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  1. Article: With two episodes of right retromandibular angle subcutaneous emphysema during right upper molar crown preparation: A case report.

    Bai, Yun-Peng / Sha, Jing-Jing / Chai, Chang-Chang / Sun, Hai-Peng

    World journal of clinical cases

    2023  Volume 11, Issue 19, Page(s) 4698–4706

    Abstract: Background: Subcutaneous emphysema is a well-known complication of oral surgery, especially during mandibular wisdom tooth extraction. However, subcutaneous emphysema secondary to dental procedures such as crown preparation is rare. The main symptom of ... ...

    Abstract Background: Subcutaneous emphysema is a well-known complication of oral surgery, especially during mandibular wisdom tooth extraction. However, subcutaneous emphysema secondary to dental procedures such as crown preparation is rare. The main symptom of emphysema is swelling and crepitus on palpation. Uncontrolled emphysema may spread along the fascial planes and cause deep space infections or a pneumomediastinum.
    Case summary: In this paper, we report a 34-year-old female who underwent upper molar tooth preparation for crowns and subsequently developed extensive subcutaneous emphysema on the retromandibular angle on two different occasions. The treatment plan for this patient involved close observation of the airway, and administration of dexamethasone and antibiotics
    Conclusion: This case highlights the need for prompt diagnosis and management of subcutaneous emphysema because of the risk of much more serious complications. Awareness of relatively "benign" subcutaneous emphysema during any dental procedure is critical not only for inexperienced dentists, but also for those who work in rural and remote settings as members of surgical teams. In this study, we review the clinical presentation, mechanism, and differential diagnosis of subcutaneous emphysema.
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i19.4698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inflammatory and Nutritional Biomarkers in Patients With Esophageal Squamous Cell Carcinoma Undergoing Neoadjuvant Chemotherapy and Radiation Therapy.

    Huang, Chun Hou / Chang, Bee Song / Peng, Tai-Chu / Peng, Yun-Hsin

    Oncology nursing forum

    2024  Volume 51, Issue 2, Page(s) 177–192

    Abstract: Objectives: To investigate the relationship between pretreatment inflammatory and nutritional biomarkers in patients with esophageal squamous cell carcinoma (ESCC) undergoing neoadjuvant chemotherapy and radiation therapy (nCRT).: Sample & setting: ... ...

    Abstract Objectives: To investigate the relationship between pretreatment inflammatory and nutritional biomarkers in patients with esophageal squamous cell carcinoma (ESCC) undergoing neoadjuvant chemotherapy and radiation therapy (nCRT).
    Sample & setting: 213 patients with newly diagnosed stage II-III ESCC who received nCRT at an academic hospital in Taiwan.
    Methods & variables: Electronic health record data were used. Records on inflammatory and nutritional biomarkers and clinical outcomes were extracted. Logistic regression analysis was used to predict treatment-related adverse events, Cox regression was used for survival outcomes, and receiver operating characteristic curve analysis was used to determine optimal cutoff values.
    Results: There was a significant association between low prognostic nutritional index (PNI) and nCRT toxicities and survival. Advanced cancer stage, high platelet-to-lymphocyte ratio, and occurrence of pneumonia/infection were linked to survival outcomes.
    Implications for nursing: PNI shows promise in predicting prognosis, helps identify high-risk patients, and enables nurses to apply tailored interventions.
    MeSH term(s) Humans ; Esophageal Squamous Cell Carcinoma ; Neoadjuvant Therapy/adverse effects ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/radiotherapy ; Biomarkers ; Patients
    Chemical Substances Biomarkers
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604886-9
    ISSN 1538-0688 ; 0190-535X ; 1538-0688
    ISSN (online) 1538-0688 ; 0190-535X
    ISSN 1538-0688
    DOI 10.1188/24.ONF.177-192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chromosome-level genome assembly reveals potential epigenetic mechanisms of the thermal tolerance in the oriental fruit fly, Bactrocera dorsalis.

