LIVIVO - Search results -

Search results

Result 1 - 10 of total 186

Search options

Article ; Online: COVID-19 vaccine-induced cutaneous lupus erythematosus.

Famularo, Giuseppe / Patti, Anna Linda / Macciomei, Maria Cristina

2023 Volume 29, Issue 5

MeSH term(s)	Humans ; COVID-19 Vaccines/adverse effects ; COVID-19/prevention & control ; Lupus Erythematosus, Cutaneous/chemically induced ; Skin ; Lupus Erythematosus, Systemic
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-10-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2026239-5
ISSN	1087-2108 ; 1087-2108
ISSN (online)	1087-2108
ISSN	1087-2108
DOI	10.5070/D329562421
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Corrigendum: Pubertal timing in children with Silver Russell syndrome compared to those born small for gestational age.

Patti, Giuseppa / Malerba, Federica / Calevo, Maria Grazia / Schiavone, Maurizio / Scaglione, Marco / Casalini, Emilio / Russo, Silvia / Fava, Daniela / Bassi, Marta / Napoli, Flavia / Allegri, Anna Elsa Maria / D'Annunzio, Giuseppe / Gastaldi, Roberto / Maghnie, Mohamad / Di Iorgi, Natascia

Frontiers in endocrinology

2023 Volume 14, Page(s) 1172736

Abstract: This corrects the article DOI: 10.3389/fendo.2022.975511.]. ...

Abstract	[This corrects the article DOI: 10.3389/fendo.2022.975511.].
Language	English
Publishing date	2023-03-15
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2023.1172736
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma.

Gonzalez-Aponte, Maria F / Damato, Anna R / Trebucq, Laura Lucía / Simon, Tatiana / Cárdenas-García, Sandra P / Cho, Kevin / Patti, Gary J / Golombek, Diego A / Chiesa, Juan José / Rubin, Joshua B / Herzog, Erik D

Journal of neuro-oncology

2024 Volume 166, Issue 3, Page(s) 419–430

Abstract: Background: Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite extensive research and clinical trials, median survival post-treatment remains at 15 months. Thus, all opportunities to optimize current treatments and improve ... ...

Abstract	Background: Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite extensive research and clinical trials, median survival post-treatment remains at 15 months. Thus, all opportunities to optimize current treatments and improve patient outcomes should be considered. A recent retrospective clinical study found that taking TMZ in the morning compared to the evening was associated with a 6-month increase in median survival in patients with MGMT-methylated GBM. Here, we hypothesized that TMZ efficacy depends on time-of-day and O Methods and results: In vitro recordings using real-time bioluminescence reporters revealed that GBM cells have intrinsic circadian rhythms in the expression of the core circadian clock genes Bmal1 and Per2, as well as in the DNA repair enzyme, MGMT. Independent measures of MGMT transcript levels and promoter methylation also showed daily rhythms intrinsic to GBM cells. These cells were more susceptible to TMZ when delivered at the daily peak of Bmal1 transcription. We found that in vivo morning administration of TMZ also decreased tumor size and increased body weight compared to evening drug delivery in mice bearing GBM xenografts. Finally, inhibition of MGMT activity with O Conclusion: We conclude that chemotherapy with TMZ can be dramatically enhanced by delivering at the daily maximum of tumor Bmal1 expression and minimum of MGMT activity and that scoring MGMT methylation status requires controlling for time of day of biopsy.
MeSH term(s)	Humans ; Animals ; Mice ; Glioblastoma/drug therapy ; Glioblastoma/genetics ; Glioblastoma/pathology ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Dacarbazine/therapeutic use ; Antineoplastic Agents, Alkylating/pharmacology ; Antineoplastic Agents, Alkylating/therapeutic use ; O(6)-Methylguanine-DNA Methyltransferase/genetics ; Retrospective Studies ; ARNTL Transcription Factors/genetics ; ARNTL Transcription Factors/metabolism ; Methylation ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/metabolism ; DNA Modification Methylases/genetics ; DNA Modification Methylases/metabolism ; DNA Methylation ; Brain Neoplasms/drug therapy ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
Chemical Substances	Temozolomide (YF1K15M17Y) ; Dacarbazine (7GR28W0FJI) ; Antineoplastic Agents, Alkylating ; O(6)-Methylguanine-DNA Methyltransferase (EC 2.1.1.63) ; ARNTL Transcription Factors ; DNA Repair Enzymes (EC 6.5.1.-) ; DNA Modification Methylases (EC 2.1.1.-) ; MGMT protein, human (EC 2.1.1.63) ; Tumor Suppressor Proteins
Language	English
Publishing date	2024-01-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	604875-4
ISSN	1573-7373 ; 0167-594X
ISSN (online)	1573-7373
ISSN	0167-594X
DOI	10.1007/s11060-023-04535-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1825: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Left Atrial Strain to Predict Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting.

