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  1. Article ; Online: Design and Atroposelective Construction of IAN analogues by Organocatalytic Asymmetric Heteroannulation of Alkynes.

    Zhang, Lei / Shen, Jiahua / Wu, San / Zhong, Guofu / Wang, Yong-Bin / Tan, Bin

    Angewandte Chemie (International ed. in English)

    2020  Volume 59, Issue 51, Page(s) 23077–23082

    Abstract: An organocatalytic atroposelective strategy for accessing enantioenriched axially chiral IAN ... tolerated a broad substrate scope, providing a facile organocatalytic approach to IAN analogues in good ... of this methodology was illustrated through further transformations into IAN-type ligand and axially chiral thiourea. ...

    Abstract An organocatalytic atroposelective strategy for accessing enantioenriched axially chiral IAN analogues was developed for the first time. A class of novel atropisomeric C2-arylquinoline skeletons were synthesized with high enantiocontrol via chiral phosphoric-acid-catalyzed heteroannulation of in situ generated vinylidene ortho-quinone methide (VQM) intermediates with ortho-aminophenones. The strategy tolerated a broad substrate scope, providing a facile organocatalytic approach to IAN analogues in good yields and excellent enantioselectivities under mild reaction conditions. Moreover, the synthetic utility of this methodology was illustrated through further transformations into IAN-type ligand and axially chiral thiourea.
    Language English
    Publishing date 2020-10-15
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202010598
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  2. Article: Screen-Printed Sensors Modified with Nafion and Mesoporous Carbon for Electrochemical Detection of Lead in Blood.

    Boselli, Elena / Wu, Zhizhen / Haynes, Erin N / Papautsky, Ian

    Journal of the Electrochemical Society

    2024  Volume 171, Issue 2, Page(s) 27513

    Abstract: Lead (Pb) has long been acknowledged as a systemic toxicant, with pronounced health impacts observed even at low exposure levels, particularly in children. Adverse effects include diminished cognitive function, altered behavior, and developmental delays. ...

    Abstract Lead (Pb) has long been acknowledged as a systemic toxicant, with pronounced health impacts observed even at low exposure levels, particularly in children. Adverse effects include diminished cognitive function, altered behavior, and developmental delays. Consequently, it is imperative to conduct regular monitoring of Blood Lead Levels (BLLs). In this work, we report on an electrochemical sensor based on screen-printed carbon electrode (SPCE) coated with Nafion and mesoporous carbon (MC). The sensor system uses simple sample preparation (acidification and dilution of whole blood), minimal sample volume (a few blood drops, 200
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ISSN 0013-4651
    ISSN 0013-4651
    DOI 10.1149/1945-7111/ad2397
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  3. Article ; Online: Persistent myopericarditis after heterologous SARS-CoV-2 mRNA vaccination.

    Wu, Kai Yi / Butler, Craig R / Koshman, Sheri / Oudit, Gavin Y / Ian Paterson, D

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2023  Volume 195, Issue 16, Page(s) E584–E587

    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Vaccination ; RNA, Messenger ; Antibodies, Viral
    Chemical Substances RNA, Messenger ; Antibodies, Viral
    Language English
    Publishing date 2023-05-05
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.221510
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  4. Article ; Online: High density electron doping in boron-doped twisted bilayer graphene: a ladder to extended flat-band.

    Tanwar, Khagesh / Wu, Xi / Tan, Xin / Smith, Sean C / Li, Jia / Chen, Ying Ian

    Materials horizons

    2024  Volume 11, Issue 4, Page(s) 1046–1053

    Abstract: Realizing Von Hove singularity (VHS) and extended flat bands of graphene near the Fermi level ( ...

    Abstract Realizing Von Hove singularity (VHS) and extended flat bands of graphene near the Fermi level (
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2744250-0
    ISSN 2051-6355 ; 2051-6347
    ISSN (online) 2051-6355
    ISSN 2051-6347
    DOI 10.1039/d3mh01213a
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  5. Article ; Online: Automated protocols for delineating human hippocampal subfields from 3 Tesla and 7 Tesla magnetic resonance imaging data.

