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  1. Book ; Online: Niakhar, mémoires et perspectives : Recherches pluridisciplinaires sur le changement en Afrique

    Delaunay, Valérie / Desclaux, Alice / Sokhna, Cheikh

    2018  

    Abstract: Fondé en 1962 en zone rurale à 150 km de Dakar, en pays Sereer, lobservatoire de Niakhar est le plus ancien observatoire de population en Afrique encore en activité. Au cœur dune histoire scientifique et humaine originale, il a permis dassurer, depuis sa ...

    Abstract Fondé en 1962 en zone rurale à 150 km de Dakar, en pays Sereer, lobservatoire de Niakhar est le plus ancien observatoire de population en Afrique encore en activité. Au cœur dune histoire scientifique et humaine originale, il a permis dassurer, depuis sa création, le suivi sanitaire, démographique, social, économique et environnemental de plus de deux générations. Les résultats de recherche de Niakhar, avec des indicateurs suivis dans le temps long, ont éclairé et accompagné les politiques nationales et internationales en matière de santé, notamment pour la prévention du paludisme. En revisitant 50 années de recherche sur le site de Niakhar, cet ouvrage décrit et analyse la construction de cette plate-forme dobservation prospective pluridisciplinaire. Il illustre lintérêt de lapproche sur le long terme dans les différents domaines de recherche et ouvre une réflexion sur les enjeux éthiques particuliers à cet instrument de collecte. Enfin, il propose des pistes dévolution méthodologique et de gouvernance pour la recherche. Cette première synthèse sur lobservatoire de Niakhar permettra à lÉtat sénégalais et aux décideurs ouest-africains, avec les institutions internationales et les scientifiques, de disposer de bases concrètes pour optimiser ces plates-formes de recherche et les mobiliser dans la perspective des objectifs de développement durable
    Keywords Social sciences (General)
    Size 1 electronic resource ( pages)
    Publisher IRD Éditions
    Document type Book ; Online
    Note French ; Open Access
    HBZ-ID HT020677097
    ISBN 9782709926256 ; 2709926253
    DOI 10.4000/books.irdeditions.31277
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Senegal faces the coronavirus disease -19 challenge.

    Sokhna, Cheikh

    Travel medicine and infectious disease

    2020  Volume 37, Page(s) 101687

    MeSH term(s) Betacoronavirus ; COVID-19 ; Community Health Planning/organization & administration ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Hospital Bed Capacity ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; Senegal/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-04-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6236: Show issues Location:
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  4. Article ; Online: Molecular characterization of schistosome cercariae and their

    Senghor, Bruno / Webster, Bonnie / Pennance, Tom / Sène, Mariama / Doucouré, Souleymane / Sow, Doudou / Sokhna, Cheikh

    Current research in parasitology & vector-borne diseases

    2023  Volume 3, Page(s) 100114

    Abstract: ... Bulinus ... ...

    Abstract Bulinus senegalensis
    Language English
    Publishing date 2023-01-24
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-114X
    ISSN (online) 2667-114X
    DOI 10.1016/j.crpvbd.2023.100114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Malaria epidemics associated with low net use in preadolescent and young adult population in Dielmo (Senegal), a malaria pre-elimination area.

    Wotodjo, Amélé Nyedzie / Doucoure, Souleymane / Diagne, Nafissatou / Sarr, Fatoumata Diene / Sokhna, Cheikh

    Parasites & vectors

    2024  Volume 17, Issue 1, Page(s) 74

    Abstract: Background: The epidemic rebounds observed in 2010 and 2013 in Dielmo, a Senegalese village, during a decade (2008-2019) of universal coverage using a long-lasting insecticidal net (LLIN) strategy could have contributed to the resurgence of malaria. ... ...

