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  1. Article ; Online: Insights in intestinal immune tolerance: The role of the cleavage form of gasdermin D.

    Rossi, Federico / Votto, Martina / Castagnoli, Riccardo

    Allergy

    2024  

    Language English
    Publishing date 2024-02-25
    Publishing country Denmark
    Document type News
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.16076
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  2. Article ; Online: Editorial comment on the special issue "Omics in food allergy".

    Castagnoli, Riccardo / Taietti, Ivan / Leung, Agnes Sze-Yin / Eigenmann, Philippe

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2024  Volume 35, Issue 3, Page(s) e14113

    MeSH term(s) Humans ; Food Hypersensitivity/diagnosis ; Multiomics
    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.14113
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  3. Article ; Online: Focus on biological therapies in pediatric allergy

    Francesca Cenzato / Riccardo Castagnoli / Gian Luigi Marseglia

    Global Pediatrics, Vol 7, Iss , Pp 100102- (2024)

    1481  

    Abstract: Biological therapies targeting specific cytokines and receptors provide successful treatment options for pediatric patients with allergic diseases. Defining their indications, dosing, and safety profiles is essential for optimizing outcomes and improving ...

    Abstract Biological therapies targeting specific cytokines and receptors provide successful treatment options for pediatric patients with allergic diseases. Defining their indications, dosing, and safety profiles is essential for optimizing outcomes and improving the quality of life for children with allergic chronic conditions.
    Keywords Pediatric allergy ; Asthma ; Atopic dermatitis ; Biological therapy ; Precision medicine ; Pediatrics ; RJ1-570
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Tracing and vaccinating: how to REACT to COVID-19 pandemic.

    Castagnoli, Riccardo / Marseglia, Gian Luigi

    The Lancet. Respiratory medicine

    2022  Volume 10, Issue 4, Page(s) 317–318

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Contact Tracing ; Humans ; Mobile Applications ; Pandemics/prevention & control
    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(22)00016-9
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  5. Article ; Online: Editorial comment on "Inborn errors of immunity associated with defects of thymic development".

    Beken, Burcin / Castagnoli, Riccardo / Candotti, Fabio

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2022  Volume 33, Issue 9, Page(s) e13847

    Language English
    Publishing date 2022-09-26
    Publishing country England
    Document type Editorial
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13847
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    Zs.A 3096: Show issues Location:
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  6. Article ; Online: Intra-patient and inter-observer image quality analysis in liver MRI study with gadoxetic acid using two different multi-arterial phase techniques.

    Castagnoli, Francesca / Faletti, Riccardo / Inchingolo, Riccardo / Villanacci, Alberta / Ruggeri, Valeria / Zacà, Domenico / Koh, Dow-Mu / Grazioli, Luigi

    The British journal of radiology

    2024  Volume 97, Issue 1156, Page(s) 868–873

    Abstract: Purpose: To evaluate intra-patient and interobserver agreement in patients who underwent liver MRI with gadoxetic acid using two different multi-arterial phase (AP) techniques.: Methods: A total of 154 prospectively enrolled patients underwent ... ...

    Abstract Purpose: To evaluate intra-patient and interobserver agreement in patients who underwent liver MRI with gadoxetic acid using two different multi-arterial phase (AP) techniques.
    Methods: A total of 154 prospectively enrolled patients underwent clinical gadoxetic acid-enhanced liver MRI twice within 12 months, using two different multi-arterial algorithms: CAIPIRINHA-VIBE and TWIST-VIBE. For every patient, breath-holding time, body mass index, sex, age were recorded. The phase without contrast media and the APs were independently evaluated by two radiologists who quantified Gibbs artefacts, noise, respiratory motion artefacts, and general image quality. Presence or absence of Gibbs artefacts and noise was compared by the McNemar's test. Respiratory motion artefacts and image quality scores were compared using Wilcoxon signed rank test. Interobserver agreement was assessed by Cohen kappa statistics.
    Results: Compared with TWIST-VIBE, CAIPIRINHA-VIBE images had better scores for every parameter except higher noise score. Triple APs were always acquired with TWIST-VIBE but failed in 37% using CAIPIRINHA-VIBE: 11% have only one AP, 26% have two. Breath-holding time was the only parameter that influenced the success of multi-arterial techniques. TWIST-VIBE images had worst score for Gibbs and respiratory motion artefacts but lower noise score.
    Conclusion: CAIPIRINHA-VIBE images were always diagnostic, but with a failure of triple-AP in 37%. TWIST-VIBE was successful in obtaining three APs in all patients. Breath-holding time is the only parameter which can influence the preliminary choice between CAIPIRINHA-VIBE and TWIST-VIBE algorithm.
    Advances in knowledge: If the patient is expected to perform good breath-holds, TWIST-VIBE is preferable; otherwise, CAIPIRINHA-VIBE is more appropriate.
    MeSH term(s) Humans ; Image Interpretation, Computer-Assisted/methods ; Image Enhancement/methods ; Reproducibility of Results ; Magnetic Resonance Imaging/methods ; Contrast Media ; Breath Holding ; Artifacts ; Liver/diagnostic imaging ; Gadolinium DTPA
    Chemical Substances gadolinium ethoxybenzyl DTPA ; Contrast Media ; Gadolinium DTPA (K2I13DR72L)
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1093/bjr/tqae045
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  7. Article ; Online: COVID-19 and Inborn Errors of Immunity.

