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Article ; Online: Genome Sequence of Gordonia rubripertincta Phage Survivors, a Cluster CT Siphovirus.

Amend, Amber M / Bifone, Jacob P / Brewer, Justin C / Denton, Makayla N / Gilbert, Eden B / Grimm, Abigail C / Hogan, Jaden M / Kelley, Reagan M / Kelly-Brooner, Lennon J / Mukerji, Jit A / Osterhoudt, Matthew / Senn, Cody R / Smith, Bethanie R / Stillwell, Olive G / Vo, Jimmy / Watt, Danielle K / Connerly, Pamela L / Rueschhoff, Elizabeth E

Microbiology resource announcements

2023 Volume 12, Issue 1, Page(s) e0108622

Abstract: Bacteriophage Survivors is a siphovirus isolated from Gordonia rubripertincta NRRL B-16540. Survivors has a 45,436-bp genome encoding 69 predicted protein-coding genes, of which 32 have assigned functions. Based on gene content similarity to sequenced ... ...

Abstract	Bacteriophage Survivors is a siphovirus isolated from Gordonia rubripertincta NRRL B-16540. Survivors has a 45,436-bp genome encoding 69 predicted protein-coding genes, of which 32 have assigned functions. Based on gene content similarity to sequenced actinobacteriophages, Survivors is assigned to phage cluster CT.
Language	English
Publishing date	2023-01-04
Publishing country	United States
Document type	Journal Article
ISSN	2576-098X
ISSN (online)	2576-098X
DOI	10.1128/mra.01086-22
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Article ; Online: Competing Principles for Allocating Health Care Resources.

Carter, Drew / Gordon, Jason / Watt, Amber M

The Journal of medicine and philosophy

2016 Volume 41, Issue 5, Page(s) 558–583

Abstract: We clarify options for conceptualizing equity, or what we refer to as justice, in resource allocation. We do this by systematically differentiating, expounding, and then illustrating eight different substantive principles of justice. In doing this, we ... ...

Abstract	We clarify options for conceptualizing equity, or what we refer to as justice, in resource allocation. We do this by systematically differentiating, expounding, and then illustrating eight different substantive principles of justice. In doing this, we compare different meanings that can be attributed to "need" and "the capacity to benefit" (CTB). Our comparison is sharpened by two analytical tools. First, quantification helps to clarify the divergent consequences of allocations commended by competing principles. Second, a diagrammatic approach developed by economists Culyer and Wagstaff offers a visual and conceptual aid. Of the eight principles we illustrate, only two treat as relevant both a person's initial health state and a person's CTB per resource unit expended: (1) allocate resources so as to most closely equalize final health states and (2) allocate resources so as to equally restore health states to population norms. These allocative principles ought to be preferred to the alternatives if one deems relevant both a person's initial health state and a person's CTB per resource unit expended. Finally, we examine some possibilities for conceptualizing benefits as relative to how badly off someone is, extending Parfit's thought on Prioritarianism (a prioritizing of the worst off). Questions arise as to how much intervention effects accruing to the worse off count for more and how this changes with improving health. We explicate some recent efforts to answer these questions, including in Dutch and British government circles. These efforts can be viewed as efforts to operationalize need as an allocative principle. Each effort seeks to maximize in the aggregate quanta of effect that are differentially valued in favor of the worst off. In this respect, each effort constitutes one type of Prioritarianism, which Parfit failed to differentiate from other types.
MeSH term(s)	Bioethical Issues ; Decision Making ; Health Care Rationing/economics ; Health Care Rationing/ethics ; Health Policy ; Humans ; Models, Economic ; Social Values
Language	English
Publishing date	2016-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	197282-0
ISSN	1744-5019 ; 0360-5310
ISSN (online)	1744-5019
ISSN	0360-5310
DOI	10.1093/jmp/jhw017
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Article ; Online: The evidence for services to avoid or delay residential aged care admission: a systematic review.

