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  1. Article ; Online: Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota.

    Zhou, Guo-Feng / Jiang, Yue-Hua / Ma, Du-Fang / Wang, Yong-Cheng / Yang, Jin-Long / Chen, Ji-Ye / Chi, Chen-Yu / Han, Xiao-Wei / Li, Zhao-Yu / Li, Xiao

    BioMed research international

    2019  Volume 2019, Page(s) 9637479

    Abstract: ... Xiao-Qing-Long Tang (XQLT), a traditional herbal formula, has an anti-inflammatory effect and regulates ...

    Abstract Background: Changes in the gut microbiota are associated with cardiovascular disease progression. Xiao-Qing-Long Tang (XQLT), a traditional herbal formula, has an anti-inflammatory effect and regulates the steady state of the immune system, which is also associated with the progression of heart failure with preserved ejection faction (HFpEF). In this study, we investigated whether XQLT could contribute to prevent the development of HFpEF and whether the modulation of the gut microbiota by this herbal formula could be involved in such effect.
    Methods: The gut microbiota, SCFAs, the histology/function of the heart, and systolic blood pressure were examined to evaluate the effect of XQLT on the gut microbiota and the progression of HFpEF after oral administration of XQLT to model rats. Furthermore, we evaluated, through fecal microbiota transplantation experiments, whether the favorable effects of XQLT could be mediated by the gut microbiota.
    Results: Oral administration of XQLT contributed to the reduction of elevated blood pressure, inflammation, and compensatory hypertrophy, features that are associated with the progression of HFpEF. The gut microbiota composition, SCFA levels, and intestinal mucosal histology were improved after treatment with XQLT. Moreover, fecal transfer from XQLT-treated rats was sufficient to prevent the progression of HFpEF.
    Conclusions: These data suggested that XQLT prevented the development of HFpEF in model rats by regulating the composition of the gut microbiota.
    MeSH term(s) Administration, Oral ; Animals ; Cardiomegaly/drug therapy ; Cardiomegaly/metabolism ; Cardiomegaly/microbiology ; Cardiomegaly/physiopathology ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Fibrosis ; Gastrointestinal Microbiome/drug effects ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Heart Failure/microbiology ; Heart Failure/physiopathology ; Male ; Myocytes, Cardiac/metabolism ; Rats ; Rats, Inbred Dahl ; Stroke Volume/drug effects
    Chemical Substances Drugs, Chinese Herbal ; sho-seiryu-to
    Language English
    Publishing date 2019-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2019/9637479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota

    Guo-Feng Zhou / Yue-Hua Jiang / Du-Fang Ma / Yong-Cheng Wang / Jin-Long Yang / Ji-Ye Chen / Chen-Yu Chi / Xiao-wei Han / Zhao-Yu Li / Xiao Li

    BioMed Research International, Vol

    2019  Volume 2019

    Abstract: ... Xiao-Qing-Long Tang (XQLT), a traditional herbal formula, has an anti-inflammatory effect and regulates ...

    Abstract Background. Changes in the gut microbiota are associated with cardiovascular disease progression. Xiao-Qing-Long Tang (XQLT), a traditional herbal formula, has an anti-inflammatory effect and regulates the steady state of the immune system, which is also associated with the progression of heart failure with preserved ejection faction (HFpEF). In this study, we investigated whether XQLT could contribute to prevent the development of HFpEF and whether the modulation of the gut microbiota by this herbal formula could be involved in such effect. Methods. The gut microbiota, SCFAs, the histology/function of the heart, and systolic blood pressure were examined to evaluate the effect of XQLT on the gut microbiota and the progression of HFpEF after oral administration of XQLT to model rats. Furthermore, we evaluated, through fecal microbiota transplantation experiments, whether the favorable effects of XQLT could be mediated by the gut microbiota. Results. Oral administration of XQLT contributed to the reduction of elevated blood pressure, inflammation, and compensatory hypertrophy, features that are associated with the progression of HFpEF. The gut microbiota composition, SCFA levels, and intestinal mucosal histology were improved after treatment with XQLT. Moreover, fecal transfer from XQLT-treated rats was sufficient to prevent the progression of HFpEF. Conclusions. These data suggested that XQLT prevented the development of HFpEF in model rats by regulating the composition of the gut microbiota.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article ; Online: Analysis of drug-induced posterior reversible encephalopathy syndrome using the food and drug administration adverse drug events reporting system database.