    Hickling, Alice L / Clark, Ian A / Wu, Yan I / Maguire, Eleanor A

    Hippocampus

    2024  

    Abstract: Researchers who study the human hippocampus are naturally interested in how its subfields function. However, many researchers are precluded from examining subfields because their manual delineation from magnetic resonance imaging (MRI) scans (still the ... ...

    Abstract Researchers who study the human hippocampus are naturally interested in how its subfields function. However, many researchers are precluded from examining subfields because their manual delineation from magnetic resonance imaging (MRI) scans (still the gold standard approach) is time consuming and requires significant expertise. To help ameliorate this issue, we present here two protocols, one for 3T MRI and the other for 7T MRI, that permit automated hippocampus segmentation into six subregions, namely dentate gyrus/cornu ammonis (CA)4, CA2/3, CA1, subiculum, pre/parasubiculum, and uncus along the entire length of the hippocampus. These protocols are particularly notable relative to existing resources in that they were trained and tested using large numbers of healthy young adults (n = 140 at 3T, n = 40 at 7T) whose hippocampi were manually segmented by experts from MRI scans. Using inter-rater reliability analyses, we showed that the quality of automated segmentations produced by these protocols was high and comparable to expert manual segmenters. We provide full open access to the automated protocols, and anticipate they will save hippocampus researchers a significant amount of time. They could also help to catalyze subfield research, which is essential for gaining a full understanding of how the hippocampus functions.
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074352-2
    ISSN 1098-1063 ; 1050-9631
    ISSN (online) 1098-1063
    ISSN 1050-9631
    DOI 10.1002/hipo.23606
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    Zs.A 3227: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Urachal sinus presenting as an acute umbilical infection.

    Wu, Michael / Carroll, James / Newman, Sheri / Hayes, Ian

    ANZ journal of surgery

    2022  Volume 93, Issue 3, Page(s) 720–721

    MeSH term(s) Humans ; Infections ; Urachal Cyst ; Umbilicus ; Intraabdominal Infections
    Language English
    Publishing date 2022-07-23
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.17924
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    Zs.A 180: Show issues Location:
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  7. Article ; Online: Weight loss and hypergammaglobulinaemia in an elderly man.

    Wang, Samuel Sherng Young / Wu, Ian Qianhuang / Yin, Cecilia / Wang, Shi / de Mel, Sanjay

    Singapore medical journal

    2023  

    Language English
    Publishing date 2023-05-30
    Publishing country India
    Document type Letter
    ZDB-ID 604319-7
    ISSN 2737-5935 ; 0037-5675
    ISSN (online) 2737-5935
    ISSN 0037-5675
    DOI 10.4103/singaporemedj.SMJ-2021-398
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    Zs.B 589: Show issues Location:
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  8. Article ; Online: First-Principles Dynamics of Fluorine Adsorption on Clean and Monohydrogenated Si{001}.

    Wu, Ian Y H / Jenkins, Stephen J

    Langmuir : the ACS journal of surfaces and colloids

    2022  Volume 38, Issue 23, Page(s) 7256–7271

    Abstract: The interaction of highly reactive species with solid surfaces can result in modes of adsorption quite distinct from the classic molecular and dissociative events that are usually thought to dominate. For instance, compelling experimental evidence ... ...

    Abstract The interaction of highly reactive species with solid surfaces can result in modes of adsorption quite distinct from the classic molecular and dissociative events that are usually thought to dominate. For instance, compelling experimental evidence suggests that adsorption of F
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c00740
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  9. Article ; Online: On the Relationship Between Online Heterosexist Discrimination and Mental Health and Substance Use Among LGBTQ+ Young Adults.

