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Article ; Online: Nonreciprocal Goos-Hänchen shift in a Dirac semimetal based asymmetric photonic crystal structure.

Hu, Pengya / Zhou, Jun / Song, Qi / Da, Haixia

Applied optics

2024 Volume 63, Issue 2, Page(s) 459–466

Abstract: The generation and control of the Goos-Hänchen (GH) shift is a vital step toward its realistic applications, but investigations have mainly been limited to the directional-dependent ones; i.e., the GH shift is reciprocal for two opposite propagating ... ...

Abstract	The generation and control of the Goos-Hänchen (GH) shift is a vital step toward its realistic applications, but investigations have mainly been limited to the directional-dependent ones; i.e., the GH shift is reciprocal for two opposite propagating directions. Here, by designing the asymmetrical multilayered structure with three-dimensional bulky Dirac semimetal (BDS) films, we theoretically confirm the footprint of the pronounced directional-dependent GH shift, and that it can be switched by the Fermi energy of the BDS. In addition to this electric field induced switching, the period numbers of the unit cells in the asymmetrical structure can also modulate the directional-dependent GH shift. The asymmetrical feature of the multilayered structure dominantly causes the emergence of the directional-dependent GH shift. Our discovery related to the directional-dependent GH shift constitutes an important ingredient for directional-dependent optophotonic devices such as directional sensors, optical switches, and detectors.
Language	English
Publishing date	2024-01-16
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.506487
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Access to oral health care for children with fetal alcohol spectrum disorder: a cross-sectional study.

Hu, Katie / Da Silva, Keith

BMC oral health

2022 Volume 22, Issue 1, Page(s) 497

Abstract: Background: Individuals with developmental disabilities, including Fetal Alcohol Spectrum Disorder (FASD), often suffer from poorer oral health than the general population as they experience challenges with accessing care. However, few studies have ... ...

Abstract	Background: Individuals with developmental disabilities, including Fetal Alcohol Spectrum Disorder (FASD), often suffer from poorer oral health than the general population as they experience challenges with accessing care. However, few studies have investigated access to oral health care specific to children diagnosed with FASD. Thus, the objective of this cross-sectional study is to examine the use of oral health care services by children diagnosed with FASD in Saskatchewan, Canada, and to identify perceived barriers that affect their access to oral health care. Methods: Parents or caregivers for children with FASD under the age of 16 were recruited through community organizations. Between July 2020 and January 2021, 189 participants completed a 64-item questionnaire that assessed sociodemographic characteristics, oral health care utilization, and perceived barriers to care. Results: Most children (85%) had visited the dentist within the last 24 months. 55% of children had required sedation for some treatment. 43% of caregivers experienced frustration trying to access care for their child. Common barriers were cost (63%), location (55%), the child's behaviour (78%) and caregiver anxiety (60%). 35% of caregivers believed their dentist lacked adequate knowledge of FASD. Univariate analysis reveals that income, caregiver education, residence location, and insurance status were significantly associated with reporting barriers. Multivariate logistic regression analysis reveals that caregivers who reported a high school education (OR=1.23; 95% CI 1.03 - 1.38); or public insurance (OR=1.33; 95% CI 1.24 - 1.42) or out-of-pocket payments (OR=1.37, 95% CI 1.20 - 1.46); or rural (OR=1.19, 95% CI 1.07 - 1.26) or remote (OR=1.23; 95% CI=1.12 - 1.31) residences were more likely to report difficulties accessing oral health care. Conclusion: Our findings indicate that children with FASD experience various barriers to accessing oral health care. Social determinants of health were significant variables that increased likelihood of barriers. Like other vulnerable populations, cost and clinic location are notable barriers. Oral health care providers' assessment and management of children with FASD are noteworthy for future research.
MeSH term(s)	Child ; Female ; Humans ; Pregnancy ; Caregivers ; Cross-Sectional Studies ; Fetal Alcohol Spectrum Disorders/therapy ; Fetal Alcohol Spectrum Disorders/diagnosis ; Fetal Alcohol Spectrum Disorders/epidemiology ; Health Services Accessibility ; Oral Health ; Social Determinants of Health ; Dental Health Services
Language	English
Publishing date	2022-11-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-022-02561-z
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Article ; Online: The Nazeris fauna in Xizang, China (Coleoptera, Staphylinidae, Paederinae).

Gao, Zhuo-Qun / DA, W A / Hu, Jia-Yao

Zootaxa

2023 Volume 5369, Issue 1, Page(s) 131–145

Abstract: Nine species of Nazeris Fauvel are reported from Xizang, China. Seven of them are described as new: N. mirabilis sp. n., N. dinggyensis sp. n., N. jifuensis sp. n., N. wenxuani sp. n., N. gladius sp. n., N. gyirongensis sp. n. and N. yadongensis sp. n. ... ...

