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  1. Article ; Online: Signal Processing Circuits and Systems for Smart Sensing Applications.

    Herencsar, Norbert / Salama, Khaled N

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 12

    Abstract: The rising demand for reliable, real-time, low-maintenance, cost-efficient monitoring systems with a high accuracy is becoming increasingly more notable in everyday life [ ... ]. ...

    Abstract The rising demand for reliable, real-time, low-maintenance, cost-efficient monitoring systems with a high accuracy is becoming increasingly more notable in everyday life [...].
    MeSH term(s) Signal Processing, Computer-Assisted ; Monitoring, Ambulatory
    Language English
    Publishing date 2023-06-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23125492
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  2. Article ; Online: Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia.

    Aref, Salah / Khaled, Omnyia / Menshawy, Nadia El / Azmy, Emad / Aref, Mohamed / Salama, Osama / Khaled, Nada

    Journal of the Egyptian National Cancer Institute

    2024  Volume 36, Issue 1, Page(s) 5

    Abstract: Objective: This study aimed to address the prognostic impact of SOX2 and OCT3/4 expression on adult acute leukemia patients' outcomes.: Methods: SOX2 and OCT3/4 expression by blast cells were evaluated by flow cytometry in 80 acute leukemia patients ... ...

    Abstract Objective: This study aimed to address the prognostic impact of SOX2 and OCT3/4 expression on adult acute leukemia patients' outcomes.
    Methods: SOX2 and OCT3/4 expression by blast cells were evaluated by flow cytometry in 80 acute leukemia patients and 8 healthy controls.
    Results: Baseline SOX2 and OCT3/4 expression were significantly higher in both ALL (P = < 0.001, P = 0.005 respectively) and AML patients (P < 0.001, P = 0.003 respectively) as compared to control, and decline at complete remission (CR) and elevated again at relapse. High SOX2 and OCT3/4 levels were significantly correlated with the presence of adverse risk stratification parameters.
    Conclusion: Our findings indicated that both SOX2 and OCT3/4 could serve as biomarkers that could improve risk stratification of acute leukemia patients. Also, both SOX2 and OCT3/4 might be a therapeutic target, especially in resistant acute leukemia.
    MeSH term(s) Adult ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Prognosis ; SOXB1 Transcription Factors/genetics
    Chemical Substances SOX2 protein, human ; SOXB1 Transcription Factors
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1176790-x
    ISSN 2589-0409 ; 1110-0362
    ISSN (online) 2589-0409
    ISSN 1110-0362
    DOI 10.1186/s43046-024-00209-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3918: Show issues Location:
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  3. Article ; Online: Apigenin ameliorates genitourinary dysfunction in a type 1 diabetic rat model via Drp1 modulation.

    Khaled, Mai / Salama, Raghda A M / Aboughalia, Azza / Tarek, Mai / Mohamed Fawzy, Nesma

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5754

    Abstract: The present study aimed to explore the potential ameliorative effect of apigenin (APG) against diabetes-associated genitourinary complications in rats. A diabetic rat model was induced by the intraperitoneal injection of streptozotocin (STZ). All ... ...

    Abstract The present study aimed to explore the potential ameliorative effect of apigenin (APG) against diabetes-associated genitourinary complications in rats. A diabetic rat model was induced by the intraperitoneal injection of streptozotocin (STZ). All experimental animals were treated with vehicle or vehicle plus APG at a dose of 0.78 mg/kg/day for 10 days, either once diabetes was confirmed or at the end of the 3rd week after confirmation of diabetes. Rats were sacrificed at the end of the fifth week. In addition to the histological assessment, an analysis of kidney function tests and serum testosterone was performed to assess diabetic genitourinary complications. Gene expression of the mitochondrial fission protein, dynamin related protein 1 (Drp1), was measured in renal and testicular tissues using qRT PCR. APG can increase body weight, reduce blood glucose levels, and improve renal and testicular functions in diabetic rats. APG decreased Drp1 overexpression in diabetic animals' kidneys and testes. In summary, our current work discloses that APG attenuates diabetic genitourinary lesions in rats via suppressing Drp1 overexpression.
    MeSH term(s) Rats ; Animals ; Apigenin/pharmacology ; Apigenin/therapeutic use ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/pathology ; Kidney/metabolism ; Dynamins/metabolism ; Diabetic Nephropathies/pathology
    Chemical Substances Apigenin (7V515PI7F6) ; Dynamins (EC 3.6.5.5)
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56395-6
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  4. Article: Purification of Ambient Air by Novel Green Plant with Titanium Dioxide Nanoparticles.

    Salama, Khaled F / Zafar, Mubashir

    International journal of preventive medicine

    2022  Volume 13, Page(s) 67

    Abstract: Background: Indoor air pollution is an important environmental health problem. Nanotechnology is one of the most important methods to reduce the indoor air pollution. Titanium dioxide (TiO: Methods: Experiments were conducted in two academic ... ...

