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  1. Article ; Online: Infectious Myelopathies.

    Anand, Pria

    Seminars in neurology

    2021  Volume 41, Issue 3, Page(s) 280–290

    Abstract: In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, ... ...

    Abstract In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, acute flaccid paralysis related to anterior horn cell involvement, spinal cord compression, chronic spastic paraparesis, and myeloradiculitis. Causative pathogens include viruses, parasites, pyogenic and atypical bacteria, and fungi. The epidemiology, clinical characteristics, diagnosis, and treatment of selected organisms will be discussed in this article.
    MeSH term(s) Central Nervous System Viral Diseases ; Humans ; Myelitis ; Myelitis, Transverse ; Neuromuscular Diseases ; Spinal Cord ; Spinal Cord Compression ; Spinal Cord Diseases
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0041-1725126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1737: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Neurologic Infections in Patients on Immunomodulatory and Immunosuppressive Therapies.

    Anand, Pria

    Continuum (Minneapolis, Minn.)

    2021  Volume 27, Issue 4, Page(s) 1066–1104

    Abstract: Purpose of review: Both broadly immunosuppressive medications and selective immunomodulatory agents that act on particular components of the immune system are increasingly used in the treatment of neurologic and non-neurologic diseases. These therapies ... ...

    Abstract Purpose of review: Both broadly immunosuppressive medications and selective immunomodulatory agents that act on particular components of the immune system are increasingly used in the treatment of neurologic and non-neurologic diseases. These therapies predispose patients to particular infections, some of which may affect the nervous system. Therefore, familiarity with the clinical and radiologic features of neurologic infections associated with specific immunomodulatory therapies is of importance for the practicing neurologist. This article reviews these neuroinfectious conditions, as well as other neurologic complications unique to transplant recipients and other patients who are immunocompromised.
    Recent findings: Diagnosis of infectious pathogens in patients who are immunocompromised may be particularly challenging because a decreased immune response can lead to atypical imaging or laboratory findings. Next-generation sequencing and other novel diagnostic modalities may improve the rate of early identification of neurologic infections in patients who are immunocompromised and ultimately ameliorate outcomes in this vulnerable population.
    Summary: A broad range of bacterial, viral, fungal, and parasitic infections of the nervous system can complicate solid organ and hematopoietic cell transplantation as well as other forms of immunocompromise. In addition to neurologic infections, such patients are at risk of neurotoxic and neuroinflammatory complications related to immunomodulatory and immunosuppressive therapies. Early recognition of infectious and noninfectious complications of immunocompromise is essential to guide appropriate treatment, which can include antimicrobial therapy and, in some cases, withdrawal of the predisposing medication with a transition to an alternative regimen.
    MeSH term(s) Communicable Diseases ; Humans ; Immunity ; Immunocompromised Host ; Immunomodulating Agents ; Immunomodulation ; Immunosuppression Therapy ; Immunosuppressive Agents/adverse effects
    Chemical Substances Immunomodulating Agents ; Immunosuppressive Agents
    Language English
    Publishing date 2021-10-08
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1538-6899
    ISSN (online) 1538-6899
    DOI 10.1212/CON.0000000000000985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Global & Community Health: The

    Anand, Pria

    Neurology

    2019  Volume 92, Issue 15, Page(s) 725–727

    MeSH term(s) Epilepsy/epidemiology ; Epilepsy/therapy ; Global Health ; Guinea ; Humans ; Medicine, African Traditional ; Neurologists/statistics & numerical data ; Public Health ; Superstitions
    Language English
    Publishing date 2019-05-31
    Publishing country United States
    Document type Journal Article ; Personal Narrative ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000007274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pandemic Neurology.

    Anand, Pria / Cervantes-Arslanian, Anna M / Feske, Steven

    Seminars in neurology

    2023  Volume 43, Issue 2, Page(s) 186

    Language English
    Publishing date 2023-06-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0043-1768978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Infectious Myelopathies

    Anand, Pria

    Seminars in Neurology

    (Myelopathy)

    2021  Volume 41, Issue 03, Page(s) 280–290

    Abstract: In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, ... ...

    Series title Myelopathy
    Abstract In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, acute flaccid paralysis related to anterior horn cell involvement, spinal cord compression, chronic spastic paraparesis, and myeloradiculitis. Causative pathogens include viruses, parasites, pyogenic and atypical bacteria, and fungi. The epidemiology, clinical characteristics, diagnosis, and treatment of selected organisms will be discussed in this article.
    Keywords myelopathy ; chronic spastic paraparesis ; myeloradiculitis
    Language English
    Publishing date 2021-05-19
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0041-1725126
    Database Thieme publisher's database

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  6. Article ; Online: Inpatient Consultations in Neurology.

    Anand, Pria / Klein, Joshua P

    Seminars in neurology

    2021  Volume 41, Issue 5, Page(s) 475–476

    MeSH term(s) Humans ; Inpatients ; Neurology ; Referral and Consultation
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0041-1735804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Challenging Cases in Neurology: Neurologic Complications of COVID-19.

