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  1. Article ; Online: Bhimamycin J, a Rare Benzo[f]isoindole-dione Alkaloid from the Marine-Derived Actinomycete Streptomyces sp. MS180069.

    Song, Fuhang / Yang, Na / Khalil, Zeinab G / Salim, Angela A / Han, Jiahui / Bernhardt, Paul V / Lin, Rui / Xu, Xiuli / Capon, Robert J

    Chemistry & biodiversity

    2021  Volume 18, Issue 11, Page(s) e2100674

    Abstract: ... collected from the South China Sea, yielded the new benzo[f]isoindole-dione alkaloid, bhimamycin J (1 ...

    Abstract Chemical investigation on a Streptomyces sp. strain MS180069 isolated from a sediment sample collected from the South China Sea, yielded the new benzo[f]isoindole-dione alkaloid, bhimamycin J (1). The structure was determined by extensive spectroscopic analysis, including HRMS, 1D, 2D NMR, and X-ray diffraction techniques. A molecular docking study revealed 1 as a new molecular motif that binds with human angiotensin converting enzyme2 (ACE2), recently described as the cell surface receptor responsible for uptake of 2019-CoV-2. Using enzyme assays we confirm that 1 inhibits human ACE2 79.7 % at 25 μg/mL.
    MeSH term(s) Alkaloids/chemistry ; Alkaloids/metabolism ; Alkaloids/pharmacology ; Alkaloids/therapeutic use ; Angiotensin-Converting Enzyme 2/antagonists & inhibitors ; Angiotensin-Converting Enzyme 2/metabolism ; Binding Sites ; COVID-19/drug therapy ; COVID-19/virology ; Fungi/drug effects ; Geologic Sediments/microbiology ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Humans ; Isoindoles/chemistry ; Isoindoles/isolation & purification ; Isoindoles/metabolism ; Isoindoles/pharmacology ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Molecular Docking Simulation ; SARS-CoV-2/isolation & purification ; Streptomyces/chemistry ; Streptomyces/isolation & purification ; Streptomyces/metabolism
    Chemical Substances Alkaloids ; Isoindoles ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Language English
    Publishing date 2021-10-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202100674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Percutaneous antegrade removal of double J ureteral stents via a 9-F nephrostomy route.

    Shin, Ji Hoon / Yoon, Hyun-Ki / Ko, Gi-Young / Sung, Kyu-Bo / Song, Ho-Young / Choi, Eugene / Kim, Jin Hyoung / Kim, Jae Wook / Kim, Kyung-Rae / Kwon, Jaehyun

    Journal of vascular and interventional radiology : JVIR

    2007  Volume 18, Issue 9, Page(s) 1156–1161

    Abstract: ... of double J ureteral stents via preexisting nondilated nephrostomy routes under fluoroscopic guidance ... respectively, all of which resolved spontaneously.: Conclusions: Percutaneous antegrade removal of double J ...

    Abstract Purpose: To evaluate the safety and clinical efficacy of an antegrade approach in the removal of double J ureteral stents via preexisting nondilated nephrostomy routes under fluoroscopic guidance.
    Materials and methods: Under fluoroscopic guidance and local anesthesia, antegrade removal of 39 ureteral stents in 27 patients was attempted by using a snare or basket. Indications for percutaneous stent removal included the presence of a preexisting nephrostomy route (n = 8), a surgical history resulting in an inaccessible retrograde route (n = 8), urethral stricture (n = 5), upward stent migration (n = 2), inability to obtain a lithotomy position (n = 1), fragmentation of the proximal stent (n = 1), and inability to find the ureteral orifice with a cystoscope (n = 2).
    Results: Thirty-seven of the 39 stents (95%) were successfully removed by using a snare or basket. Two stents (5.1%) could not be removed with a snare or basket because they were embedded against the renal calyx or pelvis. There were no major complications. Blood clot formation or laceration or tract leakage of the pelvicalyceal system occurred in six and two patients, respectively, all of which resolved spontaneously.
    Conclusions: Percutaneous antegrade removal of double J ureteral stents with a snare or basket via a nondilated nephrostomy route is effective without major complications in patients with an available nephrostomy route or an inaccessible retrograde option.
    MeSH term(s) Adult ; Aged ; Device Removal/methods ; Female ; Humans ; Male ; Middle Aged ; Nephrostomy, Percutaneous/methods ; Radiography, Interventional/methods ; Stents ; Ureter/diagnostic imaging ; Ureter/surgery ; Ureteral Obstruction/diagnostic imaging ; Ureteral Obstruction/therapy ; Urography/methods
    Language English
    Publishing date 2007-09
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2007.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: The joint angular distribution of B s → J/[psi][phi] with subsequent decays F → [rho][pi] and J/[psi] → l + l -

