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  1. Article ; Online: Current Topics in Dentistry.

    Lauritano, Dorina

    Current topics in medicinal chemistry

    2020  Volume 19, Issue 31, Page(s) 2815

    MeSH term(s) Ambulatory Care Facilities/organization & administration ; Dental Health Services/organization & administration ; Dentistry ; Humans
    Language English
    Publishing date 2020-01-10
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/156802661931200103180728
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5572: Show issues Location:
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  2. Article ; Online: Perspective in Medicinal Chemistry.

    Lauritano, Dorina

    Current topics in medicinal chemistry

    2019  Volume 18, Issue 23, Page(s) 2000–2001

    MeSH term(s) Biocompatible Materials ; Chemistry, Pharmaceutical/trends ; Dentistry ; Pharmaceutical Preparations ; Publishing
    Chemical Substances Biocompatible Materials ; Pharmaceutical Preparations
    Language English
    Publishing date 2019-01-18
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/156802661823190110112258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Transcriptome Mining to Identify Genes of Interest: From Local Databases to Phylogenetic Inference.

    De Luca, Daniele / Lauritano, Chiara

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2498, Page(s) 43–51

    Abstract: The advancement in next-generation sequencing technologies and the dropping of sequencing costs have seen an increase in the amount of transcriptome data generated each year. These data are of big potential for identifying genes and molecular pathways of ...

    Abstract The advancement in next-generation sequencing technologies and the dropping of sequencing costs have seen an increase in the amount of transcriptome data generated each year. These data are of big potential for identifying genes and molecular pathways of interest across a plethora of organisms. However, navigating these resources requires some bioinformatics and evolutionary skills. Here, we describe a protocol of transcriptome data mining for genes of interest, from the creation of a protein database to the inference of phylogenetic trees, which was used for marine protists, but can be used as general pipeline across different taxa.
    MeSH term(s) Computational Biology/methods ; Data Mining/methods ; High-Throughput Nucleotide Sequencing ; Phylogeny ; Transcriptome
    Language English
    Publishing date 2022-06-21
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2313-8_3
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  4. Article: A new chemical device for the treatment of chronic periodontitis: a case control study.

    Baldoni, M / Lauritano, D

    Journal of biological regulators and homeostatic agents

    2021  Volume 33, Issue 6 Suppl. 1, Page(s) 99–106

    Abstract: The objective of this study was to compare the efficacy of supportive periodontal therapy (i.e. scaling and root planning, SRP) alone, versus a chemical device silica dioxide (SiO2) colloidal solutions (SDCS) used in association with SRP in the treatment ...

    Abstract The objective of this study was to compare the efficacy of supportive periodontal therapy (i.e. scaling and root planning, SRP) alone, versus a chemical device silica dioxide (SiO2) colloidal solutions (SDCS) used in association with SRP in the treatment of chronic periodontitis in adult patients. A total of 20 patients with a diagnosis of chronic periodontitis (40 localized chronic periodontitis sites) in the age group of 35 to 55 were selected. None of these patients have previously received any surgical or non-surgical periodontal therapy and demonstrated radiographic evidence of moderate bone loss. Two non-adjacent sites in separate quadrants were selected in each patient to monitor treatment efficacy (split mouth design). Clinical pocket depth (PD) and microbial analysis (MA) were analyzed at baseline day 15. SPSS program and paired simple statistic T-test were used to detect significant differences. Total bacteria loading, Tannerella forsitia and Treponema denticola loading were statistically reduced when SiO2 is locally delivered. SDCS gel is an adjuvant therapy which should be added to SRP in the management of moderate to severe chronic periodontitis.
    MeSH term(s) Adult ; Case-Control Studies ; Chronic Periodontitis/therapy ; Dental Scaling ; Follow-Up Studies ; Humans ; Middle Aged ; Periodontal Pocket ; Root Planing ; Silicon Dioxide ; Treatment Outcome
    Chemical Substances Silicon Dioxide (7631-86-9)
    Language English
    Publishing date 2021-08-06
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 639196-5
    ISSN 1724-6083 ; 0393-974X
    ISSN (online) 1724-6083
    ISSN 0393-974X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article: One-piece implants: an alternative rehabilitation of edentuluos jaws.