    Horta, Lucas / Bakhtyari, Ava / Greige, Tatiana / Anand, Pria

    Seminars in neurology

    2022  

    Language English
    Publishing date 2022-11-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/a-1985-0460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Characteristics and evolution of cerebral aneurysms among adults living with HIV: A retrospective, longitudinal case series.

    White, Emily I / Anand, Pria / Cervantes-Arslanian, Anna M

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2023  Volume 32, Issue 6, Page(s) 107127

    Abstract: Objective: Previous research indicates an increased risk of cerebral aneurysm formation in adults living with human immunodeficiency virus (ALWH), however there are few longitudinal studies on the risk factors for and outcomes of cerebral aneurysms in ... ...

    Abstract Objective: Previous research indicates an increased risk of cerebral aneurysm formation in adults living with human immunodeficiency virus (ALWH), however there are few longitudinal studies on the risk factors for and outcomes of cerebral aneurysms in this population. We aim to describe the characteristics and evolution of cerebral aneurysms in a large cohort of ALWH.
    Materials and methods: A chart review was completed for all adults evaluated at an urban, safety-net U.S. hospital between January 1, 2000, and October 22, 2021, with history of both HIV and at least one cerebral aneurysm.
    Results: A total of 82 cerebral aneurysms were identified amongst 50 patients (52% female sex). Forty-six percent of patients with a nadir CD4 count less than 200 cells/mm
    Conclusions: Among ALWH, lower CD4 nadir, higher zenith viral load, and inconsistent ART use may contribute to aneurysm formation or growth. Further studies are needed to more thoroughly characterize the association between immunologic status and cerebral aneurysm formation.
    MeSH term(s) Humans ; Adult ; Female ; Male ; Retrospective Studies ; HIV ; Antiretroviral Therapy, Highly Active/adverse effects ; Anti-HIV Agents/therapeutic use ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/epidemiology ; CD4 Lymphocyte Count ; HIV Infections/complications ; HIV Infections/diagnosis ; HIV Infections/drug therapy
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2023.107127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Approach to Neurologic Complications in the Immunocompromised Patient.

    Vishnevetsky, Anastasia / Anand, Pria

    Seminars in neurology

    2021  Volume 41, Issue 5, Page(s) 554–571

    Abstract: Neurologic complications are common in immunocompromised patients, including those with advanced human immunodeficiency virus, transplant recipients, and patients on immunomodulatory medications. In addition to the standard differential diagnosis, ... ...

    Abstract Neurologic complications are common in immunocompromised patients, including those with advanced human immunodeficiency virus, transplant recipients, and patients on immunomodulatory medications. In addition to the standard differential diagnosis, specific pathogens and other conditions unique to the immunocompromised state should be considered in the evaluation of neurologic complaints in this patient population. A thorough understanding of these considerations is critical to the inpatient neurologist in contemporary practice, as increasing numbers of patients are exposed to immunomodulatory therapies. In this review, we provide a chief complaint-based approach to the clinical presentations and diagnosis of both infectious and noninfectious complications particular to immunocompromised patients.
    MeSH term(s) Communicable Diseases ; Humans ; Immunocompromised Host ; Transplant Recipients
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603165-1
    ISSN 1098-9021 ; 0271-8235
    ISSN (online) 1098-9021
    ISSN 0271-8235
    DOI 10.1055/s-0041-1733795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Shortcomings of Rapid Clinical Information Dissemination: Lessons From a Pandemic.

    Lau, K H Vincent / Anand, Pria

    Neurology. Clinical practice

    2021  Volume 11, Issue 3, Page(s) e337–e343

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic has led to an acceleration of clinical information dissemination to unprecedented speeds, a phenomenon only partially explained by formal efforts of the scientific community. These have ranged from the ... ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to an acceleration of clinical information dissemination to unprecedented speeds, a phenomenon only partially explained by formal efforts of the scientific community. These have ranged from the establishment of open-source platforms for review of article preprints to the elimination of journal paywalls for COVID-19-related publications. In addition, informal efforts that rely on various modern media platforms that promote, repackage, and synthesize information have played substantial adjunctive roles, many of which did not exist during the severe acute respiratory syndrome pandemic of 2003. Although these latter efforts have greatly bolstered the speed of knowledge dissemination, their unregulated nature subjects them to risk for facilitating the spread of misinformation. In our opinion, the role of modern media in influencing clinical knowledge dissemination was not adequately examined even before the pandemic and therefore remains largely unchecked. In this article, we examine the spread of information in the field of COVID-19 and neurologic disorders, develop a simple model that maps various modern media tools on to the dissemination pipeline, and critically examine its components. Through this exercise, we identify opportunities for the scientific community to regulate and safeguard the clinical knowledge dissemination process, with implications both for the pandemic and beyond.
    Language English
    Publishing date 2021-08-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000000915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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