Abstract	Nine species of Nazeris Fauvel are reported from Xizang, China. Seven of them are described as new: N. mirabilis sp. n., N. dinggyensis sp. n., N. jifuensis sp. n., N. wenxuani sp. n., N. gladius sp. n., N. gyirongensis sp. n. and N. yadongensis sp. n. An identification key to the Nazeris species in Xizang and a map showing their distribution are provided.
MeSH term(s)	Animals ; Coleoptera ; China ; Animal Distribution
Language	English
Publishing date	2023-11-08
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5369.1.7
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Article ; Online: Impact of FilmArray respiratory panel test for hospitalized pediatric respiratory tract infection in Taiwan: A 3-year single-center cohort study.

Hu, Jen-Jan / Wang, Da-Ling / Tzeng, I-Shiang

Medicine

2024 Volume 103, Issue 13, Page(s) e37320

Abstract: Respiratory tract infections are prevalent and clinically significant in pediatric populations globally. However, pathogen testing often involves time-consuming processes, resulting in delays in diagnosis. To date, commercial testing machines, such as ... ...

Abstract	Respiratory tract infections are prevalent and clinically significant in pediatric populations globally. However, pathogen testing often involves time-consuming processes, resulting in delays in diagnosis. To date, commercial testing machines, such as the FilmArray respiratory panel, have been proposed for hospitals. Therefore, this study aimed to investigate the impact of the FilmArray respiratory panel at a single center. This study utilized the medical records of our hospital to select pediatric inpatients with respiratory tract infections who underwent the FilmArray respiratory panel between September 2020 and April 2021 and those who did not undergo nucleic acid detection (a rapid test group) between September 2019 and April 2020. FilmArray is a polymerase chain reaction-based diagnostic tool. The FilmArray respiratory panel group was scheduled to recruit 150 patients (final 137 patients), whereas the rapid test group was scheduled to recruit 300 patients (final 267 patients). Differences in continuous variables between the 2 groups were analyzed using independent Student t tests. The FilmArray respiratory panel group had a longer length of inpatient days, longer duration of antibiotic use, and higher proportion of pathogens that tested positive, with significant differences than those in the rapid test group. Fever duration showed no significant difference between the 2 groups. For the polymerase chain reaction method, respiratory syncytial virus was the most commonly detected pathogen causing pneumonia, followed by human rhinovirus/enterovirus and parainfluenza virus. Mycoplasma was detected using the rapid test but not with the FilmArray respiratory panel. The FilmArray respiratory panel provides clinicians with a rapid and useful diagnostic tool. The effect was quite good for virus detection, but not for bacteria. Given its limited adoption, the tool may not aid clinicians in the diagnosis of mild cases.
MeSH term(s)	Humans ; Child ; Viruses/genetics ; Cohort Studies ; Taiwan ; Molecular Diagnostic Techniques/methods ; Respiratory Tract Infections/microbiology ; Respiratory Syncytial Virus, Human
Language	English
Publishing date	2024-03-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000037320
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Article ; Online: Prognosis and clinical significance of Piezo2 in tumor: a meta-analysis and database validation.

Liang, Tong / Wang, Junhong / Zhu, Chenglou / Hu, Yongli / Gao, Zhenhua / Da, Mingxu

Combinatorial chemistry & high throughput screening

2024

Abstract: Objective: The objective of this study is to assess the correlation between Piezo2 and tumors through a comprehensive meta-analysis and database validation.: Methods: Case-control studies investigating the association between Piezo2 and tumors were ... ...