    Kramer, Gustav / Song, He-Shan / Yu, Chaehyun

    (DESY ; 02,71)

    2002  

    Author's details G. Kramer; H. S. Song; C. Yu. Deutsches Elektronen-Synchrotron, DESY
    Series title DESY ; 02,71
    Language English
    Size Online-Ressource (8 S., 354,1 KB), graph. Darst., 30 cm
    Publisher Technische Informationsbibliothek u. Universitätsbibliothek ; DESY
    Publishing place Hannover ; Hamburg
    Document type Book ; Online
    Note Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book: The joint angular distribution of B s → J/[psi][phi] with subsequent decays F → [rho][pi] and J/[psi] → l + l -

    Kramer, Gustav / Song, He-Shan / Yu, Chaehyun

    (DESY ; 02,71)

    2002  

    Author's details G. Kramer; H. S. Song; C. Yu. Deutsches Elektronen-Synchrotron, DESY
    Series title DESY ; 02,71
    Language English
    Size 9 Sp, graph. Darst, 30 cm
    Publisher DESY
    Publishing place Hamburg
    Document type Book
    Note Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book: The joint angular distribution of B s → J/[psi][phi] with subsequent decays F → [rho][pi] and J/[psi] → l + l -

    Kramer, Gustav / Song, He-Shan / Yu, Chaehyun

    (DESY ; 02,71)

    2002  

    Author's details G. Kramer; H. S. Song; C. Yu. Deutsches Elektronen-Synchrotron, DESY
    Series title DESY ; 02,71
    Language English
    Size 9 Sp, graph. Darst, 30 cm
    Publisher DESY
    Publishing place Hamburg
    Document type Book
    Note Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Article: [The role of CD4

    Zhou, Y / Song, F / Luo, J

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2023  Volume 58, Issue 3, Page(s) 225–232

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Animals ; Rats ; Forkhead Transcription Factors ; Myelin P0 Protein ; Rats, Sprague-Dawley ; T-Lymphocytes, Regulatory ; CD4 Antigens/immunology ; Interleukin-2 Receptor alpha Subunit/immunology
    Chemical Substances Forkhead Transcription Factors ; Myelin P0 Protein ; CD4 Antigens ; Interleukin-2 Receptor alpha Subunit
    Language Chinese
    Publishing date 2023-03-04
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20220412-00183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Comparison of electrophysiological properties of parvalbumin neurons in the tail of the striatum and the auditory cortex of mice].

    You, J / Song, C / Liang, F

    Nan fang yi ke da xue xue bao = Journal of Southern Medical University

    2023  Volume 42, Issue 12, Page(s) 1889–1895

    Abstract: ... onset, rheobase, average firing rate, F/I slope and spike frequency adaptation (SFA); the waveform ...

    Abstract Objective: To study the electrophysiological properties of parvalbumin (PV) neurons in the auditory cortex (AC) and its descending auditory projection area in the tail of the striatum (TS).
    Methods: The stimulation response of PV neuron step current was recorded in PV-Cre-Ai14 mice using in vitro patch clamp technique, and the release characteristics and waveform characteristics of PV neuron action potentials (APs) were analyzed using Clampfit and MATLAB software. The release characteristics of the APs included AP onset, rheobase, average firing rate, F/I slope and spike frequency adaptation (SFA); the waveform characteristics included peak and post potential characteristics.
    Results: The PV neurons of the TS and the AC had significantly different electrophysiological characteristics. In terms of peak potential characteristics, the PV neurons in the TS presented with smaller half peak width (
    Conclusion: The PV neurons in the TS and the AC of mice show significantly different electrophysiological characteristics in processing auditory information.
    MeSH term(s) Mice ; Animals ; Auditory Cortex/metabolism ; Parvalbumins/metabolism ; Neurons/metabolism ; Action Potentials/physiology ; Patch-Clamp Techniques
    Chemical Substances Parvalbumins
    Language Chinese
    Publishing date 2023-01-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2250951-3
    ISSN 1673-4254
    ISSN 1673-4254
    DOI 10.12122/j.issn.1673-4254.2022.12.19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Determination of dimethyl oxalate and diethyl oxalate in workplace air by high performance liquid chromatography].

