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Article: Évaluation diaphragmatique par échographie.

Kharat, Aileen / Plojoux, Jérôme

2021 Volume 17, Issue 759, Page(s) 1962–1966

Abstract: Ultrasound of the diaphragm is an emerging technique that is performed at the bedside and allows assessment of diaphragm function in a variety of settings. Ultrasound is widely available, can be repeated if necessary, and is non-irradiating. First ... ...

Title translation	Diaphragmatic assessment by ultrasonography.
Abstract	Ultrasound of the diaphragm is an emerging technique that is performed at the bedside and allows assessment of diaphragm function in a variety of settings. Ultrasound is widely available, can be repeated if necessary, and is non-irradiating. First developed in intensive care, mainly for weaning from mechanical ventilation, its use is now extending to pulmonology. Different measurements are described such as diaphragmatic excursion, diaphragmatic thickness and diaphragmatic thickening fraction. The latter helps to diagnose dysfunction and is correlated with pulmonary hyperinflation. The main use in pulmonology is for the respiratory evaluation of patients with neuromuscular diseases, for the search of isolated diaphragmatic impairment and for patients with COPD. Numerous studies are in progress to better determine the role of diaphragmatic ultrasound.
MeSH term(s)	Critical Care ; Diaphragm/diagnostic imaging ; Humans ; Prospective Studies ; Respiration, Artificial ; Ultrasonography
Language	French
Publishing date	2021-11-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2177010-4
ISSN	1660-9379
ISSN	1660-9379
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Oxygénothérapie à domicile.

Brügger, Baptiste / Aouad, Soumaya / Geenens, Aurore / Kharat, Aileen-Margaret / Prella, Maura

Revue medicale suisse

2023 Volume 19, Issue 850, Page(s) 2153–2158

Abstract: Only severe hypoxemia at rest in COPD patients has strong recommendations for long-term oxygen therapy. It is accepted that oxygen should be prescribed if PaO2 is ≤ 7,3 kPa (55 mmHg), or if PaO2 is ≤ 8 kPa (60 mmHg) in the presence of signs of pulmonary ... ...

Title translation	Home oxygen therapy.
Abstract	Only severe hypoxemia at rest in COPD patients has strong recommendations for long-term oxygen therapy. It is accepted that oxygen should be prescribed if PaO2 is ≤ 7,3 kPa (55 mmHg), or if PaO2 is ≤ 8 kPa (60 mmHg) in the presence of signs of pulmonary hypertension or a hematocrit ≥ 55 %. In Switzerland, prescription is governed by the LiMA (Liste des moyens et appareils) and the patient can obtain supplies from a health care provider or directly from the provider. The most suitable device taking patient's oxygen needs and mobility into account must be chosen. O2 prescription entails risks for the patient that must be known to the prescriber. This article presents the different aspects of long-term home oxygen therapy.
MeSH term(s)	Humans ; Oxygen Inhalation Therapy ; Oxygen/therapeutic use ; Hypoxia/etiology ; Hypoxia/therapy ; Hypoxia/diagnosis ; Hypertension, Pulmonary/therapy ; Prescriptions
Chemical Substances	Oxygen (S88TT14065)
Language	French
Publishing date	2023-11-15
Publishing country	Switzerland
Document type	English Abstract ; Journal Article
ZDB-ID	2177010-4
ISSN	1660-9379
ISSN	1660-9379
DOI	10.53738/REVMED.2023.19.850.2153
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Article: POCUS : diagnostiquer la pneumonie par l’échographie pleuropulmonaire.

Sandoz, Ella / Soret, Guillaume / Kharat, Aileen / Marti, Christophe / Grosgurin, Olivier / Leidi, Antonio

Revue medicale suisse

2023 Volume 19, Issue 847, Page(s) 2008–2013

Abstract: Point-Of-Care Ultrasonography (POCUS) has emerged to support the diagnosis process and management strategies. Its use for the diagnosis of pneumonia has been shown to be reliable and effective over the past decade. Various ultrasonography patterns exist, ...

Title translation	POCUS : diagnosis of pneumonia by lung ultrasonography.
Abstract	Point-Of-Care Ultrasonography (POCUS) has emerged to support the diagnosis process and management strategies. Its use for the diagnosis of pneumonia has been shown to be reliable and effective over the past decade. Various ultrasonography patterns exist, none of which are pathognomonic for pneumonia. Therefore, POCUS findings must be interpreted in association with the clinical setting. POCUS enables early identification of complications such as parapneumonic effusion and pulmonary abscess. It also provides guidance for invasive procedure such as thoracocentesis and pleural drainage. The forthcoming results of the Swiss OCTOPLUS study will provide data on the clinical and economic impact of a diagnostic strategy based on targeted lung ultrasonography.
MeSH term(s)	Humans ; Point-of-Care Systems ; Pneumonia/diagnostic imaging ; Ultrasonography ; Drainage ; Lung/diagnostic imaging
Language	French
Publishing date	2023-10-25
Publishing country	Switzerland
Document type	English Abstract ; Journal Article
ZDB-ID	2177010-4
ISSN	1660-9379
ISSN	1660-9379
DOI	10.53738/REVMED.2023.19.847.2008
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Article: Volume Status Assessment by Lung Ultrasound in End-Stage Kidney Disease: A Systematic Review.

