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  1. Article: [Rezension von: Kaiser, Stefan, ...,, Die Dynamik der Unternehmenstransformation in Osteuropa]

    Schwarz, Rainer / Kayser, Stefan

    Journal of business economics : JBE Vol. 71, No. 5 , p. 600-602

    2001  Volume 71, Issue 5, Page(s) 600–602

    Author's details Rainer Schwarz
    Keywords 40#49
    Language German
    Publisher Springer
    Publishing place Berlin
    Document type Article
    ZDB-ID 201074-4 ; 2059561-X
    ISSN 1861-8928 ; 0044-2372
    ISSN (online) 1861-8928
    ISSN 0044-2372
    Database ECONomics Information System

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  2. Article ; Online: C-Reactive Protein Triggers Cell Death in Ischemic Cells.

    Sheriff, Ahmed / Kayser, Stefan / Brunner, Patrizia / Vogt, Birgit

    Frontiers in immunology

    2021  Volume 12, Page(s) 630430

    Abstract: C-reactive protein (CRP) is the best-known acute phase protein. In humans, almost every type of inflammation is accompanied by an increase of CRP concentration. Until recently, the only known physiological function of CRP was the marking of cells to ... ...

    Abstract C-reactive protein (CRP) is the best-known acute phase protein. In humans, almost every type of inflammation is accompanied by an increase of CRP concentration. Until recently, the only known physiological function of CRP was the marking of cells to initiate their phagocytosis. This triggers the classical complement pathway up to C4, which helps to eliminate pathogens and dead cells. However, vital cells with reduced energy supply are also marked, which is useful in the case of a classical external wound because an important substrate for pathogens is disposed of, but is counterproductive at internal wounds (e.g., heart attack or stroke). This mechanism negatively affects clinical outcomes since it is established that CRP levels correlate with the prognosis of these indications. Here, we summarize what we can learn from a clinical study in which CRP was adsorbed from the bloodstream by CRP-apheresis. Recently, it was shown that CRP can have a direct effect on blood pressure in rabbits. This is interesting in regard to patients with high inflammation, as they often become tachycardic and need catecholamines. These two physiological effects of CRP apparently also occur in COVID-19. Parts of the lung become ischemic due to intra-alveolar edema and hemorrhage and in parallel CRP increases dramatically, hence it is assumed that CRP is also involved in this ischemic condition. It is meanwhile considered that most of the damage in COVID-19 is caused by the immune system. The high amounts of CRP could have an additional influence on blood pressure in severe COVID-19.
    MeSH term(s) Animals ; C-Reactive Protein/immunology ; COVID-19/immunology ; Cell Death/immunology ; Cell Hypoxia/immunology ; Complement C4/immunology ; Humans ; Myocardial Infarction/immunology ; Rabbits ; SARS-CoV-2/immunology ; Stroke/immunology
    Chemical Substances Complement C4 ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2021-02-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.630430
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  3. Article ; Online: Selective C-reactive protein apheresis for Covid-19 patients suffering from organ damage.

    Kayser, Stefan / Kunze, Rudolf / Sheriff, Ahmed

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

    2020  Volume 25, Issue 2, Page(s) 251–252

    MeSH term(s) Blood Component Removal/methods ; C-Reactive Protein/adverse effects ; COVID-19/blood ; COVID-19/complications ; COVID-19/therapy ; Heart Diseases/blood ; Heart Diseases/complications ; Heart Diseases/prevention & control ; Humans ; Pulmonary Fibrosis/blood ; Pulmonary Fibrosis/complications ; Pulmonary Fibrosis/prevention & control ; SARS-CoV-2
    Chemical Substances C-Reactive Protein (9007-41-4)
    Keywords covid19
    Language English
    Publishing date 2020-06-23
    Publishing country Australia
    Document type Letter
    ZDB-ID 2119809-3
    ISSN 1744-9987 ; 1091-6660 ; 1744-9979
    ISSN (online) 1744-9987
    ISSN 1091-6660 ; 1744-9979
    DOI 10.1111/1744-9987.13532
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: A theoretical and empirical analysis of trust in dynamic production functions

    Kayser, Stefan

    Schmalenbach business review : Sbr Vol. 67, No. 2 , p. 144-170

    2015  Volume 67, Issue 2, Page(s) 144–170

    Author's details Stefan Kayser
    Keywords Dispositive Factor ; Dynamic Production Function ; Trust
    Language English
    Publisher Verl.-Gruppe Handelsblatt
    Publishing place Düsseldorf ; Frankfurt, M
    Document type Article
    ZDB-ID 2000981-1
    ISSN 1439-2917
    Database ECONomics Information System

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  5. Article: Synchronization of ear-EEG and audio streams in a portable research hearing device.

    Dasenbrock, Steffen / Blum, Sarah / Maanen, Paul / Debener, Stefan / Hohmann, Volker / Kayser, Hendrik

    Frontiers in neuroscience

    2022  Volume 16, Page(s) 904003

    Abstract: Recent advancements in neuroscientific research and miniaturized ear-electroencephalography (EEG) technologies have led to the idea of employing brain signals as additional input to hearing aid algorithms. The information acquired through EEG could ... ...