Luker, Julie A / Worley, Anthea / Stanley, Mandy / Uy, Jeric / Watt, Amber M / Hillier, Susan L

BMC geriatrics

2019 Volume 19, Issue 1, Page(s) 217

Abstract: Background: Interventions that enable people to remain in their own home as they age are of interest to stakeholders, yet detailed information on effective interventions is scarce. Our objective was to systematically search and synthesise evidence for ... ...

Abstract	Background: Interventions that enable people to remain in their own home as they age are of interest to stakeholders, yet detailed information on effective interventions is scarce. Our objective was to systematically search and synthesise evidence for the effectiveness of community-based, aged care interventions in delaying or avoiding admission to residential aged care. Method: Nine databases were searched from January 2000 to February 2018 for English publications. Reference lists of relevant publications were searched. The databases yielded 55,221 citations and 50 citations were gleaned from other sources. Where there was sufficient homogeneity of study design, population, intervention and measures, meta-analyses were performed. Studies were grouped by the type of intervention: complex multifactorial interventions, minimal/single focus interventions, restorative programs, or by the target population (e.g. participants with dementia). Results: Data from 31 randomised controlled trials (32 articles) that met our inclusion criteria were extracted and analysed. Compared to controls, complex multifactorial interventions in community aged care significantly improved older adults' ability to remain living at home (risk difference - 0.02; 95% CI -0.03, - 0.00; p = 0.04). Commonalities in the 13 studies with complex interventions were the use of comprehensive assessment, regular reviews, case management, care planning, referrals to additional services, individualised interventions, frequent client contact if required, and liaison with General Practitioners. Complex interventions did not have a significantly different effect on mortality. Single focus interventions did not show a significant effect in reducing residential aged care admissions (risk difference 0, 95% CI -0.01, 0.01; p = 0.71), nor for mortality or quality of life. Subgroup analysis of complex interventions for people with dementia showed significant risk reduction for residential aged care admissions (RD -0.05; 95% CI -0.09, -0.01; p = 0.02). Compared to controls, only interventions targeting participants with dementia had a significant effect on improving quality of life (SMD 3.38, 95% CI 3.02, 3.74; p < 0.000001). Conclusions: Where the goal is to avoid residential aged care admission for people with or without dementia, there is evidence for multifactorial, individualised community programs. The evidence suggests these interventions do not result in greater mortality and hence are safe. Minimal, single focus interventions will not achieve the targeted outcomes. Trial registration: PROSPERO Registration CRD42016050086 .
MeSH term(s)	Aged ; Aged, 80 and over ; Case Management/standards ; Community Health Services/methods ; Community Health Services/standards ; Dementia/psychology ; Dementia/therapy ; Female ; Health Services Needs and Demand/standards ; Homes for the Aged/standards ; Hospitalization ; Humans ; Independent Living/psychology ; Independent Living/standards ; Male ; Patient Admission/standards ; Quality of Life/psychology ; Randomized Controlled Trials as Topic/methods ; Randomized Controlled Trials as Topic/psychology ; Residential Facilities/standards
Keywords	covid19
Language	English
Publishing date	2019-08-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-019-1210-3
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Article ; Online: Mortality in the first year of aged care services in Australia.

Inacio, Maria C / Lang, Catherine E / Khadka, Jyoti / Watt, Amber M / Crotty, Maria / Wesselingh, Steve / Whitehead, Craig

Australasian journal on ageing

2020 Volume 39, Issue 4, Page(s) e537–e544

Abstract: Objective: To examine the one-year mortality of Australians entering aged care services compared with the general population.: Methods: A population-based analysis evaluating one-year mortality among people who received first ever aged care services ... ...