Kharat, Aileen / Tallaa, Faissal / Lepage, Marc-Antoine / Trinh, Emilie / Suri, Rita S / Mavrakanas, Thomas A

Canadian journal of kidney health and disease

2023 Volume 10, Page(s) 20543581231217853

Abstract: Purpose of review: Lung ultrasound is a noninvasive bedside technique that can accurately assess pulmonary congestion by evaluating extravascular lung water. This technique is expanding and is easily available. Our primary outcome was to compare the ... ...

Abstract	Purpose of review: Lung ultrasound is a noninvasive bedside technique that can accurately assess pulmonary congestion by evaluating extravascular lung water. This technique is expanding and is easily available. Our primary outcome was to compare the efficacy of volume status assessment by lung ultrasound with clinical evaluation, echocardiography, bioimpedance, or biomarkers. The secondary outcomes were all-cause mortality and cardiovascular events. Sources of information: We conducted a MEDLINE literature search for observational and randomized studies with lung ultrasound in patients on maintenance dialysis. Methods: From a total of 2363 articles, we included 28 studies (25 observational and 3 randomized). The correlation coefficients were pooled for each variable of interest using the generic inverse variance method with a random effects model. Among the clinical parameters, New York Heart Association Functional Classification of Heart Failure status and lung auscultation showed the highest correlation with the number of B-lines on ultrasound, with a pooled Key findings: Lung ultrasound may be considered for the identification of patients with subclinical volume overload. Trials did not show differences in clinically important outcomes. The number of studies was small and many were of suboptimal quality. Limitations: The included studies were heterogeneous and of relatively limited quality.
Language	English
Publishing date	2023-12-25
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2765462-X
ISSN	2054-3581
ISSN	2054-3581
DOI	10.1177/20543581231217853
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prone position in COVID 19-associated acute respiratory failure.

Kharat, Aileen / Simon, Marie / Guérin, Claude

Current opinion in critical care

2021 Volume 28, Issue 1, Page(s) 57–65

Abstract: Purpose of review: Prone position has been widely used in the COVID-19 pandemic, with an extension of its use in patients with spontaneous breathing ('awake prone'). We herein propose a review of the current literature on prone position in mechanical ... ...

Abstract	Purpose of review: Prone position has been widely used in the COVID-19 pandemic, with an extension of its use in patients with spontaneous breathing ('awake prone'). We herein propose a review of the current literature on prone position in mechanical ventilation and while spontaneous breathing in patients with COVID-19 pneumonia or COVID-19 ARDS. Recent findings: A literature search retrieved 70 studies separating whether patient was intubated (24 studies) or nonintubated (46 studies). The outcomes analyzed were intubation rate, mortality and respiratory response to prone. In nonintubated patient receiving prone position, the main finding was mortality reduction in ICU and outside ICU setting. Summary: The final results of the several randomized control trials completed or ongoing are needed to confirm the trend of these results. In intubated patients, observational studies showed that responders to prone in terms of oxygenation had a better survival than nonresponders.
MeSH term(s)	COVID-19 ; Humans ; Pandemics ; Prone Position ; Respiration, Artificial/adverse effects ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; SARS-CoV-2
Language	English
Publishing date	2021-10-26
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1235629-3
ISSN	1531-7072 ; 1070-5295
ISSN (online)	1531-7072
ISSN	1070-5295
DOI	10.1097/MCC.0000000000000900
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: High-flow nasal oxygen in acute hypoxemic respiratory failure: A narrative review of the evidence before and after the COVID-19 pandemic.

Genecand, Léon / Agoritsas, Thomas / Ehrensperger, Charlotte / Kharat, Aileen / Marti, Christophe

Frontiers in medicine

2022 Volume 9, Page(s) 1068327

Abstract: High-flow nasal oxygen (HFNO) is a type of non-invasive advanced respiratory support that allows the delivery of high-flow and humidified air through a nasal cannula. It can deliver a higher inspired oxygen fraction than conventional oxygen therapy (COT), ...