    Abstract Background: Indoor air pollution is an important environmental health problem. Nanotechnology is one of the most important methods to reduce the indoor air pollution. Titanium dioxide (TiO
    Methods: Experiments were conducted in two academic departments of the laboratories at the Public Sector University. Concentration of formaldehyde, nitrogen dioxide (NO
    Results: It was found that the levels of formaldehyde, volatile organic compounds (VOCs) and other pollutants were significantly reduced the concentration from 10% to 98% in the air. After intervention, air containing the concentration of formaldehyde, TVOCs, NO
    Conclusions: Significant reduction of air pollutants in the air after application of TiO
    Language English
    Publishing date 2022-04-08
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
    DOI 10.4103/ijpvm.IJPVM_586_20
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  5. Article ; Online: Cold plasma approach fortifies the topical application of thymoquinone intended for wound healing via up-regulating the levels of TGF-ß, VEGF, and α-SMA in rats.

    Sedik, Ahmed A / Salama, Mohamed / Fathy, Khaled / Salama, Abeer

    International immunopharmacology

    2023  Volume 122, Page(s) 110634

    Abstract: Wound healing is a series of coordinated events that involve tissue repair and regeneration. Cold atmospheric plasma approach sheds the light on the mechanism that initiates the inflammatory responses throughout the healing cascade. The present study was ...

    Abstract Wound healing is a series of coordinated events that involve tissue repair and regeneration. Cold atmospheric plasma approach sheds the light on the mechanism that initiates the inflammatory responses throughout the healing cascade. The present study was planned to assess the effect of thymoquinone treated with cold plasma (TQcp) on the rat wound model compared to thymoquinone (TQ). To assess the wound healing potential of TQcp, a full-thickness wound model was used. The induced wound was smeared, starting just after excision, twice daily with TQcp and TQ for 7 days. Our findings revealed that TQcp improved the skin healing potential by augmenting the skin regeneration indices as evidenced by enhancing the new production of hyaluronic acid and collagen type I. TQcp significantly reduced the skin content of tumor necrosis factor- α and inhibited the hypertrophic scarring by up-regulating the skin content of transforming growth factor-beta. Furthermore, TQcp enhanced the levels of interleukin-10, alpha smooth muscle actin and vascular endothelial growth factor, demonstrating a great potential for wound healing that also reflected in the histopathological and ultra-structural picture of the skin. Finally, our results demonstrated that TQcp revealed a significant potential for wound healing than TQ alone.
    MeSH term(s) Rats ; Animals ; Vascular Endothelial Growth Factor A/metabolism ; Plasma Gases/metabolism ; Plasma Gases/pharmacology ; Actins/metabolism ; Wound Healing ; Skin/pathology ; Tumor Necrosis Factor-alpha/metabolism
    Chemical Substances Vascular Endothelial Growth Factor A ; Plasma Gases ; thymoquinone (O60IE26NUF) ; Actins ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2023-07-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2023.110634
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5408: Show issues Location:
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  6. Article ; Online: Biomarkers of oral subacute toxicity of deltamethrin in exposed male Albino rats.

    Elbanna, Rania / Osman, Khaled A / Salama, Maher S

    Toxicology and industrial health

    2023  Volume 39, Issue 12, Page(s) 735–753

    Abstract: Deltamethrin is one of the most effective pyrethroid compounds, widely employed in veterinary medicine, public health, and farming. Deltamethrin-triggered oxidative stress largely causes serious harm to an organism. Acute toxicity of this compound was ... ...

    Abstract Deltamethrin is one of the most effective pyrethroid compounds, widely employed in veterinary medicine, public health, and farming. Deltamethrin-triggered oxidative stress largely causes serious harm to an organism. Acute toxicity of this compound was extensively investigated, while less information is available on its oral sub-acute effects. This study assessed, in the male Albino rats, the effects of oral gavage of either 0.874 mg/kg (0.01 LD
    MeSH term(s) Rats ; Male ; Animals ; Antioxidants/pharmacology ; Pyrethrins/toxicity ; Oxidative Stress ; Kidney ; Inflammation/metabolism ; Liver ; Biomarkers/metabolism ; Lipid Peroxidation
    Chemical Substances decamethrin (2JTS8R821G) ; Antioxidants ; Pyrethrins ; Biomarkers
    Language English
    Publishing date 2023-10-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 56831-4
    ISSN 1477-0393 ; 0748-2337
    ISSN (online) 1477-0393
    ISSN 0748-2337
    DOI 10.1177/07482337231209360
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    Zs.A 2268: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Book ; Online ; Thesis: Validierungsstudie zur Differentialdiagonstik von bakterieller Arthritis und Gicht-Arthritis aus Einzelparametern im Gelenkspunktat

    Salama, Khaled [Verfasser] / Scherer, Michael [Akademischer Betreuer]

    2023  

    Author's details Khaled Salama ; Betreuer: Michael Scherer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
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  8. Article ; Online: Effect of combining UV-C irradiation and vacuum sealing on the shelf life of fresh strawberries and tomatoes.