Abstract	Objective: To examine the one-year mortality of Australians entering aged care services compared with the general population. Methods: A population-based analysis evaluating one-year mortality among people who received first ever aged care services in 2013 compared with the general population was conducted. Results: In 2013, 3.3 million Australians were ≥ 65 years and 34 919 (1%) entered permanent residential care, 23 288 (0.7%) respite care, 20 265 (0.6%) commenced home care packages, and 15 387 (0.5%) transition care. Individuals receiving aged care services had higher mortality than the general population, with those entering permanent residential care (age and sex direct standardised mortality rate ratio = 10.1, 95% CI: 9.8-10.5) having the greatest difference, followed by people accessing respite (7.2, 95% CI: 6.9-7.6), transition (4.6, 95% CI: 4.4-4.9) and home care (4.1, 95% CI: 3.9-4.4). Significant variation by sex and age was observed. Conclusion: Our study has identified significant variations in mortality rates that highlight which cohorts entering aged care are the most vulnerable.
MeSH term(s)	Aged ; Australia/epidemiology ; Delivery of Health Care ; Home Care Services ; Humans ; Respite Care ; Transitional Care
Language	English
Publishing date	2020-08-20
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1457406-8
ISSN	1741-6612 ; 0726-4240 ; 1440-6381
ISSN (online)	1741-6612
ISSN	0726-4240 ; 1440-6381
DOI	10.1111/ajag.12833
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Article ; Online: POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies.

Smallwood, Kelly / Watt, Kristin E N / Ide, Satoru / Baltrunaite, Kristina / Brunswick, Chad / Inskeep, Katherine / Capannari, Corrine / Adam, Margaret P / Begtrup, Amber / Bertola, Debora R / Demmer, Laurie / Demo, Erin / Devinsky, Orrin / Gallagher, Emily R / Guillen Sacoto, Maria J / Jech, Robert / Keren, Boris / Kussmann, Jennifer / Ladda, Roger /

Lansdon, Lisa A / Lunke, Sebastian / Mardy, Anne / McWalters, Kirsty / Person, Richard / Raiti, Laura / Saitoh, Noriko / Saunders, Carol J / Schnur, Rhonda / Skorvanek, Matej / Sell, Susan L / Slavotinek, Anne / Sullivan, Bonnie R / Stark, Zornitza / Symonds, Joseph D / Wenger, Tara / Weber, Sacha / Whalen, Sandra / White, Susan M / Winkelmann, Juliane / Zech, Michael / Zeidler, Shimriet / Maeshima, Kazuhiro / Stottmann, Rolf W / Trainor, Paul A / Weaver, K Nicole

American journal of human genetics

2023 Volume 110, Issue 5, Page(s) 809–825

Abstract: Heterozygous pathogenic variants in POLR1A, which encodes the largest subunit of RNA Polymerase I, were previously identified as the cause of acrofacial dysostosis, Cincinnati-type. The predominant phenotypes observed in the cohort of 3 individuals were ... ...

Abstract	Heterozygous pathogenic variants in POLR1A, which encodes the largest subunit of RNA Polymerase I, were previously identified as the cause of acrofacial dysostosis, Cincinnati-type. The predominant phenotypes observed in the cohort of 3 individuals were craniofacial anomalies reminiscent of Treacher Collins syndrome. We subsequently identified 17 additional individuals with 12 unique heterozygous variants in POLR1A and observed numerous additional phenotypes including neurodevelopmental abnormalities and structural cardiac defects, in combination with highly prevalent craniofacial anomalies and variable limb defects. To understand the pathogenesis of this pleiotropy, we modeled an allelic series of POLR1A variants in vitro and in vivo. In vitro assessments demonstrate variable effects of individual pathogenic variants on ribosomal RNA synthesis and nucleolar morphology, which supports the possibility of variant-specific phenotypic effects in affected individuals. To further explore variant-specific effects in vivo, we used CRISPR-Cas9 gene editing to recapitulate two human variants in mice. Additionally, spatiotemporal requirements for Polr1a in developmental lineages contributing to congenital anomalies in affected individuals were examined via conditional mutagenesis in neural crest cells (face and heart), the second heart field (cardiac outflow tract and right ventricle), and forebrain precursors in mice. Consistent with its ubiquitous role in the essential function of ribosome biogenesis, we observed that loss of Polr1a in any of these lineages causes cell-autonomous apoptosis resulting in embryonic malformations. Altogether, our work greatly expands the phenotype of human POLR1A-related disorders and demonstrates variant-specific effects that provide insights into the underlying pathogenesis of ribosomopathies.
MeSH term(s)	Humans ; Mice ; Animals ; Mandibulofacial Dysostosis/genetics ; Apoptosis ; Mutagenesis ; Ribosomes/genetics ; Phenotype ; Neural Crest/pathology ; Craniofacial Abnormalities/genetics ; Craniofacial Abnormalities/pathology
Language	English
Publishing date	2023-04-18
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	219384-x
ISSN	1537-6605 ; 0002-9297
ISSN (online)	1537-6605
ISSN	0002-9297
DOI	10.1016/j.ajhg.2023.03.014
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Article ; Online: Over 150 potentially low-value health care practices: an Australian study.

Elshaug, Adam G / Watt, Amber M / Mundy, Linda / Willis, Cameron D

The Medical journal of Australia

2011 Volume 197, Issue 10, Page(s) 556–560

Abstract: Objective: To develop and apply a novel method for scanning a range of sources to identify existing health care services (excluding pharmaceuticals) that have questionable benefit, and produce a list of services that warrant further investigation.: ... ...

Abstract	Objective: To develop and apply a novel method for scanning a range of sources to identify existing health care services (excluding pharmaceuticals) that have questionable benefit, and produce a list of services that warrant further investigation. Design and setting: A multiplatform approach to identifying services listed on the Australian Medicare Benefits Schedule (MBS; fee-for-service) that comprised: (i) a broad search of peer-reviewed literature on the PubMed search platform; (ii) a targeted analysis of databases such as the Cochrane Library and National Institute for Health and Clinical Excellence (NICE) "do not do" recommendations; and (iii) opportunistic sampling, drawing on our previous and ongoing work in this area, and including nominations from clinical and non-clinical stakeholder groups. Main outcome measures: Non-pharmaceutical, MBS-listed health care services that were flagged as potentially unsafe, ineffective or otherwise inappropriately applied. Results: A total of 5209 articles were screened for eligibility, resulting in 156 potentially ineffective and/or unsafe services being identified for consideration. The list includes examples where practice optimisation (ie, assessing relative value of a service against comparators) might be required. Conclusion: The list of health care services produced provides a launchpad for expert clinical detailing. Exploring the dimensions of how, and under what circumstances, the appropriateness of certain services has fallen into question, will allow prioritisation within health technology reassessment initiatives.
MeSH term(s)	Australia ; Health Services/standards ; Humans ; Insurance Benefits ; National Health Programs ; Patient Safety ; Quality of Health Care ; Unnecessary Procedures
Language	English
Publishing date	2011-03-28
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	186082-3
ISSN	1326-5377 ; 0025-729X
ISSN (online)	1326-5377
ISSN	0025-729X
DOI	10.5694/mja12.11083
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Ua VI Zs.398: Show issues

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Article ; Online: Assisted reproductive technologies: a systematic review of safety and effectiveness to inform disinvestment policy.

Watt, Amber M / Elshaug, Adam G / Willis, Cameron D / Hiller, Janet E

Health policy (Amsterdam, Netherlands)

2011 Volume 102, Issue 2-3, Page(s) 200–213

Abstract: Objective: Health policy relating to assisted reproductive technologies (ART) has been variably informed by clinical evidence, social values, political and fiscal considerations. This systematic review examined key factors associated with specific ... ...

Abstract	Objective: Health policy relating to assisted reproductive technologies (ART) has been variably informed by clinical evidence, social values, political and fiscal considerations. This systematic review examined key factors associated with specific benefits and harms of ART to inform the development of a model for generating policy recommendations within an Australian disinvestment research agenda. Methods: Six databases were searched from 1994 to 2009. Included articles contained data on safety and/or effectiveness of in vitro fertilisation (IVF) or IVF with intracytoplasmic sperm injection with reference to female age, male age or cycle rank. Narrative descriptions of key outcomes (live birth, miscarriage) were constructed alongside tabular summaries. Results: Sixty-eight studies and one registry report were included. There was substantial heterogeneity present within the evidence-base which limited the strength and scope of conclusions that could be drawn. However, this review does affirm the differential effectiveness associated with the ageing of ART patients with regard to live birth and miscarriage. Conclusion: From the available evidence, it was not possible to determine an explicit age or cycle rank that could be used to formulate defensible policy responsive to identified differential effectiveness. Stakeholder interpretation of this evidence-base may assist in developing policy that can incorporate uncertainty and reflect social values.
MeSH term(s)	Female ; Health Policy ; Humans ; Male ; Patient Safety ; Pregnancy ; Pregnancy Outcome ; Reproductive Techniques, Assisted/economics
Language	English
Publishing date	2011-10
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	605805-x
ISSN	1872-6054 ; 0168-8510
ISSN (online)	1872-6054
ISSN	0168-8510
DOI	10.1016/j.healthpol.2011.07.007
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Zs.B 2250: Show issues

