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  1. Article ; Online: Clinical Applications of Ultrasonic Enhancing Agents in Echocardiography: 2018 American Society of Echocardiography Guidelines Update.

    Porter, Thomas R / Mulvagh, Sharon L / Abdelmoneim, Sahar S / Becher, Harald / Belcik, J Todd / Bierig, Michelle / Choy, Jonathan / Gaibazzi, Nicola / Gillam, Linda D / Janardhanan, Rajesh / Kutty, Shelby / Leong-Poi, Howard / Lindner, Jonathan R / Main, Michael L / Mathias, Wilson / Park, Margaret M / Senior, Roxy / Villanueva, Flordeliza

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2018  Volume 31, Issue 3, Page(s) 241–274

    MeSH term(s) Cardiovascular Diseases/diagnostic imaging ; Contrast Media/pharmacology ; Echocardiography/standards ; Humans ; Practice Guidelines as Topic ; Societies, Medical ; United States
    Chemical Substances Contrast Media
    Language English
    Publishing date 2018-03-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2017.11.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: American Society of Echocardiography minimum standards for the cardiac sonographer: a position paper.

    Bierig, S Michelle / Ehler, Donna / Knoll, Margaret L / Waggoner, Alan D

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2006  Volume 19, Issue 5, Page(s) 471–474

    MeSH term(s) Credentialing/standards ; Echocardiography/standards ; Practice Guidelines as Topic ; Practice Patterns, Physicians'/standards ; Professional Competence ; Quality Assurance, Health Care/standards ; Societies, Medical/standards ; United States
    Language English
    Publishing date 2006-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2006.03.032
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  3. Article: Efficacy of atropine as a chronotropic agent in heart transplant patients undergoing dobutamine stress echocardiography.

    Kociolek, Larry K / Bierig, S Michelle / Herrmann, Steven C / Labovitz, Arthur J

    Echocardiography (Mount Kisco, N.Y.)

    2006  Volume 23, Issue 5, Page(s) 383–387

    Abstract: Background: After heart transplant (HTX), the heart is completely denervated. While sympathetic reinnervation is likely to occur, there is conflicting evidence regarding parasympathetic reinnervation. Accordingly, it is unclear if atropine is ... ...

    Abstract Background: After heart transplant (HTX), the heart is completely denervated. While sympathetic reinnervation is likely to occur, there is conflicting evidence regarding parasympathetic reinnervation. Accordingly, it is unclear if atropine is efficacious as a chronotropic agent in HTX patients undergoing dobutamine stress echocardiography (DSE), since cholinergic cardiac stimulation is required for atropine to exert its effect. The purpose of this study was to demonstrate that atropine can sufficiently increase the heart rate (HR) in HTX patients undergoing DSE.
    Methods: A retrospective review was performed on 68 HTX patients who underwent DSE as part of their routine annual HTX follow-ups. Dobutamine was administered in the standard fashion of 10, 20, 30, 40, 50 mcg/kg per minute with blood pressure and electrocardiographic monitoring. If target HR was not attained, atropine was administered to aid in achieving 85% of maximum age-predicted HR.
    Results: Mean patient age was 58 +/- 10 years. Mean period since transplant was 9 +/- 4 years. Forty-seven (69%) patients received dobutamine only, and 21 (31%) required additional atropine to reach target HR. Of the 21 patients who received atropine, 10 (48%) reached target HR. Neither time from transplant, age, gender, resting HR, medications, nor atherosclerotic risk factors predicted responsiveness to atropine. Those responding to dobutamine had a significantly greater resting HR than those receiving additional atropine.
    Conclusions: The adjunctive use of atropine in HTX patients during DSE aids in reaching 85% of maximum predicted HR in some patients. Furthermore, resting HR may predict the additional need of atropine during DSE.
    MeSH term(s) Adult ; Aged ; Analysis of Variance ; Anti-Arrhythmia Agents ; Atropine ; Cardiotonic Agents/administration & dosage ; Dobutamine/administration & dosage ; Echocardiography, Stress/methods ; Female ; Heart Diseases/diagnostic imaging ; Heart Diseases/physiopathology ; Heart Diseases/surgery ; Heart Rate/drug effects ; Heart Transplantation ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Research Design ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Anti-Arrhythmia Agents ; Cardiotonic Agents ; Dobutamine (3S12J47372) ; Atropine (7C0697DR9I)
    Language English
    Publishing date 2006-05
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 843645-9
    ISSN 1540-8175 ; 0742-2822
    ISSN (online) 1540-8175
    ISSN 0742-2822
    DOI 10.1111/j.1540-8175.2006.00223.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparison of myocardial contrast echocardiography derived myocardial perfusion reserve with invasive determination of coronary flow reserve.

