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  1. Article ; Online: Overuse of long-acting β

    Brunton, Stephen A / Hogarth, D Kyle

    Postgraduate medicine

    2024  Volume 135, Issue 8, Page(s) 784–802

    Abstract: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality globally. In the major revision of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report, the scientific committee concluded that ...

    Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality globally. In the major revision of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report, the scientific committee concluded that the use of long-acting β
    MeSH term(s) Humans ; Adrenergic beta-2 Receptor Agonists/therapeutic use ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Muscarinic Antagonists/therapeutic use ; Administration, Inhalation ; Drug Therapy, Combination ; Adrenal Cortex Hormones/therapeutic use ; Dyspnea/chemically induced ; Dyspnea/drug therapy ; Bronchodilator Agents/therapeutic use
    Chemical Substances Adrenergic beta-2 Receptor Agonists ; Muscarinic Antagonists ; Adrenal Cortex Hormones ; Bronchodilator Agents
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 410138-8
    ISSN 1941-9260 ; 0032-5481
    ISSN (online) 1941-9260
    ISSN 0032-5481
    DOI 10.1080/00325481.2023.2284650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.407: Show issues Location:
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  2. Article ; Online: The role of bronchoscopy as a novel approach in preoperative lung marking for early-stage lung cancer.

    Potts, Kyle / Ravikumar, Nakul / Hogarth, D Kyle / Wagh, Ajay

    Translational cancer research

    2023  Volume 12, Issue 2, Page(s) 221–225

    Language English
    Publishing date 2023-02-01
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-22-2827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Use of augmented fluoroscopic imaging during diagnostic bronchoscopy.

    Hogarth, D Kyle

    Future oncology (London, England)

    2018  Volume 14, Issue 22, Page(s) 2247–2252

    Abstract: The single pulmonary nodule evaluation is a complex problem. In particular, attempts to biopsy peripheral nodules with bronchoscopy have been hampered by difficulty navigating to the correct airway and then confirming the instruments' proximity to the ... ...

    Abstract The single pulmonary nodule evaluation is a complex problem. In particular, attempts to biopsy peripheral nodules with bronchoscopy have been hampered by difficulty navigating to the correct airway and then confirming the instruments' proximity to the nodule. Virtual systems in use do not provide real-time feedback of a live image of the nodule in question. Fluoroscopy has traditionally offered limited assistance as often the nodule is not visible and provides no information on airways/pathways to the nodule. We describe the use of LungVision augmented fluoroscopy to aid in real-time navigation assistance to peripheral lung nodules.
    MeSH term(s) Bronchoscopy/methods ; Fluoroscopy/methods ; Humans ; Intraoperative Period ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/surgery ; Radiographic Image Enhancement/methods ; Software ; Solitary Pulmonary Nodule/diagnostic imaging ; Solitary Pulmonary Nodule/pathology
    Language English
    Publishing date 2018-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2184533-5
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2017-0686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Bronchoscopic lung volume reduction in emphysema: a review.

    Ravikumar, Nakul / Wagh, Ajay / Holden, Van K / Hogarth, D Kyle

    Current opinion in pulmonary medicine

    2023  Volume 30, Issue 1, Page(s) 58–67

    Abstract: Purpose of review: Chronic obstructive pulmonary disease (COPD) poses a substantial burden on the healthcare system and is currently considered the sixth leading cause of death in the United States. Emphysema, as evidenced by severe air-trapping in ... ...

    Abstract Purpose of review: Chronic obstructive pulmonary disease (COPD) poses a substantial burden on the healthcare system and is currently considered the sixth leading cause of death in the United States. Emphysema, as evidenced by severe air-trapping in patients with COPD, leads to significant dyspnea and morbidity. Lung volume reduction via surgery or minimally invasive endobronchial interventions are currently available, which improve lung function and quality of life.
    Recent findings: Newer studies have noted a survival benefit in patients post bronchoscopic lung volume reduction vs. those subjected to standard of care. The presence of collateral ventilation is one of the most common impeding factors to placing endobronchial valves, and if placed, these patients might not achieve lobar atelectasis; however, there are newer modalities that are now available for patients with collateral ventilation which we have described.
    Summary: Combining standard of care treatment that includes smoking cessation, bronchodilators, preventive care including vaccinations, pulmonary rehabilitation, and endobronchial treatment using various interventions in decreasing hyperinflation improves quality of life and may improve survival and hence significantly reduce the burden of COPD on healthcare.
    MeSH term(s) Humans ; Pneumonectomy ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Emphysema/etiology ; Pulmonary Emphysema/surgery ; Quality of Life ; Treatment Outcome
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000001031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4900: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: The Society for Advanced Bronchoscopy: An Introduction.

    Hogarth, D Kyle / Mahajan, Amit K

    Chest

    2019  Volume 155, Issue 6, Page(s) 1092–1094

    MeSH term(s) Bronchoscopy/methods ; Bronchoscopy/trends ; Education ; Humans ; International Cooperation ; Lung Diseases/diagnosis ; Lung Diseases/therapy ; Organizational Objectives ; Pulmonary Medicine/education ; Pulmonary Medicine/standards ; Pulmonary Medicine/trends ; Quality Improvement/organization & administration ; Research ; Societies, Medical/organization & administration
    Language English
    Publishing date 2019-02-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2019.02.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
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    Zs.MO 349: Show issues

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  6. Article: Robotic bronchoscopy for pulmonary lesions: a review of existing technologies and clinical data.

    Agrawal, Abhinav / Hogarth, D Kyle / Murgu, Septimiu

    Journal of thoracic disease

    2020  Volume 12, Issue 6, Page(s) 3279–3286

    Abstract: Bronchoscopic interventions are preferred for sampling suspicious pulmonary lesions as they have lower complications and can achieve diagnosis and staging in one single procedure. Limitations in existing guided bronchoscopy platforms has led to ... ...

    Abstract Bronchoscopic interventions are preferred for sampling suspicious pulmonary lesions as they have lower complications and can achieve diagnosis and staging in one single procedure. Limitations in existing guided bronchoscopy platforms has led to developments in robotic assisted technologies. These devices may allow the bronchoscopist to more precisely maneuver the scope and instruments into the periphery of the lungs under direct visualization while also ensuring stability during sampling of the target lesions. These devices have the potential to improve the diagnostic yield in sampling peripheral lung lesions and may play a role in the treatment of non-operable or oligometastatic peripheral tumors using bronchoscopic ablative therapies. In this article, we review the existing robotic bronchoscopy technologies and summarize the available pre-clinical and clinical data supporting their use.
    Language English
    Publishing date 2020-05-12
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2020.03.35
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Perspective on airway stenting in inoperable patients with tracheoesophageal fistula after curative-intent treatment for esophageal cancer.

    Chaddha, Udit / Hogarth, D Kyle / Murgu, Septimiu

    Journal of thoracic disease

    2019  Volume 11, Issue 5, Page(s) 2165–2174

    Language English
    Publishing date 2019-06-25
    Publishing country China
    Document type Editorial
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.12.128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Microwave ablation via a flexible catheter for the treatment of nonsurgical peripheral lung cancer: A pilot study.

    Xie, Fangfang / Chen, Junxiang / Jiang, Yifeng / Sun, Jiayuan / Hogarth, D Kyle / Herth, Felix J F

    Thoracic cancer

    2022  Volume 13, Issue 7, Page(s) 1014–1020

    Abstract: Background: Endobronchial microwave ablation via flexible catheter offers the potential for local therapy for inoperable peripheral lung cancer. The study aimed to evaluate the feasibility and safety of navigation bronchoscopy-guided water-cooled ... ...

