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Article: [SHENG Zu-Jia].

Sheng, Zu-Jia

Yi chuan = Hereditas

2008 Volume 30, Issue 11, Page(s) 1383–1384

MeSH term(s)	China ; Genetics/history ; History, 20th Century
Language	Chinese
Publishing date	2008-10-29
Publishing country	China
Document type	Biography ; Historical Article ; Journal Article ; Portrait
ISSN	0253-9772
ISSN	0253-9772
DOI	10.3724/sp.j.1005.2008.01383
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Study of the analgesic activities, chronic toxicity and addictive potential of Jia-Yuan-Qing pill in rats.

Tian, Y E / Teng, Li-Rong / Wang, Zhen-Zuo / Zhao, Min / Meng, Qing-Fan / Lu, Jia-Hui / Tian, Jian-Ming / Zhang, Wei-Wei / Zheng, Xiaoyi / Wang, D I / Teng, LE-Sheng

Experimental and therapeutic medicine

2015 Volume 9, Issue 6, Page(s) 2349–2355

Abstract: Jia-Yuan-Qing pill (JYQP) composed of ...

Abstract	Jia-Yuan-Qing pill (JYQP) composed of
Language	English
Publishing date	2015-04-15
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2015.2426
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Studies on the analgesic activities of Jia-Yuan-Qing pill and its safety evaluation in mice.

Tian, Ye / Teng, Li-rong / Song, Jing-jing / Meng, Qing-fan / Lu, Jia-hui / Zhang, Wei-wei / Wei, Kang / Wang, Ning / Wang, Di / Teng, Le-sheng

Protoplasma

2014 Volume 251, Issue 5, Page(s) 1245–1253

Abstract: ... Paniculati have been reported in recent years. A new formula named Jia-Yuan-Qing pill (JYQP) is ...

Abstract	The analgesic activity of Porcellio laevis Latreille, Rhizoma Corydalis, and Radix Cynanchi Paniculati have been reported in recent years. A new formula named Jia-Yuan-Qing pill (JYQP) is therefore created by combining the three herbs at 9:7:7 ratio according to traditional Chinese theories. The present study aims to evaluate the effect of JYQP as a novel painkiller in various models. Acute toxicity test was applied to evaluate the safety of JYQP. Acetic-acid-induced writhing, hot plate test, formalin test, and naloxone-pretreated writhing test were employed to elaborate the analgesic activity of JYQP and its possible mechanism. A bone cancer pain mouse model was performed to further assess the effect of JYQP in relieving cancer pain. Test on naloxone-precipitated withdrawal symptoms was conduct to examine the physical dependence of mice on JYQP. Data revealed that JYQP reduced writhing and stretching induced by acetic acid; however, this effect could not be blocked by naloxone. JYQP specifically suppressed the phase II reaction time in formalin-treated mice; meanwhile, no analgesic effect of JYQP in hot plate test was observed, indicating that JYQP exerts analgesic activity against inflammatory pain rather than neurogenic pain. Furthermore, JYQP could successfully relieve bone cancer pain in mice. No physical dependence could be observed upon long-term administration in mice. Collectively, our present results provide experimental evidence in supporting clinical use of JYQP as an effective and safe agent for pain treatment.
MeSH term(s)	Analgesics/adverse effects ; Analgesics/pharmacology ; Animals ; Bone Neoplasms/pathology ; Corydalis/metabolism ; Cynanchum/metabolism ; Female ; Inflammation/pathology ; Isopoda/metabolism ; Male ; Medicine, Chinese Traditional/adverse effects ; Mice ; Mice, Inbred C57BL ; Naloxone/pharmacology ; Narcotic Antagonists/pharmacology ; Pain/drug therapy ; Phytotherapy ; Plant Extracts/adverse effects ; Plant Extracts/pharmacology
Chemical Substances	Analgesics ; Narcotic Antagonists ; Plant Extracts ; Naloxone (36B82AMQ7N)
Language	English
Publishing date	2014-03-28
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	123809-7
ISSN	1615-6102 ; 0033-183X
ISSN (online)	1615-6102
ISSN	0033-183X
DOI	10.1007/s00709-014-0637-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Immediate and persistent antidepressant-like effects of Chaihu-jia-Longgu-Muli-tang are associated with instantly up-regulated BDNF in the hippocampus of mice.