Abstract	Objective: The objective of this study is to assess the correlation between Piezo2 and tumors through a comprehensive meta-analysis and database validation. Methods: Case-control studies investigating the association between Piezo2 and tumors were obtained from various databases, including China National Knowledge Infrastructure (CNKI), SinoMed, Embase, Web of Science, The Cochrane Library, and PubMed. The search was performed from the inception of each database up until May 2023. Two researchers independently screened the literature, extracted data, and assessed the quality of the included studies. Metaanalysis of the included literature was conducted using Stata 12.0 software. Additionally, the Gene Expression Profiling Interactive Analysis (GEPIA) database predicted a correlation between Piezo2 expression and prognostic value in tumor patients. Results: A total of three studies, involving a combined sample size of 392 participants, were included in the meta-analysis. The findings revealed that the expression level of Piezo2 in tumor patients was not significantly associated with age, gender, or tumor size. However, it was found to be positively correlated with lymphatic invasion (OR = 7.89, 95%CI: 3.96-15.73) and negatively correlated with invasion depth (OR = 0.17, 95%CI: 0.06-0.47), TNM stage (OR = 0.48, 95%CI: 0.27-0.87), and histological grade (OR = 0.40, 95%CI: 0.21-0.77). Confirming these findings, the GEPIA database indicated that high expression of Piezo2 was associated with poor prognosis of disease-free survival in patients with colon adenocarcinoma (HR = 1.6, P = 0.049) and gastric cancer (HR = 1.6, P = 0.017). Conclusion: Piezo2 may be associated with poor prognosis and clinicopathological parameters in tumor patients.
Language	English
Publishing date	2024-02-12
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2064785-2
ISSN	1875-5402 ; 1386-2073
ISSN (online)	1875-5402
ISSN	1386-2073
DOI	10.2174/0113862073251440231025111358
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Article ; Online: Bosutinib Stimulates Macrophage Survival, Phagocytosis, and Intracellular Killing of Bacteria.

da Silva, Ronni A G / Stocks, Claudia J / Hu, Guangan / Kline, Kimberly A / Chen, Jianzhu

ACS infectious diseases

2024

Abstract: Host-acting compounds are emerging as potential alternatives to combating antibiotic resistance. Here, we show that bosutinib, an FDA-approved chemotherapeutic for treating chronic myelogenous leukemia, does not possess any antibiotic activity but ... ...

Abstract	Host-acting compounds are emerging as potential alternatives to combating antibiotic resistance. Here, we show that bosutinib, an FDA-approved chemotherapeutic for treating chronic myelogenous leukemia, does not possess any antibiotic activity but enhances macrophage responses to bacterial infection. In vitro, bosutinib stimulates murine and human macrophages to kill bacteria more effectively. In a murine wound infection with vancomycin-resistant
Language	English
Publishing date	2024-04-11
Publishing country	United States
Document type	Journal Article
ISSN	2373-8227
ISSN (online)	2373-8227
DOI	10.1021/acsinfecdis.4c00086
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Article: Accelerating stabilization of weathering steel through rust modification pre-corrosion treatment.

Hu, Qiang / Yang, Shanwu / Zhang, Xu / Da, Guangjie / Zhang, Wenhua

Heliyon

2023 Volume 10, Issue 1, Page(s) e23842

Abstract: To accelerate the formation of the protective rust layer on weathering steel, a new pre-corrosion method containing a replacement reaction was explored. This process was mixed with Cu in the pre-corrosion rust layer to imitate the enrichment of alloying ... ...

Abstract	To accelerate the formation of the protective rust layer on weathering steel, a new pre-corrosion method containing a replacement reaction was explored. This process was mixed with Cu in the pre-corrosion rust layer to imitate the enrichment of alloying elements through long-term corrosion. By using various analysis methods, the initial corrosion behavior of weathering steel and carbon steel with/without pre-corrosion treatment was studied under indoor wet-dry cycle conditions. The results showed that the pre-corrosion treatment covers the steel surface with a rust layer containing high-concentration Cu. Subsequently, the corrosion uniformity of the weathering steel was significantly improved, and the protective performance of corrosion products was enhanced due to the high concentration of Cu enrichment. This technology is expected to provide a new way to perfect the service performance of weathering steel at the initial stage of application.
Language	English
Publishing date	2023-12-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e23842
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Article ; Online: Identification of COL1A1 associated with immune infiltration in brain lower grade glioma.

Ren, Junyu / Da, Junlong / Hu, Narisu

PloS one

2022 Volume 17, Issue 7, Page(s) e0269533

Abstract: Brain low grade gliomas (LGG) often give serious clinical symptoms due to the invasion towards nervous system, affecting the life quality of patients. Collagen type I alpha 1(COL1A1) is the main component of type I collagen. Although there are many ... ...