    Bierig, S Michelle / Mikolajczak, Peter / Herrmann, Steven C / Elmore, Nicole / Kern, Morton / Labovitz, Arthur J

    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology

    2009  Volume 10, Issue 2, Page(s) 250–255

    Abstract: Aims: Invasive measurements of coronary flow reserve (CFR) by Doppler flow wire are an established method for determining coronary blood flow physiology. Myocardial contrast echocardiography (MCE) is a potential non-invasive method for quantifying ... ...

    Abstract Aims: Invasive measurements of coronary flow reserve (CFR) by Doppler flow wire are an established method for determining coronary blood flow physiology. Myocardial contrast echocardiography (MCE) is a potential non-invasive method for quantifying myocardial blood flow (MBF). However, few studies have compared MCE-derived myocardial perfusion reserve (MPR) with Doppler flow wire-derived CFR, measured simultaneously in human subjects. This study aimed to correlate MCE-derived MPR with Doppler flow wire-derived CFR.
    Methods and results: Ten patients with at least two angiographically normal coronary arteries underwent simultaneous invasive Doppler flow wire measurements and MCE imaging at rest and at peak hyperaemia. Hyperaemia was induced by intravenous adenosine infusion. Doppler-derived CFR was calculated as the ratio of hyperaemic to baseline average peak red blood cell velocity. MPR was calculated as the hyperaemic to baseline ratio of the following parameters: myocardial blood volume (MBV), myocardial microbubble velocity (MMV), and MBF. MCE was performed using real-time and triggered imaging with contrast infused intravenously by bolus and continuous methods. Regardless of whether the contrast was infused by bolus or continuous methods, Doppler flow wire-derived CFR had a stronger correlation with MPR derived by MBV (r=0.8, P=0.05) than with MPR derived by microbubble velocity (r=0.3, P>0.05) or MBF (r=0.4, P>0.05). Real-time imaging with continuous infusion provided better correlation with CFR than triggered imaging methods or bolus administration.
    Conclusion: Myocardial perfusion reserve derived by real-time infusion MBV measurements correlates with Doppler flow wire-derived CFR. Therefore, MPR may be a potential surrogate for Doppler flow wire-derived CFR in patients with angiographically normal coronary arteries.
    MeSH term(s) Adult ; Contrast Media ; Coronary Angiography ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/pathology ; Female ; Fractional Flow Reserve, Myocardial ; Humans ; Male ; Middle Aged ; Myocardial Reperfusion ; Myocardium/pathology ; Statistics as Topic ; Stroke Volume ; Systole ; Ultrasonography ; Ventricular Function, Left
    Chemical Substances Contrast Media
    Language English
    Publishing date 2009-03
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2021408-X
    ISSN 1532-2114 ; 1525-2167
    ISSN (online) 1532-2114
    ISSN 1525-2167
    DOI 10.1093/ejechocard/jen217
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  5. Article: The research grant process: a reference guide for cardiovascular sonographers.

    Bierig, S Michelle / Coon, Patrick / Korcarz, Claudia E / Waggoner, Alan D

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2005  Volume 18, Issue 3, Page(s) 264–267

    Abstract: Opportunities for sonographer-initiated research have increased during the past decade. Although research has traditionally been viewed as a nonclinical activity, funding is available for clinical problems. This article aims to increase sonographer ... ...

    Abstract Opportunities for sonographer-initiated research have increased during the past decade. Although research has traditionally been viewed as a nonclinical activity, funding is available for clinical problems. This article aims to increase sonographer awareness of this unique opportunity, encourage the submission of grant proposals, and enhance the understanding of the grant writing process. This review discusses the procedures involved in planning a research project while describing the structure of the research grant proposal including specific aims, background, preliminary studies, methods, potential limitations, significance, budget, and references.
    MeSH term(s) Echocardiography ; Financing, Organized ; Information Services ; Research Design ; Research Support as Topic ; United States ; Writing
    Language English
    Publishing date 2005-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2004.11.014
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  6. Article ; Online: Clinical application of harmonic power Doppler imaging in the assessment of myocardial perfusion by contrast echocardiography.