Pastore, Maria Concetta / Degiovanni, Anna / Grisafi, Leonardo / Renda, Giulia / Sozzani, Martina / Giordano, Andrea / Salvatici, Cosimo / Lorenz, Veronica / Pierfelice, Francesca / Cappelli, Clelia / De Donno, Federica / Focardi, Marta / Ricci, Fabrizio / Benedetto, Umberto / Gallina, Sabina / Cameli, Matteo / Patti, Giuseppe

Circulation. Cardiovascular imaging

2024 Volume 17, Issue 1, Page(s) e015969

Abstract: Background: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery being associated with poorer outcomes. Revealing before the operation of left atrial subtle structural/functional abnormalities may help to identify ... ...

Abstract	Background: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery being associated with poorer outcomes. Revealing before the operation of left atrial subtle structural/functional abnormalities may help to identify patients at increased risk of POAF. We investigated the role of left atrial strain parameters by preoperative speckle tracking echocardiography as independent predictors of POAF in patients undergoing coronary artery bypass graft. Methods: Consecutive patients undergoing isolated coronary artery bypass graft were prospectively enrolled at three Italian centers. All patients underwent transthoracic echocardiography before the operation. The occurrence of POAF up to discharge was monitored. Results: Overall, a total of 310 patients were included. POAF was demonstrated in 103 patients (33%). At receiver operating characteristic curve analysis, lower global peak atrial longitudinal strain (PALS) values significantly predicted the risk of POAF (area under the curve, 0.74; Conclusions: A presurgery global PALS <28% is a specific parameter to stratify patients at increased risk of POAF after coronary artery bypass graft. This assessment can be useful to identify patients at higher arrhythmic risk in whom perioperative preventive strategies and stricter monitoring aimed at early diagnosing and treating POAF may be applied.
MeSH term(s)	Humans ; Aged ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/etiology ; Heart Atria/diagnostic imaging ; Coronary Artery Bypass/adverse effects ; Echocardiography ; Atrial Appendage ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/epidemiology ; Risk Factors ; Retrospective Studies
Language	English
Publishing date	2024-01-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2435045-X
ISSN	1942-0080 ; 1941-9651
ISSN (online)	1942-0080
ISSN	1941-9651
DOI	10.1161/CIRCIMAGING.123.015969
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6743: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Usefulness of a multiparametric evaluation including global longitudinal strain for an early diagnosis of acute myocarditis.

Degiovanni, Anna / Pastore, Maria Concetta / Spinoni, Enrico Guido / Focardi, Marta / Cameli, Matteo / Patti, Giuseppe

The international journal of cardiovascular imaging

2021 Volume 37, Issue 11, Page(s) 3203–3211

Abstract: Cardiac magnetic resonance imaging (CMRI) represents the main imaging modality for diagnosing acute myocarditis. However, its limited availability could entail missing or delayed diagnosis. A reduction of left ventricular global longitudinal strain (LV ... ...

Abstract	Cardiac magnetic resonance imaging (CMRI) represents the main imaging modality for diagnosing acute myocarditis. However, its limited availability could entail missing or delayed diagnosis. A reduction of left ventricular global longitudinal strain (LV GLS) by speckle tracking echocardiography (STE) correlates with amount of oedema in acute myocarditis and here may be early detected. Aim was to evaluate the diagnostic and prognostic role of 3-layers LV GLS in patients with acute myocarditis. Out of 122 patients with suspected acute myocarditis, a total of 86 consecutive patients with CMRI-confirmed acute myocarditis admitted in two Italian institutions were retrospectively screened. Exclusion criteria were met in 29 patients because of poor acoustic window or missing data. A total of 57 patients were then included. Clinical characteristics, laboratory examinations, transthoracic echocardiography data and STE parameters were collected early after hospitalization. In the study population, mean age was 38.8 ± 15.6 years, the prevalence of male gender was 90%. On admission, 22 patients (39%) had fever (body temperature > 37.5 °), mean white blood cell (WBC) count was 10.9 ± 1.7/10^3 and overall LV ejection fraction was 50.1% ± 11.2. An epicardial LV GLS < 18% was present in 74% of patients, and a model including at least one of LV GLS < 18% (absolute value), fever and WBC > 10.0/10^3 was able to identify all patients with CMRI-diagnosed acute myocarditis. An epicardial LV GLS < 15.3% (absolute value) at baseline significantly predicted the lack of myocarditis resolution during follow-up (AUC 0.76, 95% CI 0.58-0.93, p = 0.02). A multiparametric model including epicardial LV GLS, fever and elevated WBC count on admission could be useful for early diagnosing an acute myocarditis, especially when CMRI is not promptly available. Baseline epicardial LV GLS may also identify patients with less-likely myocarditis resolution.
MeSH term(s)	Adult ; Early Diagnosis ; Echocardiography ; Humans ; Male ; Middle Aged ; Myocarditis/diagnostic imaging ; Predictive Value of Tests ; Retrospective Studies ; Ventricular Function, Left ; Young Adult
Language	English
Publishing date	2021-06-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-021-02299-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2104: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Circadian regulation of