    Delmonte, Ottavia M / Castagnoli, Riccardo / Notarangelo, Luigi D

    Physiology (Bethesda, Md.)

    2022  Volume 37, Issue 6

    Abstract: Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune host defense and immunoregulation. Considering the predisposition to develop severe and chronic infections, it is crucial to understand the clinical evolution of ... ...

    Abstract Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune host defense and immunoregulation. Considering the predisposition to develop severe and chronic infections, it is crucial to understand the clinical evolution of COVID-19 in IEI patients. This review analyzes clinical outcomes following SARS-CoV-2 infection, as well as response to COVID-19 vaccines in patients with IEI.
    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; Immunity ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-08-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2158667-6
    ISSN 1548-9221 ; 1548-9213
    ISSN (online) 1548-9221
    ISSN 1548-9213
    DOI 10.1152/physiol.00016.2022
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  8. Article ; Online: Resilience is low in adolescents with asthma and independent of asthma control.

    Ciprandi, Giorgio / Marseglia, Gian Luigi / Licari, Amelia / Castagnoli, Riccardo / Ciprandi, Riccardo

    Acta bio-medica : Atenei Parmensis

    2022  Volume 93, Issue 2, Page(s) e2022054

    Abstract: N/A. ...

    Abstract N/A.
    MeSH term(s) Adolescent ; Asthma ; Humans
    Language English
    Publishing date 2022-05-11
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v93i2.11751
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    Zs.B 925: Show issues Location:
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  9. Article ; Online: Congenital and acquired defects of immunity: An ever-evolving story.

    Castagnoli, Riccardo / Delmonte, Ottavia M / Notarangelo, Luigi D

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2022  Volume 33 Suppl 27, Page(s) 61–64

    Abstract: Inborn errors of immunity (IEI), also referred to as primary immunodeficiencies (PID), are disorders that, for the most part, result from mutations in genes involved in immune host defense and immune regulation. With the increased availability of high- ... ...

    Abstract Inborn errors of immunity (IEI), also referred to as primary immunodeficiencies (PID), are disorders that, for the most part, result from mutations in genes involved in immune host defense and immune regulation. With the increased availability of high-throughput DNA sequencing and improved genomic data interpretation, the number of newly identified genes associated with IEI has exponentially increased over the last decade. Here, we focus on the newly described IEI associated with severe COVID-19 and SASH3 deficiency, the most recently reported IEI with impaired T-cell receptor (TCR) signaling.
    MeSH term(s) COVID-19 ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation ; Primary Immunodeficiency Diseases ; SARS-CoV-2
    Language English
    Publishing date 2022-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13632
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  10. Article ; Online: Updates on new monogenic inborn errors of immunity.

    Castagnoli, Riccardo / Notarangelo, Luigi Daniele

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2020  Volume 31 Suppl 26, Page(s) 57–59

    Abstract: Inborn errors of immunity (IEI), also referred to as primary immunodeficiencies (PID), are disorders that, for the most part, result from mutations in genes involved in immune host defense and immune regulation. Thanks to the increased availability of ... ...

    Abstract Inborn errors of immunity (IEI), also referred to as primary immunodeficiencies (PID), are disorders that, for the most part, result from mutations in genes involved in immune host defense and immune regulation. Thanks to the increased availability of high-throughput DNA sequencing and the improvement in genomic data interpretation, the number of newly identified genes associated with IEI has exponentially increased over the last decade. We reviewed four recently described monogenic IEI and discussed the clinical and immunologic features of these new conditions.
    MeSH term(s) High-Throughput Nucleotide Sequencing ; Humans ; Immunologic Deficiency Syndromes/genetics ; Mutation ; Primary Immunodeficiency Diseases
    Language English
    Publishing date 2020-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13365
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