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  1. Article ; Online: Safety of del Nido cardioplegia during frozen elephant trunk procedure: A case report of first experience in complex aortic surgery.

    Comentale, Giuseppe / Pilato, Emanuele

    Perfusion

    2023  , Page(s) 2676591231157202

    Abstract: We report the case of a 74 years-old male who underwent frozen elephant trunk due to a huge aortic arch aneurysm related to a type 1A endoleak after thoracic endovascular aortic repair where cardioplegic arrest was achieved using the Del Nido ... ...

    Abstract We report the case of a 74 years-old male who underwent frozen elephant trunk due to a huge aortic arch aneurysm related to a type 1A endoleak after thoracic endovascular aortic repair where cardioplegic arrest was achieved using the Del Nido cardioplegia.
    Language English
    Publishing date 2023-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591231157202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2424: Show issues Location:
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  2. Article ; Online: Single-chamber leadless endocardial pacing in last-generation centrifugal-flow left ventricle assist devices: a case report.

    Loforte, Antonio / Ziacchi, Matteo / Comentale, Giuseppe / Piemontese, Giuseppe Pio / Gliozzi, Gregorio / Suarez, Sofia Martin / Biffi, Mauro / Pacini, Davide

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 6, Page(s) 361–364

    MeSH term(s) Humans ; Heart Ventricles ; Pacemaker, Artificial ; Cardiac Pacing, Artificial ; Equipment Design
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5210: Show issues Location:
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  3. Article: Asymptomatic giant ascending aortic aneurysm: a challenging surgical strategy for a silent bicuspid aortopathy.

    Romeo, Maria Grazia / Pilato, Emanuele / Giordano, Raffaele / Comentale, Giuseppe / Iannelli, Gabriele / Romeo, Domenico / Miserrafiti, Bruna / Di Tommaso, Luigi

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2024  

    Abstract: We report the case of an incidental finding of a huge aneurysm of the ascending aorta with a congenital bicuspid aortic valve type 0-lateral. This severe condition was totally unknown to the patient, who was asymptomatic for cardiovascular disease. The ... ...

    Abstract We report the case of an incidental finding of a huge aneurysm of the ascending aorta with a congenital bicuspid aortic valve type 0-lateral. This severe condition was totally unknown to the patient, who was asymptomatic for cardiovascular disease. The aneurysmal mass involved the entire mediastinum, altering the normal anatomical relations, so the operative strategy was modified intraoperatively, tailoring the surgical technique to the anatomical conditions found. Despite a delayed awakening, the patient had an uncomplicated postoperative course. Therefore, this case highlights the importance of not underestimating nonspecific, seemingly harmless symptoms and signs that may reveal potentially catastrophic pathologies, while also focusing on the surgical technique used. The modified Cabrol procedure, while an underutilized technique, if present in the cardiac surgeon's "arsenal," can represent a life-saving strategy in complex cases requiring an aortic valve and ascending aorta replacement.
    Language English
    Publishing date 2024-03-18
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2024.2936
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    Zs.B 65: Show issues Location:
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  4. Article ; Online: Individual patient data meta-analysis on awake pediatric extracorporeal life support: Feasibility and safety of analgesia, sedation and respiratory support weaning, and physiotherapy.

    Cucchi, Marta / Mariani, Silvia / Kawczynski, Michal J / Shkurka, Emma / Ius, Fabio / Comentale, Giuseppe / Hoskote, Aparna / Lorusso, Roberto

    Perfusion

    2024  , Page(s) 2676591241240377

    Abstract: Objective: Awake Extracorporeal Life Support (aECLS) with active mobilization has gained consensus over time, also within the pediatric community. This individual patient data (IPD) meta-analysis summarizes available evidence on pediatric aECLS, its ... ...

    Abstract Objective: Awake Extracorporeal Life Support (aECLS) with active mobilization has gained consensus over time, also within the pediatric community. This individual patient data (IPD) meta-analysis summarizes available evidence on pediatric aECLS, its feasibility, and safety regarding sedation weaning, extubation, and physiotherapy.
    Methods: PubMed/Medline and Cochrane Database were screened until February 2022. Articles reporting on children (≤18 years) undergoing aECLS were selected. IPD were requested, pooled in a single database, and analyzed using descriptive statistics. Primary outcome was survival to hospital discharge. Secondary outcomes included extubation during ECLS, physiotherapy performed, tracheostomy, and complications.
    Results: Nineteen articles and 65 patients (males:
    Conclusion: Awake ECLS strategy with active physiotherapy can be applied in children from neonatal age. Ambulation is also possible in selected cases. Complications related to such management were limited. Further studies on aECLS are needed to evaluate safety and efficacy of early physiotherapy and define patient selection.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591241240377
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  5. Article ; Online: Sars-Cov-2 infection as a possible risk factor for prosthesis endocarditis: A challenging redo-Bentall for subvalvular abscess.

