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  1. Article ; Online: Progression of LSIL to HSIL or SCC: is anoscopy and biopsy good enough?

    Mistrangelo, M / Salzano, A

    Techniques in coloproctology

    2019  Volume 23, Issue 4, Page(s) 303–304

    MeSH term(s) Anal Canal/pathology ; Anal Canal/surgery ; Anus Neoplasms/diagnosis ; Biopsy/methods ; Carcinoma in Situ/diagnosis ; Carcinoma, Squamous Cell/diagnosis ; Early Detection of Cancer/methods ; Endoscopy, Gastrointestinal/methods ; Humans
    Language English
    Publishing date 2019-05-18
    Publishing country Italy
    Document type Editorial
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-019-02001-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Role of High-resolution Anoscopy and Random Biopsies: The Role of Infrared Coagulation vs Active Monitoring in the Treatment of High-grade Squamous Intraepithelial Lesions.

    Mistrangelo, Massimiliano / Dal Conte, Ivano

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2019  Volume 70, Issue 5, Page(s) 987

    MeSH term(s) Acquired Immunodeficiency Syndrome ; Adult ; Anus Neoplasms ; Biopsy ; HIV ; Humans ; Proctoscopy ; Squamous Intraepithelial Lesions
    Language English
    Publishing date 2019-05-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciz487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Do we really need guidelines for HRA during the COVID-19 pandemic?

    Mistrangelo, M / Naldini, G / Morino, M

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 6, Page(s) 647–648

    MeSH term(s) Anus Neoplasms/diagnosis ; Anus Neoplasms/pathology ; Betacoronavirus ; Biopsy ; COVID-19 ; Carcinoma/diagnosis ; Carcinoma/pathology ; Carcinoma in Situ/diagnosis ; Carcinoma in Situ/pathology ; Coronavirus Infections ; Digital Rectal Examination ; Disease Progression ; Endoscopy, Gastrointestinal ; Humans ; Pandemics ; Pneumonia, Viral ; Practice Guidelines as Topic ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-25
    Publishing country England
    Document type Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comment on: "Safety of Small Circular Staplers in Double Stapling Technique Anastomosis for Sigmoid Colon and Rectal Surgery".

    Resegotti, Andrea / Allaix, Marco E / Mistrangelo, Massimiliano / Morino, Mario

    Diseases of the colon and rectum

    2021  Volume 65, Issue 4, Page(s) e246

    MeSH term(s) Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/methods ; Colon, Sigmoid/surgery ; Humans ; Rectal Neoplasms/surgery
    Language English
    Publishing date 2021-12-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000002402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk factors for Low Anterior Resection Syndrome (LARS) in patients undergoing laparoscopic surgery for rectal cancer.

    Nicotera, Antonella / Falletto, Ezio / Arezzo, Alberto / Mistrangelo, Massimiliano / Passera, Roberto / Morino, Mario

    Surgical endoscopy

    2022  Volume 36, Issue 8, Page(s) 6059–6066

    Abstract: Background: Total mesorectal excision (TME) represents the "gold standard" of rectal cancer surgery. In locally advanced lesions neoadjuvant treatments (e.g. radiotherapy-nRT, radio chemotherapy-cnRT) have been shown to improve TME oncological results, ... ...

    Abstract Background: Total mesorectal excision (TME) represents the "gold standard" of rectal cancer surgery. In locally advanced lesions neoadjuvant treatments (e.g. radiotherapy-nRT, radio chemotherapy-cnRT) have been shown to improve TME oncological results, reducing local recurrences rate. Nevertheless, these treatments have significant functional consequences impacting patients' quality of life (QoL). The resulting syndrome is known as Low Anterior Resection Syndrome (LARS). The purpose of this work was to evaluate the association between risk factors and the development of LARS in a prospective series of laparoscopic sphincter-saving TME.
    Methods: The study was conducted as a retrospective observational epidemiological study of a prospective database, including all patients undergoing laparoscopic anterior resection surgery for rectal cancer at our Unit from 1st January 2013 to 31st May 2018. The diagnosis of LARS was performed using the LARS Score. We classified risk factors in patient-related, pre-, intra- and post-operative factors.
    Results: The sample included 153 consecutive patients. Forty-one were affected by "low" rectal cancer, 74 by "middle" rectal cancer, 38 by "high" rectal cancer. The prevalence of overall LARS (major LARS + minor LARS) in our series was 35.9% (55/153 cases). Association between nRT and overall/major LARS was significant (respectively p = 0.03 and 0.02). Distal localization of tumor was also significantly associated with LARS [overall LARS (p = 0.03), major LARS (p = 0.014)].
    Conclusions: In our study, neoadjuvant radiotherapy and tumor localization resulted independent risk factors for LARS after laparoscopic sphincter-saving TME. Tumor localization in the "middle" and "high" rectum resulted a protective factor compared to the localization in "low" rectum.
    MeSH term(s) Humans ; Laparoscopy/adverse effects ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Quality of Life ; Rectal Diseases/surgery ; Rectal Neoplasms/pathology ; Rectal Neoplasms/surgery ; Rectum/pathology ; Rectum/surgery ; Retrospective Studies ; Risk Factors ; Syndrome
    Language English
    Publishing date 2022-02-08
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-021-09002-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Surgical treatment of anal condylomata acuminata.

