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  1. Article: Blood count, endocrine, immunologic, renal, and hepatic markers in a case-control animal study of induced periodontitis in female rodents.

    Estarreja, João / Pimenta, Ana Clara / Botelho, João / Vilares, Arminda Maria / Mendes, José João / Rocha, João / Pinto, Rui / Mateus, Vanessa / Machado, Vanessa

    Frontiers in physiology

    2024  Volume 15, Page(s) 1327399

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2024.1327399
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  2. Article ; Online: Trypanosoma cruzi

    Puerta, Concepción J / Cuellar, Adriana / Lasso, Paola / Mateus, Jose / Gonzalez, John M

    Frontiers in cellular and infection microbiology

    2023  Volume 12, Page(s) 1075717

    Abstract: Trypanosoma ... ...

    Abstract Trypanosoma cruzi
    MeSH term(s) Animals ; Humans ; Mice ; CD8-Positive T-Lymphocytes/immunology ; Chagas Cardiomyopathy/immunology ; Chagas Cardiomyopathy/parasitology ; Epitopes, T-Lymphocyte ; Persistent Infection/immunology ; Persistent Infection/parasitology ; Trypanosoma cruzi/immunology
    Chemical Substances Epitopes, T-Lymphocyte
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.1075717
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  3. Article: How Do Escape Distance Behavior of Broiler Chickens Change in Response to a Mobile Robot Moving at Two Different Speeds?

    da Rocha Balthazar, Glauber / Silveira, Robson Mateus Freitas / da Silva, Iran José Oliveira

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 7

    Abstract: In poultry farming, robots are considered by birds as intruder elements to their environment, because animals escape due to their movement. Their escape is measured using the escape distance (ED) technique. This study analyzes the behavior of animals in ... ...

    Abstract In poultry farming, robots are considered by birds as intruder elements to their environment, because animals escape due to their movement. Their escape is measured using the escape distance (ED) technique. This study analyzes the behavior of animals in relation to their ED through the use of a robot with two speeds: 12 rpm and 26 rpm. The objective is to understand whether the speeds cause variations in ED and their implications for animal stress. A broiler breeding cycle was analyzed (six weeks) through the introduction of the robot weekly. ED analyses were carried out on static images generated from footage of the robot running. The results indicate higher escape distance rates (
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14071014
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  4. Article ; Online: Emerging threats: global distribution and diversity of carbapenem resistance genes in Kluyvera intermedia.

    Monte, Daniel F M / Lemos, Mateus Lacerda Pereira / de Oliveira, Celso José Bruno

    The Lancet. Microbe

    2023  Volume 5, Issue 4, Page(s) e310–e311

    MeSH term(s) Kluyvera/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Carbapenems/pharmacology ; Carbapenems/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Carbapenems
    Language English
    Publishing date 2023-12-20
    Publishing country England
    Document type Journal Article
    ISSN 2666-5247
    ISSN (online) 2666-5247
    DOI 10.1016/S2666-5247(23)00390-7
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  5. Article ; Online: A participação popular nas agências reguladoras da Bahia

    Mateus Wildberger / José Gileá

    Research, Society and Development, Vol 9, Iss

    2020  Volume 8

    Abstract: Este artigo trata da Agência Estadual de Regulação de Serviços Públicos de Energia, Transportes e Comunicações da Bahia (AGERBA) e da Agência Reguladora de Saneamento Básico do Estado da Bahia (AGERSA), únicas agências reguladoras do Estado da Bahia. O ... ...