    Abstract Background: Endobronchial microwave ablation via flexible catheter offers the potential for local therapy for inoperable peripheral lung cancer. The study aimed to evaluate the feasibility and safety of navigation bronchoscopy-guided water-cooled microwave ablation catheter for nonsurgical peripheral lung cancer.
    Methods: This was a prospective single arm pilot study. Patients with early stage or multiple primary peripheral lung cancer who were nonsurgical candidates for surgery were enrolled in the study. Bronchoscopic microwave ablation was performed via a flexible water-cooled microwave ablation antenna under the guidance of navigation bronchoscopy. Radial probe endobronchial ultrasound combined with fluoroscopy was used to confirm the position. Treatment outcomes were evaluated based on follow-up chest CT and positron emission tomography scans. Primary endpoints were technical success and safety. Secondary endpoints were complete ablation rate, 2-year local control rate, and progression-free survival.
    Results: Thirteen patients were enrolled in the study from April 2018 to July 2019. A total of 19 sessions of microwave ablation were performed on 14 tumors under the guidance of navigation bronchoscopy. The technical success was 100%. Treatment-related complications occurred in two patients. The complete ablation rate was 78.6% (11/14). The 2-year local control rate was 71.4%. Median progression-free survival was 33 months for all patients.
    Conclusions: In this pilot study, bronchoscopic microwave ablation appears to be feasible with acceptable occurrence of complication in the treatment of peripheral lung cancer under the guidance of navigation bronchoscopy.
    MeSH term(s) Catheter Ablation/methods ; Catheters ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Microwaves/therapeutic use ; Pilot Projects ; Prospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-02-14
    Publishing country Singapore
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2625856-0
    ISSN 1759-7714 ; 1759-7706
    ISSN (online) 1759-7714
    ISSN 1759-7706
    DOI 10.1111/1759-7714.14351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6921: Show issues Location:
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  9. Article ; Online: An NP's guide to diagnosing and treating alpha-1 antitrypsin deficiency.

    Newell, Judith A / Donahue, Christine / Hogarth, D Kyle

    The Nurse practitioner

    2019  Volume 44, Issue 4, Page(s) 13–21

    Abstract: As NPs play an increasingly vital role in primary care, they must be well versed in a variety of conditions. Alpha-1 antitrypsin (AAT) deficiency is a respiratory disease for which there is particularly low awareness in both the nursing profession and ... ...

    Abstract As NPs play an increasingly vital role in primary care, they must be well versed in a variety of conditions. Alpha-1 antitrypsin (AAT) deficiency is a respiratory disease for which there is particularly low awareness in both the nursing profession and the wider medical community. This article provides an overview of AAT deficiency and includes guidance for diagnosing the disease.
    Language English
    Publishing date 2019-03-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604085-8
    ISSN 1538-8662 ; 0361-1817
    ISSN (online) 1538-8662
    ISSN 0361-1817
    DOI 10.1097/01.NPR.0000554086.13073.ec
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2398: Show issues Location:
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  10. Article: The role of endobronchial ultrasound transbronchial needle aspiration for programmed death ligand 1 testing and next generation sequencing in advanced non-small cell lung cancer.

    Chaddha, Udit / Hogarth, D Kyle / Murgu, Septimiu

    Annals of translational medicine

    2019  Volume 7, Issue 15, Page(s) 351

    Abstract: Guidelines recommend testing for driver mutations and programmed death ligand 1 (PD-L1) expression at the time of initial diagnosis and during disease progression to help determine prognosis and initiate personalized therapy. In this article we review ... ...

    Abstract Guidelines recommend testing for driver mutations and programmed death ligand 1 (PD-L1) expression at the time of initial diagnosis and during disease progression to help determine prognosis and initiate personalized therapy. In this article we review the updated literature and techniques of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) in obtaining adequate tissue for molecular analysis by using next-generation sequencing (NGS) and for assessing PD-L1 expression through immunohistochemistry.
    Language English
    Publishing date 2019-08-26
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2019.03.35
    Database MEDical Literature Analysis and Retrieval System OnLINE

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