    Abstract Background: The epidemic rebounds observed in 2010 and 2013 in Dielmo, a Senegalese village, during a decade (2008-2019) of universal coverage using a long-lasting insecticidal net (LLIN) strategy could have contributed to the resurgence of malaria. Thus, this study was undertaken to understand the implications of net ownership and use on malaria rebound events.
    Methods: A longitudinal study was carried out in Dielmo with 11 years of LLIN implementation from July 2008 to June 2019 with successive net renewals in 2011, 2014, 2016 and 2019. Quarterly cross-sectional surveys were performed to assess LLIN ownership and use by different age groups in the population. In addition, malaria incidence and transmission were assessed during the study period.
    Results: Ownership of LLINs decreased significantly from 88% in the 1st year of net implementation to 70% during the first malaria upsurge and 72% during the second upsurge while net use decreased significantly from 66% during the 1st year to 58% during the first malaria upsurge and 53% during the second upsurge. Among young adults aged 15-29 years, net use decreased significantly from the 2nd year (51%) of net use to reach 43% during the first malaria upsurge and only 32% use during the second malaria upsurge. During the second malaria upsurge, net use was significantly lower among older children aged 10-14 years old than during the 1st year of net use (p < 0.001). During the first and the second malaria upsurges, the malaria incidence was significantly higher among children aged 10-14 years old (0.4 attacks per person-year) and young adults aged 15-29 years old (0.3 and 0.4 attacks per person, respectively) than during that the 1st year of net implementation (only 0.02 attacks per person-year for 10-14 year olds and 0.04 for 15-29 year olds; p < 0.001).
    Conclusions: The first malaria upsurge occurred following a progressive decrease in net use after the 2nd year of their implementation with an important increase in malaria incidence among older children while the second malaria upsurge was significantly associated with the decrease of net use among older children and young adults. The regular use of nets in all age groups prevented the occurrence of a third malaria upsurge in Dielmo.
    MeSH term(s) Child ; Humans ; Young Adult ; Adolescent ; Adult ; Senegal/epidemiology ; Cross-Sectional Studies ; Longitudinal Studies ; Insecticide-Treated Bednets ; Mosquito Control ; Malaria/epidemiology ; Malaria/prevention & control ; Insecticides
    Chemical Substances Insecticides
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2409480-8
    ISSN 1756-3305 ; 1756-3305
    ISSN (online) 1756-3305
    ISSN 1756-3305
    DOI 10.1186/s13071-024-06172-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Carbonyl Cyanide 3-Chloro Phenyl Hydrazone (CCCP) Restores the Colistin Sensitivity in

    Zoaiter, Malak / Zeaiter, Zaher / Mediannikov, Oleg / Sokhna, Cheikh / Fournier, Pierre-Edouard

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: ... Brucella ... ...

    Abstract Brucella intermedia
    MeSH term(s) Humans ; Colistin/pharmacology ; Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology ; Hydrazones ; Anti-Bacterial Agents/pharmacology ; Brucella ; Microbial Sensitivity Tests
    Chemical Substances Colistin (Z67X93HJG1) ; mesoxalonitrile (1115-12-4) ; Carbonyl Cyanide m-Chlorophenyl Hydrazone (555-60-2) ; Hydrazones ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Using MALDI-TOF MS to Identify Mosquitoes from Senegal and the Origin of Their Blood Meals.

    Fall, Fatou Kiné / Diarra, Adama Zan / Bouganali, Charles / Sokhna, Cheikh / Parola, Philippe

    Insects

    2023  Volume 14, Issue 10

    Abstract: Mosquitoes are arthropods that represent a real public health problem in Africa. Morphology and molecular biology techniques are usually used to identify different mosquito species. In recent years, an innovative tool, matrix-assisted desorption/ ... ...

    Abstract Mosquitoes are arthropods that represent a real public health problem in Africa. Morphology and molecular biology techniques are usually used to identify different mosquito species. In recent years, an innovative tool, matrix-assisted desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), has been used to identify many arthropods quickly and at low cost, where equipment is available. We evaluated the ability of MALDI-TOF MS to identify mosquitoes collected in Senegal and stored for several months in silica gel, and to determine the origin of their blood meal. A total of 582 mosquitoes were collected and analysed. We obtained 329/582 (56.52%) MALDI-TOF MS good-quality spectra from mosquito legs and 123/157 (78.34%) good-quality spectra from engorged abdomens. We updated our home-made MALDI-TOF MS arthropod spectra database by adding 23 spectra of five mosquito species from Senegal that had been identified morphologically and molecularly. These included legs from
    Language English
    Publishing date 2023-09-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects14100785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Ornithodoros sonrai

    Ndiaye, El Hadji Ibrahima / Diarra, Adama Zan / Diouf, Fatou Samba / Bouganali, Charles / Almeras, Lionel / Sokhna, Cheikh / Diatta, Georges / Parola, Philippe

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: The soft ticks, ...