Wang, Xing / Chen, Jie / Zhang, Hailou / Huang, Zhiheng / Zou, Zhilu / Chen, Yin / Sheng, Lei / Xue, Wenda / Tang, Juanjuan / Wu, Haoxin / Liu, Hongquan / Chen, Gang

Bioscience reports

2019 Volume 39, Issue 1

Abstract: ... to evaluate the immediate and persistent antidepressant-like action of a classic herbal medicine Chaihu-jia ... dose of CLM. The results support that Chaihu-jia-Longgu-Muli decoction was capable to immediately and ...

Abstract	Conventional antidepressants have a disadvantage in delayed onset of efficacy. Here, we aimed to evaluate the immediate and persistent antidepressant-like action of a classic herbal medicine Chaihu-jia-Longgu-Muli decoction (CLM) as well as the action of CLM on hippocampal brain-derived neurotrophic factor (BDNF) over time. CLM consists of Xiaochaihu decoction (XchD), Longgu-Muli (LM) and several other herbs. The contribution of constituent herbal formula XchD and other parts of CLM was also assessed. Following a single dose of CLM, tail suspension test (TST), forced swim test (FST), and novelty-suppressed feeding test (NSF) were performed. The antidepressant activity of XchD, its interaction with LM or remaining parts of CLM was also examined after a single administration. BDNF expression in the hippocampus was examined at 30 min and 24 hr post a single CLM. A single administration of half of clinical dose of CLM elicited antidepressant effects at TST 30 min post administration, and lasted for 72 hr. Furthermore, CLM also reduced the latency to eat in NSF test. A single proportional dose of XchD induced antidepressant effects at 30 min and lasted for 48 hr, whereas the effect lasted for 72 hr when combined with either LM or the remaining parts of CLM. BDNF expression increased at 30 min and persisted at least for 24 hr after a single dose of CLM. The results support that Chaihu-jia-Longgu-Muli decoction was capable to immediately and enduringly elicit antidepressant activity via enhancement of hippocampal BDNF expression, in which the constituent Xiaochaihu decoction played the primary role.
MeSH term(s)	Animals ; Antidepressive Agents/pharmacology ; Brain-Derived Neurotrophic Factor/agonists ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; Depression/drug therapy ; Depression/genetics ; Depression/metabolism ; Depression/physiopathology ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Exploratory Behavior/drug effects ; Exploratory Behavior/physiology ; Hindlimb Suspension ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Locomotion/drug effects ; Locomotion/physiology ; Male ; Medicine, Chinese Traditional ; Mice ; Mice, Inbred BALB C ; Swimming ; Up-Regulation/drug effects
Chemical Substances	Antidepressive Agents ; Bdnf protein, mouse ; Brain-Derived Neurotrophic Factor ; Drugs, Chinese Herbal
Language	English
Publishing date	2019-01-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	764946-0
ISSN	1573-4935 ; 0144-8463
ISSN (online)	1573-4935
ISSN	0144-8463
DOI	10.1042/BSR20181539
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Zs.A 1676: Show issues

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Article: Studies on the analgesic activities of Jia-Yuan-Qing pill and its safety evaluation in mice

Tian, Ye / Teng, Li-rong / Song, Jing-jing / Meng, Qing-fan / Lu, Jia-hui / Zhang, Wei-wei / Wei, Kang / Wang, Ning / Wang, Di / Teng, Le-sheng

Protoplasma. 2014 Sept., v. 251, no. 5

2014

Abstract: ... Paniculati have been reported in recent years. A new formula named Jia-Yuan-Qing pill (JYQP) is ...

