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  1. Book ; Conference proceedings: Kansū-hōteishiki-to-fukuzatsu-kei

    Naito, Toshiki / Nakajima, Fumio

    kenkyū-shūkai-hōkokushū

    (Sūri-Kaiseki-Kenkyūsho-kōkyūroku ; 1445)

    2005  

    Title variant Functional equations and complex systems
    Event/congress Kongress (2005.03.17-19, Kyōto)
    Author's details Fumio Nakajima; Toshiki Naito
    Series title Sūri-Kaiseki-Kenkyūsho-kōkyūroku ; 1445
    Language Japanese ; English
    Size 3, 225 S, graph. Darst
    Publisher Kyoto University, Research Institute for Mathematical Sciences
    Publishing place Kyōto
    Document type Book ; Conference proceedings
    Note Text japan., teilw. engl ; Literaturangaben
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article: Moderate-to-Heavy Alcohol Consumption May Cause a Significant Decrease in Serum High-Density Lipoprotein Cholesterol in Middle-Aged Women: A Cohort Study of the National Database Study in the Kanto 7 Prefectures-4.

    Sekine, Airi / Nakajima, Kei

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55467

    Abstract: Aims Little is known about the association between habitual alcohol consumption and serum high-density lipoprotein cholesterol (HDL-C) in women. We aimed to investigate this association in middle-aged Japanese women in a community-based cohort study ... ...

    Abstract Aims Little is known about the association between habitual alcohol consumption and serum high-density lipoprotein cholesterol (HDL-C) in women. We aimed to investigate this association in middle-aged Japanese women in a community-based cohort study using conventional statistical analyses and explainable artificial intelligence (AI) analysis. Methods We retrospectively investigated the association between alcohol consumption and HDL-C after 10 years in 90,053 women aged 40-64 years whose drinking habits were generally consistent for 10 years. Results After 10 years, 11.3% and 17.9% of subjects had serum HDL-C decreased by ≥10 mg/dL and ≥10%, respectively. In unadjusted analysis, moderate-to-heavy alcohol consumption may both increase and decrease serum HDL-C levels after 10 years. After adjustment for potential confounding factors, moderate (23-45 g/day) and heavy (≥46 g/day) alcohol consumption were each significantly associated with decreases in HDL-C (OR (95% CI): 1.18 and 1.36 (1.11-1.26 and 1.21-1.53) for ≥10 mg/dL, 1.11 and 1.29 (1.05-1.17 and 1.17-1.43) for ≥10%), but not associated with an increase in HDL-C (0.96 and 0.98 (0.91-1.01 and 0.89-1.08) for ≥10 mg/dL, 0.97 and 0.96 (0.93-1.01 and 0.88-1.05) for ≥10%). Further analysis after adjustment for baseline serum HDL-C showed the same results. AI analysis showed that alcohol consumption was the 8th positive contributor to the decrease in HDL-C, following baseline high HDL-C (≥77 mg/dL), high low-density lipoprotein cholesterol (≥133 mg/dL), high body mass index (≥23.1 kg/m
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Serious Conditions in COVID-19 Accompanied With a Feature of Metabolic Syndrome.

    Nakajima, Kei

    Journal of clinical medicine research

    2020  Volume 12, Issue 5, Page(s) 273–275

    Keywords covid19
    Language English
    Publishing date 2020-05-08
    Publishing country Canada
    Document type Editorial
    ZDB-ID 2548987-2
    ISSN 1918-3011 ; 1918-3003
    ISSN (online) 1918-3011
    ISSN 1918-3003
    DOI 10.14740/jocmr4187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Relationship between non-restorative sleep and body weight in a general population: Results of NDB-K7Ps-Study-1.

    Nakajima, Kei / Sekine, Airi

    Obesity research & clinical practice

    2023  Volume 17, Issue 2, Page(s) 171–173

    MeSH term(s) Humans ; Body Weight ; Sleep ; Body Mass Index ; Thinness
    Language English
    Publishing date 2023-03-29
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2274031-4
    ISSN 1878-0318 ; 1871-403X
    ISSN (online) 1878-0318
    ISSN 1871-403X
    DOI 10.1016/j.orcp.2023.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Agreement in All-in-One Dataset between Diagnosis and Prescribed Medication for Common Cardiometabolic Diseases in the NDB-K7Ps.