    Romeo, Maria Grazia / Comentale, Giuseppe / Cirillo, Vera / Pilato, Emanuele

    Journal of cardiac surgery

    2022  Volume 37, Issue 9, Page(s) 2845–2848

    Abstract: Background: Candida Parapsilosis is an unusual agent of prosthetic endocarditis in immunocompetent individuals but Coronavirus disease 2019 is reported to be associated with a transient immunodeficency that exposes patientes to opportunistic infections.! ...

    Abstract Background: Candida Parapsilosis is an unusual agent of prosthetic endocarditis in immunocompetent individuals but Coronavirus disease 2019 is reported to be associated with a transient immunodeficency that exposes patientes to opportunistic infections.
    Case report: We describe a dreadful case of Candida Parapsilosis endocarditis in a transient immunosuppressed patient recently infected with severe acute respiratory syndrome-Coronavirus 2019.
    Conclusion: Considering that the symptoms of Candida Parapsilosis infection and the symptoms of Coronavirus disease-2019 may overlap, it is important never to understimate the non-specific symptoms to improve patient outcome, especially in patient with previous Coronavirurs disease-2019 infection and with prosthetic material grafting.
    MeSH term(s) Abscess/etiology ; Abscess/microbiology ; Abscess/surgery ; COVID-19/complications ; COVID-19/immunology ; Candida parapsilosis/isolation & purification ; Candidiasis/etiology ; Candidiasis/microbiology ; Endocarditis/etiology ; Endocarditis/microbiology ; Endocarditis/surgery ; Heart Valve Prosthesis/adverse effects ; Heart Valve Prosthesis/microbiology ; Humans ; Immunocompromised Host ; Reoperation ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2022-06-25
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.16729
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    Zs.A 2221: Show issues Location:
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  6. Article ; Online: Impact of preoperative left pulmonary artery stenting on the Fontan procedure: a retrospective multicentre study.

    Comentale, Giuseppe / Cucchi, Marta / Serrao, Andrea / Careddu, Lucio / Napoleone, Carlo Pace / Gargiulo, Gaetano / Oppido, Guido

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  Volume 65, Issue 2

    Abstract: Objectives: Left pulmonary artery (LPA) or bifurcation stenoses at Fontan palliation can be very challenging to treat and may also require cardioplegia and aortic transection. Moreover, the low pressure of Fontan circulation and the bulkiness of the ... ...

    Abstract Objectives: Left pulmonary artery (LPA) or bifurcation stenoses at Fontan palliation can be very challenging to treat and may also require cardioplegia and aortic transection. Moreover, the low pressure of Fontan circulation and the bulkiness of the aorta increase the risk of a patch angioplasty collapse. Pre-Fontan LPA stenting of stenotic LPAs overcomes those drawbacks therefore the present study aimed to evaluate its advantageous impact on Fontan surgery.
    Methods: A multicentre retrospective analysis was performed on 304 consecutive Fontan patients. The study population was divided into 2 groups (LPA stented, n = 62 vs not stented, n = 242); pre-and postoperative data were compared.
    Results: LPA-stented patients had a higher prevalence of systemic right ventricle (P = 0.01), hypoplastic left heart syndrome (P = 0.042), complex neonatal palliations (Norwood/Damus-Kaye-Stansel) and surgical LPA patch repair at Glenn (P < 0.001). No differences were found in cross-clamp rates, early (P = 0.29) and late survival (94.6% vs 98.4, P = 0.2) or complications (P = 0.14). Complex palliations on ascending aorta/aortic arch (P = 0.013) and surgical LPA repair at Glenn (P < 0.001) proved to be risk factors for LPA stenting before Fontan at multivariable analysis.
    Conclusions: The LPA-stented group showed similar outcomes in terms of survival and complications rate compared to patients without LPA stenosis; however, they significantly differ in their higher preoperative risk profile and in their more complex anatomy. Complex neonatal palliations involving ascending aorta or aortic arch may increase the risk of pulmonary branches stenosis requiring stenting; therefore, preoperative stenting of LPA stenoses could help to reduce the surgical risk of complex Fontan procedure by avoiding the need for cross-clamp or complex mediastinal dissections to perform a high-risk surgical repair.
    MeSH term(s) Infant, Newborn ; Humans ; Infant ; Pulmonary Artery/surgery ; Constriction, Pathologic ; Retrospective Studies ; Treatment Outcome ; Fontan Procedure/adverse effects ; Hypoplastic Left Heart Syndrome/surgery ; Heart Ventricles/surgery
    Language English
    Publishing date 2024-02-03
    Publishing country Germany
    Document type Multicenter Study ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezae035
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    Zs.A 2303: Show issues Location:
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  7. Article: Mechanical circulatory supports after pulmonary thrombo-endarterectomy: why, when and how.