    Lei, Cai-Lu / Gui, Xiao-Long / Wang, Lin-Yu / Guo, You-Jia / Li, Yan

    Expert opinion on drug safety

    2024  , Page(s) 1–10

    Abstract: Objective: In this retrospective pharmacovigilance study, we gathered data on drug-induced posterior reversible encephalopathy syndrome (PRES). Our goal was to identify the primary suspect drugs in PRES by analyzing the Food and Drug Administration ... ...

    Abstract Objective: In this retrospective pharmacovigilance study, we gathered data on drug-induced posterior reversible encephalopathy syndrome (PRES). Our goal was to identify the primary suspect drugs in PRES by analyzing the Food and Drug Administration Adverse Events Reporting System (FAERS) database.
    Methods: We identified and analyzed reports of PRES listed in the FAERS database between 2004 and 2021. Using the reporting odds ratio and 95% confidence interval, we evaluated the safety signals for each of the drugs associated with PRES.
    Results: We reviewed 11,077 reports of adverse events corresponding to PRES. The primary suspect drug categories were antineoplastics, immunosuppressants, and glucocorticoids. PRES was 24.77% more likely to occur in females than in males. Drug-induced PRES usually occurs in individuals with cancer, those who have undergone an organ/stem cell transplant, and those with autoimmune conditions.
    Conclusion: Our results show that the drugs most commonly suspected to cause PRES were antineoplastics, immunosuppressants, and glucocorticoids. Future studies are needed to illuminate the pathophysiological alterations that underlie PRES. In the meantime, prescribers and patients should be made aware of the potential risks of PRES associated with pharmaceutical therapy, and the summaries of product characteristics for individual drugs should be updated to include this information.
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088728-0
    ISSN 1744-764X ; 1474-0338
    ISSN (online) 1744-764X
    ISSN 1474-0338
    DOI 10.1080/14740338.2024.2327510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6096: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Exogenous Easily Extractable Glomalin-Related Soil Protein Stimulates Plant Growth by Regulating Tonoplast Intrinsic Protein Expression in Lemon.

    Guo, Xiao-Niu / Hao, Yong / Wu, Xiao-Long / Chen, Xin / Liu, Chun-Yan

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 16

    Abstract: Arbuscular mycorrhizal fungi (AMF) have the function of promoting water absorption for the host plant, whereas the role of easily extractable glomalin-related soil protein (GRSP), an N-linked glycoprotein secreted by AMF hyphae and spores, is unexplored ... ...

    Abstract Arbuscular mycorrhizal fungi (AMF) have the function of promoting water absorption for the host plant, whereas the role of easily extractable glomalin-related soil protein (GRSP), an N-linked glycoprotein secreted by AMF hyphae and spores, is unexplored for citrus plants. In this study, the effects on plant growth performance, root system characteristics, and leaf water status, along with the changes of mineral element content and relative expressions of tonoplast intrinsic protein (
    Language English
    Publishing date 2023-08-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12162955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Terpenoids from

    Zhou, Bo / Guo, Meng-Jia / Zhao, Xin-Man / Li, Xiao-Long / Liu, Shao-Huan / Shen, Xiang-Chun / Zhang, Nen-Ling

    Natural product research

    2024  , Page(s) 1–8

    Abstract: A new labdane diterpene ( ...

    Abstract A new labdane diterpene (
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2024.2346269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: High Dietary Folic Acid Supplementation Reduced the Composition of Fatty Acids and Amino Acids in Fortified Eggs.

    Yu, Ao-Chuan / Deng, Yu-Han / Long, Cheng / Sheng, Xi-Hui / Wang, Xiang-Guo / Xiao, Long-Fei / Lv, Xue-Ze / Chen, Xiang-Ning / Chen, Li / Qi, Xiao-Long

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 7

    Abstract: Aims: The study aimed to evaluate the effects of dietary folic acid (FA) on the production performance of laying hens, egg quality, and the nutritional differences between eggs fortified with FA and ordinary eggs.: Methods: A total of 288 26-week-old ...