Gonzalez-Aponte, Maria F / Damato, Anna R / Trebucq, Laura Lucía / Simon, Tatiana / Cárdenas-García, Sandra P / Cho, Kevin / Patti, Gary J / Golombek, Diego A / Chiesa, Juan José / Herzog, Erik D

bioRxiv : the preprint server for biology

2023

Abstract	Background: Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite extensive research and clinical trials, median survival post-treatment remains at 15 months. Thus, all opportunities to optimize current treatments and improve patient outcomes should be considered. A recent retrospective clinical study found that taking TMZ in the morning compared to the evening was associated with a 6-month increase in median survival in patients with Methods and results: In vitro Conclusion: We conclude that chemotherapy with TMZ can be dramatically enhanced by delivering at the daily maximum of tumor
Language	English
Publishing date	2023-09-17
Publishing country	United States
Document type	Preprint
DOI	10.1101/2023.09.13.557630
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Precocious Puberty Diagnoses Spike, COVID-19 Pandemic, and Body Mass Index: Findings From a 4-year Study.

Fava, Daniela / Pepino, Carlotta / Tosto, Valentina / Gastaldi, Roberto / Pepe, Alessia / Paoloni, Dalila / Strati, Marina Francesca / Angelelli, Alessia / Calandrino, Andrea / Tedesco, Caterina / Camia, Tiziana / Allegri, Anna Elsa Maria / Patti, Giuseppa / Casalini, Emilio / Bassi, Marta / Calevo, Maria Grazia / Napoli, Flavia / Maghnie, Mohamad

Journal of the Endocrine Society

2023 Volume 7, Issue 9, Page(s) bvad094

Abstract: Context: Since the COVID-19 outbreak, the number of girls with suspected precocious puberty has increased.: Objective: To compare the incidence of idiopathic central precocious puberty (ICPP) during COVID-19 with that of the previous 4 years.: ... ...

Abstract	Context: Since the COVID-19 outbreak, the number of girls with suspected precocious puberty has increased. Objective: To compare the incidence of idiopathic central precocious puberty (ICPP) during COVID-19 with that of the previous 4 years. Methods: Anthropometric, biochemical, and radiological parameters were collected between January 2016 and June 2021 from 133 girls who met the Rapidly Progressive ICPP criteria (RP-ICPP). Results: We found a higher incidence of RP-ICPP between March 2020 and June 2021 (group 2) compared with January 2016 through March 2020 (group 1) (53.5% vs 41.1%); 2021 showed the highest annual incidence ( Conclusions: A spike in new diagnoses of idiopathic (1.79-fold higher) and RP-CPP coincided with the COVID-19 pandemic. The incidence of RP-ICPP was 1.3-fold higher during COVID-19 with a trend toward an increase in body mass index SD score. The expanding use of digital devices and the reduction of daily physical activity represent possible risk factors.
Language	English
Publishing date	2023-08-03
Publishing country	United States
Document type	Journal Article
ISSN	2472-1972
ISSN (online)	2472-1972
DOI	10.1210/jendso/bvad094
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Reply by Casella et al. to letter regarding article, incidence of ventricular arrhythmias related to COVID infection and vaccination in patients with Brugada syndrome: Insights from a large Italian multicenter registry based on continuous rhythm monitoring.

Journal of cardiovascular electrophysiology

2023 Volume 34, Issue 8, Page(s) 1791–1792

MeSH term(s)	Humans ; Brugada Syndrome/diagnosis ; Brugada Syndrome/epidemiology ; Incidence ; COVID-19/epidemiology ; COVID-19/prevention & control ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/epidemiology ; Electrocardiography ; Registries ; Vaccination
Language	English
Publishing date	2023-07-02
Publishing country	United States
Document type	Multicenter Study ; Letter ; Comment
ZDB-ID	1025989-2
ISSN	1540-8167 ; 1045-3873
ISSN (online)	1540-8167
ISSN	1045-3873
DOI	10.1111/jce.15989
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2863: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Blood Lymphocyte Subsets and Proinflammatory Cytokine Profile in ROHHAD(NET) and non-ROHHAD(NET) Obese Individuals.

