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  1. Article: Examining the Geospatial Distribution of Health and Support Services for Transgender, Gender Nonbinary, and Other Gender Diverse People in New York City.

    Callander, Denton / Kim, Byoungjun / Domingo, Micah / Tabb, Loni Philip / Radix, Asa / Timmins, Liadh / Baradaran, Amir / Clark, Michael B / Duncan, Dustin T

    Transgender health

    2022  Volume 7, Issue 4, Page(s) 369–374

    Abstract: A geospatial analysis of services that support transgender and gender diverse ("trans") people in New York City (NYC) was conducted to investigate associations with neighborhood-level sociodemographic characteristics. In June 2019, there were 5.3 ... ...

    Abstract A geospatial analysis of services that support transgender and gender diverse ("trans") people in New York City (NYC) was conducted to investigate associations with neighborhood-level sociodemographic characteristics. In June 2019, there were 5.3 services for every 100,000 of the general NYC population; controlling for other covariates, they were more commonly located in neighborhoods with larger populations of non-Hispanic Black (rate ratio [RR]=1.02, 95% confidence interval [CI]: 1.00-1.04), Hispanic/Latino (RR=1.03, 95% CI: 1.00-1.06), and gay/lesbian people (RR=1.53, 95% CI: 1.03-2.34). These findings suggest that the distribution of trans-focused services in NYC is proximal to communities that are most in need, but research should examine proximity to trans people specifically and distribution in nonurban areas.
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Journal Article
    ISSN 2688-4887
    ISSN 2688-4887
    DOI 10.1089/trgh.2020.0144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Morning perception of sleep, stress, and mood, and its relationship with overnight physiological sleep: findings from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study.

    Albinni, Benedetta / Baker, Fiona C / Javitz, Harold / Hasler, Brant P / Franzen, Peter L / Clark, Duncan B / de Zambotti, Massimiliano

    Journal of sleep research

    2023  Volume 32, Issue 5, Page(s) e13886

    Abstract: This cross-sectional study investigated objective-subjective sleep discrepancies and the physiological basis for morning perceptions of sleep, mood, and readiness, in adolescents. Data collected during a single in-laboratory polysomnographic assessment ... ...

    Abstract This cross-sectional study investigated objective-subjective sleep discrepancies and the physiological basis for morning perceptions of sleep, mood, and readiness, in adolescents. Data collected during a single in-laboratory polysomnographic assessment from 137 healthy adolescents (61 girls; age range: 12-21 years) in the United States National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study were analysed. Upon awakening, participants completed questionnaires assessing sleep quality, mood, and readiness. We evaluated the relationship between overnight polysomnographic, electroencephalographic, sleep autonomic nervous system functioning measures, and next morning self-reported indices. Results showed that older adolescents reported more awakenings, yet they perceived their sleep to be deeper and less restless than younger adolescents. Prediction models including sleep physiology measures (polysomnographic, electroencephalographic, and sleep autonomic nervous system) explained between 3% and 29% of morning sleep perception, mood, and readiness indices. The subjective experience of sleep is a complex phenomenon with multiple components. Distinct physiological sleep processes contribute to the morning perception of sleep and related measures of mood and readiness. More than 70% of the variance (based on a single observation per person) in the perception of sleep, mood, and morning readiness is not explained by overnight sleep-related physiological measures, suggesting that other factors are important for the subjective sleep experience.
    MeSH term(s) Female ; Humans ; Adolescent ; Child ; Young Adult ; Adult ; Polysomnography/methods ; Cross-Sectional Studies ; Sleep/physiology ; Electroencephalography ; Perception
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/jsr.13886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Differential Item Functioning in Reports of Delinquent Behavior Between Black and White Youth: Evidence of Measurement Bias in Self-Reports of Arrest in the Adolescent Brain Cognitive Development Study.

