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  1. Article ; Online: Severe Acute Respiratory Syndrome-Coronavirus-2 Infection and Patients With Lung Cancer: The Potential Role of Interleukin-17 Target Therapy.

    Cafarotti, Stefano

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2020  Volume 15, Issue 7, Page(s) e101–e103

    Abstract: The coronavirus disease 2019 outbreak is evolving rapidly worldwide. The lungs are the target of the primary infection and patients with lung cancer seem to have a poor prognosis. To our knowledge, this is the first reported investigation of a possible ... ...

    Abstract The coronavirus disease 2019 outbreak is evolving rapidly worldwide. The lungs are the target of the primary infection and patients with lung cancer seem to have a poor prognosis. To our knowledge, this is the first reported investigation of a possible role of interleukin-17 target therapy in patients with lung cancer and concomitant severe acute respiratory syndrome-coronavirus-2 infection.
    MeSH term(s) Betacoronavirus/drug effects ; Betacoronavirus/physiology ; COVID-19 ; Chemokines, CXC/metabolism ; Coronavirus Infections/drug therapy ; Coronavirus Infections/immunology ; Drug Discovery ; Humans ; Inflammation/immunology ; Interleukin-17/antagonists & inhibitors ; Interleukin-17/immunology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/immunology ; Molecular Targeted Therapy/methods ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/immunology ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/immunology ; SARS-CoV-2 ; Th17 Cells/immunology ; Up-Regulation/drug effects
    Chemical Substances Chemokines, CXC ; Interleukin-17
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2020.04.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: SARS-COV2 INFECTION AND LUNG CANCER PATIENTS: the potential role of IL17 target therapy

    Cafarotti, Stefano

    Journal of Thoracic Oncology

    Abstract: Abstract The coronavirus disease 2019 (Covid-19) outbreak is evolving rapidly worldwide. The Lung is the target organ of the primary infection and patient whit lung cancer seems to have a poor prognosis. This is the first reported investigation on a ... ...

    Abstract Abstract The coronavirus disease 2019 (Covid-19) outbreak is evolving rapidly worldwide. The Lung is the target organ of the primary infection and patient whit lung cancer seems to have a poor prognosis. This is the first reported investigation on a possible role of IL 17 target therapy in Lung Cancer patients with concomitant Sars-CoV2 infection.
    Keywords covid19
    Publisher Elsevier
    Document type Article ; Online
    DOI 10.1016/j.jtho.2020.04.015
    Database COVID19

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  3. Article: Severe Acute Respiratory Syndrome-Coronavirus-2 Infection and Patients With Lung Cancer: The Potential Role of Interleukin-17 Target Therapy

    Cafarotti, Stefano

    J Thorac Oncol

    Abstract: The coronavirus disease 2019 outbreak is evolving rapidly worldwide. The lungs are the target of the primary infection and patients with lung cancer seem to have a poor prognosis. To our knowledge, this is the first reported investigation of a possible ... ...

    Abstract The coronavirus disease 2019 outbreak is evolving rapidly worldwide. The lungs are the target of the primary infection and patients with lung cancer seem to have a poor prognosis. To our knowledge, this is the first reported investigation of a possible role of interleukin-17 target therapy in patients with lung cancer and concomitant severe acute respiratory syndrome-coronavirus-2 infection.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #291629
    Database COVID19

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  4. Article ; Online: Resection of thymic carcinoma after induction therapy and reconstruction of right ventricular outflow tract with pulmonary homograft.

    Cafarotti, Stefano / Torre, Tiziano M / Patella, Miriam / Demertzis, Stefanos

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2023  Volume 63, Issue 4

    Abstract: Treatment of malignant epithelial thymic tumours, including thymoma and thymic carcinoma, is based on surgical resection, whenever possible. Mainstay of surgical treatment is complete resection with clear margins. This may require resection of adjacent ... ...