Fava, Daniela / Morandi, Fabio / Prigione, Ignazia / Angelelli, Alessia / Bocca, Paola / Pistorio, Angela / Volpi, Stefano / Patti, Giuseppa / Pepino, Carlotta / Casalini, Emilio / Allegri, Anna Elsa Maria / Di Iorgi, Natascia / d'Annunzio, Giuseppe / Napoli, Flavia / Maghnie, Mohamad

Journal of the Endocrine Society

2023 Volume 7, Issue 9, Page(s) bvad103

Abstract: Context: Rapid-onset obesity with central hypoventilation, hypothalamic dysfunction, and autonomic dysregulation with neural crest tumors (ROHHAD-NET) syndrome pathophysiology remains elusive. Acquired neuroimmunological dysfunction has been proposed as ...

Abstract	Context: Rapid-onset obesity with central hypoventilation, hypothalamic dysfunction, and autonomic dysregulation with neural crest tumors (ROHHAD-NET) syndrome pathophysiology remains elusive. Acquired neuroimmunological dysfunction has been proposed as a possible pathogenetic pathway. Objective: The aim of our study was to characterize lymphocyte subpopulations subsets in peripheral blood (PB) and to evaluate a panel of proinflammatory cytokines/chemokines in ROHHAD(NET) patients vs controls. Methods: We included 11 ROHHAD(NET) patients, 7 ROHHAD and 4 ROHHAD-NET, selected by clinical criteria. Controls were 11 simple obese children, matched for age and sex. Flow cytometric analysis and enzyme-linked immunosorbent assay were performed on PB and serum samples of the 2 groups. Results: Analysis revealed that T lymphocytes are significantly increased in ROHHAD(NET) patients ( Conclusion: Our findings contribute to support the hypothesis of immune dysregulation, which may underlie this complex, often fatal disease. Because ROHHAD(NET) syndrome is an ultra-rare disease, multicentric studies are needed to improve the effect of our data in the management of this condition.
Language	English
Publishing date	2023-08-03
Publishing country	United States
Document type	Journal Article
ISSN	2472-1972
ISSN (online)	2472-1972
DOI	10.1210/jendso/bvad103
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Signals from the deep-sea: Genetic structure, morphometric analysis, and ecological implications of Cyclothone braueri (Pisces, Gonostomatidae) early life stages in the Central Mediterranean Sea.

Torri, Marco / Pappalardo, Anna Maria / Ferrito, Venera / Giannì, Salvatore / Armeri, Grazia Maria / Patti, Carlo / Mangiaracina, Francesca / Biondo, Girolama / Di Natale, Marilena / Musco, Marianna / Masullo, Tiziana / Bennici, Carmelo / Russo, Stefania / Nicosia, Aldo / Tagliavia, Marcello / Mazzola, Antonio / Patti, Bernardo / Cuttitta, Angela

Marine environmental research

2021 Volume 169, Page(s) 105379

Abstract: Cyclothone braueri (Stomiiformes, Gonostomatidae) is a widely distributed fish inhabiting the mesopelagic zone of marine tropical and temperate waters. Constituting one of the largest biomasses of the ocean, C. braueri is a key element in most of the ... ...

Abstract	Cyclothone braueri (Stomiiformes, Gonostomatidae) is a widely distributed fish inhabiting the mesopelagic zone of marine tropical and temperate waters. Constituting one of the largest biomasses of the ocean, C. braueri is a key element in most of the ecological processes occurring in the twilight layer. We focused on the ecological processes linked to early life stages in relation to marine pelagic environmental drivers (temperature, salinity, food availability and geostrophic currents) considering different regions of the Central Mediterranean Sea. A multivariate morphometric analysis was carried out using six parameters with the aim of discerning different larval morphotypes, while a fragment of 367 bp representing the 12S ribosomal RNA gene was used to perform molecular analyses aimed at determining the intraspecific genetic variability. Analysis highlighted two geographically distinct morphotypes not genetically discernible and related to the different nutritional conditions due to spatial heterogeneities in terms of temperature and food availability. The body depth (BD) emerged as an appropriate morphometric parameter to detect the larval condition in this species. Molecular analysis highlighted a moderate genetic divergence in the fish population, showing the recurrence of two phylogroups not geographically separated.
MeSH term(s)	Animals ; Ciliophora ; Fishes ; Genetic Structures ; Larva/genetics ; Mediterranean Sea
Language	English
Publishing date	2021-06-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1502505-6
ISSN	1879-0291 ; 0141-1136
ISSN (online)	1879-0291
ISSN	0141-1136
DOI	10.1016/j.marenvres.2021.105379
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito