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  1. Article ; Online: Reply to M. Sorigue et al.

    MacManus, Michael / Fisher, Richard / McClure, Bev / Seymour, John F

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2018  Volume 37, Issue 3, Page(s) 257–258

    MeSH term(s) Humans ; Lymphoma, Follicular
    Language English
    Publishing date 2018-11-26
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2018.18.01309
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    Zs.A 1847: Show issues Location:
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    Zs.MO 650: Show issues

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  2. Article: Occurrence of Meloidogyne fallax in North America, and Molecular Characterization of M. fallax and M. minor from U.S. Golf Course Greens.

    Nischwitz, Claudia / Skantar, Andrea / Handoo, Zafar A / Hult, Maria N / Schmitt, Mark E / McClure, Michael A

    Plant disease

    2019  Volume 97, Issue 11, Page(s) 1424–1430

    Abstract: ... amplified region (SCAR) primers that were originally designed to be specific for M. fallax were found ... to cross-react with M. minor. A population from California was determined to be M. fallax based on juvenile tail ... Resolution of M. fallax and M. chitwoodi using Hsp90 was equivalent to species separation obtained with 28S ...

    Abstract Several species of root-knot nematodes (Meloidogyne spp.) are known to have significant presence on turfgrass in golf course greens, particularly in the western United States. Nematodes isolated from a golf course in King County, WA were identified as Meloidogyne minor based on analysis of the large ribosomal subunit (LSU 28S D2-D3 expansion segment), the internal transcribed spacers 1 and 2 (ITS rDNA), the intergenic spacer region 2 (IGS2), and the nuclear protein-coding gene Hsp90. Sequence-characterized amplified region (SCAR) primers that were originally designed to be specific for M. fallax were found to cross-react with M. minor. A population from California was determined to be M. fallax based on juvenile tail morphology and analysis of the ribosomal markers and Hsp90, comprising the first report of this species in North America. Using trees based on Hsp90 genomic alignments, the phylogenetic relationships of these populations and known root-knot nematode species were congruent with previous trees based on ribosomal genes. Resolution of M. fallax and M. chitwoodi using Hsp90 was equivalent to species separation obtained with 28S or 18S rDNA alignments. The strengths and weaknesses of ribosomal and Hsp90 markers, and the use of SCAR polymerase chain reaction as diagnostic tools are discussed.
    Language English
    Publishing date 2019-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-03-13-0263-RE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 2043: Show issues

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  3. Article ; Online: Remembrances of Walter M. Fitch.

    Hall, Barry G / Ayala, Francisco J / McClure, Marcella A

    Molecular biology and evolution

    2011  Volume 28, Issue 12, Page(s) 3405–3409

    MeSH term(s) Evolution, Molecular ; History, 20th Century ; History, 21st Century ; Molecular Biology/history ; Periodicals as Topic/history ; United States
    Language English
    Publishing date 2011-12
    Publishing country United States
    Document type Biography ; Editorial ; Historical Article ; Portraits
    ZDB-ID 998579-7
    ISSN 1537-1719 ; 0737-4038
    ISSN (online) 1537-1719
    ISSN 0737-4038
    DOI 10.1093/molbev/msr260
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    Zs.A 2137: Show issues Location:
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  4. Article ; Online: Integrin-α7 signaling regulates connexin 43, M-cadherin, and myoblast fusion.

    McClure, Michael J / Ramey, Allison N / Rashid, Mashaba / Boyan, Barbara D / Schwartz, Zvi

    American journal of physiology. Cell physiology

    2019  Volume 316, Issue 6, Page(s) C876–C887

    Abstract: ... connexin 43 and M-cadherin. Our results demonstrated that α7 silencing blocked expression of myogenic ... transmembrane protein 8c (Tmem8c), indicating that myoblast fusion was inhibited. Expression of α5 and M ... extracellular-signal regulated kinase 1/2 (ERK) in α7-silenced cells that correlated with upregulation of connexin 43 and M-cadherin ...