Abstract	Brain low grade gliomas (LGG) often give serious clinical symptoms due to the invasion towards nervous system, affecting the life quality of patients. Collagen type I alpha 1(COL1A1) is the main component of type I collagen. Although there are many reports about abnormal expression of COL1A1 in various tumors, specific role and clinical significance of COL1A1 in LGG have not yet been elucidated. In this work, Tumor Immune Estimation Resource database was used for detecting the expression level of COL1A1 in cancer and normal tissues, and aimed to explore the relationship between COL1A1 and tumor immune infiltration. We applied Kaplan-Meier to analyze the role of COL1A1 in clinical prognosis. Univariate survival rate and multivariate Cox analysis were used to compare clinical characteristics and survival rate. The relativity between the expression of COL1A1 and the tumor microenvironment was evaluated using ESTIMATE algorithm. Finally, the relationship between expression level of COL1A1 and gene marker sets of immune cell infiltration was investigated via TIMER. According to TCGA, COL1A1 overexpression was correlated with overall survival (OS), progression free interval (PFI) and disease specific survival (DSS) of multiple tumors, especially in LGG. Multivariate analysis showed that COL1A1 expression was an independent prognostic factor for LGG. The expression of COL1A1 was positively correlated with the infiltration of CD4 + T and CD8 + T cells, neutrophils, macrophages and dendritic cells in LGG. In addition, there was a strong correlation between expression of COL1A1 and different immune marker sets in LGG. The results suggest that COL1A1 is related with tumor immune infiltration of LGG.
MeSH term(s)	Biomarkers, Tumor/genetics ; Brain/pathology ; Brain Neoplasms/pathology ; Glioma/pathology ; Humans ; Prognosis ; Tumor Microenvironment/genetics
Chemical Substances	Biomarkers, Tumor
Language	English
Publishing date	2022-07-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0269533
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Article ; Online: Prediction of negative refraction in Dirac semimetal metamaterial.

Da, Haixia / Song, Qi / Hu, Pengya / Ye, Huapeng

Nanotechnology

2022 Volume 33, Issue 41

Abstract: Negative refraction materials are indispensable building blocks in the optoelectric devices for their unique functionalities of controlling the light propagations, such as, superlens and transformation optics. However, material realizations of negative ... ...

Abstract	Negative refraction materials are indispensable building blocks in the optoelectric devices for their unique functionalities of controlling the light propagations, such as, superlens and transformation optics. However, material realizations of negative refraction are still limited to the conventional metals, semiconductors as well as magnetic materials. Here, we show that three dimensional Dirac semimetals have the opportunity to enable the negative refraction, which can be achieved through alternatively stacking three dimensional Dirac semimetals and the dielectric layers together. It is found that the effective perpendicular and parallel permittivities in this multilayered stack display the respective negative and positive values over a certain frequency region, which enables its negative group refractive angle and it can be controlled by the Fermi energy of Dirac semimetals. The spectra of transmittance in the multilayered structure for transverse magnetic wave also reveals an incident angle-independent transmittance dip, which originates from the zero value of the real part of the effective perpendicular permittivity. Our findings unveil the essential role of three dimensional Dirac semimetals in producing the negative group refraction responses and promise their applications in the metamaterial-based devices.
Language	English
Publishing date	2022-07-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1362365-5
ISSN	1361-6528 ; 0957-4484
ISSN (online)	1361-6528
ISSN	0957-4484
DOI	10.1088/1361-6528/ac7ded
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Article ; Online: Regulating bacterial biofilms in food and biomedicine: unraveling mechanisms and Innovating strategies.

Cheng, Jun-Hu / Du, Rong / Sun, Da-Wen

Critical reviews in food science and nutrition

2024 , Page(s) 1–17

Abstract: Bacterial biofilm has brought a lot of intractable problems in food and biomedicine areas. Conventional biofilm control mainly focuses on inactivation and removal of biofilm. However, with robust construction and enhanced resistance, the established ... ...

Abstract	Bacterial biofilm has brought a lot of intractable problems in food and biomedicine areas. Conventional biofilm control mainly focuses on inactivation and removal of biofilm. However, with robust construction and enhanced resistance, the established biofilm is extremely difficult to eradicate. According to the mechanism of biofilm development, biofilm formation can be modulated by intervening in the key factors and regulatory systems. Therefore, regulation of biofilm formation has been proposed as an alternative way for effective biofilm control. This review aims to provide insights into the regulation of biofilm formation in food and biomedicine. The underlying mechanisms for early-stage biofilm establishment are summarized based on the key factors and correlated regulatory networks. Recent developments and applications of novel regulatory strategies such as anti/pro-biofilm agents, nanomaterials, functionalized surface materials and physical strategies are also discussed. The current review indicates that these innovative methods have contributed to effective biofilm control in a smart, safe and eco-friendly way. However, standard methodology for regulating biofilm formation in practical use is still missing. As biofilm formation in real-world systems could be far more complicated, further studies and interdisciplinary collaboration are still needed for simulation and experiments in the industry and other open systems.
Language	English
Publishing date	2024-02-21
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1037504-1
ISSN	1549-7852 ; 1040-8398
ISSN (online)	1549-7852
ISSN	1040-8398
DOI	10.1080/10408398.2024.2312539
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