Abstract	High-flow nasal oxygen (HFNO) is a type of non-invasive advanced respiratory support that allows the delivery of high-flow and humidified air through a nasal cannula. It can deliver a higher inspired oxygen fraction than conventional oxygen therapy (COT), improves secretion clearance, has a small positive end-expiratory pressure, and exhibits a washout effect on the upper air space that diminishes dead space ventilation. HFNO has been shown to reduce the work of breathing in acute hypoxemic respiratory failure (AHRF) and has become an interesting option for non-invasive respiratory support. Evidence published before the COVID-19 pandemic suggested a possible reduction of the need for invasive mechanical ventilation compared to COT. The COVID-19 pandemic has resulted in a substantial increase in AHRF worldwide, overwhelming both acute and intensive care unit capacity in most countries. This triggered new trials, adding to the body of evidence on HFNO in AHRF and its possible benefits compared to COT or non-invasive ventilation. We have summarized and discussed this recent evidence to inform the best supportive strategy in AHRF both related and unrelated to COVID-19.
Language	English
Publishing date	2022-11-25
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2022.1068327
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Ultrasound-Derived Diaphragm Contractile Reserve as a Marker of Clinical Status in Patients With Cystic Fibrosis.

Gabrysz-Forget, Fanny / Maynard-Paquette, Anne-Catherine / Kharat, Aileen / Tremblay, François / Silviet-Carricart, Maité / Lavoie, Annick / Girard, Martin / Dubé, Bruno-Pierre

Frontiers in physiology

2022 Volume 12, Page(s) 808770

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2022-01-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2021.808770
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Implementing Lung Ultrasound in the Outpatient Management of COVID-19 Pneumonia: A Pilot Study to Update Local Guidelines.

Chevallier Lugon, Chloé / Kharat, Aileen / Soccal, Paola M / Guessous, Idris / Spechbach, Hervé / Salamun, Julien

Frontiers in medicine

2021 Volume 8, Page(s) 774035

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-11-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2021.774035
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Rethinking the efficacy of awake prone positioning in COVID-19-related acute hypoxaemic respiratory failure - Authors' reply.

Luo, Jian / Pavlov, Ivan / Tavernier, Elsa / Laffey, John G / Guerin, Claude / Vines, David / Perez, Yonatan / Roca, Oriol / Kharat, Aileen / McNicholas, Bairbre / Ibarra-Estrada, Miguel / Tan, Wei / Ehrmann, Stephan / Li, Jie

The Lancet. Respiratory medicine

2022 Volume 10, Issue 6, Page(s) e54

MeSH term(s)	COVID-19 ; Humans ; Patient Positioning ; Prone Position ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; Wakefulness
Language	English
Publishing date	2022-06-03
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2686754-0
ISSN	2213-2619 ; 2213-2600
ISSN (online)	2213-2619
ISSN	2213-2600
DOI	10.1016/S2213-2600(22)00167-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Implementing Lung Ultrasound in the Outpatient Management of COVID-19 Pneumonia

Chloé Chevallier Lugon / Aileen Kharat / Paola M. Soccal / Idris Guessous / Hervé Spechbach / Julien Salamun

Frontiers in Medicine, Vol

A Pilot Study to Update Local Guidelines

2021 Volume 8

Abstract: Background: Lung ultrasound (LUS) has a good performance with a high sensitivity and specificity for the diagnosis of pneumonia compared with chest X-ray, and it has been extensively used to assess patients during the COVID-19 pandemic. This study aims ... ...

Abstract	Background: Lung ultrasound (LUS) has a good performance with a high sensitivity and specificity for the diagnosis of pneumonia compared with chest X-ray, and it has been extensively used to assess patients during the COVID-19 pandemic. This study aims to evaluate the potential advantages of the regular use of LUS for the assessment of the severity and prognosis of COVID-19 pneumonia and to propose an adapted protocol with its inclusion in current local validated and published guidelines.Methods: This is a single-center prospective study conducted during the first (April–May 2020) and second (October 2020–January 2021) waves of the SARS-CoV2 pandemic in Switzerland. All adult patients presenting to dedicated test centers with a suspicion of mild-to-moderate COVID-19 pneumonia and not requiring hospitalization at the time of diagnosis were included. Patients with confirmed COVID-19 pneumonia were referred to an ambulatory follow-up unit at our institution for reassessment, with the inclusion of the use of LUS in a random selection. Descriptive statistics were calculated for demographics using percentages, means, and standard deviations according to the distribution of variables.Results: Eighty-eight ambulatory patients with a confirmed COVID-19 pneumonia were included (men = 57 [59%]; mean age, 52.1 ± 13.5 years). Among these, 19 (21%) were hospitalized and none died. Twenty-five lung assessments by ultrasound were performed during the follow-up consultation. All were consistent with the clinical examination and confirmed the clinician's opinion.Conclusion: The use of a standardized pleuro-pulmonary ultrasound protocol for ambulatory patients with COVID-19 could help to reduce the use of chest X-rays and improve overall management at the time of referral and eventual follow-up. However, a specific study including LUS in a systematic approach should be performed to evaluate the outcome of patients according to findings.
Keywords	COVID-19 ; lung ; ultrasound ; outpatient ; pneumonia ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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