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  1. Article ; Online: Reassessing the transport properties of fluids: A symbolic regression approach.

    Angelis, Dimitrios / Sofos, Filippos / Karakasidis, Theodoros E

    Physical review. E

    2024  Volume 109, Issue 1-2, Page(s) 15105

    Abstract: The viscosity and thermal conductivity coefficients of the Lennard-Jones fluid are extracted through symbolic regression (SR) techniques from data derived from simulations at the atomic scale. This data-oriented approach provides closed form relations ... ...

    Abstract The viscosity and thermal conductivity coefficients of the Lennard-Jones fluid are extracted through symbolic regression (SR) techniques from data derived from simulations at the atomic scale. This data-oriented approach provides closed form relations that achieve fine accuracy when compared to well-established theoretical, empirical, or approximate equations, fully transparent, with small complexity and high interpretability. The novelty is further outlined by suggesting analytical expressions for estimating fluid transport properties across the whole phase space, from a dilute gas to a dense liquid, by considering only two macroscopic properties (density and temperature). In such expressions, the underlying physical mechanisms are reflected, while, at the same time, it can be a computationally efficient alternative to costly in time and size first principle and/or molecular dynamics simulations.
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.015105
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  2. Article ; Online: Acetaminophen and the developing brain: A critical review of the evidence.

    Angelis, Dimitrios / Chalak, Lina

    Early human development

    2021  Volume 159, Page(s) 105411

    MeSH term(s) Acetaminophen/adverse effects ; Brain ; Head ; Humans
    Chemical Substances Acetaminophen (362O9ITL9D)
    Language English
    Publishing date 2021-06-17
    Publishing country Ireland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 752532-1
    ISSN 1872-6232 ; 0378-3782
    ISSN (online) 1872-6232
    ISSN 0378-3782
    DOI 10.1016/j.earlhumdev.2021.105411
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1373: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article: Implementation of morbidity and mortality conference in a community hospital NICU and narrative review.

    Chan, Christina / Pazandak, Christine / Angelis, Dimitrios

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1321296

    Abstract: Background: The process of morbidity and mortality review (MMR) is recognized as an essential component of quality improvement, patient safety, attitudes towards patient safety, and continuing education. Despite the common use of MMR for all disciplines ...

    Abstract Background: The process of morbidity and mortality review (MMR) is recognized as an essential component of quality improvement, patient safety, attitudes towards patient safety, and continuing education. Despite the common use of MMR for all disciplines of medical care, recommendations have not been published regarding the implementation of MMR in a community hospital setting in the United States.
    Objectives: Review the literature on MMR conferences. Describe the implementation of an MMR conference in a community hospital neonatal intensive care unit (NICU).
    Conclusions: The establishment of a case overview method of MMR is feasible for a community hospital NICU. It increases staff and physician group awareness and education over common and complex mortality and morbidity etiologies, improves staff participation with unit management, links case presentation with open discussion and action items, and identifies opportunities for systemic changes to improve patient care.
    Language English
    Publishing date 2023-12-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1321296
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  4. Article ; Online: Artificial Intelligence in Physical Sciences: Symbolic Regression Trends and Perspectives.

    Angelis, Dimitrios / Sofos, Filippos / Karakasidis, Theodoros E

    Archives of computational methods in engineering : state of the art reviews

    2023  , Page(s) 1–21

    Abstract: Symbolic regression (SR) is a machine learning-based regression method based on genetic programming principles that integrates techniques and processes from heterogeneous scientific fields and is capable of providing analytical equations purely from data. ...

    Abstract Symbolic regression (SR) is a machine learning-based regression method based on genetic programming principles that integrates techniques and processes from heterogeneous scientific fields and is capable of providing analytical equations purely from data. This remarkable characteristic diminishes the need to incorporate prior knowledge about the investigated system. SR can spot profound and elucidate ambiguous relations that can be generalizable, applicable, explainable and span over most scientific, technological, economical, and social principles. In this review, current state of the art is documented, technical and physical characteristics of SR are presented, the available programming techniques are investigated, fields of application are explored, and future perspectives are discussed.
    Supplementary information: The online version contains supplementary material available at 10.1007/s11831-023-09922-z.
    Language English
    Publishing date 2023-04-19
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2276736-8
    ISSN 1886-1784 ; 1134-3060
    ISSN (online) 1886-1784
    ISSN 1134-3060
    DOI 10.1007/s11831-023-09922-z
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  5. Article ; Online: Hyperglycemia and prematurity: a narrative review.