    Loforte, Antonio / Comentale, Giuseppe / Gliozzi, Gregorio / Cavalli, Giulio Giovanni / Pacini, Davide / Martin-Suarez, Sofia

    Annals of cardiothoracic surgery

    2022  Volume 11, Issue 2, Page(s) 169–171

    Language English
    Publishing date 2022-03-19
    Publishing country China
    Document type Editorial
    ZDB-ID 2713627-9
    ISSN 2304-1021 ; 2225-319X
    ISSN (online) 2304-1021
    ISSN 2225-319X
    DOI 10.21037/acs-2021-pte-16
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  8. Article ; Online: Pulmonary embolism and Sars-Cov-2 infection: A new indication for surgical pulmonary endarterectomy?

    Pilato, Emanuele / Manzo, Rachele / Comentale, Giuseppe

    Heart & lung : the journal of critical care

    2020  Volume 49, Issue 4, Page(s) 352

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Endarterectomy ; Humans ; Pandemics ; Pneumonia, Viral ; Prevalence ; Pulmonary Embolism ; SARS Virus ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 193129-5
    ISSN 1527-3288 ; 0147-9563
    ISSN (online) 1527-3288
    ISSN 0147-9563
    DOI 10.1016/j.hrtlng.2020.05.007
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    Zs.A 1035: Show issues Location:
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  9. Article ; Online: COVID-19 and ischemic heart disease emergencies: What cardiac surgery should expect?

    Pilato, Emanuele / Manzo, Rachele / Comentale, Giuseppe

    Journal of cardiac surgery

    2020  Volume 35, Issue 5, Page(s) 1161

    MeSH term(s) Acute Coronary Syndrome/complications ; Acute Coronary Syndrome/psychology ; Acute Coronary Syndrome/surgery ; Acute Coronary Syndrome/therapy ; COVID-19 ; Cardiac Care Facilities ; Cardiac Surgical Procedures ; Coronavirus Infections/psychology ; Coronavirus Infections/transmission ; Cross Infection/psychology ; Cross Infection/transmission ; Emergencies ; Fear ; Humans ; Infectious Disease Transmission, Professional-to-Patient/prevention & control ; Myocardial Ischemia/complications ; Myocardial Ischemia/psychology ; Myocardial Ischemia/surgery ; Myocardial Ischemia/therapy ; Pandemics ; Patient Acceptance of Health Care/psychology ; Pneumonia, Viral/psychology ; Pneumonia, Viral/transmission
    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country United States
    Document type Letter
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.14556
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    Zs.A 2221: Show issues Location:
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  10. Article ; Online: Sars-Cov-2 interference in HEME production: is it the time for an early predictive biomarker?

    Comentale, Giuseppe / Manzo, Rachele / Pilato, Emanuele

    Journal of molecular medicine (Berlin, Germany)

    2020  Volume 98, Issue 8, Page(s) 1053–1054

    MeSH term(s) Aminolevulinic Acid/metabolism ; Betacoronavirus/pathogenicity ; Biomarkers/analysis ; COVID-19 ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Heme/biosynthesis ; Host-Pathogen Interactions ; Humans ; Interleukin-6/blood ; Pandemics ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; Porphobilinogen/metabolism ; Porphobilinogen/urine ; SARS-CoV-2 ; Thrombosis/etiology ; Viral Proteins/metabolism
    Chemical Substances Biomarkers ; IL6 protein, human ; Interleukin-6 ; ORF8 protein, SARS-CoV-2 ; Viral Proteins ; Heme (42VZT0U6YR) ; Porphobilinogen (74KHC72QXK) ; Aminolevulinic Acid (88755TAZ87)
    Keywords covid19
    Language English
    Publishing date 2020-06-29
    Publishing country Germany
    Document type Letter
    ZDB-ID 1223802-8
    ISSN 1432-1440 ; 0946-2716
    ISSN (online) 1432-1440
    ISSN 0946-2716
    DOI 10.1007/s00109-020-01945-4
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