    Abstract Recent advancements in neuroscientific research and miniaturized ear-electroencephalography (EEG) technologies have led to the idea of employing brain signals as additional input to hearing aid algorithms. The information acquired through EEG could potentially be used to control the audio signal processing of the hearing aid or to monitor communication-related physiological factors. In previous work, we implemented a research platform to develop methods that utilize EEG in combination with a hearing device. The setup combines currently available mobile EEG hardware and the so-called Portable Hearing Laboratory (PHL), which can fully replicate a complete hearing aid. Audio and EEG data are synchronized using the Lab Streaming Layer (LSL) framework. In this study, we evaluated the setup in three scenarios focusing particularly on the alignment of audio and EEG data. In Scenario I, we measured the latency between software event markers and actual audio playback of the PHL. In Scenario II, we measured the latency between an analog input signal and the sampled data stream of the EEG system. In Scenario III, we measured the latency in the whole setup as it would be used in a real EEG experiment. The results of Scenario I showed a jitter (standard deviation of trial latencies) of below 0.1 ms. The jitter in Scenarios II and III was around 3 ms in both cases. The results suggest that the increased jitter compared to Scenario I can be attributed to the EEG system. Overall, the findings show that the measurement setup can time-accurately present acoustic stimuli while generating LSL data streams over multiple hours of playback. Further, the setup can capture the audio and EEG LSL streams with sufficient temporal accuracy to extract event-related potentials from EEG signals. We conclude that our setup is suitable for studying closed-loop EEG & audio applications for future hearing aids.
    Language English
    Publishing date 2022-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2022.904003
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  8. Article ; Online: A Step towards Neuro-Steered Hearing Aids

    Dasenbrock Steffen / Blum Sarah / Debener Stefan / Hohmann Volker / Kayser Hendrik

    Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 855-

    Integrated Portable Setup for Time- Synchronized Acoustic Stimuli Presentation and EEG Recording

    2021  Volume 858

    Abstract: Aiming to provide a portable research platform to develop algorithms for neuro-steered hearing aids, a joint hearing aid - EEG measurement setup was implemented in this work. The setup combines the miniaturized electroencephalography sensor technology ... ...

    Abstract Aiming to provide a portable research platform to develop algorithms for neuro-steered hearing aids, a joint hearing aid - EEG measurement setup was implemented in this work. The setup combines the miniaturized electroencephalography sensor technology cEEGrid with a portable hearing aid research platform - the Portable Hearing Laboratory. The different components of the system are connected wirelessly, using the lab streaming layer framework for synchronization of audio and EEG data streams. Our setup was shown to be suitable for simultaneous recording of audio and EEG signals used in a pilot study (n=5) to perform an auditory Oddball experiment. The analysis showed that the setup can reliably capture typical event-related potential responses. Furthermore, linear discriminant analysis was successfully applied for single-trial classification of P300 responses. The study showed that time-synchronized audio and EEG data acquisition is possible with the Portable Hearing Laboratory research platform.
    Keywords portable hearing laboratory ; open master hearing aid ; openmha ; hearing aids ; ceegrid ; around-theear eeg ; eeg ; portable setup ; auditory oddball ; Medicine ; R
    Subject code 390
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Selective Apheresis of C-Reactive Protein for Treatment of Indications with Elevated CRP Concentrations.

    Kayser, Stefan / Brunner, Patrizia / Althaus, Katharina / Dorst, Johannes / Sheriff, Ahmed

    Journal of clinical medicine

    2020  Volume 9, Issue 9

    Abstract: Almost every kind of inflammation in the human body is accompanied by rising C-reactive protein (CRP) concentrations. This can include bacterial and viral infection, chronic inflammation and so-called sterile inflammation triggered by (internal) acute ... ...

    Abstract Almost every kind of inflammation in the human body is accompanied by rising C-reactive protein (CRP) concentrations. This can include bacterial and viral infection, chronic inflammation and so-called sterile inflammation triggered by (internal) acute tissue injury. CRP is part of the ancient humoral immune response and secreted into the circulation by the liver upon respective stimuli. Its main immunological functions are the opsonization of biological particles (bacteria and dead or dying cells) for their clearance by macrophages and the activation of the classical complement pathway. This not only helps to eliminate pathogens and dead cells, which is very useful in any case, but unfortunately also to remove only slightly damaged or inactive human cells that may potentially regenerate with more CRP-free time. CRP action severely aggravates the extent of tissue damage during the acute phase response after an acute injury and therefore negatively affects clinical outcome. CRP is therefore a promising therapeutic target to rescue energy-deprived tissue either caused by ischemic injury (e.g., myocardial infarction and stroke) or by an overcompensating immune reaction occurring in acute inflammation (e.g., pancreatitis) or systemic inflammatory response syndrome (SIRS; e.g., after transplantation or surgery). Selective CRP apheresis can remove circulating CRP safely and efficiently. We explain the pathophysiological reasoning behind therapeutic CRP apheresis and summarize the broad span of indications in which its application could be beneficial with a focus on ischemic stroke as well as the results of this therapeutic approach after myocardial infarction.
    Keywords covid19
    Language English
    Publishing date 2020-09-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm9092947
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  10. Article ; Online: Selective C‐reactive protein apheresis for Covid‐19 patients suffering from organ damage

    Kayser, Stefan / Kunze, Rudolf / Sheriff, Ahmed

    Therapeutic Apheresis and Dialysis ; ISSN 1744-9979 1744-9987

    2020  

    Keywords Nephrology ; Hematology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/1744-9987.13532
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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