    Brislin, Sarah J / Clark, D Angus / Clark, Duncan B / Durbin, C Emily / Parr, Ashley C / Ahonen, Lia / Anderson-Carpenter, Kaston D / Heitzeg, Mary M / Luna, Beatriz / Sripada, Chandra / Zucker, Robert A / Hicks, Brian M

    Assessment

    2023  Volume 31, Issue 2, Page(s) 444–459

    Abstract: Youth self-reports are a mainstay of delinquency assessment; however, making valid inferences about delinquency using these assessments requires equivalent measurement across groups of theoretical interest. We examined whether a brief 10-item delinquency ...

    Abstract Youth self-reports are a mainstay of delinquency assessment; however, making valid inferences about delinquency using these assessments requires equivalent measurement across groups of theoretical interest. We examined whether a brief 10-item delinquency measure exhibited measurement invariance across non-Hispanic White (
    MeSH term(s) Child ; Humans ; Brain ; Cognition ; Self Report ; Black or African American ; White ; Bias ; Juvenile Delinquency
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1362144-0
    ISSN 1552-3489 ; 1073-1911
    ISSN (online) 1552-3489
    ISSN 1073-1911
    DOI 10.1177/10731911231164627
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Racial Bias in School Discipline and Police Contact: Evidence From the Adolescent Brain Cognitive Development Social Development (ABCD-SD) Study.

    Brislin, Sarah J / Choi, Maia / Perkins, Emily R / Ahonen, Lia / McCoy, Henrika / Boxer, Paul / Clark, Duncan B / Jackson, Dylan B / Hicks, Brian M

    Journal of the American Academy of Child and Adolescent Psychiatry

    2024  

    Abstract: Objective: Black youth are disproportionately exposed to school exclusionary discipline. We examined the impact of race on age at the onset of school disciplinary actions and police contact, and the rate of receiving increasingly severe disciplinary ... ...

    Abstract Objective: Black youth are disproportionately exposed to school exclusionary discipline. We examined the impact of race on age at the onset of school disciplinary actions and police contact, and the rate of receiving increasingly severe disciplinary actions.
    Method: Youth (N = 2,156) and their caregivers participating in the Adolescent Brain Cognitive Development Social Development (ABCD-SD) study reported on the occurrence and timing of disciplinary events and youths' demographics, delinquency, and neighborhood conditions. Experiences of exclusionary discipline were analyzed using logistic regression and Cox proportional hazards models.
    Results: Black youth reported significantly higher rates of almost all disciplinary events compared to White youth. In logistic regression and Cox models, Black youth experienced higher risk for exclusionary discipline and police contact (odds ratios from 2.47 [detention] to 5.16 [sent home]; hazard ratios from 1.36 [detention] to 4.71 [expelled]), even after adjusting for sex, delinquency, neighborhood conditions, and the interaction between race and sex. Black youth who received detention and suspension were at higher risk for additional, more severe school discipline than were White youth.
    Conclusion: Consistent with a racial bias in exclusionary discipline practices and policing, Black youth, particularly Black male youth, were at a higher risk for experiencing almost all disciplinary outcomes and at younger ages than White youth, after controlling for delinquency, sex, and neighborhood factors. Compared to White students, school detention and suspension status predicted an accelerated cascade of school discipline outcomes for Black students, suggesting racial disparities in how the severity of school discipline escalates over time.
    Diversity & inclusion statement: We worked to ensure that the study questionnaires were prepared in an inclusive way. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list.
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2024.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Preliminary Evidence That Circadian Alignment Predicts Neural Response to Monetary Reward in Late Adolescent Drinkers.

    Hasler, Brant P / Graves, Jessica L / Soehner, Adriane M / Wallace, Meredith L / Clark, Duncan B

    Frontiers in neuroscience

    2022  Volume 16, Page(s) 803349

    Abstract: Background: Robust evidence links sleep and circadian rhythm disturbances to alcohol use and alcohol-related problems, with a growing literature implicating reward-related mechanisms. However, the extant literature has been limited by cross-sectional ... ...