    Damdam, Asrar / Al-Zahrani, Ashwaq / Salah, Lama / Salama, Khaled Nabil

    Journal of food science

    2023  Volume 88, Issue 2, Page(s) 595–607

    Abstract: This research presents the effect of combining UV-C irradiation and vacuum sealing on the shelf life of strawberries and quartered tomatoes and compares it with the effect of the sole use of UV-C irradiation or vacuum sealing. A constant UV-C dose of 360 ...

    Abstract This research presents the effect of combining UV-C irradiation and vacuum sealing on the shelf life of strawberries and quartered tomatoes and compares it with the effect of the sole use of UV-C irradiation or vacuum sealing. A constant UV-C dose of 360 J/m
    MeSH term(s) Food Packaging/methods ; Solanum lycopersicum ; Fragaria ; Negative-Pressure Wound Therapy ; Taste ; Food Preservation/methods ; Food Microbiology ; Colony Count, Microbial
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241615-3
    ISSN 1750-3841 ; 0022-1147
    ISSN (online) 1750-3841
    ISSN 0022-1147
    DOI 10.1111/1750-3841.16444
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    Zs.A 1001: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article: Mobile schwannoma of the thoracolumbar spine: A case report.

    Mohamed, Hazem A / Elboraay, Toka / Abualkhair, Khaled Alsayed / Salama, Hosni / Alkheder, Ahmad / Taha, Mahmoud M

    International journal of surgery case reports

    2024  Volume 115, Page(s) 109266

    Abstract: Introduction: Schwannoma, a benign nerve sheath tumor originating from Schwann cells, can migrate within the spine due to various factors, impacting surgical planning. Unforeseen movement complicates treatment, and it is considered a very rare tumor.: ...

    Abstract Introduction: Schwannoma, a benign nerve sheath tumor originating from Schwann cells, can migrate within the spine due to various factors, impacting surgical planning. Unforeseen movement complicates treatment, and it is considered a very rare tumor.
    Case presentation: A 24-year-old woman complained of persistent back pain and was examined at a neurosurgery clinic. Initial MRI found a spinal lesion that later moved, leading to two surgeries. The diagnosis was a Schwannoma, confirmed by examining the tissue under a microscope, showing characteristic features of a Schwannoma, specifically Antoni type A with recent hemorrhage.
    Discussion: Schwannoma, a rare nerve cell tumor, often migrates within the spine due to its lack of attachment within the dura. The tumor's movement can be triggered by various factors like nerve root laxity, pressure changes, body positioning, or medical procedures. A case study discussed a woman with back pain; her tumor migrated between two MRI scans, showcasing a common migration pattern. Lower back pain commonly manifests as a primary symptom in most cases. Imaging techniques such as myelography and intraoperative ultrasound assist in locating and managing these mobile tumors, advocating for their utilization to minimize surgical complications.
    Conclusion: Reported a rare mobile thoracolumbar schwannoma from nerve sheath cells. Its mobility complicates surgery; precise imaging like intraoperative MRI and ultrasound are crucial for localization, preventing complications.
    Language English
    Publishing date 2024-01-13
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2024.109266
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  10. Article: Efficient training of spiking neural networks with temporally-truncated local backpropagation through time.

    Guo, Wenzhe / Fouda, Mohammed E / Eltawil, Ahmed M / Salama, Khaled Nabil

    Frontiers in neuroscience

    2023  Volume 17, Page(s) 1047008

    Abstract: Directly training spiking neural networks (SNNs) has remained challenging due to complex neural dynamics and intrinsic non-differentiability in firing functions. The well-known backpropagation through time (BPTT) algorithm proposed to train SNNs suffers ... ...

    Abstract Directly training spiking neural networks (SNNs) has remained challenging due to complex neural dynamics and intrinsic non-differentiability in firing functions. The well-known backpropagation through time (BPTT) algorithm proposed to train SNNs suffers from large memory footprint and prohibits backward and update unlocking, making it impossible to exploit the potential of locally-supervised training methods. This work proposes an efficient and direct training algorithm for SNNs that integrates a locally-supervised training method with a temporally-truncated BPTT algorithm. The proposed algorithm explores both temporal and spatial locality in BPTT and contributes to significant reduction in computational cost including GPU memory utilization, main memory access and arithmetic operations. We thoroughly explore the design space concerning temporal truncation length and local training block size and benchmark their impact on classification accuracy of different networks running different types of tasks. The results reveal that temporal truncation has a negative effect on the accuracy of classifying frame-based datasets, but leads to improvement in accuracy on event-based datasets. In spite of resulting information loss, local training is capable of alleviating overfitting. The combined effect of temporal truncation and local training can lead to the slowdown of accuracy drop and even improvement in accuracy. In addition, training deep SNNs' models such as AlexNet classifying CIFAR10-DVS dataset leads to 7.26% increase in accuracy, 89.94% reduction in GPU memory, 10.79% reduction in memory access, and 99.64% reduction in MAC operations compared to the standard end-to-end BPTT. Thus, the proposed method has shown high potential to enable fast and energy-efficient on-chip training for real-time learning at the edge.
    Language English
    Publishing date 2023-04-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1047008
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