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  1. Article ; Online: A gold mine of information from a deep dive into the liver transcriptome.

    Mehal, Wajahat Z

    Journal of hepatology

    2024  Volume 80, Issue 4, Page(s) 540–542

    MeSH term(s) Liver ; Transcriptome
    Language English
    Publishing date 2024-01-18
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2024.01.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Letter to the Editor: Concerns regarding the use of fatty liver index in studies of lean NAFLD.

    Zahrawi, Frhaan M / Mehal, Wajahat Z

    Hepatology (Baltimore, Md.)

    2024  Volume 79, Issue 5, Page(s) E129

    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease ; Liver Function Tests ; Body Mass Index
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1097/HEP.0000000000000754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A disease-promoting role of the intestinal mycobiome in non-alcoholic fatty liver disease.

    Mehal, Wajahat Z / Schwabe, Robert F

    Journal of hepatology

    2022  Volume 76, Issue 4, Page(s) 765–767

    MeSH term(s) Gastrointestinal Microbiome ; Humans ; Intestines ; Mycobiome ; Non-alcoholic Fatty Liver Disease
    Language English
    Publishing date 2022-01-21
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.12.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acetyl-Coenzyme A carboxylase inhibition Delivers, as Anticipated, for Patients With Nonalcoholic Steatohepatitis.

    Mehal, Wajahat Z

    Gastroenterology

    2018  Volume 155, Issue 5, Page(s) 1304–1306

    MeSH term(s) Acetyl-CoA Carboxylase ; Coenzymes ; Humans ; Kinetics ; Non-alcoholic Fatty Liver Disease
    Chemical Substances Coenzymes ; Acetyl-CoA Carboxylase (EC 6.4.1.2)
    Language English
    Publishing date 2018-10-08
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2018.10.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review.

    Zahrawi, Frhaan / Fathma, Sawsan / Mehal, Wajahat Z / Banini, Bubu A

    Annals of gastroenterology and digestive disorders

    2023  Volume 6, Issue 1, Page(s) 17–25

    Abstract: Post liver transplant obesity is associated with the development of metabolic disorders such as diabetes mellitus and nonalcoholic fatty liver disease and is a strong predictor of post-transplant mortality. Anti-obesity pharmacotherapy could serve as an ... ...

    Abstract Post liver transplant obesity is associated with the development of metabolic disorders such as diabetes mellitus and nonalcoholic fatty liver disease and is a strong predictor of post-transplant mortality. Anti-obesity pharmacotherapy could serve as an effective adjunct to lifestyle modification in the post-transplant setting. Currently, utilization of anti-obesity medication in post liver transplant patients is limited by scarce data on their efficacy and safety in the post-transplant setting. Newer classes of anti-obesity medications, including the glucagon-like peptide 1 agonists (GLP-1) do not only help with weight loss but are effective anti-diabetic agents and are in further development for their potential hepatoprotective and renoprotective effects and reduction in cardiovascular risk. The objective of this manuscript was to critically review the efficacy and safety of anti-obesity pharmacotherapy in post-liver transplant patients.
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: We are not in Kansas anymore: The unfamiliar landscape of NASH.

    Mehal, Wajahat Z

    Hepatology (Baltimore, Md.)

    2016  Volume 63, Issue 3, Page(s) 682–684

    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/therapy ; Obesity/complications ; Weight Loss
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.28348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Intestinal Microbiome, Plasma Metabolome, and Liver Transcriptome: A Conspiracy Driving Hepatic Steatosis.

    Mehal, Wajahat Z / Loomba, Rohit

    Hepatology (Baltimore, Md.)

    2019  Volume 70, Issue 2, Page(s) 741–744

    MeSH term(s) Fatty Liver/etiology ; Fatty Liver/genetics ; Fatty Liver/metabolism ; Gastrointestinal Microbiome/physiology ; Humans ; Liver ; Metabolome ; Transcriptome
    Language English
    Publishing date 2019-04-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.30577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders.

    Jamshed, Fatima / Dashti, Farzaneh / Ouyang, Xinshou / Mehal, Wajahat Z / Banini, Bubu A

    World journal of gastroenterology

    2023  Volume 29, Issue 12, Page(s) 1824–1837

    Abstract: Repurposing of the widely available and relatively cheap generic cardiac gly-coside digoxin for non-cardiac indications could have a wide-ranging impact on the global burden of several diseases. Over the past several years, there have been significant ... ...

    Abstract Repurposing of the widely available and relatively cheap generic cardiac gly-coside digoxin for non-cardiac indications could have a wide-ranging impact on the global burden of several diseases. Over the past several years, there have been significant advances in the study of digoxin pharmacology and its potential non-cardiac clinical applications, including anti-inflammatory, antineoplastic, metabolic, and antimicrobial use. Digoxin holds promise in the treatment of gastrointestinal disease, including nonalcoholic steatohepatitis and alcohol-associated steatohepatitis as well as in obesity, cancer, and treatment of viral infections, among other conditions. In this review, we provide a summary of the clinical uses of digoxin to date and discuss recent research on its emerging applications.
    MeSH term(s) Humans ; Digoxin/therapeutic use ; Digoxin/pharmacology ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/metabolism ; Fatty Liver, Alcoholic/drug therapy ; Obesity/drug therapy ; Anti-Inflammatory Agents/therapeutic use
    Chemical Substances Digoxin (73K4184T59) ; Anti-Inflammatory Agents
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v29.i12.1824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Who is the scientist in bio-medical research, the author or the reviewer?

    Mehal, Wajahat Z

    Frontiers in pharmacology

    2014  Volume 5, Page(s) 50

    Language English
    Publishing date 2014-03-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2014.00050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: CELLS ON FIRE.

    Mehal, Wajahat Z

    Scientific American

    2015  Volume 312, Issue 6, Page(s) 44–49

    MeSH term(s) Alzheimer Disease/etiology ; Alzheimer Disease/physiopathology ; Atherosclerosis/etiology ; Atherosclerosis/physiopathology ; Cell Physiological Phenomena ; Cytokines/physiology ; Eating ; Fatty Liver/etiology ; Fatty Liver/physiopathology ; Food ; Humans ; Immune System/physiopathology ; Inflammasomes/physiology ; Inflammation/physiopathology ; Overnutrition
    Chemical Substances Cytokines ; Inflammasomes
    Language English
    Publishing date 2015-08-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 246-x
    ISSN 1946-7087 ; 0036-8733
    ISSN (online) 1946-7087
    ISSN 0036-8733
    DOI 10.1038/scientificamerican0615-44
    Database MEDical Literature Analysis and Retrieval System OnLINE

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