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  1. Article ; Online: Comparison of the rate of change (slopes) in impact factor of medical imaging journals unveils journals with organic growth: An observational study (2016-2022).

    Martínez-Greiser, Paola / Garcia-Lezama, Melissa / Rivera-Ibarguen, Santiago / Roldan-Valadez, Ernesto

    Journal of cardiovascular computed tomography

    2023  Volume 17, Issue 5, Page(s) 365–366

    MeSH term(s) Humans ; Journal Impact Factor ; Predictive Value of Tests ; Periodicals as Topic ; Diagnostic Imaging
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Observational Study ; Letter
    ZDB-ID 2394360-9
    ISSN 1876-861X ; 1934-5925
    ISSN (online) 1876-861X
    ISSN 1934-5925
    DOI 10.1016/j.jcct.2023.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Top 100 Most Cited Papers on Multimodality Imaging for Complex Congenital Heart Disease. A Bibliometric Analysis.

    Rivera-Ibarguen, Santiago / Jiménez-Carbajal, María-Guadalupe / Gamboa-Lopez, Christian-Alessandro / Garcia-Lezama, Melissa / Roldan-Valadez, Ernesto

    Current problems in cardiology

    2023  Volume 49, Issue 1 Pt A, Page(s) 102028

    Abstract: Complex congenital heart disease (CCHD) is a group of heart defects present at birth. Some imaging methods can support the diagnosis of these pathologies, such as echocardiography, computed tomography, and magnetic resonance imaging. This study aimed to ... ...

    Abstract Complex congenital heart disease (CCHD) is a group of heart defects present at birth. Some imaging methods can support the diagnosis of these pathologies, such as echocardiography, computed tomography, and magnetic resonance imaging. This study aimed to perform a bibliometric analysis of the top 100 articles cited on CCHD. Articles from 2013 to 2023 found in Scopus were scanned using 15 CCHD topics titles crossed with echocardiography, computed tomography, and magnetic resonance imaging. Duplicated manuscripts were eliminated using Microsoft Excel software, and the publications were ranked according to their citation count. This study selected and analyzed the top 100 most cited English-language papers. The top 100 most cited publications accumulated 16,563 citations. The manuscript with the most citations obtained 1086, representing 6.55% of the total citations. The year 2014 had the highest number of publications, with 27 papers. The first authors had affiliations from 44 countries; the United States was the country that contributed the most, with 54 manuscripts. Boston Children's Hospital was the institution that provided more articles to the top 100. Finally, the Ebstein anomaly was the topic with the highest number of citations. This study identified the 100 most cited on CCHD, and the results obtained can provide practical guidance to clinicians and researchers to familiarize themselves with the most influential publications in this field.
    MeSH term(s) Infant, Newborn ; Child ; Humans ; United States ; Bibliometrics ; Tomography, X-Ray Computed ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2023.102028
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  3. Article ; Online: Severe Acute Respiratory Syndrome Coronavirus 2 Spreads to Lymph Nodes and Strongly Expands CD4+ Effector Memory RA Cells in a Patient With Mild Coronavirus Disease 2019.

    Roldán-Santiago, Ernesto / Benito-Berlinches, Amparo / Martínez-García, Laura / Quereda, Carmen / Rodríguez-Martín, Eulalia / Pérez-Elías, Pilar / López-Pintor, Jose María / Walo-Delgado, Paulette Esperanza / Moreno-Zamora, Ana / Fernández-Velasco, Jose Ignacio / García-Abellás, Patricia / Ballester-González, Rubén / Villar, Luisa M / Pérez-Elías, María Jesús

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 73, Issue 11, Page(s) e3970–e3973

    Abstract: A woman with mild coronavirus disease 2019 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. We performed fine needle aspiration, and demonstrate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV- ... ...