    Sekine, Airi / Nakajima, Kei

    Epidemiologia (Basel, Switzerland)

    2023  Volume 4, Issue 4, Page(s) 370–381

    Abstract: The Japanese National Database (NDB), a useful data source for epidemiological studies, contains information on health checkups, disease diagnoses, and medications, which can be used when investigating common cardiometabolic diseases. However, before the ...

    Abstract The Japanese National Database (NDB), a useful data source for epidemiological studies, contains information on health checkups, disease diagnoses, and medications, which can be used when investigating common cardiometabolic diseases. However, before the initiation of an integrated analysis, we need to combine several pieces of information prepared separately into an all-in-one dataset (AIOD) and confirm the validation of the dataset for the study. In this study, we aimed to confirm the degree of agreement in data entries between diagnoses and prescribed medications and self-reported pharmacotherapy for common cardiometabolic diseases in newly assembled AIODs. The present study included 10,183,619 people who underwent health checkups from April 2018 to March 2019. Over 95% of patients prescribed antihypertensive and antidiabetic medications were diagnosed with each disease. For dyslipidemia, over 95% of patients prescribed medications were diagnosed with at least one of the following: dyslipidemia, hypercholesterolemia, or hyperlipidemia. Similarly, over 95% of patients prescribed medications for hyperuricemia were diagnosed with either hyperuricemia or gout. Additionally, over 90% of patients with self-reported medications for hypertension, diabetes, and dyslipidemia were diagnosed with each disease, although the proportions differed among age groups. Our study demonstrated high levels of agreement between diagnoses and prescribed medications for common cardiometabolic diseases and self-reported pharmacotherapy in our AIOD.
    Language English
    Publishing date 2023-10-02
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3986
    ISSN (online) 2673-3986
    DOI 10.3390/epidemiologia4040034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Agreement in All-in-One Dataset between Diagnosis and Prescribed Medication for Common Cardiometabolic Diseases in the NDB-K7Ps

    Airi Sekine / Kei Nakajima

    Epidemiologia, Vol 4, Iss 4, Pp 370-

    2023  Volume 381

    Abstract: The Japanese National Database (NDB), a useful data source for epidemiological studies, contains information on health checkups, disease diagnoses, and medications, which can be used when investigating common cardiometabolic diseases. However, before the ...

    Abstract The Japanese National Database (NDB), a useful data source for epidemiological studies, contains information on health checkups, disease diagnoses, and medications, which can be used when investigating common cardiometabolic diseases. However, before the initiation of an integrated analysis, we need to combine several pieces of information prepared separately into an all-in-one dataset (AIOD) and confirm the validation of the dataset for the study. In this study, we aimed to confirm the degree of agreement in data entries between diagnoses and prescribed medications and self-reported pharmacotherapy for common cardiometabolic diseases in newly assembled AIODs. The present study included 10,183,619 people who underwent health checkups from April 2018 to March 2019. Over 95% of patients prescribed antihypertensive and antidiabetic medications were diagnosed with each disease. For dyslipidemia, over 95% of patients prescribed medications were diagnosed with at least one of the following: dyslipidemia, hypercholesterolemia, or hyperlipidemia. Similarly, over 95% of patients prescribed medications for hyperuricemia were diagnosed with either hyperuricemia or gout. Additionally, over 90% of patients with self-reported medications for hypertension, diabetes, and dyslipidemia were diagnosed with each disease, although the proportions differed among age groups. Our study demonstrated high levels of agreement between diagnoses and prescribed medications for common cardiometabolic diseases and self-reported pharmacotherapy in our AIOD.
    Keywords national database ; diagnosis ; prescribed medication ; cardiometabolic diseases ; health checkups ; Internal medicine ; RC31-1245
    Subject code 610
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article ; Online: Clinicopathological evaluation of oral leukoplakia: a single-center study of 676 cases in Japan.

    Kokubun, Katsutoshi / Nakajima, Kei / Akashi, Yoshihiko / Yamamoto, Kei / Katakura, Akira / Matsuzaka, Kenichi

    Oral surgery, oral medicine, oral pathology and oral radiology

    2024  Volume 137, Issue 5, Page(s) 529–536

    Abstract: Objectives: To analyze the clinical and histopathological characteristics of oral leukoplakia (OL) in the Japanese population and investigate the prevalence and risk factors for epithelial dysplasia (ED) and carcinoma within lesions.: Study design: ... ...