    Abstract The soft ticks,
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12091078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Epidemiology of bacterial resistance at the Grand Magal of Touba in Senegal.

    Ouaddane, Ihssane / Goumballa, Ndiaw / Tran, Xuan Duong / Diouf, Coumba / Diene, Seydina M / Rolain, Jean-Marc / Sokhna, Cheikh / Gautret, Philippe

    Travel medicine and infectious disease

    2024  Volume 59, Page(s) 102709

    Abstract: Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted.: Materials and methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 ... ...

    Abstract Background: The Grand Magal of Touba (GMT) associates with risks of infection, but no study on the circulation of resistant bacteria has yet been conducted.
    Materials and methods: qPCR was performed on rectal samples from GMT pilgrims between 2018 and 2021, before and after their participation in the gathering. Rectal samples from between 2018 and 2020 were also cultured on specific media, and antibiotic susceptibility testing was performed.
    Results: Forty-one of the 296 (13.8%) pilgrims had at least one gastrointestinal symptom and 91/290 (31.4%) acquired pathogenic bacteria, mostly Escherichia coli. A total of 54.7% of pilgrims reported washing their hands more frequently than usual and 89.2% used soap. One hundred and five (36.2%) acquired at least one resistance gene, notably CTX-M A (21.0%), SHV (16.5%) and TEM (8.2%). The strains isolated by culture were mostly E. coli. These bacteria were found to be sensitive to carbapenems and resistant to amoxicillin and amoxicillin-clavulanic acid. The acquisition of enteroaggregative E. coli was independently associated with CTX-M A and TEM acquisition.
    Conclusion: Pilgrims presented a risk for acquisition of CTX-M A after the GMT. Surveillance of the prevalence of resistant bacteria and the occurrence of associated clinical infections among pilgrims are necessary in the future.
    Language English
    Publishing date 2024-03-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2024.102709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Seasonal variation of asymptomatic viral and bacterial nasopharyngeal carriage in rural Senegal.

    Diouf, Fatou Samba / Tidjani Alou, Maryam / Bassene, Hubert / Cortaredona, Sebastien / Diatta, Georges / Raoult, Didier / Sokhna, Cheikh / Lagier, Jean-Christophe

    Journal of infection and public health

    2024  Volume 17, Issue 5, Page(s) 922–928

    Abstract: Background: The surveillance of respiratory pathogens in rural areas of West Africa has, to date, largely been focussed on symptoms. In this prospective study conducted prior to the COVID-19 pandemic, we aimed to assess the asymptomatic prevalence of ... ...

    Abstract Background: The surveillance of respiratory pathogens in rural areas of West Africa has, to date, largely been focussed on symptoms. In this prospective study conducted prior to the COVID-19 pandemic, we aimed to assess the asymptomatic prevalence of respiratory pathogen carriage in a group of individuals living in a rural area of Senegalese.
    Methods: Longitudinal follow up was performed through monthly nasopharyngeal swabbing during the dry season and weekly swabbing during the rainy season. We enrolled 15 individuals from the village of Ndiop. A total of 368 nasopharyngeal swabs were collected over a one-year period. We investigated the prevalence of 18 respiratory viruses and eight respiratory bacteria in different age groups using singleplex and multiplex PCR.
    Results: In total, 19.56% of the samples (72/368) were positive for respiratory viruses and 13.60% of the samples (50/368) were positive for respiratory bacteria. Coronaviruses (19/72, 26.39%), adenoviruses (17/72, 23.61%), rhinoviruses (14/72, 19.44%), Streptococcus pneumoniae (17/50, 34%), and Moraxella catarrhalis (15/50, 30%) were the most frequently detected viruses. Interestingly, the carriage of respiratory pathogens was shown to be more frequent during the rainy season, as pluviometry was shown to be positively associated with the occurrence of respiratory viruses such as influenza (P = .0078, r
    Conclusions: Our results show a non-negligible circulation of respiratory pathogens in a rural area in Senegal (West Africa) with an underestimated proportion of asymptomatic individuals. This study highlights the fact that the circulation of viruses and bacteria in the community has been overlooked.
    MeSH term(s) Humans ; Infant ; Seasons ; Respiratory Tract Infections ; Senegal/epidemiology ; Prospective Studies ; Pandemics ; Nasopharynx ; Bacteria ; Viruses
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2024.03.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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