    Abstract A woman with mild coronavirus disease 2019 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. We performed fine needle aspiration, and demonstrate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found in lymph nodes even in mild disease along with a strong expansion of terminally differentiated effector memory CD4+ T cells, a cell population that is practically absent in lymph nodes.
    MeSH term(s) CD4-Positive T-Lymphocytes ; COVID-19 ; Epstein-Barr Virus Infections ; Female ; Herpesvirus 4, Human ; Humans ; Lymph Nodes ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa1422
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  4. Article ; Online: Patients with secondary acute myeloid leukemia undergoing allogeneic stem-cell transplant have inferior outcomes than de novo acute myeloid leukemia regardless minimal residual disease level by flow cytometry.

    Núñez-Torrón Stock, Claudia / Jiménez Chillón, Carlos / Martín Moro, Fernando / Marquet Palomanes, Juan / Velázquez Kennedy, Kyra / Piris Villaespesa, Miguel / Roldán Santiago, Ernesto / Rodríguez Martín, Eulalia / Chinea Rodríguez, Anabelle / García Gutiérrez, Valentín / Moreno Jiménez, Gemma / López Jiménez, Javier / Herrera Puente, Pilar

    Hematological oncology

    2023  Volume 41, Issue 4, Page(s) 753–761

    Abstract: Secondary acute myeloid leukemia (s-AML) patients have a poor prognosis and currently the only curative therapy is allogeneic stem-cell transplant (HSCT). However, we do not yet know whether transplantation is sufficient to reverse the poor prognosis ... ...

    Abstract Secondary acute myeloid leukemia (s-AML) patients have a poor prognosis and currently the only curative therapy is allogeneic stem-cell transplant (HSCT). However, we do not yet know whether transplantation is sufficient to reverse the poor prognosis compared to de novo AML patients. We analyzed survival after HSCT comparing a cohort of 58 patients with s-AML versus 52 de novo patients who were transplanted between 2012 and 2020. Patients with s-AML had worse event-free survival (EFS) (p = 0.001) and overall survival (OS) (p < 0.001) compared to de novo AML due to an increased risk of relapse (p = 0.06) and non-relapse mortality (p = 0.03). The main difference in survival was observed in patients who achieved complete remission (CR) before HSCT (EFS p = 0.002 OS and <0.001), regardless minimal residual disease (MRD) by |multiparametric flow cytometry cohorts. In patients transplanted with active disease (AD), the prognosis was adverse in both s-AML and de novo AML groups (EFS p = 0.869 and OS p = 0.930). After excluding patients with AD, we stratified the cohort according to conditioning intensity, noticing that s-AML who received MAC had comparable outcomes to de novo AML, but the survival differences remained among reduce intensity conditioning group. In conclusion, transplanted s-AML patients have worse survival among patients in CR before HSCT, regardless of MRD level by flow cytometry compared to de novo AML. MAC patients had similar outcomes irrespective of leukemia ontogeny.
    MeSH term(s) Humans ; Hematopoietic Stem Cell Transplantation ; Neoplasm, Residual ; Flow Cytometry ; Transplantation, Homologous ; Leukemia, Myeloid, Acute/therapy ; Prognosis ; Neoplasms, Second Primary ; Retrospective Studies
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.3160
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  5. Article: SARS-CoV-2 spreads to lymph nodes and strongly expands CD4+ TEMRA cells in a patient with mild COVID-19

    Roldán-Santiago, Ernesto / Benito-Berlinches, Amparo / Martínez-García, Laura / Quereda, Carmen / Rodríguez-Martín, Eulalia / Pérez-Elías, Pilar / López-Pintor, Jose María / Walo-Delgado, P E / Moreno-Zamora, Ana / Fernández-Velasco, Jose Ignacio / García-Abellás, Patricia / Ballester-González, Rubén / Villar, Luisa M / Pérez-Elías, María Jesús

    Clin. infect. dis

    Abstract: A woman with mild Covid-19 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. After a FNAP we demonstrate that SARS-CoV-2 is found in lymph nodes (LNs) even in mild disease along with a strong expansion of ... ...