    Abstract Background: Robust evidence links sleep and circadian rhythm disturbances to alcohol use and alcohol-related problems, with a growing literature implicating reward-related mechanisms. However, the extant literature has been limited by cross-sectional designs, self-report or behavioral proxies for circadian timing, and samples without substantive alcohol use. Here, we employed objective measures of sleep and circadian rhythms, and an intensive prospective design, to assess whether circadian alignment predicts the neural response to reward in a sample of late adolescents reporting regular alcohol use.
    Methods: Participants included 31 late adolescents (18-22 y/o; 19 female participants) reporting weekly alcohol use. Participants completed a 14-day protocol including pre- and post-weekend (Thursday and Sunday) circadian phase assessments
    Results: In primary analyses, shorter DLMO-midsleep intervals (i.e., greater misalignment) on Thursday predicted lower striatal and mPFC responses to anticipated reward, but not reward outcome, on Friday. Lower neural (striatum and mPFC) responses to anticipated reward on Friday correlated with more binge-drinking episodes at baseline, but were not associated with alcohol use in the post-scan weekend. In secondary analyses, greater social jet lag (particularly larger weekend delays in midsleep or DLMO) was associated with lower neural responses to reward anticipation on Monday.
    Conclusion: Findings provide preliminary evidence of proximal associations between objectively determined circadian alignment and the neural response to anticipated monetary reward, which is linked in turn to patterns of problematic drinking. Replication in a larger sample and experimental designs will be important next steps to determining the extent to which circadian misalignment influences risk for alcohol involvement
    Language English
    Publishing date 2022-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2022.803349
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  6. Article ; Online: Pre-pandemic circadian phase predicts pandemic alcohol use among adolescents.

    Hasler, Brant P / Wallace, Meredith L / Graves, Jessica L / Witt, Rachel / Guo, Kathryn / Buysse, Daniel J / Siegle, Greg J / Clark, Duncan B

    Journal of sleep research

    2023  Volume 33, Issue 1, Page(s) e13905

    Abstract: Later circadian timing during adolescence is linked to worse sleep, more severe depression and greater alcohol involvement, perhaps due to circadian misalignment imposed by early school schedules. School schedules shifted later during the COVID-19 ... ...

    Abstract Later circadian timing during adolescence is linked to worse sleep, more severe depression and greater alcohol involvement, perhaps due to circadian misalignment imposed by early school schedules. School schedules shifted later during the COVID-19 pandemic, ostensibly reducing circadian misalignment and potentially mitigating problems with depression and alcohol. We used the pandemic as a natural experiment to test whether adolescent drinkers with later circadian timing showed improvements in sleep, depression and alcohol involvement. Participants were 42 adolescents reporting alcohol use. We assessed circadian phase via dim light melatonin onset prior to the pandemic, then conducted remote assessments of sleep, depressive symptoms and alcohol use during the pandemic. Mixed-effects models were used to test for pandemic effects, covarying for age, sex, time since baseline evaluation, and current school/work status. Adolescents with later circadian timing reported less sleep than other teens on school nights, both before and during the pandemic. Although school night sleep increased during the pandemic (F = 28.36, p < 0.001), those increases were not greater for individuals with later circadian timing. Individuals with later circadian timing reported larger increases in alcohol use than other teens during the pandemic (X
    MeSH term(s) Humans ; Adolescent ; Circadian Rhythm ; Pandemics ; Sleep ; Alcohol Drinking/epidemiology ; Disorders of Excessive Somnolence ; Ethanol ; Melatonin
    Chemical Substances Ethanol (3K9958V90M) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2023-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/jsr.13905
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  7. Article ; Online: Associations between frontal lobe structure, parent-reported obstructive sleep disordered breathing and childhood behavior in the ABCD dataset

    Amal Isaiah / Thomas Ernst / Christine C. Cloak / Duncan B. Clark / Linda Chang

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 10

    Abstract: Parents often report behavioral problems in children with symptoms of sleep disordered breathing (oSDB), such as snoring. Here, the authors show that lower brain volumes within the frontal lobe are associated with parent-reported problem behaviors in ... ...

    Abstract Parents often report behavioral problems in children with symptoms of sleep disordered breathing (oSDB), such as snoring. Here, the authors show that lower brain volumes within the frontal lobe are associated with parent-reported problem behaviors in children with parent-reported symptoms of oSDB.
    Keywords Science ; Q
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Profiling the Effects of Systemic Antibiotics for Acne, Including the Narrow-Spectrum Antibiotic Sarecycline, on the Human Gut Microbiota.