    Chen, Z L / Wang, M / Jiang, J F / Song, W L

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2024  Volume 42, Issue 3, Page(s) 199–202

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Chromatography, High Pressure Liquid/methods ; Air Pollutants, Occupational/analysis ; Workplace ; Oxalates/analysis
    Chemical Substances Air Pollutants, Occupational ; Oxalates
    Language Chinese
    Publishing date 2024-03-25
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20230209-00039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Progress in relationship between long non-coding RNA and myocardial ischemia-reperfusion injury].

    Li, C J / Song, X W / Guo, Z F

    Zhonghua xin xue guan bing za zhi

    2023  Volume 52, Issue 1, Page(s) 96–102

    MeSH term(s) Humans ; Myocardial Reperfusion Injury/genetics ; RNA, Long Noncoding/genetics ; Myocytes, Cardiac ; Apoptosis ; Myocardial Ischemia
    Chemical Substances RNA, Long Noncoding
    Language Chinese
    Publishing date 2023-05-15
    Publishing country China
    Document type Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20231009-00278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Impact of multi-leaf collimator positioning accuracy on quality control of volumetric modulation arc therapy plan for cervical cancer treated with Elekta linear accelerator].

    Liang, J / Yu, F / Zhu, J / Song, T

    Nan fang yi ke da xue xue bao = Journal of Southern Medical University

    2022  Volume 42, Issue 7, Page(s) 1089–1094

    Abstract: Objective: To investigate the influence of positioning accuracy of the multi-leaf collimators (MLC) on the passing rate of the plan dose verification for volumetric modulation arc therapy (VMAT) of cervical cancer using an Elekta linear accelerator.: ... ...

    Abstract Objective: To investigate the influence of positioning accuracy of the multi-leaf collimators (MLC) on the passing rate of the plan dose verification for volumetric modulation arc therapy (VMAT) of cervical cancer using an Elekta linear accelerator.
    Methods: The dose distributions were measured using Sun Nuclear's Mapcheck and Arccheck semiconductors matrix before and after MLC calibration in30 cervical cancer patients undergoing VMAT. Dosimetric comparisons were performed with 2D and 3D gamma passing rates of 3%, 3 mm and 2%, and 2 mm. The 3D gamma distribution was reconstructed with respect to the patient's anatomy using 3DVH software to evaluate the possible influence of MLC positioning accuracy.
    Results: Before and after MLC calibration, the gamma passing rates of Mapcheck were (88.80±1.81)% and (99.25 ± 0.53)% under 3% and 3 mm standard, respectively, with an average increase of 10.45%. The corresponding gamma passing rates of Arccheck were (87.61±1.98)% and (98.13±0.99)%, respectively, with an average increase of 10.52%. The gamma passing rates of 3DVH were (89.87±2.28)% and (98.3±1.15)%, respectively, with an average increase of 8.43%.
    Conclusion: The MLC positioning accuracy is one of the main factors influencing dosimetric accuracy of VMAT for cervical cancer. The application of Autocal software facilitates MLC calibration and improves the accuracy and safety of VMAT delivery for cervical cancer.
    MeSH term(s) Female ; Humans ; Particle Accelerators ; Quality Control ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy, Intensity-Modulated/methods ; Uterine Cervical Neoplasms/radiotherapy
    Language Chinese
    Publishing date 2022-02-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 2250951-3
    ISSN 1673-4254
    ISSN 1673-4254
    DOI 10.12122/j.issn.1673-4254.2022.07.19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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