    Belcik, J Todd / Bierig, S Michelle / Chadwell, Kimberly / Roberts, Brad

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2005  Volume 18, Issue 10, Page(s) 1083–1092

    Abstract: Myocardial contrast echocardiography has moved from the research laboratory to clinical echocardiography. As with any emerging technology, background information and understanding the process of image acquisition will help to integrate the technology ... ...

    Abstract Myocardial contrast echocardiography has moved from the research laboratory to clinical echocardiography. As with any emerging technology, background information and understanding the process of image acquisition will help to integrate the technology into everyday practice. Harmonic power Doppler imaging (HPDI) is a high-power, triggered imaging modality used to assess myocardial perfusion. Contrast agents used in echocardiography provide microvascular tracers that enable HPDI to accurately visualize myocardial blood flow. This article aims to provide direction in the clinical performance of myocardial contrast echocardiography by providing background in the theory and physics of HPDI and a guide to the technical acquisition of images and recognition of artifacts that arise during HPDI.
    MeSH term(s) Art ; Blood Flow Velocity ; Contrast Media ; Coronary Vessels/diagnostic imaging ; Echocardiography/methods ; Humans ; Image Enhancement/methods ; Image Interpretation, Computer-Assisted/methods ; Microbubbles ; Practice Guidelines as Topic ; Practice Patterns, Physicians' ; Ventricular Dysfunction, Left/diagnostic imaging
    Chemical Substances Contrast Media
    Language English
    Publishing date 2005-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2005.04.017
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  7. Article ; Online: American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with hypertrophic cardiomyopathy: Endorsed by the American Society of Nuclear Cardiology, Society for Cardiovascular Magnetic Resonance, and Society of Cardiovascular Computed Tomography.

    Nagueh, Sherif F / Bierig, S Michelle / Budoff, Matthew J / Desai, Milind / Dilsizian, Vasken / Eidem, Benjamin / Goldstein, Steven A / Hung, Judy / Maron, Martin S / Ommen, Steve R / Woo, Anna

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2011  Volume 24, Issue 5, Page(s) 473–498

    MeSH term(s) Cardiomyopathy, Hypertrophic/diagnosis ; Cardiomyopathy, Hypertrophic/diagnostic imaging ; Diastole ; Echocardiography/methods ; Echocardiography/standards ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/pathology ; Humans ; Magnetic Resonance Imaging, Cine/methods ; Magnetic Resonance Imaging, Cine/standards ; Societies, Medical ; Systole ; Tomography, Emission-Computed, Single-Photon ; Tomography, X-Ray Computed/standards ; United States
    Language English
    Publishing date 2011-05
    Publishing country United States
    Document type Journal Article ; Practice Guideline
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2011.03.006
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  8. Article: Tertiary care improves the chance for vaginal delivery in women with preeclampsia.

    Mostello, Dorothea / Droll, Deborah A / Bierig, S Michelle / Cruz-Flores, Salvador / Leet, Terry

    American journal of obstetrics and gynecology

    2003  Volume 189, Issue 3, Page(s) 824–829

    Abstract: Objective: The purpose of this study was to determine whether the level of hospital care affects cesarean delivery rates for women with preeclampsia.: Study design: We conducted a population-based cohort study using Missouri birth certificate data ... ...

    Abstract Objective: The purpose of this study was to determine whether the level of hospital care affects cesarean delivery rates for women with preeclampsia.
    Study design: We conducted a population-based cohort study using Missouri birth certificate data for 1993 through 1999. Logistic regression was used to analyze data from 13,646 nulliparous women with preeclampsia who were delivered of singleton live births.
    Results: After adjustment was made for gestational age and birth weight, the data showed that women with preeclampsia at primary and secondary hospitals were more likely to be delivered by cesarean delivery (odds ratio, 1.37; 95% CI, 1.24,1.51; and odds ratio, 1.16; 95% CI, 1.07,1.26, respectively) than at tertiary hospitals. For women who were delivered at >or=37 weeks of gestation, cesarean delivery rates were 38.0%, 33.7%, and 30.0% for primary, secondary, and tertiary hospitals, respectively. Dysfunctional labor, cephalopelvic disproportion, and fetal distress were more commonly noted at primary and secondary hospitals (P<.001).
    Conclusion: Levels of expertise and staffing at tertiary hospitals may allow greater attempts and success with vaginal delivery among women with preeclampsia compared with primary or secondary hospitals.
    MeSH term(s) Adolescent ; Adult ; Birth Weight ; Cesarean Section/statistics & numerical data ; Cohort Studies ; Delivery, Obstetric/methods ; Female ; Gestational Age ; Hospitals ; Humans ; Logistic Models ; Parity ; Patient Transfer ; Pre-Eclampsia/therapy ; Pregnancy
    Language English
    Publishing date 2003-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1067/s0002-9378(03)00713-0
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  9. Article: Serial changes in systolic and diastolic echocardiographic indices as predictors of outcome in patients with decreased left ventricular ejection fraction.

    Bierig, S Michelle / Ryan, Amanda / Ziaee, Ali / Kociolek, Larry / Simon, Jacqueline / Herrmann, Steven / Labovitz, Arthur J

    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology

    2007  Volume 8, Issue 5, Page(s) 369–374

    Abstract: Background: Echocardiographic estimation of left ventricular ejection fraction aids in predicting adverse outcomes in coronary artery disease. However, in patients with impaired left ventricular function, further risk stratification is difficult.: ... ...

    Abstract Background: Echocardiographic estimation of left ventricular ejection fraction aids in predicting adverse outcomes in coronary artery disease. However, in patients with impaired left ventricular function, further risk stratification is difficult.
    Methods: A 2 year retrospective review was performed to identify patients with ejection fraction < or=30%. Echocardiographic measures of systolic and diastolic function were independently performed offline. Outcome information, which included MI, stroke, or death, was obtained. The patient cohort identified those with follow-up having 1) a single echocardiogram and a subset 2) with an initial echocardiogram and a second echocardiogram at greater than one year follow-up.
    Results: This study included 110 patients, ages 20-94. Mean follow-up time was 29+/-9 months. Ejection fraction did not predict cardiovascular events. LV mass predicted of mortality (p=0.03). Diastolic indexes of mitral inflow E wave was a significant predictor of outcome (p=0.05). Impaired diastolic filling grade 2, 3, or 4 showed a 76% event rate. Decreases in ejection fraction at follow-up were seen in those who had an event, with an average decrease in ejection fraction of 17% versus those who lived with no event of 1%. Changes in mitral inflow E wave and changes in E/A ratio were both significant predictors of outcome.
    Conclusions: These data indicate that echocardiographic measures of both systolic and diastolic function aid in risk stratifying patients with decreased ejection fraction. The changed detected in serial echocardiographic information may be important in treatment and secondary prevention of future events.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Diastole/physiology ; Echocardiography ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Outcome Assessment (Health Care) ; Predictive Value of Tests ; Retrospective Studies ; Systole/physiology ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/physiopathology
    Language English
    Publishing date 2007-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2021408-X
    ISSN 1532-2114 ; 1525-2167
    ISSN (online) 1532-2114
    ISSN 1525-2167
    DOI 10.1016/j.euje.2006.07.007
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  10. Article ; Online: American Society of Echocardiography recommendations for quality echocardiography laboratory operations.

    Picard, Michael H / Adams, David / Bierig, S Michelle / Dent, John M / Douglas, Pamela S / Gillam, Linda D / Keller, Andrew M / Malenka, David J / Masoudi, Frederick A / McCulloch, Marti / Pellikka, Patricia A / Peters, Priscilla J / Stainback, Raymond F / Strachan, G Monet / Zoghbi, William A

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2011  Volume 24, Issue 1, Page(s) 1–10

    MeSH term(s) Cardiology/standards ; Cardiovascular Diseases/diagnosis ; Echocardiography/standards ; Humans ; Laboratories, Hospital/standards ; Practice Guidelines as Topic ; Quality Assurance, Health Care/standards ; United States
    Language English
    Publishing date 2011-01
    Publishing country United States
    Document type Journal Article ; Practice Guideline
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2010.11.006
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