    Abstract Este artigo trata da Agência Estadual de Regulação de Serviços Públicos de Energia, Transportes e Comunicações da Bahia (AGERBA) e da Agência Reguladora de Saneamento Básico do Estado da Bahia (AGERSA), únicas agências reguladoras do Estado da Bahia. O objetivo proposto foi analisar a participação popular nessas agências mediante a adoção do modelo deliberativo como instrumento de legitimação dos atos regulatórios. A pesquisa foi realizada sob a vertente metodológica jurídico-dogmática, analisando-se a legislação vigente, assim como os conceitos jurídicos atinentes à temática. Conclui-se que o modelo deliberativo foi adotado pelas agências, mas, em diferentes níveis, fazendo-se necessária a revisão legislativa para aprimorar a participação popular.
    Keywords AGERBA ; AGERSA ; Insulamento burocrático ; Modelo deliberativo ; Special aspects of education ; LC8-6691 ; Science (General) ; Q1-390 ; Social Sciences ; H
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Post-New Public Management, governança e controle externo

    Mateus Wildberger / José Gileá

    Research, Society and Development, Vol 9, Iss

    um diálogo necessário

    2020  Volume 8

    Abstract: Este artigo tem por objetivo analisar os pressupostos teóricos do P-NPM e a governança na sua perspectiva dinâmica, assim como a atuação dos órgãos de controle externo sob essa teoria gerencial que se contrapõe ao modelo weberiano. A análise trata das ... ...

    Abstract Este artigo tem por objetivo analisar os pressupostos teóricos do P-NPM e a governança na sua perspectiva dinâmica, assim como a atuação dos órgãos de controle externo sob essa teoria gerencial que se contrapõe ao modelo weberiano. A análise trata das mudanças propostas pelo post-new public management, sob a influência direta da governança e a necessidade dos órgãos de controle externo da Administração Pública dialogarem com essa nova prática administrativa. A metodologia utilizada foi a descritiva quanto ao objeto de estudo, valendo-se da abordagem hipotético-dedutiva. As conclusões do trabalho indicam que os órgãos de controle externo têm uma atuação focada em aspectos formais, fincados no legalismo estéril, sendo necessária a reformulação dessa atuação passando a ter o foco nos resultados sociais obtidos, favorecendo o surgimento de novas formas de solução dos problemas postos, além de novos arranjos institucionais.
    Keywords Post-new public management ; Governança ; Controle externo ; Special aspects of education ; LC8-6691 ; Science (General) ; Q1-390 ; Social Sciences ; H
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Patient preferences and cost-benefit of hypertension and hyperlipidemia collaborative management model between pharmacies and primary care in Portugal: A discrete choice experiment alongside a trial (USFarmácia®).

    Costa, Suzete / Guerreiro, José / Teixeira, Inês / Helling, Dennis K / Mateus, Céu / Pereira, João

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0292308

    Abstract: Background: Little is known about patient preferences and the value of pharmacy-collaborative disease management with primary care using technology-driven interprofessional communication under real-world conditions. Discrete Choice Experiments (DCEs) ... ...

    Abstract Background: Little is known about patient preferences and the value of pharmacy-collaborative disease management with primary care using technology-driven interprofessional communication under real-world conditions. Discrete Choice Experiments (DCEs) are useful for quantifying preferences for non-market services.
    Objectives: 1) To explore variation in patient preferences and estimate willingness-to-accept annual cost to the National Health Service (NHS) for attributes of a collaborative intervention trial between pharmacies and primary care using a trial exit DCE interview; 2) to incorporate a DCE into an economic evaluation using cost-benefit analysis (CBA).
    Methods: We performed a DCE telephone interview with a sample of hypertension and hyperlipidemia trial patients 12 months after trial onset. We used five attributes (levels): waiting time to get urgent/not urgent medical appointment (7 days/45 days; 48 hrs./30 days; same day/15 days), model of pharmacy intervention (5-min. counter basic check; 15-min. office every 3 months for BP and medication review of selected medicines; 30-min. office every 6 months for comprehensive measurements and medication review of all medicines), integration with primary care (weak; partial; full), chance of having a stroke in 5 years (same; slightly lower; much lower), and annual cost to the NHS (0€; 30€; 51€; 76€). We used an experimental orthogonal fractional factorial design. Data were analyzed using conditional logit. We subtracted the estimated annual incremental trial costs from the mean WTA (Net Benefit) for CBA.
    Results: A total of 122 patients completed the survey. Waiting time to get medical appointment-on the same day (urgent) and within 15 days (non-urgent)-was the most important attribute, followed by 30-minute pharmacy intervention in private office every 6 months for point-of-care measurements and medication review of all medicines, and full integration with primary care. The cost attribute was not significant. Intervention patients were willing to accept the NHS annual cost of €877 for their preferred scenario. The annual net benefit per patient is €788.20 and represents the monetary value of patients' welfare surplus for this model.
    Conclusions: This study is the first conducted in Portugal alongside a pharmacy collaborative trial, incorporating DCE into CBA. The findings can be used to guide the design of pharmacy collaborative interventions with primary care with the potential for reimbursement for uncontrolled or at-risk chronic disease patients informed by patient preferences. Future DCE studies conducted in community pharmacy may provide additional contributions.
    Trial registration: Current Controlled Trials (ISRCTN): ISRCTN13410498, retrospectively registered on 12 December 2018.
    MeSH term(s) Humans ; Cost-Benefit Analysis ; Hyperlipidemias/therapy ; Hypertension/therapy ; Patient Preference ; Pharmacies ; Portugal ; Primary Health Care ; State Medicine
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0292308
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  8. Article ; Online: Comparative genomics reveals probable adaptations for xylose use in Thermoanaerobacterium saccharolyticum.