Abstract	The analgesic activity of Porcellio laevis Latreille, Rhizoma Corydalis, and Radix Cynanchi Paniculati have been reported in recent years. A new formula named Jia-Yuan-Qing pill (JYQP) is therefore created by combining the three herbs at 9:7:7 ratio according to traditional Chinese theories. The present study aims to evaluate the effect of JYQP as a novel painkiller in various models. Acute toxicity test was applied to evaluate the safety of JYQP. Acetic-acid-induced writhing, hot plate test, formalin test, and naloxone-pretreated writhing test were employed to elaborate the analgesic activity of JYQP and its possible mechanism. A bone cancer pain mouse model was performed to further assess the effect of JYQP in relieving cancer pain. Test on naloxone-precipitated withdrawal symptoms was conduct to examine the physical dependence of mice on JYQP. Data revealed that JYQP reduced writhing and stretching induced by acetic acid; however, this effect could not be blocked by naloxone. JYQP specifically suppressed the phase II reaction time in formalin-treated mice; meanwhile, no analgesic effect of JYQP in hot plate test was observed, indicating that JYQP exerts analgesic activity against inflammatory pain rather than neurogenic pain. Furthermore, JYQP could successfully relieve bone cancer pain in mice. No physical dependence could be observed upon long-term administration in mice. Collectively, our present results provide experimental evidence in supporting clinical use of JYQP as an effective and safe agent for pain treatment.
Keywords	Corydalis ; Porcellio ; acetic acid ; acute toxicity ; analgesic effect ; analgesics ; animal models ; formalin ; herbs ; mice ; naloxone ; pain ; toxicity testing
Language	English
Dates of publication	2014-09
Size	p. 1245-1253.
Publishing place	Springer-Verlag
Document type	Article
ZDB-ID	123809-7
ISSN	1615-6102 ; 0033-183X
ISSN (online)	1615-6102
ISSN	0033-183X
DOI	10.1007/s00709-014-0637-9
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: In Vitro and In Vivo Effects of Jia-Wei-Xiao-Yao-San in Human Breast Cancer MCF-7 Cells Treated With Tamoxifen.

Chen, Jiun-Liang / Chang, Chun-Ju / Wang, Jir-You / Wen, Che-Sheng / Tseng, Ling-Ming / Chang, Wen-Chi / Noomhorm, Nattanant / Liu, Hui-Ju / Chen, Wei-Shone / Chiu, Jen-Hwey / Shyr, Yi-Ming

Integrative cancer therapies

2014 Volume 13, Issue 3, Page(s) 226–239

Abstract: Introduction: There is epidemiological evidence that Jia-Wei-Xiao-Yao-San (JWXYS) is the most ...

Abstract	Introduction: There is epidemiological evidence that Jia-Wei-Xiao-Yao-San (JWXYS) is the most common Chinese medicine decoction coprescribed with tamoxifen (Tam) when breast cancer is treated by hormonal therapy. However, whether there is interaction between JWXYS and Tam remains to be clarified. The aim of this study was to investigate the in vitro and in vivo effects of JWXYS on human breast cancer MCF-7 cells treated with Tam. Methods: In vitro cultured MCF-7 cells were cotreated with JWXYS and Tam. This was followed by MTT ([4,5-cimethylthiazol-2-yl]- 2,5-diphenyl tetrazolium bromide) assays and cell cycle analysis to assess cell proliferation; Western blot analysis was used to analyze the expression of various proteins involved in growth-related signal pathways. In addition, immunohistochemistry was used to detect autophagy among the cancer cells. In vivo analysis used female athymic nude mice implanted with MCF-7 cells; these mice were randomly assigned to 6 groups. All mice were killed humanely after 21 days of treatment; body weight, tumor volume, and tumor weight were then measured. Results: JWXYS was not cytotoxic to MCF-7 cells, based on the fact that there were no statistically significant changes between the JWXYS + Tam groups and the Tam-alone group in cell numbers, cell cycle progression, and cell proliferation signals, the latter including the expression levels of AKT, ERK, P38, p27(Kip1), and light chain (LC3)-I, II. Furthermore, using the MCF-7 xenograft mouse model, there were no significant changes between the JWXYS (1.3-3.9 gm/kg) + Tam groups and the Tam-alone group in terms of tumor weight and the protein expression levels of AKT, ERK, P38, and p27 (Kip1). However, there was a significant decrease in LC3-II protein expression with the low-dose JWXYS + Tam group but not with the middle- or high-dose JWXYS + Tam groups compared with the Tam-alone group. Conclusion: Based on in vitro studies and in vivo functional studies, there is no obvious interaction between JWXYS and Tam. However, the presence of interference at the molecular level in relation to LC3-II expression provides important information and may affect treatment strategies when physicians have patients with estrogen receptor-α(+) or progesterone receptor(+) breast cancers.
MeSH term(s)	Animals ; Antineoplastic Agents, Hormonal/administration & dosage ; Antineoplastic Agents, Hormonal/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cell Cycle/drug effects ; Cell Proliferation/drug effects ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/pharmacology ; Female ; Herb-Drug Interactions ; Humans ; MCF-7 Cells ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Signal Transduction/drug effects ; Tamoxifen/administration & dosage ; Tamoxifen/pharmacology ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Chemical Substances	Antineoplastic Agents, Hormonal ; Drugs, Chinese Herbal ; kamisyoyo san ; Tamoxifen (094ZI81Y45)
Language	English
Publishing date	2014-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2182320-0
ISSN	1552-695X ; 1534-7354
ISSN (online)	1552-695X
ISSN	1534-7354
DOI	10.1177/1534735414520970
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Jia zhuang xian wai ke