    Abstract Regenerative medicine treatments for severe skeletal muscle injuries are limited, resulting in persistent functional deficits. Clinical options include neglecting the wound with the expectation that fibrosis will develop or using an autologous muscle graft with minimal functional improvement. A regenerative matrix can be used, but muscle fiber development on these matrices remains a challenge in vivo. Here, we explored the fundamental mechanisms that mediate cell-substrate signaling and its effect on cell-cell communication during myoblast fusion and tube formation to improve outcomes following implantation of matrices used to stimulate muscle regeneration. We previously reported that integrin-α7 was increased on anisotropic biomaterials, suggesting a role for α7β1 signaling in myoblast communication via connexin 43 and M-cadherin. Our results demonstrated that α7 silencing blocked expression of myogenic differentiation factor 1 (Myod), myogenin (Myog), myogenic factor 6 (Myf6), myosin heavy chain type 1 (Myh1), and transmembrane protein 8c (Tmem8c), indicating that myoblast fusion was inhibited. Expression of α5 and M-cadherin decreased but β1 and connexin 43 increased. We examined protein production and observed reduced extracellular-signal regulated kinase 1/2 (ERK) in α7-silenced cells that correlated with upregulation of connexin 43 and M-cadherin, suggesting a compensatory pathway. These results indicate that α7 signaling plays a critical role in ex vivo fusion and implicates a relationship with connexin 43 and M-cadherin.
    MeSH term(s) Animals ; Antigens, CD/genetics ; Cadherins/metabolism ; Cell Communication/physiology ; Cells, Cultured ; Connexin 43/metabolism ; Integrin alpha Chains/deficiency ; Integrin alpha Chains/genetics ; Mice ; Mice, Inbred C57BL ; Myoblasts/metabolism ; Signal Transduction/physiology
    Chemical Substances Antigens, CD ; Cadherins ; Connexin 43 ; Integrin alpha Chains ; integrin alpha7 ; M-cadherin (142845-03-2)
    Language English
    Publishing date 2019-03-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00282.2018
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    Uc I Zs.89: Show issues Location:
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  5. Article ; Online: Re: Surgical Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: .: H. E. Foster, M. J. Barry, P. Dahm, M. C. Gandhi, S. A. Kaplan, T. S. Kohler, L. B. Lerner, D. J. Lightner, J. K. Parsons, C. G. Roehrborn, C. Welliver, T. J. Wilt and K. T. McVary J Urol 2018; 200: 612-619.

    Bagla, Sandeep / Piechowiak, Rachel / McClure, Timothy D / Isaacson, Ari

    The Journal of urology

    2019  Volume 201, Issue 2, Page(s) 400–403

    MeSH term(s) Humans ; Lower Urinary Tract Symptoms ; Male ; Prostatic Hyperplasia
    Language English
    Publishing date 2019-01-02
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2018.09.058
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    Ui VI Zs.91: Show issues Location:
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    Zs.MO 331: Show issues

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  6. Article: Sterol Composition and Ecdysteroid Content of Eggs of the Root-knot Nematodes Meloidogyne incognita and M. arenaria.

    Chitwood, D J / McClure, M A / Feldlaufer, M F / Lusby, W R / Oliver, T E

    Journal of nematology

    2009  Volume 19, Issue 3, Page(s) 352–360

    Abstract: ... and M. arenaria race 1 were isolated and identified by gas-liquid chromatography-mass spectrometry ...

