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  1. Article ; Online: Serum thyroid hormone profile in critically Ill children.

    Suvarna, Jyoti Chandrashekar / Fande, Chandrashekar N

    Indian journal of pediatrics

    2009  Volume 76, Issue 12, Page(s) 1217–1221

    Abstract: Objective: To study thyroid hormone profile in critically ill children and its correlation to disease severity and clinical outcome.: Methods: Total serum triiodothyronine (T3), thyroxine (T4) and TSH were estimated at admission and discharge from ... ...

    Abstract Objective: To study thyroid hormone profile in critically ill children and its correlation to disease severity and clinical outcome.
    Methods: Total serum triiodothyronine (T3), thyroxine (T4) and TSH were estimated at admission and discharge from PICU/ just before death.
    Results: Mean T3 levels in cases were significantly lower than controls and lower in patients who expired, both at admission and just prior to death. Mean T4 levels were lower in cases, and just prior to death. Mean TSH levels were not different in cases and controls; or in survived and expired cases. When both T3 and T4 are low, mortality risk increases 30 times. Serum T3, T4 and TSH values improved in patients who survived unlike in those who expired. Age, sex, duration of hospital stay, ventilation, inotropic support, and PICU stay did not show any correlation with patient outcome or thyroid hormone profile. PRISM score at 24 hours and T4 levels in the second sample were significant predictors of survival.
    Conclusion: T3 levels reflect the patient's clinical status, T4 levels can predict survival.
    MeSH term(s) Case-Control Studies ; Child ; Child, Preschool ; Critical Illness ; Euthyroid Sick Syndromes/blood ; Humans ; India ; Infant ; Intensive Care Units ; Logistic Models ; Prognosis ; Prospective Studies ; Survival Analysis ; Thyrotropin/blood ; Thyroxine/blood ; Triiodothyronine/blood
    Chemical Substances Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5) ; Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2009-11-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-009-0250-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 826: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Serum lipid profile: a predictor of clinical outcome in dengue infection.

    Suvarna, Jyoti Chandrashekar / Rane, Pankaj P

    Tropical medicine & international health : TM & IH

    2009  Volume 14, Issue 5, Page(s) 576–585

    Abstract: Objectives: To correlate serum lipoproteins levels with dengue severity, clinical outcome (patient survival), bleeding severity, capillary leakage, supportive care requirement and hospital stay duration.: Methods: Single centre, prospective study.: ...

    Abstract Objectives: To correlate serum lipoproteins levels with dengue severity, clinical outcome (patient survival), bleeding severity, capillary leakage, supportive care requirement and hospital stay duration.
    Methods: Single centre, prospective study.
    Setting: Tertiary care hospital.
    Subjects: 50 (1 month-18 years) dengue fever cases and 50 age and sex matched non-febrile controls. Methods: patients were classified (WHO criteria) as dengue fever (DF), dengue haemorrhagic fever (DHF), dengue shock syndrome (DSS). Bleeding score; serum triglyceride, cholesterol, HDL, LDL and VLDL was determined. Statistical analysis was done using Chi-squared test with continuity correction, Unpaired t-test, ANOVA with post hoc test, Binary logistic and multinomial regression.
    Results: 18 (36%) patients were DF, 19 (38%) DHF and 13 (26%) DSS. Lowest cholesterol, VLDL levels seen in DSS and highest in DF. Mean cholesterol level is significantly lower in expired patients and patients with third spacing. Severe bleeding significantly correlated with cholesterol level and hepatic dysfunction but not with platelet count or coagulopathy. Duration of intravenous fluid requirement and packed cell requirement negatively correlated with HDL and cholesterol levels. Fresh frozen plasma requirement negatively correlated with TG, HDL, VLDL and cholesterol levels. Platelet transfusion requirement and duration of hospital stay did not correlate with lipid levels. Intensive care and ventilator requirement negatively correlated with cholesterol level; inotrope requirement negatively correlated with HDL level. Ventilator requirement correlated negatively with TG levels also.
    Conclusions: Lipid profile changes accompany dengue infection, some of which may indicate severity and guide therapy.
    MeSH term(s) Adolescent ; Antibodies, Viral/blood ; Biomarkers/blood ; Child ; Child, Preschool ; Dengue/blood ; Dengue/epidemiology ; Female ; Humans ; India/epidemiology ; Infant ; Lipoproteins/blood ; Male ; Practice Guidelines as Topic ; Predictive Value of Tests ; Prospective Studies
    Chemical Substances Antibodies, Viral ; Biomarkers ; Lipoproteins
    Language English
    Publishing date 2009-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314080-2
    ISSN 1365-3156 ; 1360-2276
    ISSN (online) 1365-3156
    ISSN 1360-2276
    DOI 10.1111/j.1365-3156.2009.02261.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4415: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Serum lipid profile: a predictor of clinical outcome in dengue infection

    Suvarna, Jyoti Chandrashekar / Rane, Pankaj P

    Tropical medicine & international health TM & IH. 2009 May, v. 14, no. 5

    2009  

    Abstract: To correlate serum lipoproteins levels with dengue severity, clinical outcome (patient survival), bleeding severity, capillary leakage, supportive care requirement and hospital stay duration. Single centre, prospective study. Setting: Tertiary care ... ...

    Abstract To correlate serum lipoproteins levels with dengue severity, clinical outcome (patient survival), bleeding severity, capillary leakage, supportive care requirement and hospital stay duration. Single centre, prospective study. Setting: Tertiary care hospital. Subjects: 50 (1 month-18 years) dengue fever cases and 50 age and sex matched non-febrile controls. Methods: patients were classified (WHO criteria) as dengue fever (DF), dengue haemorrhagic fever (DHF), dengue shock syndrome (DSS). Bleeding score; serum triglyceride, cholesterol, HDL, LDL and VLDL was determined. Statistical analysis was done using Chi-squared test with continuity correction, Unpaired t-test, anova with post hoc test, Binary logistic and multinomial regression. 18 (36%) patients were DF, 19 (38%) DHF and 13 (26%) DSS. Lowest cholesterol, VLDL levels seen in DSS and highest in DF. Mean cholesterol level is significantly lower in expired patients and patients with third spacing. Severe bleeding significantly correlated with cholesterol level and hepatic dysfunction but not with platelet count or coagulopathy. Duration of intravenous fluid requirement and packed cell requirement negatively correlated with HDL and cholesterol levels. Fresh frozen plasma requirement negatively correlated with TG, HDL, VLDL and cholesterol levels. Platelet transfusion requirement and duration of hospital stay did not correlate with lipid levels. Intensive care and ventilator requirement negatively correlated with cholesterol level; inotrope requirement negatively correlated with HDL level. Ventilator requirement correlated negatively with TG levels also. Lipid profile changes accompany dengue infection, some of which may indicate severity and guide therapy.
    Keywords cholesterol ; lipoproteins ; triacylglycerols
    Language English
    Dates of publication 2009-05
    Size p. 576-585.
    Publisher Blackwell Publishing Ltd
    Publishing place Oxford, UK
    Document type Article
    ZDB-ID 1314080-2
    ISSN 1365-3156 ; 1360-2276
    ISSN (online) 1365-3156
    ISSN 1360-2276
    DOI 10.1111/j.1365-3156.2009.02261.x
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4415: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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