    Abstract A woman with mild Covid-19 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. After a FNAP we demonstrate that SARS-CoV-2 is found in lymph nodes (LNs) even in mild disease along with a strong expansion of terminally differentiated effector memory CD4+T-cells , a cell population that is practically absent in LN.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #780350
    Database COVID19

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  6. Article ; Online: Severe Acute Respiratory Syndrome Coronavirus 2 Spreads to Lymph Nodes and Strongly Expands CD4+ Effector Memory RA Cells in a Patient With Mild Coronavirus Disease 2019

    Roldán-Santiago, Ernesto / Benito-Berlinches, Amparo / Martínez-García, Laura / Quereda, Carmen / Rodríguez-Martín, Eulalia / Pérez-Elías, Pilar / López-Pintor, Jose María / Walo-Delgado, Paulette Esperanza / Moreno-Zamora, Ana / Fernández-Velasco, Jose Ignacio / García-Abellás, Patricia / Ballester-González, Rubén / Villar, Luisa M / Pérez-Elías, María Jesús

    Clinical Infectious Diseases ; ISSN 1058-4838 1537-6591

    2020  

    Abstract: Abstract A woman with mild coronavirus disease 2019 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. We performed fine needle aspiration, and demonstrate that severe acute respiratory syndrome coronavirus 2 ( ... ...

    Abstract Abstract A woman with mild coronavirus disease 2019 developed cervical adenopathy, being diagnosed of Epstein-Barr virus infectious mononucleosis. We performed fine needle aspiration, and demonstrate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found in lymph nodes even in mild disease along with a strong expansion of terminally differentiated effector memory CD4+ T cells, a cell population that is practically absent in lymph nodes.
    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/cid/ciaa1422
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis.

    Madera, Santiago / Chervo, María F / Chiauzzi, Violeta A / Pereyra, Matías G / Venturutti, Leandro / Izzo, Franco / Roldán Deamicis, Agustina / Guzman, Pablo / Dupont, Agustina / Roa, Juan Carlos / Cenciarini, Mauro E / Barchuk, Sabrina / Figurelli, Silvina / Lopez Della Vecchia, Daniel / Levit, Claudio / Lebersztein, Gabriel / Anfuso, Fabiana / Castiglioni, Teresa / Cortese, Eduardo /
    Ares, Sandra / Deza, Ernesto Gil / Gercovich, Felipe G / Proietti, Cecilia J / Schillaci, Roxana / Cordo Russo, Rosalía I / Elizalde, Patricia V

    Hormones & cancer

    2020  Volume 11, Issue 5-6, Page(s) 218–239

    Abstract: The hormone receptor-positive (estrogen and/or progesterone receptor (PR)-positive) and HER2-negative breast cancer (BC) subtype is a biologically heterogeneous entity that includes luminal A-like (LumA-like) and luminal B-like (LumB-like) subtypes. ... ...

    Abstract The hormone receptor-positive (estrogen and/or progesterone receptor (PR)-positive) and HER2-negative breast cancer (BC) subtype is a biologically heterogeneous entity that includes luminal A-like (LumA-like) and luminal B-like (LumB-like) subtypes. Decreased PR levels is a distinctive biological feature of LumB-like tumors. These tumors also show reduced sensitivity to endocrine therapies and poorer prognosis than LumA-like tumors. Identification of biomarkers to accurately predict disease relapse in these subtypes is crucial in order to select effective therapies. We identified the tumor suppressor PDCD4 (programmed cell death 4), located in the nucleus (NPDCD4), as an independent prognostic factor of good clinical outcome in LumA-like and LumB-like subtypes. NPDCD4-positive LumB-like tumors presented overall and disease-free survival rates comparable to those of NPDCD4-positive LumA-like tumors, indicating that NPDCD4 improves the outcome of LumB-like patients. In contrast, NPDCD4 loss increased the risk of disease recurrence and death in LumB-like compared with LumA-like tumors. This, along with our results showing that LumB-like tumors present lower NPDCD4 positivity than LumA-like tumors, suggests that NPDCD4 loss contributes to endocrine therapy resistance in LumB-like BCs. We also revealed that PR induces PDCD4 transcription in LumB-like BC, providing a mechanistic explanation to the low PDCD4 levels in LumB-like BCs lacking PR. Finally, PDCD4 silencing enhanced BC cell survival in a patient-derived explant model of LumB-like disease. Our discoveries highlight NPDCD4 as a novel biomarker in LumA- and LumB-like subtypes, which could be included in the panel of immunohistochemical markers used in the clinic to accurately predict the prognosis of LumB-like tumors.
    MeSH term(s) Apoptosis Regulatory Proteins/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Humans ; Prognosis ; RNA-Binding Proteins/metabolism
    Chemical Substances Apoptosis Regulatory Proteins ; PDCD4 protein, human ; RNA-Binding Proteins
    Language English
    Publishing date 2020-07-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2543318-0
    ISSN 1868-8500 ; 1868-8500
    ISSN (online) 1868-8500
    ISSN 1868-8500
    DOI 10.1007/s12672-020-00392-4
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  8. Article ; Online: New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy.