    Abstract Free and esterified sterols of eggs of the root-knot nematodes Meloidogyne incognita races 2 and 3 and M. arenaria race 1 were isolated and identified by gas-liquid chromatography-mass spectrometry. The major sterols of eggs of each race were 24-ethylcholesterol (33.4-38.8% of total sterol), 24-ethylcholestanol (18.3-25.3%), 24-methylcholesterol (8.6-11.7%), 24-methylcholestanol (7.7-12.5%), and cholesterol (4.6-11.6%). Consequently, the major metabolic transformation performed by Meloidogyne females or eggs upon host sterols appeared to be saturation of the sterol nucleus. The free and esterified sterols of the same race did not differ appreciably, except for a slight enrichment of the steryl esters in cholesterol. Although the sterol composition of Meloidogyne eggs differed from that of other life stages of other genera of plant-parasitic nematodes, the three Meloidogyne races could not be distinguished from each other by their egg sterols. Ecdysteroids, compounds with hormonal function in insects, were not detected by radioimmunoassay in the Meloidogyne eggs either as free ecdysteroids or as polar conjugates.
    Language English
    Publishing date 2009-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410426-2
    ISSN 0022-300X
    ISSN 0022-300X
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    Z 2645: Show issues

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  7. Article ; Online: Immune anticipation of mating in Drosophila: Turandot M promotes immunity against sexually transmitted fungal infections.

    Zhong, Weihao / McClure, Colin D / Evans, Cara R / Mlynski, David T / Immonen, Elina / Ritchie, Michael G / Priest, Nicholas K

    Proceedings. Biological sciences

    2013  Volume 280, Issue 1773, Page(s) 20132018

    Abstract: ... of immune and stress response genes, Turandot M and Turandot C (TotM and TotC), when they hear male ...

    Abstract Although it is well known that mating increases the risk of infection, we do not know how females mitigate the fitness costs of sexually transmitted infections (STIs). It has recently been shown that female fruitflies, Drosophila melanogaster, specifically upregulate two members of the Turandot family of immune and stress response genes, Turandot M and Turandot C (TotM and TotC), when they hear male courtship song. Here, we use the Gal4/UAS RNAi gene knockdown system to test whether the expression of these genes provides fitness benefits for females infected with the entomopathogenic fungus, Metarhizium robertsii under sexual transmission. As a control, we also examined the immunity conferred by Dorsal-related immunity factor (Dif), a central component of the Toll signalling pathway thought to provide immunity against fungal infections. We show that TotM, but not TotC or Dif, provides survival benefits to females following STIs, but not after direct topical infections. We also show that though the expression of TotM provides fecundity benefits for healthy females, it comes at a cost to their survival, which helps to explain why TotM is not constitutively expressed. Together, these results show that the anticipatory expression of TotM promotes specific immunity against fungal STIs and suggest that immune anticipation is more common than currently appreciated.
    MeSH term(s) Animals ; Disease Resistance ; Drosophila Proteins/antagonists & inhibitors ; Drosophila Proteins/immunology ; Drosophila Proteins/physiology ; Drosophila melanogaster/immunology ; Drosophila melanogaster/microbiology ; Drosophila melanogaster/physiology ; Female ; Fertility ; Gene Expression Regulation ; Heat-Shock Proteins/antagonists & inhibitors ; Heat-Shock Proteins/immunology ; Heat-Shock Proteins/physiology ; Male ; Metarhizium/immunology ; RNA Interference ; Sexual Behavior, Animal ; Signal Transduction
    Chemical Substances Drosophila Proteins ; Heat-Shock Proteins ; TotM protein, Drosophila
    Language English
    Publishing date 2013-10-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2013.2018
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    Zs.A 1364: Show issues Location:
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  8. Article: Structural ( n, m) determination of isolated single-wall carbon nanotubes by resonant Raman scattering.

    Jorio, A / Saito, R / Hafner, J H / Lieber, C M / Hunter, M / McClure, T / Dresselhaus, G / Dresselhaus, M S

    Physical review letters

    2001  Volume 86, Issue 6, Page(s) 1118–1121

    Abstract: ... dimensional systems, such as carbon nanotubes. Resonant confocal micro-Raman spectroscopy of an (n,m ...