    Yang, Yang / Jiang, Hong-Bo / Liang, Chang-Hao / Ma, Yun-Peng / Dou, Wei / Wang, Jin-Jun

    International journal of biological macromolecules

    2022  

    Abstract: The oriental fruit fly, Bactrocera dorsalis (Hendel), has very strong ecological adaptability and phenotypic plasticity. Here, the genome of B. dorsalis was assembled into 549.45 Mb sequences with a contig N50 length of 12.81 Mb. Among, 95.67 % assembled ...

    Abstract The oriental fruit fly, Bactrocera dorsalis (Hendel), has very strong ecological adaptability and phenotypic plasticity. Here, the genome of B. dorsalis was assembled into 549.45 Mb sequences with a contig N50 length of 12.81 Mb. Among, 95.67 % assembled genome sequences were anchored on six chromosomes with an N50 length of 94.63 Mb. According to the basic characteristics of the sex chromosomes of Tephritidae, the X chromosome of B. dorsalis was identified. Significant gene expansions were detected in several important gene families related to adaptability. In particular, we annotated 50 histone modification enzymes (HMEs) in this genome. A comparative transcriptome analysis indicated that 12 HME genes were differentially expressed in two thermo-tolerant strains (heat and cold). Interestingly, four and seven of the 12 HME genes responded to heat shock or cold hardening, respectively. These evidences suggested that the histone modification as an epigenetic modification may be involved in the thermal tolerance of B. dorsalis, but with different regulation mechanisms in thermal acclimation and hardening. The high quality genome of B. dorsalis provides an invaluable resource for further functional genomic study. Moreover, comparative genomic analysis will shed insights on revealing the mechanisms of adaptive evolution in this fly.
    Language English
    Publishing date 2022-11-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.11.088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Association of frailty with in-hospital outcomes in elderly patients with heart failure.

    Kang, Yun-Peng / Chen, Li-Ying / Zhu, Jia-Jia / Liu, Wen-Xian / Ma, Chang-Sheng

    World journal of clinical cases

    2022  Volume 9, Issue 36, Page(s) 11208–11219

    Abstract: Background: Frailty is prevalent in elderly patients with cardiovascular diseases. However, the association between frailty and in-hospital outcomes for elderly patients with heart failure and reduced ejection (HFrEF) remains unknown.: Aim: To ... ...

    Abstract Background: Frailty is prevalent in elderly patients with cardiovascular diseases. However, the association between frailty and in-hospital outcomes for elderly patients with heart failure and reduced ejection (HFrEF) remains unknown.
    Aim: To evaluate the predictive efficacy of frailty, compared with pre-frailty, for adverse events in these patients.
    Methods: Elderly patients (≥ 60 years) with HFrEF were assessed. Frailty was evaluated with the Fried phenotype criteria, and physical performance was evaluated based on handgrip strength and the short physical performance battery (SPPB). The composite incidence of adverse events, including all-cause death, multiple organ failure, cardiac shock, and malignant arrhythmia, during hospitalization was recorded.
    Results: Overall, 252 elderly individuals with HFrEF [mean age: 69.4 ± 6.7 years, male: 169 (67.0%)] were included. One hundred and thirty-five (53.6%) patients were frail and 93 (36.9%) were pre-frail. Frail patients were older, more likely to be female, to have a lower blood pressure, and to present with left ventricular thrombosis (
    Conclusion: Frailty may be associated with poor in-hospital outcomes for elderly patients with HFrEF. The influence of frailty on long-term prognosis in these patients deserves further investigation.
    Language English
    Publishing date 2022-01-05
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v9.i36.11208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Characterization of gut microbial alterations in cynomolgus macaques during growth and maturation

    Yun-Peng Yang / Yong Lu / Pei-Jun Yu / Qi-Ming Liu / Chang-Shan Gao / Xiao-Tong Zhang / Qiang Sun

    Zoological Research, Vol 43, Iss 2, Pp 176-

    2022  Volume 179

    Keywords Zoology ; QL1-991
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Science Press, PR China
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Characterization of gut microbial alterations in cynomolgus macaques during growth and maturation.