    Bravo García-Morato, María / Aracil Santos, Francisco Javier / Briones, Alejandro Contreras / Blázquez Moreno, Alfonso / Del Pozo Maté, Ángela / Domínguez-Soto, Ángeles / Beato Merino, María José / Del Pino Molina, Lucía / Torres Canizales, Juan / Marin, Ana Victoria / Vallespín García, Elena / Feito Rodríguez, Marta / Plaza López Sabando, Diego / Jiménez-Reinoso, Anaïs / Mozo Del Castillo, Yasmina / Sanz Santaeufemia, Francisco José / de Lucas-Laguna, Raúl / Cárdenas, Paula P / Casamayor Polo, Laura /
    Coronel Díaz, María / Valés-Gómez, Mar / Roldán Santiago, Ernesto / Ferreira Cerdán, Antonio / Nevado Blanco, Julián / Corbí, Ángel L / Reyburn, Hugh T / Regueiro, José Ramón / López-Granados, Eduardo / Rodríguez Pena, Rebeca

    The Journal of allergy and clinical immunology

    2018  Volume 141, Issue 5, Page(s) 1924–1927.e18

    MeSH term(s) Animals ; Cells, Cultured ; Female ; Humans ; Immunologic Deficiency Syndromes/immunology ; Infant ; Interferon Regulatory Factors/immunology ; Mice ; Uniparental Disomy/immunology
    Chemical Substances Interferon Regulatory Factors ; interferon regulatory factor-4
    Language English
    Publishing date 2018-03-02
    Publishing country United States
    Document type Case Reports ; Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2017.12.995
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  9. Article ; Online: Global attitudes in the management of acute appendicitis during COVID-19 pandemic