    Abstract We show that the Raman scattering technique can give complete structural information for one-dimensional systems, such as carbon nanotubes. Resonant confocal micro-Raman spectroscopy of an (n,m) individual single-wall nanotube makes it possible to assign its chirality uniquely by measuring one radial breathing mode frequency omega(RBM) and using the theory of resonant transitions. A unique chirality assignment can be made for both metallic and semiconducting nanotubes of diameter d(t), using the parameters gamma(0) = 2.9 eV and omega(RBM) = 248/d(t). For example, the strong RBM intensity observed at 156 cm(-1) for 785 nm laser excitation is assigned to the (13,10) metallic chiral nanotube on a Si/SiO2 surface.
    Language English
    Publishing date 2001-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.86.1118
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    Z 4' 58/153: Show issues

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  9. Article: Performance of two commercially available sequence-based HIV-1 genotyping systems for the detection of drug resistance against HIV type 1 group M subtypes.

    Beddows, Simon / Galpin, Sarah / Kazmi, Shamim H / Ashraf, Ambreen / Johargy, Ayman / Frater, Alexander J / White, Natalie / Braganza, Ruth / Clarke, John / McClure, Myra / Weber, Jonathan N

    Journal of medical virology

    2003  Volume 70, Issue 3, Page(s) 337–342

    Abstract: ... Genotyping Kit (Visible Genetics, Toronto, Ontario) against a panel of 35 virus isolates from HIV-1 Group M ...

    Abstract The use of genotyping assays for the detection and evaluation of drug resistance mutations within the polymerase gene of human immunodeficiency virus type 1 (HIV-1) is becoming increasingly relevant in the clinical management of HIV-1 infection. However, genotypic resistance assays available currently have been optimised for genetic subtype B strains of the virus and many clinical centres are presented with strains from subtypes A, C, and D. In the present report, we compare the performance of two sequence-based commercially available kits, the ViroSeq Genotyping System (Applied Biosystems, Foster City, CA) and the TruGene HIV-1 Genotyping Kit (Visible Genetics, Toronto, Ontario) against a panel of 35 virus isolates from HIV-1 Group M (subtypes A-J). Full-length consensus sequences were generated by the ViroSeq genotyping system for 26 of 31 (83.8%) of the isolates tested, in contrast to the TruGene genotyping system, which generated 16 of 30 (53%) usable sequences overall. Overall, subtype B isolates were sequenced with a greater degree of success than non-subtype B isolates. Discrepancies were found between the consensus sequences reported by each system for each sample (mean difference 1.0%; range 0.0-3.2%), but these appeared to be random and did not affect interpretation of the major resistance codons. In addition, both systems were able to amplify template RNA from low copy viral load plasma samples (10(2)-10(3) RNA copies/ml) taken from a random selection of patient samples encompassing subtypes A-C. While the availability of these genotyping systems should facilitate studies of HIV-1 drug resistance in countries in which these subtypes are prevalent, the performance against subtypes other than B needs to be improved.
    MeSH term(s) Consensus Sequence ; Drug Resistance, Viral/genetics ; Genotype ; HIV-1/classification ; HIV-1/genetics ; Humans ; Phylogeny ; Polymerase Chain Reaction ; Reagent Kits, Diagnostic
    Chemical Substances Reagent Kits, Diagnostic
    Language English
    Publishing date 2003-07
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.10401
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    Zs.A 1320: Show issues Location:
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  10. Article: In vitro inhibition of growth of M. tuberculosis by certain 11-oxygenated steroids.

    HENNES, A R / MUCHMORE, H G / McCLURE, H G / HAMMARSTEN, J F

    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

    2003  Volume 101, Issue 1, Page(s) 145–147

    MeSH term(s) Adrenal Cortex Hormones/pharmacology ; Cell Respiration ; Hydrocortisone/pharmacology ; In Vitro Techniques ; Mycobacterium tuberculosis/drug effects ; Tuberculosis
    Chemical Substances Adrenal Cortex Hormones ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2003-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.3181/00379727-101-24861
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