    Abstract Aims: The study aimed to evaluate the effects of dietary folic acid (FA) on the production performance of laying hens, egg quality, and the nutritional differences between eggs fortified with FA and ordinary eggs.
    Methods: A total of 288 26-week-old Hy-Line Brown laying hens (initial body weights 1.65 ± 0.10 kg) with a similar weight and genetic background were used. A completely randomized design divided the birds into a control group and three treatment groups. Each group consisted of six replicates, with twelve chickens per replicate. Initially, all birds were fed a basal diet for 1 week. Subsequently, they were fed a basal diet supplemented with 0, 5, 10, or 15 mg/kg FA in a premix for a duration of 6 weeks.
    Results: Supplementation of FA could significantly (
    Conclusion: The findings suggest that the appropriate addition of FA can enhance the levels of MUFA and vitamin D in egg yolks, thereby improving their nutritional value. Excessive intake of FA can decrease the effectiveness of enriching FA in egg yolk and impact the enrichment of certain amino acids. The yolk of eggs produced by adding 10 mg/kg of FA to the feed contains the optimal amount of nutrients. This study informs consumers purchasing FA-fortified eggs.
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13071048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effects of dietary pretreated Chinese herbal medicine supplementation on production performance, egg quality, uterine histopathological changes, and antioxidant capacity in late-phase laying hens.

    Yu, Ao-Chuan / Wang, Min-An / Chen, Li / Long, Cheng / Guo, Yong / Sheng, Xi-Hui / Wang, Xiang-Guo / Xing, Kai / Xiao, Long-Fei / Ni, He-Min / Li, Jian-Tao / Qi, Xiao-Long

    Frontiers in physiology

    2023  Volume 14, Page(s) 1110301

    Abstract: Aims: ...

    Abstract Aims:
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1110301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Climate change impacts the distribution of

    Lin, Lin / Jiang, Xiao-Long / Guo, Kai-Qi / Byrne, Amy / Deng, Min

    Plant diversity

    2023  Volume 45, Issue 5, Page(s) 552–568

    Abstract: East Asian evergreen broadleaved forests (EBFLs) harbor high species richness, but these ecosystems are severely impacted by global climate change and deforestation. Conserving and managing EBLFs requires understanding dominant tree distribution dynamics. ...

    Abstract East Asian evergreen broadleaved forests (EBFLs) harbor high species richness, but these ecosystems are severely impacted by global climate change and deforestation. Conserving and managing EBLFs requires understanding dominant tree distribution dynamics. In this study, we used 29 species in
    Language English
    Publishing date 2023-04-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 2873411-7
    ISSN 2468-2659 ; 2095-0845
    ISSN (online) 2468-2659
    ISSN 2095-0845
    DOI 10.1016/j.pld.2023.03.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Physiological and Transcriptional Analyses Provide Insight into Maintaining Ion Homeostasis of Sweet Sorghum under Salt Stress.

    Guo, Huan / Nie, Chun-Ya / Li, Zhen / Kang, Jie / Wang, Xiao-Long / Cui, Yan-Nong

    International journal of molecular sciences

    2023  Volume 24, Issue 13

    Abstract: Sweet sorghum is an important bioenergy grass and valuable forage with a strong adaptability to saline environments. However, little is known about the mechanisms of sweet sorghum coping with ion toxicity under salt stresses. Here, we first evaluated the ...

    Abstract Sweet sorghum is an important bioenergy grass and valuable forage with a strong adaptability to saline environments. However, little is known about the mechanisms of sweet sorghum coping with ion toxicity under salt stresses. Here, we first evaluated the salt tolerance of a sweet sorghum cultivar "Lvjuren" and determined its ion accumulation traits under NaCl treatments; then, we explored key genes involved in Na
    MeSH term(s) Sorghum/genetics ; Sodium Chloride/pharmacology ; Salt Stress ; Salt Tolerance/genetics ; Homeostasis ; Stress, Physiological/genetics
    Chemical Substances Sodium Chloride (451W47IQ8X)
    Language English
    Publishing date 2023-07-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241311045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Potential antidepressant effects of Traditional Chinese botanical drug formula Chaihu-Shugan-San and its active ingredients.

    Guo, Ziyi / Long, Tianjian / Yao, Jianping / Li, Yamin / Xiao, Lu / Chen, Min

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1337876

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1337876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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