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Article ; Online: Systematic review of computer-navigated total knee arthroplasty.

Zamora, Luis A / Humphreys, Karen J / Watt, Amber M / Forel, Deanne / Cameron, Alun L

ANZ journal of surgery

2013 Volume 83, Issue 1-2, Page(s) 22–30

Abstract: Background: Conventional total knee arthroplasty (TKA) and the more recently available computer-navigated total knee arthroplasty (CNTKA) use alternative methods to achieve correct limb alignment. This systematic review was undertaken to assess the ... ...

Abstract	Background: Conventional total knee arthroplasty (TKA) and the more recently available computer-navigated total knee arthroplasty (CNTKA) use alternative methods to achieve correct limb alignment. This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA. Methods: A systematic search of multiple databases identified relevant randomized controlled trials published to August 2012. Study inclusion was established through application of a predetermined protocol, with independent assessment by two reviewers. Results: Thirty randomized controlled trials were included. The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA. Conversion to conventional TKA was required in 1% of patients undergoing CNTKA. Thirteen trials reporting on satisfactory post-operative radiological alignment of the mechanical axis in the frontal plane were suitable for meta-analysis, which showed a significant total odds ratio (non-event) of 2.32 (95% confidence interval: 1.77-3.04) in favour of CNTKA (P < 0.00001). Clinical outcomes were comparable between the two techniques, with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements. Conclusions: At present, it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits. Although an assumption could be made that an improvement in post-operative alignment should lead to an improvement in patient-related outcomes, the available literature did not clearly show this. Further, long-term trials are required to address this issue.
MeSH term(s)	Arthroplasty, Replacement, Knee/methods ; Blood Loss, Surgical ; Humans ; Knee Joint/diagnostic imaging ; Knee Joint/physiology ; Odds Ratio ; Operative Time ; Outcome Assessment (Health Care) ; Postoperative Complications ; Radiography ; Randomized Controlled Trials as Topic ; Range of Motion, Articular ; Recovery of Function ; Surgery, Computer-Assisted
Language	English
Publishing date	2013-01
Publishing country	Australia
Document type	Comparative Study ; Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2050749-5
ISSN	1445-2197 ; 1445-1433 ; 0004-8682
ISSN (online)	1445-2197
ISSN	1445-1433 ; 0004-8682
DOI	10.1111/j.1445-2197.2012.06255.x
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Article ; Online: Engaging clinicians in evidence-based disinvestment: role and perceptions of evidence.

Watt, Amber M / Willis, Cameron D / Hodgetts, Katherine / Elshaug, Adam G / Hiller, Janet E

International journal of technology assessment in health care

2012 Volume 28, Issue 3, Page(s) 211–219

Abstract: Objectives: The aim of this study was to determine how evidence from systematic review (SR) is perceived and negotiated by expert stakeholders in considering a technology for potential disinvestment.: Methods: An evidence-informed stakeholder ... ...