    Carson, Ian / Wu, Wei / Knopf, Amy / Crawford, Christopher Andrew / Zapolski, Tamika C B

    Archives of sexual behavior

    2024  Volume 53, Issue 4, Page(s) 1277–1291

    Abstract: LGBTQ+ individuals experience disproportionately higher rates of mental health and substance use difficulties. Discrimination is a significant factor in explaining these disparities. Meyer's (2003) minority stress theory (MST) indicates that proximal ... ...

    Abstract LGBTQ+ individuals experience disproportionately higher rates of mental health and substance use difficulties. Discrimination is a significant factor in explaining these disparities. Meyer's (2003) minority stress theory (MST) indicates that proximal group-specific processes mediate the relationship between discrimination and health outcomes, with the effects moderated by other social factors. However, online discrimination has been understudied among LGBTQ+  people. Focusing on LGBTQ+  young adults experiencing online heterosexist discrimination (OHD), the current study aimed to investigate the effect of OHD on mental health outcomes and explore whether the effect was mediated by proximal factors of internalized heterosexism, online concealment, and acceptance concerns and moderated by social support. Path analysis was used to examine the effects. A total of 383 LGBTQ+  young adults (18-35) from an introductory psychology subject pool, two online crowdsourcing platforms, and the community completed a questionnaire assessing these constructs. OHD was associated with increased psychological distress and cannabis use. Two proximal stressors (acceptance concerns and sexual orientation concealment) mediated the relationship between OHD and psychological distress. Sexual orientation concealment also mediated the relationship between OHD and cannabis use. There was no evidence that online social support from LGBTQ+ peers moderated any of the relationships. MST is a viable guiding framework for exploring OHD. Acceptance concerns and online concealment are important constructs to consider and may be potential treatment targets for individuals experiencing psychological distress or engaging in cannabis use due to OHD.
    MeSH term(s) Humans ; Male ; Female ; Young Adult ; Mental Health ; Stress, Psychological/psychology ; Sexual and Gender Minorities ; Minority Groups/psychology ; Substance-Related Disorders/psychology
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 184221-3
    ISSN 1573-2800 ; 0004-0002
    ISSN (online) 1573-2800
    ISSN 0004-0002
    DOI 10.1007/s10508-023-02800-6
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    Zs.A 1106: Show issues Location:
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  10. Article ; Online: Maximising the informativeness of new records in spatial sampling design

    Ian Flint / Chung‐Huey Wu / Roozbeh Valavi / Wan‐Jyun Chen / Te‐En Lin

    Methods in Ecology and Evolution, Vol 15, Iss 1, Pp 178-

    2024  Volume 190

    Abstract: Abstract In building a robust knowledge base or validating existing models for use in ecological spatial modelling, having plentiful high‐quality data is paramount. Careful survey design helps attain that goal and, in part due to financial constraints, ... ...

    Abstract Abstract In building a robust knowledge base or validating existing models for use in ecological spatial modelling, having plentiful high‐quality data is paramount. Careful survey design helps attain that goal and, in part due to financial constraints, such design requires the balancing of hard monetary costs and the intangible benefit of improved ecological models. We propose a framework that quantifies a location's value to the modeller by accounting for both the probability of obtaining new samples and their expected contribution to the model. The approach is illustrated on a citizen science database of roadkills in Taiwan, modelled as a Poisson point process on a linear road network. Our method has revealed some valuable locations that were not self‐evident, for example, highlighting the possibility of sending volunteers to mountainous areas that despite being hard to reach, would provide valuable samples. We have also highlighted some ex situ sampling opportunities to avoid wasting resources by over‐sampling hard to access locations. Our technique is not restricted to presence‐only data, and in fact we present a general framework that can be applied to a wide range of settings by tuning its formulation. Our method is quite flexible and allows for more elaborate value functions, enabling managers to precisely quantify varied goals within the same framework.
    Keywords ecological modelling ; linear network ; Poisson point process ; presence‐only models ; sampling bias ; spatial modelling ; Ecology ; QH540-549.5 ; Evolution ; QH359-425
    Subject code 310
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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