    Yang, Yun-Peng / Lu, Yong / Yu, Pei-Jun / Liu, Qi-Ming / Gao, Chang-Shan / Zhang, Xiao-Tong / Sun, Qiang

    Zoological research

    2022  Volume 43, Issue 2, Page(s) 176–179

    MeSH term(s) Animals ; Gastrointestinal Microbiome ; Macaca fascicularis/growth & development ; Macaca fascicularis/microbiology
    Language English
    Publishing date 2022-01-27
    Publishing country China
    Document type Letter
    ISSN 2095-8137
    ISSN 2095-8137
    DOI 10.24272/j.issn.2095-8137.2021.304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Low-Temperature Methanolysis of Polycarbonate over Solid Base Sodium Aluminate.

    Krisbiantoro, Philip Anggo / Sato, Miyu / Lin, Tzu-Ming / Chang, Yu-Chia / Peng, Tzu-Yun / Wu, Yun-Chih / Liao, Weisheng / Kamiya, Yuichi / Otomo, Ryoichi / Wu, Kevin C-W

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 10, Page(s) 5338–5347

    Abstract: Herein, a low-cost and readily available sodium aluminate ( ... ...

    Abstract Herein, a low-cost and readily available sodium aluminate (NaAlO
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c03799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Four dodecanoic acid derivatives from the cold-seep-derived fungus

    Li, Chang-Peng / Song, Yin-Ping / Liang, Xiao-Rui / Ji, Nai-Yun

    Natural product research

    2023  , Page(s) 1–6

    Abstract: Two new compounds, cladospolides I ( ...

    Abstract Two new compounds, cladospolides I (
    Language English
    Publishing date 2023-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2214291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of Postoperative Prolonged sedation with Dexmedetomidine after successful reperfusion with Endovascular Thrombectomy on long-term prognosis in patients with acute ischemic stroke (PPDET): study protocol for a randomized controlled trial.

    Yang, Li-Na / Sun, Yi / Wang, Yu-Zhu / Wang, Jing / Qi, Yi-Sha / Mu, Shan-Shan / Liu, Yun-Peng / Zhang, Zi-Qing / Chen, Zi-Mo / Wang, Xiao-Jie / Xie, Wu-Xiang / Wei, Chang-Wei / Wang, Yang / Wu, An-Shi

    Trials

    2024  Volume 25, Issue 1, Page(s) 166

    Abstract: Background: Endovascular thrombectomy (EVT) is a standard treatment for acute ischemic stroke (AIS) with large vessel occlusion. Hypertension and increased blood pressure variability within the first 24 h after successful reperfusion are related to a ... ...

    Abstract Background: Endovascular thrombectomy (EVT) is a standard treatment for acute ischemic stroke (AIS) with large vessel occlusion. Hypertension and increased blood pressure variability within the first 24 h after successful reperfusion are related to a higher risk of symptomatic intracerebral hemorrhage and higher mortality. AIS patients might suffer from ischemia-reperfusion injury following reperfusion, especially within 24 h. Dexmedetomidine (DEX), a sedative commonly used in EVT, can stabilize hemodynamics by inhibiting the sympathetic nervous system and alleviate ischemia-reperfusion injury through anti-inflammatory and antioxidative properties. Postoperative prolonged sedation for 24 h with DEX might be a potential pharmacological approach to improve long-term prognosis after EVT.
    Methods: This single-center, open-label, prospective, randomized controlled trial will include 368 patients. The ethics committee has approved the protocol. After successful reperfusion (modified thrombolysis in cerebral infarction scores 2b-3, indicating reperfusion of at least 50% of the affected vascular territory), participants are randomly assigned to the intervention or control group. In the intervention group, participants will receive 0.1~1.0 μg/kg/h DEX for 24 h. In the control group, participants will receive an equal dose of saline for 24 h. The primary outcome is the functional outcome at 90 days, measured with the categorical scale of the modified Rankin Scale, ranging from 0 (no symptoms) to 6 (death). The secondary outcome includes (1) the changes in stroke severity between admission and 24 h and 7 days after EVT, measured by the National Institute of Health Stroke Scale (ranging from 0 to 42, with higher scores indicating greater severity); (2) the changes in ischemic penumbra volume/infarct volume between admission and 7 days after EVT, measured by neuroimaging scan; (3) the length of ICU/hospital stay; and (4) adverse events and the all-cause mortality rate at 90 days.
    Discussion: This randomized clinical trial is expected to verify the hypothesis that postoperative prolonged sedation with DEX after successful reperfusion may promote the long-term prognosis of patients with AIS and may reduce the related socio-economic burden.
    Trial registration: ClinicalTrials.gov NCT04916197. Prospectively registered on 7 June 2021.
    MeSH term(s) Humans ; Ischemic Stroke/diagnosis ; Ischemic Stroke/surgery ; Dexmedetomidine/adverse effects ; Prospective Studies ; Reperfusion ; Thrombectomy/adverse effects ; Stroke/diagnosis ; Stroke/therapy ; Reperfusion Injury/etiology ; Reperfusion Injury/prevention & control ; Prognosis ; Randomized Controlled Trials as Topic
    Chemical Substances Dexmedetomidine (67VB76HONO)
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-024-08015-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Transcription factors AcERF74/75 respond to waterlogging stress and trigger alcoholic fermentation-related genes in kiwifruit