    Fiamenghi, Mateus Bernabe / Prodonoff, Juliana Silveira / Borelli, Guilherme / Carazzolle, Marcelo Falsarella / Pereira, Gonçalo Amarante Guimaraes / José, Juliana

    Extremophiles : life under extreme conditions

    2024  Volume 28, Issue 1, Page(s) 9

    Abstract: Second-generation ethanol, a promising biofuel for reducing greenhouse gas emissions, faces challenges due to the inefficient metabolism of xylose, a pentose sugar. Overcoming this hurdle requires exploration of genes, pathways, and organisms capable of ... ...

    Abstract Second-generation ethanol, a promising biofuel for reducing greenhouse gas emissions, faces challenges due to the inefficient metabolism of xylose, a pentose sugar. Overcoming this hurdle requires exploration of genes, pathways, and organisms capable of fermenting xylose. Thermoanaerobacterium saccharolyticum is an organism capable of naturally fermenting compounds of industrial interest, such as xylose, and understanding evolutionary adaptations may help to bring novel genes and information that can be used for industrial yeast, increasing production of current bio-platforms. This study presents a deep evolutionary study of members of the firmicutes clade, focusing on adaptations in Thermoanaerobacterium saccharolyticum that may be related to overall fermentation metabolism, especially for xylose fermentation. One highlight is the finding of positive selection on a xylose-binding protein of the xylFGH operon, close to the annotated sugar binding site, with this protein already being found to be expressed in xylose fermenting conditions in a previous study. Results from this study can serve as basis for searching for candidate genes to use in industrial strains or to improve Thermoanaerobacterium saccharolyticum as a new microbial cell factory, which may help to solve current problems found in the biofuels' industry.
    MeSH term(s) Xylose ; Thermoanaerobacterium/genetics ; Genomics ; Firmicutes ; Biofuels
    Chemical Substances Xylose (A1TA934AKO) ; Biofuels
    Language English
    Publishing date 2024-01-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1481278-2
    ISSN 1433-4909 ; 1431-0651
    ISSN (online) 1433-4909
    ISSN 1431-0651
    DOI 10.1007/s00792-023-01327-x
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  9. Article ; Online: Spatial modeling via geostatistics of the bed in a compost barn system: thermal performance assessments.

    Guesine, Giovane Debs / Silveira, Robson Mateus Freitas / da Silva, Iran José Oliveira

    International journal of biometeorology

    2023  Volume 67, Issue 11, Page(s) 1775–1788

    Abstract: For all the benefits of a compost barn system to be achieved, the management, especially with the bedding, must be done correctly. One should consider the requirements regarding the revolving of the material, use of good quality organic matter, suitable ... ...