    Baldoni, M / Lauritano, D

    Journal of biological regulators and homeostatic agents

    2020  Volume 33, Issue 6 Suppl. 1, Page(s) 33–40. DENTAL SUPPLEMENT

    Abstract: The popularity of one-piece implants has increased considerably between patients and dentists. The advantages of one-piece immediate loading for rehabilitation of edentulous mandibles are to reduce the number of interventions and timing of prosthetic. ... ...

    Abstract The popularity of one-piece implants has increased considerably between patients and dentists. The advantages of one-piece immediate loading for rehabilitation of edentulous mandibles are to reduce the number of interventions and timing of prosthetic. These parameters can be better controlled with a one-piece implant. Twenty-one patients with one-piece implants inserted in totally edentulous mandibles were considered for this retrospective study. Inclusion criteria were: Good oral hygiene, absence of lesions of the oral mucosa, no smoking or smoking less than 20 cigarettes a day, drinking less than 2 glasses of wine a day, good general health no pregnancy. Twenty-one (12 female 9 males) patients were enrolled in this retrospective study. The mean follow-up was 1 year. A total 84 one-piece implants (Biohorizon, Italy) were inserted in edentulous mandible. Implants diameter was 3,0 mm in all fixtures. Implant's length was equal and longer than 12 mm in 44 and 40 fixtures respectively. 48 were inserted in females 36 in males (range 33-67; mean age 58,3). One-piece immediate loading implants has non-difference in survival rate respect to two-piece implant and delayed loading for rehabilitation of totally edentulous mandibles. In conclusion one-piece immediate loading implant is a reliable device for mandible rehabilitation.
    Language English
    Publishing date 2020-01-16
    Publishing country Italy
    Document type Observational Study
    ZDB-ID 639196-5
    ISSN 1724-6083 ; 0393-974X
    ISSN (online) 1724-6083
    ISSN 0393-974X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Características produtivas de novilhas submetidas à restrição alimentar e dieta suplementada com vitaminas D e E

    Marina Parrili / Sueli Akemi Matsuhara / Mário De Beni Arrigoni / Cyntia Ludovico Martins / Danilo Domingues Millen / Rodrigo Dias Lauritano Pacheco / Luis Marcelo Nave Sarti / Samira Rodrigues Baldin / Fernando Salvador Parra

    Pesquisa Agropecuária Brasileira, Vol 46, Iss 8, Pp 920-

    2011  Volume 927

    Abstract: ... com vitaminas D e E sobre o desempenho e características de carcaça de novilhas Canchim. Vinte e quatro fêmeas ... em quantidade restrita e não restrita, com e sem suplementação de vitaminas D e E. Utilizou-se o delineamento ... nem as características de carcaça das novilhas Canchim, e a suplementação com vitaminas D e E não melhora a qualidade ...

    Abstract O objetivo deste trabalho foi avaliar os efeitos da restrição alimentar e de dieta de suplementação com vitaminas D e E sobre o desempenho e características de carcaça de novilhas Canchim. Vinte e quatro fêmeas, com peso vivo inicial médio de 251,95±18,49 kg, foram distribuídas em quatro tratamentos: alimentação em quantidade restrita e não restrita, com e sem suplementação de vitaminas D e E. Utilizou-se o delineamento inteiramente casualizado, em arranjo fatorial 2x2, com seis repetições. Os animais com alimentação restrita receberam, por 48 dias, 70% da dieta fornecida ao grupo de alimentação não restrita. Após o período de restrição (peso médio de 300,10 kg), eles voltaram a receber ração à vontade por mais 77 dias, até atingirem peso de abate de 380 kg. As avaliações foram feitas ao final dos períodos de restrição e de realimentação. Não foi observado efeito da restrição alimentar sobre o desempenho animal. Novilhas que não receberam suplementação vitamínica apresentaram maiores índices de fragmentação miofibrilar, luminosidade e mastigabilidade, e menor força de cisalhamento. A restrição alimentar não afeta o desempenho nem as características de carcaça das novilhas Canchim, e a suplementação com vitaminas D e E não melhora a qualidade da carne.
    Keywords Bos taurus ; Canchim ; confinamento ; crescimento compensatório ; desempenho ; terminação ; Agriculture (General) ; S1-972
    Language English
    Publishing date 2011-08-01T00:00:00Z
    Publisher Embrapa Informação Tecnológica
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Recent Discoveries on Marine Organism Immunomodulatory Activities.