Sun, Sheng

1979

Title translation	Thyroid surgery.
Author's details	Sun Sheng, Gao Quanxu, Ma Binliang bian zhu
MeSH term(s)	Thyroid Diseases ; Thyroidectomy
Language	Chinese
Size	4, 225 p. :, ill.
Edition	Di 1 ban.
Publisher	Nei Menggu ren min chu ban she
Publishing place	Huhehaote
Document type	Book
Database	Catalogue of the US National Library of Medicine (NLM)

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Article: [Innovation and basic frame conception of modern acupuncture and moxibustion discipline theory system].

Wang, Rui-Qing / Jia, Chun-Sheng

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2023 Volume 42, Issue 10, Page(s) 1170–1176

Abstract: Through reviewing the construction status of the basic theory of acupuncture and moxibustion discipline from the ancient to modern eras, it is believed that the structure of acupuncture and moxibustion discipline has been formed, but nowadays, the ... ...

Abstract	Through reviewing the construction status of the basic theory of acupuncture and moxibustion discipline from the ancient to modern eras, it is believed that the structure of acupuncture and moxibustion discipline has been formed, but nowadays, the theoretical system of acupuncture and moxibustion is still on the framework of classical meridian theory, and the treatment with acupuncture and moxibustion is in reference with the mode of syndrome/pattern difference of Chinese herbal medicines. Parts of these remain ambiguity. It is proposed that the innovation of acupuncture and moxibustion discipline should focus on anatomical physiology, psychology and other multi-disciplines; and the basic framework should compose of the theoretic systems of three major disciplines, i.e.
MeSH term(s)	Moxibustion ; Acupuncture Therapy ; Acupuncture ; Meridians ; Acupuncture Points
Language	Chinese
Publishing date	2023-05-19
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	0255-2930
ISSN	0255-2930
DOI	10.13703/j.0255-2930.20211230-k0002
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Diversity of Yintiaoling Nature Reserve, China (Table of contents).

Zhang, Zhi-Sheng / Zhang, Jia-Yong

Zootaxa

2023 Volume 5257, Issue 1, Page(s) 3–4

Language	English
Publishing date	2023-03-24
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5257.1.2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Dietary fiber intake and its association with diabetic kidney disease in American adults with diabetes: A cross-sectional study.

Jia, Xin-Hua / Wang, Sheng-Yan / Sun, Ai-Qin

World journal of diabetes

2024 Volume 15, Issue 3, Page(s) 475–487

Abstract: Background: Dietary fiber (DF) intake may have a protective effect against type 2 diabetes (T2D); however, its relationship with diabetic kidney disease (DKD) remains unclear.: Aim: To investigate the potential association between DF intake and the ... ...

Abstract	Background: Dietary fiber (DF) intake may have a protective effect against type 2 diabetes (T2D); however, its relationship with diabetic kidney disease (DKD) remains unclear. Aim: To investigate the potential association between DF intake and the prevalence of DKD in individuals diagnosed with T2D. Methods: This cross-sectional study used data from the National Health and Nutrition Examination Survey collected between 2005 and 2018. DF intake was assessed through 24-h dietary recall interviews, and DKD diagnosis in individuals with T2D was based on predefined criteria, including albuminuria, impaired glomerular filtration rate, or a combination of both. Logistic regression analysis was used to assess the association between DF intake and DKD, and comprehensive subgroup and sensitivity analyses were performed. Results: Among the 6032 participants, 38.4% had DKD. With lower DF intake-T1 (≤ 6.4 g/1000 kcal/day)-as a reference, the adjusted odds ratio for DF and DKD for levels T2 (6.5-10.0 g/1000 kcal/day) and T3 (≥ 10.1 g/1000 kcal/day) were 0.97 (95%CI: 0.84-1.12, Conclusion: In United States adults with T2D, increased DF intake may be related to reduced DKD incidence. Further research is required to confirm these findings.
Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2583471-X
ISSN	1948-9358
ISSN	1948-9358
DOI	10.4239/wjd.v15.i3.475
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