatic adenocarcinoma. Preoperative diagnosis of primary pancreatic sarcoidosis is always challenging. We present a 52-year-old man who developed weight loss and obstructive jaundice. Abdomino-pelvic CT scan showed a mass in the pancreatic head. After hepatopancreaticobiliary MDT discussion, a Whipple's procedure was attempted but the mass was deemed unresectable due to invasion of the superior mesenteric vein. Upon completion of palliative chemotherapy, repeat imaging showed significant mass shrinkage. A reattempt Whipple's procedure was successfully undertaken. Histology showed changes of chronic pancreatitis and peripancreatic granulomatous inflammation with no evidence of malignancy and a diagnosis of sarcoidosis was made. Owing to the devastating nature of pancreatic adenocarcinoma, any mass in the pancreas must be thoroughly investigated before a definitive diagnosis is made. |
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MeSH term(s) | Adenocarcinoma/diagnosis ; Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/physiopathology ; Adult ; Aged ; Combined Modality Therapy ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Pancreatic Diseases/diagnosis ; Pancreatic Diseases/diagnostic imaging ; Pancreatic Diseases/physiopathology ; Pancreatic Diseases/therapy ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/physiopathology ; Sarcoidosis/diagnosis ; Sarcoidosis/diagnostic imaging ; Sarcoidosis/physiopathology ; Sarcoidosis/therapy ; Tomography, X-Ray Computed |
Language | English |
Publishing date | 2013-06-19 |
Publishing country | England |
Document type | Case Reports ; Journal Article |
ISSN | 1757-790X |
ISSN (online) | 1757-790X |
DOI | 10.1136/bcr-2013-009118 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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