    Abstract Treatment of malignant epithelial thymic tumours, including thymoma and thymic carcinoma, is based on surgical resection, whenever possible. Mainstay of surgical treatment is complete resection with clear margins. This may require resection of adjacent structures, even major vessels. We describe a case of resection of the main pulmonary artery trunk and reconstruction with cadaveric homograft after induction chemo-radiotherapy for a locally advanced thymic carcinoma. Written informed consent was obtained from the patient.
    MeSH term(s) Humans ; Thymoma/surgery ; Thymoma/pathology ; Induction Chemotherapy ; Treatment Outcome ; Thymus Neoplasms/surgery ; Thymus Neoplasms/pathology ; Carcinoma/therapy ; Allografts
    Language English
    Publishing date 2023-02-24
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezad069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2303: Show issues Location:
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  5. Article ; Online: Lung Cancer Surgical Management During the Outbreak of Coronavirus Disease 2019.

    Cafarotti, Stefano / Patella, Miriam

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2020  Volume 15, Issue 6, Page(s) e81

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Lung Neoplasms ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2020.03.027
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  6. Article ; Online: Reply.

    Patella, Miriam / Cafarotti, Stefano

    The Annals of thoracic surgery

    2019  Volume 109, Issue 1, Page(s) 310–311

    MeSH term(s) Humans ; Pneumothorax ; Pulmonary Surgical Procedures ; Ultrasonography
    Language English
    Publishing date 2019-06-15
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2019.05.007
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    Zs.A 252: Show issues Location:
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  7. Article: Urban-Rural Disparities in the Lung Cancer Surgical Treatment Pathway: The Paradox of a Rich, Small Region.

    Minerva, Eleonora Maddalena / Tessitore, Adele / Cafarotti, Stefano / Patella, Miriam

    Frontiers in surgery

    2022  Volume 9, Page(s) 884048

    Abstract: Introduction: Rural populations in large countries often receive delayed or less effective diagnosis and treatment for lung cancer. Differences are related to population-based factors such as lower pro capita income or increased risk factors or to ... ...

    Abstract Introduction: Rural populations in large countries often receive delayed or less effective diagnosis and treatment for lung cancer. Differences are related to population-based factors such as lower pro capita income or increased risk factors or to differences in access to facilities. Switzerland is a small, rich country with peculiar geographic and urban characteristics.We explored the relationship between lung cancer diagnostic-surgical pathway and urban-rural residency in our region.
    Methods: We retrospectively analyzed the medical records of 280 consecutive patients treated for primary non-small cell lung cancer at our institution (2017-2021). This is a regional tertiary center for diagnosis and treatment, and data were extracted from a prospectively collected clinical database. We included anatomical lung resection. Collected variables included patients and surgical characteristics, risk factors, comorbidities, histology and staging, symptoms (vs. incidental diagnosis), general practitioner (GP) involvement, health insurance, and suspected test-treatment interval. The exposure was rurality, defined by the 2009 rural-urban residency classification from the Department of Land.
    Results: A total of 150 patients (54%) lived in rural areas. Rural patients had a higher rate of smoking history (93% vs. 82%;
    Conclusions: In our territory with inhomogeneous population distribution and geographic barriers, residency has an impact on the lung cancer pathway. It seems paradoxical that rural patients had a shorter route. The more constant involvement of GP might explain this finding, having suggested more tests for high-risk patients in the absence of symptoms or follow-ups. This did not change the staging of surgical patients, but it might be essential for the organization of an effective lung cancer screening program.
    Language English
    Publishing date 2022-04-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.884048
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  9. Article: The importance of asking the right questions: the role of chest ultrasound in thoracic surgery.

    Patella, Miriam / Mongelli, Francesco / Cafarotti, Stefano

    Journal of thoracic disease

    2019  Volume 11, Issue Suppl 3, Page(s) S359–S362

    Language English
    Publishing date 2019-04-09
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.12.81
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  10. Article ; Online: Reply.

    Patella, Miriam / FitzGerald, Maurice / Cafarotti, Stefano

    The Annals of thoracic surgery

    2019  Volume 108, Issue 3, Page(s) 961

    MeSH term(s) Humans ; Pneumothorax ; Pulmonary Surgical Procedures ; Ultrasonography
    Language English
    Publishing date 2019-04-11
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2019.03.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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