    Angelis, Dimitrios / Jaleel, Mambarambath A / Brion, Luc P

    Pediatric research

    2023  Volume 94, Issue 3, Page(s) 892–903

    Abstract: Hyperglycemia is commonly encountered in extremely preterm newborns and physiologically can be attributed to immaturity in several biochemical pathways related to glucose metabolism. Although hyperglycemia is associated with a variety of adverse outcomes ...

    Abstract Hyperglycemia is commonly encountered in extremely preterm newborns and physiologically can be attributed to immaturity in several biochemical pathways related to glucose metabolism. Although hyperglycemia is associated with a variety of adverse outcomes frequently described in this population, evidence for causality is lacking. Variations in definitions and treatment approaches have further complicated the understanding and implications of hyperglycemia on the immediate and long-term effects in preterm newborns. In this review, we describe the relationship between hyperglycemia and organ development, outcomes, treatment options, and potential gaps in knowledge that need further research. IMPACT: Hyperglycemia is common and less well described than hypoglycemia in extremely preterm newborns. Hyperglycemia can be attributed to immaturity in several cellular pathways involved in glucose metabolism in this age group. Hyperglycemia has been shown to be associated with a variety of adverse outcomes frequently described in this population; however, evidence for causality is lacking. Variations in definitions and treatment approaches have complicated the understanding and the implications of hyperglycemia on the immediate and long-term effects outcomes. This review describes the relationship between hyperglycemia and organ development, outcomes, treatment options, and potential gaps in knowledge that need further research.
    MeSH term(s) Infant, Newborn ; Humans ; Infant, Premature ; Hyperglycemia/complications ; Hyperglycemia/therapy ; Causality ; Hypoglycemia/complications ; Glucose ; Blood Glucose/metabolism
    Chemical Substances Glucose (IY9XDZ35W2) ; Blood Glucose
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-023-02628-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 373: Show issues

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  6. Article ; Online: Echocardiography evaluation of neonatal vein of Galen aneurysmal malformation.

    Doctor, Pezad / Ramaciotti, Claudio / Angelis, Dimitrios / Cory, Melinda

    Cardiology in the young

    2023  Volume 34, Issue 4, Page(s) 759–764

    Abstract: Background: In neonatal vein of Galen aneurysmal malformation, vein of Galen aneurysmal malformation echocardiography remains the mainstay for early detection and explains various haemodynamic changes occurring due to a large systemic arterio-venous ... ...

    Abstract Background: In neonatal vein of Galen aneurysmal malformation, vein of Galen aneurysmal malformation echocardiography remains the mainstay for early detection and explains various haemodynamic changes occurring due to a large systemic arterio-venous shunt. However, there is limited evidence of echocardiography in risk stratifying neonatal vein of Galen aneurysmal malformation vein of Galen aneurysmal malformation. The objective of this study was to identify echocardiographic parameters that could be associated with major outcomes and guide timing of neuro-intervention.
    Methods: In this retrospective chart review, infants < 28 days of age with the diagnosis of vein of Galen aneurysmal malformation vein of Galen aneurysmal malformation were included. Demographic, clinical, and echocardiographic parameters were compared in neonates who survived or died with neonatal presentation. A risk algorithm model based on key echocardiographic parameters was developed to determine those who are at risk of early death.
    Results: Of the 19 neonates included, with median birth weight 3.1 kg (IQR 2.58-3.36), nine (47%) neonates died at median age of 5 days (IQR 4-17). All neonates showed retrograde diastolic flow at the level of descending aorta by colour Doppler on the first post-natal echocardiogram at median age of 2 days (IQR 1-5.5). An aortic antegrade-to-retrograde velocity time integral ratio of < 1.5 and supra-systemic pulmonary artery pressure had 100% positive predictive value of death (p = 0.029), whereas aortic antegrade-to-retrograde velocity time integral ratio of > 1.5 and sub-systemic pulmonary artery pressure had 100% positive predictive value of survival (p = 0.029).
    Conclusion: Combination of aorta antegrade-to-retrograde velocity time integral ratio and degree of pulmonary hypertension on the first post-natal echocardiogram may help stratify the severity of disease and guide optimal timing for neuro-intervention for neonatal vein of Galen aneurysmal malformation.
    MeSH term(s) Infant, Newborn ; Infant ; Humans ; Cerebral Veins/abnormalities ; Cerebral Veins/diagnostic imaging ; Retrospective Studies ; Echocardiography
    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951123003402
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4050: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article: Fluid Properties Extraction in Confined Nanochannels with Molecular Dynamics and Symbolic Regression Methods.

    Angelis, Dimitrios / Sofos, Filippos / Papastamatiou, Konstantinos / Karakasidis, Theodoros E

    Micromachines

    2023  Volume 14, Issue 7

    Abstract: In this paper, we propose an alternative road to calculate the transport coefficients of fluids and the slip length inside nano-conduits in a Poiseuille-like geometry. These are all computationally demanding properties that depend on dynamic, thermal, ... ...