    Moura, Ines B / Grada, Ayman / Spittal, William / Clark, Emma / Ewin, Duncan / Altringham, James / Fumero, Emilio / Wilcox, Mark H / Buckley, Anthony M

    Frontiers in microbiology

    2022  Volume 13, Page(s) 901911

    Abstract: Treatment for moderate-to-severe acne vulgaris relies on prolonged use of oral tetracycline-class antibiotics; however, these broad-spectrum antibiotics are often associated with off-target effects and negative gastrointestinal sequelae. Sarecycline is a ...

    Abstract Treatment for moderate-to-severe acne vulgaris relies on prolonged use of oral tetracycline-class antibiotics; however, these broad-spectrum antibiotics are often associated with off-target effects and negative gastrointestinal sequelae. Sarecycline is a narrow-spectrum antibiotic treatment option. Here, we investigated the effect of prolonged sarecycline exposure, compared with broad-spectrum tetracyclines (doxycycline and minocycline) upon the colonic microbiota. Three
    Language English
    Publishing date 2022-05-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.901911
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  9. Article ; Online: Longitudinal Impact of Life Events on Adolescent Binge Drinking in the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA).

    Nooner, Kate B / De Bellis, Michael D / Clark, Duncan B / Thompson, Wesley K / Brumback, Ty

    Substance use & misuse

    2020  Volume 55, Issue 11, Page(s) 1846–1855

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adolescent ; Alcohol Drinking ; Binge Drinking ; Female ; Humans ; Logistic Models ; Longitudinal Studies ; Male ; Surveys and Questionnaires ; Underage Drinking
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1310358-1
    ISSN 1532-2491 ; 1082-6084
    ISSN (online) 1532-2491
    ISSN 1082-6084
    DOI 10.1080/10826084.2020.1768549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Is there a 24-hour rhythm in alcohol craving and does it vary by sleep/circadian timing?

    Hisler, Garrett C / Rothenberger, Scott D / Clark, Duncan B / Hasler, Brant P

    Chronobiology international

    2020  Volume 38, Issue 1, Page(s) 109–121

    Abstract: Increasing evidence implicates sleep/circadian factors in alcohol use; however, the role of such factors in alcohol craving has received scant attention. Prior research suggests a 24-hour rhythm in related processes (e.g., reward motivation), but more ... ...

    Abstract Increasing evidence implicates sleep/circadian factors in alcohol use; however, the role of such factors in alcohol craving has received scant attention. Prior research suggests a 24-hour rhythm in related processes (e.g., reward motivation), but more research directly investigating a rhythm in craving is needed. Moreover, prior evidence is ambiguous whether such a rhythm in alcohol craving may vary by sleep/circadian timing. To examine these possibilities, 36 late adolescents (18-22 years of age; 61% female) with regular alcohol use but without a current alcohol use disorder were recruited to complete smartphone reports of alcohol craving intensity six times a day for two weeks. During these two weeks, participants wore wrist actigraphs and completed two in-lab assessments (on Thursday and Sunday) of dim light melatonin onset (DLMO). Average actigraphically derived midpoint of sleep on weekends and average DLMO were used as indicators of sleep and circadian timing, respectively. Multilevel cosinor analysis revealed a 24-hour rhythm in alcohol craving. Findings across the sleep and circadian timing variables converged to suggest that sleep/circadian timing moderated the 24-hour rhythm in alcohol craving. Specifically, people with later sleep/circadian timing had later timing of peak alcohol craving. These findings add to the growing evidence of potential circadian influences on reward-related phenomena and suggest that greater consideration of sleep and circadian influences on alcohol craving may be useful for understanding alcohol use patterns and advancing related interventions.
    MeSH term(s) Adolescent ; Alcohol Drinking ; Circadian Rhythm ; Craving ; Female ; Humans ; Male ; Melatonin ; Middle Aged ; Sleep
    Chemical Substances Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2020-11-09
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2020.1838532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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