    B, Ielpo / M, Podda / G, Pellino / F, Pata / R, Caruso / G, Gravante / Saverio, Di / Orengia, Adam / Chowdary, Aditya / Kulkarni, Aditya / Kuvvetli, Adnan / Navarro, Adolfo / Pisanu, Adolfo / Smith, Adrian / Cavero Ibiricu, Adriana / Nacion, Aeris Jane D. / Alsaleh, Ahmad / Alhazmi, Ahmad / Elmabri, Ahmad /
    Wani, Ajaz / Rencuzogullari, Ahmet / Sarriugarte Lasarte, Aingeru / Valle Rubio, Ainhoa / Bavikatte, Akshay / Kumar, Akshay / Jamiri, Al-radjid / Michel Alvarado Padilla, Alain / Cacurri, Alban / de San Ildefonso, Alberto / Porcu, Alberto / Sartori, Alberto / Rocca, Aldo / Paz Yáñez, Alejandro / Becaria, Alejandro / Solís-Peña, Alejandro / Sretenović, Aleksandar / Urbistondo, Alex / Bandin, Alfonso / Najar, Alfonso / De Luca, Alessandro / Boddy, Alex / Charalabopoulos, Alexandros / Tzivanakis, Alexios / Amendola, Alfonso / Ramirez-Gutierrez de Velasco, Alfredo / Cihat Yildirim, Ali / Frontali, Alice / Oumar Toure, Alpha / García-Granero, Alvaro / Martínez Roldan, Amaia / Sanz Larrainzar, Amaia / Sanjiva Ratnayake, Amila / María Gonzalez-Ganso, Ana / Minaya-Bravo, Ana M. / Das, Andre / Bondurri, Andrea / Costanzi, Andrea / Lucchi, Andrea / Mazzari, Andrea / Musig, Andrea / Peloso, Andrea / Piano, Andrea / Police, Andrea / Mihailescu, Andrei / Pouy, Andrés / Romano, Angela / Iossa, Angelo / Carmen Leonetti, Anna / Guariniello, Anna / Isaac, Anna / Pia Delli Bovi, Anna / Chessa, Antonella / Tromba, Antonella / Álvarez Martínez, Antonio / Brillantino, Antonio / Caira, Antonio / Castaldi, Antonio / Ferronetti, Antonio / Giuliani, Antonio / Prestera, Antonio / Ramos-De la Medina, Antonio / Tarasconi, Antonio / Tornambè, Antonino / Picciariello, Arcangelo / Ioannidis, Argyrios / Leppäniemi, Ari / Khan, Arshad / Rashid, Arshad / Luis Eduardo Pérez-Sánchez, Arteaga / Mittal, Ashok / Rahman Mitul, Ashrarur / Mehraj, Asif / Laharwal, Asim / Dorismé, Asnel / Marinis, Athanasios / Iqbal, Atif / Moncada, Augusto / Braccio, Bartolomeo / Alkhafaji, Basim / de Andrés Asenjo, Beatriz / Martin-Perez, Beatriz / De Simone, Belinda / Sánchez Pérez, Belinda / Creavin, Ben / Calì, Benedetto / Cali, Benedetto / Pascotto, Beniamino / Stubbs, Benjamin / Zavala Retes, Benjamin / Jovanovic, Branislav / KP Goh, Brian / Sensi, Bruno / Biddau, Carlo / Gazia, Carlo / Vallicelli, Carlo / Alberto Fagundes, Carlos / Cerdán Santacruz, Carlos / Chirico, Carlos / Javier Gómez Díaz, Carlos / Petrola, Carlos / Sánchez Rodriguez, Carlos / Yánez Benítez, Carlos / Dammaro, Carmelisa / Lo Faro, Carmelo / Reinke, Caroline / Dominguez Paez, Casandra / Oliva, Catalina / Paranjape, Charudutt / Thomas, Charlotte / Fung Chia, Chi / Kwan Kong, Chi / De Lucia, Chiara / Ovalle Chao, Christian / Arcudi, Claudio / Guerci, Claudio / Chia, Clement / Parise, Cristiano / Folliero, Cristina / Varela, Cristopher / Ferguson, Dalya M. / Camacho, Daniel / Popowich, Daniel / Souza Lima, Daniel / Rega, Daniela / Delogu, Daniele / Zigiotto, Daniele / Vinci, Danilo / D’Antonio, Dario / Parini, Dario / Alessio Merlini, David / DE Zimmerman, David / Moro-Valdezate, David / Pertile, Davide / Maria Giusti, Deborah / Keller, Deborah S. / Tarik, Delko / Kalivaçi, Denis / Mazingi, Dennis / Gabriela Maldonado-Pintado, Diana / Sasia, Diego / Linardoutsos, Dimitrios / Osilli, Dixon / Murrone, Domenico / Russello, Domenico / Rodas, Edgar / Alberto Acuña Roa, Edisson / Ricciardi, Edoardo / Rosso, Edoardo / Saladino, Edoardo / Flores-Villalba, Eduardo / Ruiz Ajs, Eduardo / Smith-Singares, Eduardo / Baili, Efstratia / Kouroumpas, Efstratios / Bourmpouteli, Eirini / Douka, Eleftheria / Martin-Perez, Elena / Guaitoli, Eleonora / Samadov, Elgun / Francone, Elisa / Vaterlini, Elisa / Morales, Emilio / Peña, Emilio / Zhao, Enhao / Del Pozo Andres, Eneko / Benzoni, Enrico / Erdas, Enrico / Pinotti, Enrico / Colás-Ruiz, Enrique / Aytac, Erman / Laterza, Ernesto / Agastra, Ervis / Foianini, Esteban / Moscoso, Esteban / Laviano, Estefania / Marra, Ester / Cardamone, Eugenia / Licardie, Eugenio / Mpaili, Eustratia / Pinna, Eva / Varo, Evaristo / Martín Navarro, Fabian / Marino, Fabio / Medas, Fabio / Romano, Fabio / Maraska, Fatlum / Saliu, Fatmir / Madrid, Fausto / Rosa, Fausto / Mastella, Federica / Gheza, Federico / Luvisetto, Federico / Alconchel, Felipe / Monge Vieira, Felipe / Pareja, Felipe / Agresta, Ferdinando / Luna, Fernanda / Bonilla, Fernando / Cordera, Fernando / Burdió, Fernando / Mendoza-Moreno, Fernando / Muñoz Flores, Fernando / Pardo Aranda, Fernando / Taylor, Fiona / Ramos, Flavia L. / Fernandes, Flavio / Paola Tropeano, Francesca / Balestra, Francesco / Bianco, Francesco / Ceci, Francesco / Colombo, Francesco / Di Marzo, Francesco / Ferrara, Francesco / Lancellotti, Francesco / Lazzarin, Francesco / Litta, Francesco / Martini, Francesco / Pizza, Francesco / Roscio, Francesco / Virdis, Francesco / Blanco Antona, Francisco / Cervantes Ramírez, Francisco / Miguel Fernandez, Francisco / Oliver Llinares, Francisco / Quezada, Francisco / Schlottmann, Francisco / Quezada, Fransisco / Herrera-Almario, Gabriel / Massaferro, Gabriel / Bislenghi, Gabriele / van Ramshorst, Gabrielle / Gallo, Gaetano / Luglio, Gaetano / Bointas, Georgios / Kampouroglou, Georgios / Papadopoulos, Georgios / Arredondo Manrique, Gerardo / Calini, Giacomo / Nastri, Giacomo / Formisano, Giampaolo / Galiffa, Giampaolo / Marco Palini, Gian / Colucci, Gianluca / Pagano, Gianluca / Pellino, Gianluca / Vanni, Gianluca / Casoni Pattacini, Gianmaria / Gravante, Gianpiero / De Paola, Gilda / Lisi, Giorgio / Partida, Giovanna / Bellanova, Giovanni / De Nobili, Giovanni / Sammy Necchi, Giovanni / Sinibaldi, Giovanni / Tebala, Giovanni / Bagaglini, Giulia / Izzo, Giuliano / Argenio, Giulio / Brisinda, Giuseppe / Candilio, Giuseppe / Di Grezia, Giuseppe / Esposito, Giuseppe / Faillace, Giuseppe / Frazzetta, Giuseppe / La Gumina, Giuseppe / Nigri, Giuseppe / Romeo, Giuseppe / Chocarro Amatriaín, Gloria / Ortega, Gloria / Martin-Martin, Gonzalo / Stavrou, Gregor A. / Gunadi, / Armand Ugon, Gustavo / Machain, Gustavo / Marcucci, Gustavo / Martínez-Mier, Gustavo / Miguel Machain, Gustavo / Nari, Gustavo / Calvo, Haydée / Fathy, Hamada / Hamilto, / Ahmed, Hazem / Faraj, Hazem / Nava, Hector / Ordas Macias, Hector / Nikaj, Herald / Solano, Heriberto / Ahmed Khan, Huma / Sánchez Alarcón, Humberto / 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Richard / Justin Davies, Richard / Dholakia, Rishi / Rattan, Rishi / Singhal, Rishi / Lim, Robert / Angelico, Roberta / Maria Isernia, Roberta / Tutino, Roberta / Faccincani, Roberto / Peltrini, Roberto / Carrera-Ceron, Rocio / Tejos, Rodrigo / Kashyap, Rohit / Fajardo, Roosevelt / Lozito, Rosa / Madariaga Pareja, Royer / Garbarino, Sabrina / Di Saverio, Salomone / Morales-Conde, Salvador / Benli, Sami / Mansour, Sami / Flores, Samir / Limon Suarez, Samuel / Lopez Ben, Santiago / Fuentes, Sara / Gortazar de las Casas, Sara / Napetti, Sara / Ortiz de Guzmán, Sara / Awad, Selmy / Weckmann Luján, Sergio A. / Gentilli, Sergio / Grimaldi, Sergio / Olivares Pizarro, Sergio / Tayar, Serkan / Nabi, Shakeeb / M Chan, Shannon / Junaid, Sheikh / Rojas, Sidney / Monetti, Silvana / García, Silvia / Salvans, Silvia / Tenconi, Silvia / Shaw, Simon / Santoni, Simone / Andrea Parra, Sofia / Cárdenas, Sofía / Pérez-Bertólez, Sonia / Chiappetta, Sonja / Dessureault, Sophie / Delis, Spiros / Amore Bonapasta, Stefano / Rausei, Stefano / Scaringi, Stefano / Keswani, Sundeep / Muhammad Ali, Syed / Cetinkunar, Süleyman / Lit Derek Fung, Tak / Rawashdeh, Tariq / Nicolás López, Tatiana / De Campos, Tercio / Calderon Duque, Teresa / Perra, Teresa / Liakakos, Theodore / Daskalakis, Theodoros / Liakakos, Theodoros / Barnes, Thomas / Koëter, Tijmen / Zalla, Tiku / González, Tomás E. / Elosua, Tomás / Campagnaro, Tommaso / Brown, Tommy / Luoto, Topi / Alpha Oumar, Touré / Giustizieri, Ugo / Grossi, Ugo / Bracale, Umberto / Rivas, Uriel / Sosa, Valentina / Testa, Valentina / Andriola, Valeria / Tonini, Valeria / Balassone, Valerio / Celentano, Valerio / Progno, Valerio / Raju, Varun / Carroni, Vanessa / Cavallaro, Venera / Rao Katta, Venkateswara / De Simone, Veronica / Primo Romaguera, Vicent / Hugo García Orozco, Victor / Luraschi, Victor / Rachkov, Victor / Turrado-L, Victor / Visag-Castillo, Victor / Dowling, Victoria / Graham, Victoria / Papagni, Vincenzo / Vigorita, Vincenzo / Cordeiro Fonseca, Vinicius / Jimenez Carneros, Virginia / Bellato, Vittoria / Gonçalves, Walyson / Powers, William F. / Grigg, William / Bechstein, Wolf O. / Bing Lim, Yu / Altinel, Yuksel / Golubović, Zoran / Balciscueta, Zutoia

    ACIE Appy Study

    2020  

    Abstract: Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a ... ...

    Abstract Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis. Methods: The Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic. Results: Of 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X-ray plus molecular testing (PCR) being the commonest (19·8 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6·6 and 2·4 per cent respectively before, but 23·7 and 5·3 per cent, during the pandemic (both P < 0·001). One-third changed their approach from laparoscopic to open surgery owing to the popular (but evidence-lacking) advice from expert groups during the initial phase of the pandemic. No agreement on how to filter surgical smoke plume during laparoscopy was identified. There was an overall reduction in the number of patients admitted with appendicitis and one-third felt that patients who did present had more severe appendicitis than they usually observe. Conclusion: Conservative management of mild appendicitis has been possible during the pandemic. The fact that some surgeons switched to open appendicectomy may reflect the poor guidelines that emanated in the early phase of SARS-CoV-2.
    Keywords covid19
    Subject code 610
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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