    Montuori, Eleonora / de Pascale, Donatella / Lauritano, Chiara

    Marine drugs

    2022  Volume 20, Issue 7

    Abstract: Marine organisms have been shown to be a valuable source for biologically active compounds for the prevention and treatment of cancer, inflammation, immune system diseases, and other pathologies. The advantage of studying organisms collected in the ... ...

    Abstract Marine organisms have been shown to be a valuable source for biologically active compounds for the prevention and treatment of cancer, inflammation, immune system diseases, and other pathologies. The advantage of studying organisms collected in the marine environment lies in their great biodiversity and in the variety of chemical structures of marine natural products. Various studies have focused on marine organism compounds with potential pharmaceutical applications, for instance, as immunomodulators, to treat cancer and immune-mediated diseases. Modulation of the immune system is defined as any change in the immune response that can result in the induction, expression, amplification, or inhibition of any phase of the immune response. Studies very often focus on the effects of marine-derived compounds on macrophages, as well as lymphocytes, by analyzing the release of mediators (cytokines) by using the immunological assay enzyme-linked immunosorbent assay (ELISA), Western blot, immunofluorescence, and real-time PCR. The main sources are fungi, bacteria, microalgae, macroalgae, sponges, mollusks, corals, and fishes. This review is focused on the marine-derived molecules discovered in the last three years as potential immunomodulatory drugs.
    MeSH term(s) Animals ; Aquatic Organisms/chemistry ; Bacteria ; Biological Products/pharmacology ; Biological Products/therapeutic use ; Fungi/chemistry ; Immunity ; Neoplasms/drug therapy
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-06-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md20070422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Review of Toxins from Cnidaria.

    D'Ambra, Isabella / Lauritano, Chiara

    Marine drugs

    2020  Volume 18, Issue 10

    Abstract: Cnidarians have been known since ancient times for the painful stings they induce to humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in death of human beings. The noxious effects of cnidarian venoms have ... ...

    Abstract Cnidarians have been known since ancient times for the painful stings they induce to humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in death of human beings. The noxious effects of cnidarian venoms have stimulated the definition of their composition and their activity. Despite this interest, only a limited number of compounds extracted from cnidarian venoms have been identified and defined in detail. Venoms extracted from Anthozoa are likely the most studied, while venoms from Cubozoa attract research interests due to their lethal effects on humans. The investigation of cnidarian venoms has benefited in very recent times by the application of omics approaches. In this review, we propose an updated synopsis of the toxins identified in the venoms of the main classes of Cnidaria (Hydrozoa, Scyphozoa, Cubozoa, Staurozoa and Anthozoa). We have attempted to consider most of the available information, including a summary of the most recent results from omics and biotechnological studies, with the aim to define the state of the art in the field and provide a background for future research.
    MeSH term(s) Animals ; Cnidaria/physiology ; Cnidarian Venoms/chemistry ; Cnidarian Venoms/metabolism ; Genomics ; Metabolomics
    Chemical Substances Cnidarian Venoms
    Language English
    Publishing date 2020-10-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md18100507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: In Silico Identification of Type III PKS Chalcone and Stilbene Synthase Homologs in Marine Photosynthetic Organisms.

    De Luca, Daniele / Lauritano, Chiara

    Biology

    2020  Volume 9, Issue 5

    Abstract: Marine microalgae are photosynthetic microorganisms at the base of the marine food webs. They are characterized by huge taxonomic and metabolic diversity and several species have been shown to have bioactivities useful for the treatment of human ... ...

    Abstract Marine microalgae are photosynthetic microorganisms at the base of the marine food webs. They are characterized by huge taxonomic and metabolic diversity and several species have been shown to have bioactivities useful for the treatment of human pathologies. However, the compounds and the metabolic pathways responsible for bioactive compound synthesis are often still unknown. In this study, we aimed at analysing the microalgal transcriptomes available in the Marine Microbial Eukaryotic Transcriptome Sequencing Project (MMETSP) database for an
    Language English
    Publishing date 2020-05-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology9050110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Inflammatory bowel syndrome and oral health: a two-way relationship.

    Baldoni, M / Lauritano, D

    Journal of biological regulators and homeostatic agents

    2019  Volume 33, Issue 6 Suppl. 1, Page(s) 29–30. DENTAL SUPPLEMENT

    Language English
    Publishing date 2019-12-29
    Publishing country Italy
    Document type Letter
    ZDB-ID 639196-5
    ISSN 1724-6083 ; 0393-974X
    ISSN (online) 1724-6083
    ISSN 0393-974X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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