    Liu, Jiao / Chen, Yue / Wang, Wen-qiu / Liu, Ji-hong / Zhu, Chang-qing / Zhong, Yun-peng / Zhang, Hui-qin / Liu, Xiao-fen / Yin, Xue-ren

    Plant science. 2022 Jan., v. 314

    2022  

    Abstract: Kiwifruit plants have a fleshy, shallow root system which is sensitive to waterlogging stress, which results in a decrease in crop yield or even plants death. Although the waterlogging stress responses in kiwifruit have attracted much attention, the ... ...

    Abstract Kiwifruit plants have a fleshy, shallow root system which is sensitive to waterlogging stress, which results in a decrease in crop yield or even plants death. Although the waterlogging stress responses in kiwifruit have attracted much attention, the underlying molecular mechanism remains unclear. In this study, waterlogging led to drastic inhibition of root growth of ‘Donghong’ kiwifruit (Actinidia chinensis) plants grown in vitro, which was accompanied by significant elevation of endogenous acetaldehyde and ethanol contents. RNA-seq of roots of plants waterlogged for 0, 1 and 2 days revealed that a total of 149 genes were up- or down-regulated, including seven biosynthetic genes related to the glycolysis/gluconeogenesis pathway and 10 transcription factors. Analyses with real-time PCR, dual-luciferase assays and EMSA demonstrated that AcERF74 and AcERF75, two members of the ERF-VII subfamily, directly upregulated AcADH1 (alcohol dehydrogenase). Moreover, the overexpression of AcERF74/75 in transgenic calli resulted in dramatic increase of endogenous ethanol contents through the triggering of AcADH1 and AcADH2 expression. Although the AcPDC2 (pyruvate decarboxylase) expression was also enhanced in transgenic lines, the endogenous acetaldehyde contents showed no significant changes. These results illustrated that AcERF74/75 are two transcriptional activators on alcoholic fermentation related genes and are responsive to waterlogging stress in kiwifruit.
    Keywords Actinidia chinensis ; acetaldehyde ; alcohol dehydrogenase ; alcoholic fermentation ; biosynthesis ; callus ; crop yield ; death ; ethanol ; genetically modified organisms ; gluconeogenesis ; glycolysis ; kiwifruit ; pyruvate decarboxylase ; quantitative polymerase chain reaction ; root growth ; root systems ; sequence analysis ; transcription (genetics)
    Language English
    Dates of publication 2022-01
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 742010-9
    ISSN 1873-2259 ; 0168-9452
    ISSN (online) 1873-2259
    ISSN 0168-9452
    DOI 10.1016/j.plantsci.2021.111115
    Database NAL-Catalogue (AGRICOLA)

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