    Abstract For all the benefits of a compost barn system to be achieved, the management, especially with the bedding, must be done correctly. One should consider the requirements regarding the revolving of the material, use of good quality organic matter, suitable ventilation, and an ideal animal stocking rate, so that the composting occurs efficiently. Given this, this work aimed to evaluate the spatial variability of thermal characteristics of rice straw bedding, using values of temperature (surface and internal) and humidity. The temperature and moisture values of the litter were recorded at intervals during the morning shift, from 6:00 am to 7:00 am and from 8:00 am to 9:00 am, and during the afternoon shift, from 3:00 pm to 4:00 pm and from 5:00 pm to 6:00 pm, considering the management of the turn-over, that is, before and after the movement of the litter. Litter variables were collected at points distributed on a 39-point grid. There were no differences between litter surface temperatures before and after turning over in the morning shift, but in the afternoon shift, the surface temperature was lower (P < 0.05) before, when compared to after turning. The internal temperature and litter moisture were higher (P < 0.05) before revolving in both shifts. Spatial dependence was verified (IDE) for the variables studied. Based on the geostatistical analysis, it is concluded that the IDE was rated as strong for surface and internal temperatures, which demonstrates heterogeneity among the points evaluated and a large spatial variability regarding bed temperatures. In the case of litter moisture, the greatest variability occurred in the morning period. The litter surface temperature values did not exceed the ambient air temperature values.
    Language English
    Publishing date 2023-08-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280324-0
    ISSN 1432-1254 ; 0020-7128
    ISSN (online) 1432-1254
    ISSN 0020-7128
    DOI 10.1007/s00484-023-02538-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Integrated Ca, Mg, Cu, and Zn supply upregulates leaf anatomy and metabolic adjustments in Eucalyptus seedlings.

    Florentino, Antonio Leite / Carvalho, Marcia Eugenia Amaral / Mateus, Nikolas de Souza / Ferraz, Alexandre de Vicente / Rossi, Monica Lanzoni / Gaziola, Salete Aparecida / Azevedo, Ricardo Antunes / Linhares, Francisco Scaglia / Lavres, José / Gonçalves, José Leonardo de Moraes

    Plant physiology and biochemistry : PPB

    2024  Volume 208, Page(s) 108446

    Abstract: Adaptive responses to abiotic stresses such as soil acidity in Eucalyptus-the most widely planted broad-leaf forest genus globally-are poorly understood. This is particularly evident in physiological and anatomical disorders that inhibit plant ... ...

    Abstract Adaptive responses to abiotic stresses such as soil acidity in Eucalyptus-the most widely planted broad-leaf forest genus globally-are poorly understood. This is particularly evident in physiological and anatomical disorders that inhibit plant development and wood quality. We aimed to explore how the supply of Ca and Mg through liming (lime), combined with Cu and Zn fertilization (CZF), influences physiological and anatomical responses during Eucalyptus grandis seedlings growth in tropical acid soil. Therefore, related parameters of leaf area and leaf anatomy, stomatal size, leaf gas exchange, antioxidant system, nutrient partitioning, and biomass allocation responses were monitored. Liming alone in Eucalyptus increased specific leaf area, stomatal density on the abaxial leaf surface, and Ca and Mg content. Also, Eucalyptus exposed only to CZF increased Cu and Zn content. Lime and CZF increased leaf blade and adaxial epidermal thickness, and improved the structural organization of the spongy mesophyll, promoting increased net CO
    MeSH term(s) Seedlings/metabolism ; Eucalyptus/metabolism ; Antioxidants/metabolism ; Plant Leaves/metabolism ; Photosynthesis/physiology ; Soil ; Zinc/metabolism ; Oxides ; Calcium Compounds
    Chemical Substances lime (C7X2M0VVNH) ; Antioxidants ; Soil ; Zinc (J41CSQ7QDS) ; Oxides ; Calcium Compounds
    Language English
    Publishing date 2024-02-23
    Publishing country France
    Document type Journal Article
    ZDB-ID 742978-2
    ISSN 1873-2690 ; 0981-9428
    ISSN (online) 1873-2690
    ISSN 0981-9428
    DOI 10.1016/j.plaphy.2024.108446
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    In stock of ZB MED Bonn / Germany

    Z 2696: Show issues
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