    Abstract Objectives: To analyze the clinical and histopathological characteristics of oral leukoplakia (OL) in the Japanese population and investigate the prevalence and risk factors for epithelial dysplasia (ED) and carcinoma within lesions.
    Study design: Data, including age, sex, lesion site, and histopathological features, of 676 cases diagnosed with OL over the previous 10 years were analyzed. Dysplasia and carcinoma prevalence were determined.
    Results: In male patients, the most affected site was the gingiva (42.7%), whereas in females, it was the tongue (47.6%). Moreover, ED was more prevalent in males (41.9%), whereas epithelial hyperplasia was more common in females (44.7%). A significant difference was observed between affected sites with regard to the presence of dysplasia. The ED rates by site were 64.6% and 33.7% for the tongue and gingiva, respectively (P < 0.05). The squamous cell carcinoma rates by site were 23.4%, 5.4%, and 3.4% for the tongue, buccal mucosa, and gingiva, respectively (P < 0.05). Logistic regression analysis revealed a higher prevalence of dysplasia in males than it did in females and that the risk for both dysplasia and carcinoma was highest in the tongue.
    Conclusions: Dysplasia is common in OL cases, often showing carcinoma. Early biopsy and interventions are key in OL management.
    MeSH term(s) Humans ; Leukoplakia, Oral/pathology ; Leukoplakia, Oral/epidemiology ; Male ; Female ; Middle Aged ; Japan/epidemiology ; Aged ; Prevalence ; Risk Factors ; Adult ; Aged, 80 and over ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/epidemiology ; Precancerous Conditions/pathology ; Precancerous Conditions/epidemiology
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2650843-6
    ISSN 2212-4411 ; 2212-4403
    ISSN (online) 2212-4411
    ISSN 2212-4403
    DOI 10.1016/j.oooo.2024.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul III Zs.121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Evaluation of oral brush liquid-based cytology for oral squamous cell carcinoma: a comparative study of cytological and histological diagnoses at a single center.

    Kokubun, Katsutoshi / Nakajima, Kei / Yamamoto, Kei / Akashi, Yoshihiko / Matsuzaka, Kenichi

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 145

    Abstract: Purpose: Liquid-based cytology is highly useful in oral cytology. However, there are only few reports on the accuracy of this method. The current study aimed to compare oral liquid-based cytological and histological diagnoses and to evaluate items that ... ...

    Abstract Purpose: Liquid-based cytology is highly useful in oral cytology. However, there are only few reports on the accuracy of this method. The current study aimed to compare oral liquid-based cytological and histological diagnoses and to evaluate items that should be considered in oral cytological diagnosis for oral squamous cell carcinoma.
    Methods: We included 653 patients who underwent both oral cytological and histological examinations. Data on sex, specimen collection region, cytological and histological diagnoses, and histological images were reviewed.
    Results: The overall male-to-female ratio was 1:1.18. The tongue was the most common specimen collection region, followed by the gingiva and buccal mucosa. The most common cytological examination result was negative (66.8%), followed by doubtful (22.7%) and positive (10.3%). The sensitivity, specificity, positive predictive value, and negative predictive value of cytological diagnosis were 69%, 75%, 38%, and 92%, respectively. Approximately 8.3% of patients with a negative cytological diagnosis had a histological diagnosis of oral squamous cell carcinoma. Furthermore, 86.1% of histopathologic images of cytology-negative squamous cell carcinomas exhibited well-differentiated keratinocytes lacking atypia on the surface. The remaining patients developed recurrence, or they had low cell counts.
    Conclusion: Liquid-based cytology is useful in screening oral cancer. However, a cytological diagnosis of superficial-differentiated oral squamous cell carcinoma is occasionally inconsistent with the histological diagnosis. Therefore, histological and cytological examinations should be performed if tumor-like lesions are suspected clinically.
    MeSH term(s) Humans ; Male ; Female ; Carcinoma, Squamous Cell/pathology ; Mouth Neoplasms/pathology ; Squamous Cell Carcinoma of Head and Neck/pathology ; Cytodiagnosis/methods ; Head and Neck Neoplasms/pathology ; Sensitivity and Specificity
    Language English
    Publishing date 2023-03-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-02839-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Draft genome sequence data of Indian rhinoceros,

    Nabeshima, Kei / Nakajima, Nobuyoshi / Ogata, Mitsuaki / Onuma, Manabu

    Data in brief

    2022  Volume 41, Page(s) 107857

    Abstract: The Indian rhinoceros ( ...

    Abstract The Indian rhinoceros (
    Language English
    Publishing date 2022-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2022.107857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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