    Mistrangelo, Massimiliano

    Diseases of the colon and rectum

    2009  Volume 52, Issue 10, Page(s) 1803; author reply 1803

    MeSH term(s) Adult ; Aged ; Anus Diseases/pathology ; Anus Diseases/surgery ; Cautery/instrumentation ; Condylomata Acuminata/pathology ; Condylomata Acuminata/surgery ; Constriction, Pathologic ; Fecal Incontinence/etiology ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications/etiology ; Recurrence ; Ultrasonic Therapy/instrumentation
    Language English
    Publishing date 2009-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1007/DCR.0b013e3181ab3185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Do we really need guidelines for HRA during the COVID-19 pandemic?

    Mistrangelo M. / Naldini G. / Morino M.

    2020  

    Keywords covid19
    Language English
    Publishing country it
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Do we really need guidelines for HRA during the COVID‐19 pandemic?

    Mistrangelo, M. / Naldini, G. / Morino, M.

    Colorectal Disease

    2020  Volume 22, Issue 6, Page(s) 647–648

    Keywords Gastroenterology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15116
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Intracorporeal or extracorporeal ileocolic anastomosis after laparoscopic right colectomy: cost analysis of the Torino trial.

    Seno, Elisabetta / Allaix, Marco Ettore / Ammirati, Carlo Alberto / Bonino, Marco Augusto / Arezzo, Alberto / Mistrangelo, Massimiliano / Morino, Mario

    Surgical endoscopy

    2022  Volume 37, Issue 1, Page(s) 479–485

    Abstract: Background: Intracorporeal (IIA) and extracorporeal anastomosis (EIA) are two well-established techniques for restoration of bowel continuity after laparoscopic right colectomy (LRC). Since no economic analysis comparing the two different anastomotic ... ...

    Abstract Background: Intracorporeal (IIA) and extracorporeal anastomosis (EIA) are two well-established techniques for restoration of bowel continuity after laparoscopic right colectomy (LRC). Since no economic analysis comparing the two different anastomotic techniques has been performed yet, it is still unclear if IIA can reduce perioperative costs. The aim of the study was to compare costs of LRC with IIA or EIA for right-sided colon neoplasm.
    Methods: This is a cost analysis of a single-institution double-blinded randomized controlled trial comparing the outcomes of LRC with IIA and LRC with EIA in patients with a right-sided colon neoplasm. All direct in-hospital costs related to patient's admission were recorded (intraoperative costs: operative room, surgical tools, blood units-postoperative costs: hospital stay, laboratory and microbiology analyses, diagnostic services, analgesic drugs and antibiotic therapy, blood units, reoperation-outpatient costs: post-discharge wound medications). This trial was registered with ClinicalTrials.gov, Number NCT03045107.
    Results: A total of 140 patients were randomized and analyzed. Mean overall costs in the IIA group exceeded 349 € the mean overall costs of the EIA group (7926.87 ± 4617.23 € vs. 7577.45 ± 6131.17 €; P = 0.704). A mean extra charge of 608 € regarding total intraoperative costs was recorded in the IIA group (3058.84 ± 897.42 € vs. 2450.15 ± 558.90 €; P < 0.001). The cost of surgical instruments resulted in 542 € additional charge per patient in the IIA group compared to EIA group (1782.74 ± 541.26 € vs. 1240.55 ± 384.09 €; P < 0.001). The mean cost of operative room occupancy was comparable in IIA and EIA group: 1276.09 ± 514.94 € vs. 1209.60 ± 422.80 € (P = 0.405). No significant differences were observed in postoperative costs and in outpatient costs.
    Conclusion: This economic analysis showed that IIA and EIA after LRC had similar overall costs, even though there were intraoperative extra costs of IIA.
    MeSH term(s) Humans ; Aftercare ; Colonic Neoplasms/surgery ; Laparoscopy/methods ; Patient Discharge ; Colectomy/methods ; Anastomosis, Surgical/methods ; Costs and Cost Analysis ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2022-08-23
    Publishing country Germany
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-022-09546-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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