Abstract	Objectives: The aim of this study was to determine how evidence from systematic review (SR) is perceived and negotiated by expert stakeholders in considering a technology for potential disinvestment. Methods: An evidence-informed stakeholder engagement examined results from a diagnostic accuracy SR of vitamin B12 and folate tests. Pathologists deliberated around the SR findings to generate an informed contribution to future policy for the funding of B12 and folate tests. Deliberations were transcribed and subject to qualitative analysis. Results: Pathologists did not engage with findings from the SR in depth; rather they sought to contest the terms of the problem driving the review and attempted to reframe it. Pathologists questioned the usefulness of SR outcomes given the variable definitions of B12 deficiency and deferred addressing disinvestment options specifically pertaining to B12 testing. However, folate testing was proffered as a potential disinvestment candidate, based upon pathologists' definition of "appropriate" evidence beyond the bounds of the SR. Conclusions: The value of SR to informing disinvestment deliberations by expert stakeholders may be a function of timing as well as content. Engagement of stakeholders in co-produced evidence may be required at two levels: (i) Early in the synthesis phase to help shape the SR and harmonize expert views with the available evidence (including gaps); (ii) Collaboration in primary research to fill evidence-gaps thus supporting evidence-based disinvestment. Without this, information asymmetry between clinically engaged experts and decision makers may preclude the collaborative, informed, and technical discussions required to generate productive policy change.
MeSH term(s)	Biomedical Technology ; Evidence-Based Medicine ; Folic Acid/blood ; Health Knowledge, Attitudes, Practice ; Health Personnel/psychology ; Humans ; Pathology, Clinical ; Policy Making ; Review Literature as Topic ; Vitamin B 12/blood
Chemical Substances	Folic Acid (935E97BOY8) ; Vitamin B 12 (P6YC3EG204)
Language	English
Publishing date	2012-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632573-7
ISSN	1471-6348 ; 0266-4623
ISSN (online)	1471-6348
ISSN	0266-4623
DOI	10.1017/S0266462312000402
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Article: Monitoring blood glucose levels in female mink during the reproductive cycle: 1. Prevention of hyperglycemia during the nursing period.

Hynes, Amber M J / Rouvinen-Watt, Kirsti

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire

2007 Volume 71, Issue 4, Page(s) 241–248

Abstract: Nursing sickness, the largest cause of death in female adult mink, is a metabolic disorder characterized by hyperglycemia. The impacts of body condition, dietary supplements, and reproductive status on the blood glucose concentration in female mink ... ...

Abstract	Nursing sickness, the largest cause of death in female adult mink, is a metabolic disorder characterized by hyperglycemia. The impacts of body condition, dietary supplements, and reproductive status on the blood glucose concentration in female mink during the reproductive cycle were investigated. Mink dams on 3 farms were assigned to receive either herring oil (HerO) or chromium picolinate (CrPic) or to be in a control group, receiving only the basal diet, for 6 wk at the onset of lactation. Hyperglycemia was observed throughout the reproductive cycle. Significant differences in blood glucose levels were observed between farms, emphasizing the importance of herd genetics and of animal management and feeding practices in glycemic regulation. Female mink exhibiting hyperglycemia early in the reproductive cycle tended to remain hyperglycemic and to have poorer health and fewer kits. Glucose levels > 7 mmol/L can be considered critical in this regard. Supplementing the diet with CrPic reduced the blood glucose concentration. Results from this study suggest that a diet containing high-quality n-3 polyunsaturated fatty acids, high levels of carbohydrate, and CrPic supplementation may help the nursing mink dam maintain a normal blood glucose concentration during lactation.
MeSH term(s)	Animal Nutritional Physiological Phenomena ; Animals ; Blood Glucose/metabolism ; Dietary Carbohydrates/administration & dosage ; Dietary Carbohydrates/metabolism ; Fatty Acids, Omega-3/administration & dosage ; Fatty Acids, Omega-3/metabolism ; Female ; Hyperglycemia/etiology ; Hyperglycemia/prevention & control ; Hyperglycemia/veterinary ; Lactation/blood ; Lactation/metabolism ; Litter Size ; Mink/blood ; Mink/physiology ; Nutritional Requirements ; Picolinic Acids/administration & dosage ; Picolinic Acids/metabolism
Chemical Substances	Blood Glucose ; Dietary Carbohydrates ; Fatty Acids, Omega-3 ; Picolinic Acids ; picolinic acid (QZV2W997JQ)
Language	English
Publishing date	2007-09-13
Publishing country	Canada
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	632814-3
ISSN	0830-9000
ISSN	0830-9000
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