    Abstract In this paper, we propose an alternative road to calculate the transport coefficients of fluids and the slip length inside nano-conduits in a Poiseuille-like geometry. These are all computationally demanding properties that depend on dynamic, thermal, and geometrical characteristics of the implied fluid and the wall material. By introducing the genetic programming-based method of symbolic regression, we are able to derive interpretable data-based mathematical expressions based on previous molecular dynamics simulation data. Emphasis is placed on the physical interpretability of the symbolic expressions. The outcome is a set of mathematical equations, with reduced complexity and increased accuracy, that adhere to existing domain knowledge and can be exploited in fluid property interpolation and extrapolation, bypassing timely simulations when possible.
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14071446
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  8. Article: The Anatomage Table: A Promising Alternative in Anatomy Education.

    Kavvadia, Eirini-Maria / Katsoula, Ioanna / Angelis, Stavros / Filippou, Dimitrios

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43047

    Abstract: Anatomy is one of medical and nursing education's most prominent and crucial keynotes. For ages, conventional lectures and the analysis of actual human corpses were employed as predominant teaching techniques. However, the sphere of healthcare pedagogy ... ...

    Abstract Anatomy is one of medical and nursing education's most prominent and crucial keynotes. For ages, conventional lectures and the analysis of actual human corpses were employed as predominant teaching techniques. However, the sphere of healthcare pedagogy has been greatly altered by the developing passion for technology over the past few years. Anatomage offers a life-size digital representation of the human body, allowing the visualization, manipulation, and virtual dissection of complex anatomical structures, using detailed 3D (three-dimensional) models. Academic institutions utilize Anatomage as a means to enhance and contemporize the acquisition of anatomy knowledge. This systematic review aims to present the educational role of Anatomage in anatomy and whether it can replace the use of cadaveric material in medical education entirely in the future.  A detailed search on PubMed, SCOPUS, Wiley Online Library, and Google Scholar databases was performed. The criteria for the selection were the English language and the year of publication between 2018 and 2023. We rejected publications that were irrelevant to the topic. Before applying the filters, we found 198 publications, from which 24 were finally chosen for the purpose of this review.  The results of this systematic review indicate that most students agree on the beneficial role of Anatomage in the thorough comprehension of anatomical knowledge, and they prefer it over traditional learning methods, such as the use of cadaveric material. Anatomage not only offers a deeper insight into the relations between inner formations, since it is a particularly easy-to-use and pleasant teaching tool, but also contributes to the improvement of learning outcomes in the classroom, which is proved by higher grades in the anatomy course. However, it can be an effective teaching method if it is used in addition to the classic method of cadaver training, rather than being the only educational practice.  Integrating the Anatomage Table (AT) into undergraduate courses is paramount to the comprehensive learning and application of human anatomy in students' future health careers. Learners who have utilized the table note it to be a beneficial and effective tool in preparing them to enter into the healthcare profession.
    Language English
    Publishing date 2023-08-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43047
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  9. Article ; Online: Part III. Neuronal biochemical effects of acetaminophen and neurodevelopmental outcomes: Friend or foe?

    Angelis, Dimitrios / León, Rachel L / Chalak, Lina

    Early human development

    2021  Volume 159, Page(s) 105408

    MeSH term(s) Acetaminophen/adverse effects ; Humans
    Chemical Substances Acetaminophen (362O9ITL9D)
    Language English
    Publishing date 2021-06-12
    Publishing country Ireland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 752532-1
    ISSN 1872-6232 ; 0378-3782
    ISSN (online) 1872-6232
    ISSN 0378-3782
    DOI 10.1016/j.earlhumdev.2021.105408
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1373: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: The Story Retold: The Kocher Manoeuvre.

    Livani, Anastasia / Angelis, Stavros / Skandalakis, Panagiotis N / Filippou, Dimitrios

    Cureus

    2022  Volume 14, Issue 9, Page(s) e29409

    Abstract: The Kocher manoeuvre is used for mobilization of the duodenum and head of the pancreas and bears the name of Theodor Kocher, who published it in 1903. We describe the embryology of the duodenum and pancreas, relating it to surgical anatomy applied during ...

    Abstract The Kocher manoeuvre is used for mobilization of the duodenum and head of the pancreas and bears the name of Theodor Kocher, who published it in 1903. We describe the embryology of the duodenum and pancreas, relating it to surgical anatomy applied during the procedure. Finally, we present the key points of the procedure, providing more insights into the anatomical structures that are mainly involved.
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29409
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