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  1. Article ; Online: Impaired cardiorespiratory fitness and endothelial function after SARS-CoV-2 infection in a sample of mainly immunocompromised youth.

    Astley, Camilla / Prado, Danilo Marcelo Leite do / Sieczkowska, Sofia Mendes / Esteves, Gabriel P / Suguita, Priscila / Fink, Thais / Lindoso, Livia / Matsuo, Olivia / Martins, Fernanda / Bain, Vera / Badue Pereira, Maria Fernanda / Marques, Heloisa Helena / Malluf, Adriana / Leal, Gabriela Nunes / Silva, Clovis Artur / Roschel, Hamilton / Gualano, Bruno

    Journal of applied physiology (Bethesda, Md. : 1985)

    2023  Volume 135, Issue 6, Page(s) 1323–1329

    Abstract: This study aimed to compare cardiopulmonary fitness and endothelial function 6 months after hospital diagnosis in a sample mainly comprising immunocompromised patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection ... ...

    Abstract This study aimed to compare cardiopulmonary fitness and endothelial function 6 months after hospital diagnosis in a sample mainly comprising immunocompromised patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection versus noninfected controls. Youth (
    MeSH term(s) Female ; Child ; Humans ; Adolescent ; Male ; COVID-19 ; SARS-CoV-2 ; Cardiorespiratory Fitness ; Post-Acute COVID-19 Syndrome ; Brazil/epidemiology
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00213.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Staphylococcus aureus colonization in Brazilian children.

    Mimica, Marcelo J / Bádue-Pereira, Maria Fernanda

    Germs

    2014  Volume 4, Issue 1, Page(s) 22

    Language English
    Publishing date 2014-03-03
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2649305-6
    ISSN 2248-2997
    ISSN 2248-2997
    DOI 10.11599/germs.2014.1051
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  3. Article ; Online: Panton-Valentine Positive Staphylococcus aureus in Community-Acquired and Hospital-Acquired Pediatric Infections.

    Bádue Pereira, Maria Fernanda / Bando, Silvia Yumi / Sasagawa, Suzethe Matiko / da Silva, Cely Barreto / Mimica, Marcelo Jenne / Berezin, Eitan Naaman

    The Pediatric infectious disease journal

    2019  Volume 38, Issue 10, Page(s) 1068–1070

    Abstract: From July 2009 to July 2015, Staphylococcus aureus isolated from pediatric sterile sites were selected. Polymerase chain reaction was used to detect mecA and lukS-PV/lukF-PV genes. The rate of methicillin-resistant Staphylococcus aureus was 37.7%. Ten ... ...

    Abstract From July 2009 to July 2015, Staphylococcus aureus isolated from pediatric sterile sites were selected. Polymerase chain reaction was used to detect mecA and lukS-PV/lukF-PV genes. The rate of methicillin-resistant Staphylococcus aureus was 37.7%. Ten isolates had the lukS-PV/lukF-PV genes, 2 of which were methicillin-resistant Staphylococcus aureus. Skin and soft tissues infections were significantly associated with lukS-PV/lukF-PV positive isolates, P = 0.008.
    MeSH term(s) Adolescent ; Bacterial Proteins/genetics ; Bacterial Toxins/genetics ; Child ; Child, Preschool ; Community-Acquired Infections/microbiology ; Cross Infection/microbiology ; Exotoxins/genetics ; Female ; Humans ; Infant ; Leukocidins/genetics ; Male ; Polymerase Chain Reaction ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/enzymology ; Staphylococcus aureus/genetics ; Staphylococcus aureus/isolation & purification
    Chemical Substances Bacterial Proteins ; Bacterial Toxins ; Exotoxins ; Leukocidins ; Panton-Valentine leukocidin ; leukocidin S-component protein, Staphylococcus ; LukF protein, Staphylococcus aureus (147096-70-6)
    Language English
    Publishing date 2019-09-25
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mental health among children and adolescents after SARS-CoV-2 infection: A prospective study in a tertiary university hospital.

    Matsuo, Olivia Mari / Lindoso, Livia / Sousa Marques, Heloisa Helena de / Polanczyk, Guilherme V / Farhat, Sylvia Costa Lima / Bain, Vera / Fink, Thais T / Martins, Fernanda / Astley, Camilla / Suguita, Priscila / Trindade, Vitor / Correa-Silva, Simone / Palmeira, Patricia / Yoshino de Paula, Camila Sanson / Litvinov, Nadia / Ferreira, Juliana Caires O A / Sakita, Neusa Keico / Gualano, Bruno / Silva, Clovis Artur A /
    Pereira, Maria Fernanda Badue

    The Journal of infection

    2023  Volume 87, Issue 6, Page(s) 576–578

    MeSH term(s) Adolescent ; Child ; Humans ; Prospective Studies ; Mental Health ; COVID-19 ; SARS-CoV-2 ; Hospitals, University
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Letter
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2023.09.005
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  5. Article ; Online: In-depth cardiovascular and pulmonary assessments in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: A case series study.

    Astley, Camilla / Badue Pereira, Maria Fernanda / Lima, Marcos Santos / Buchpiguel, Carlos Alberto / Carneiro, Camila G / Sapienza, Marcelo Tatit / Leal, Gabriela Nunes / do Prado, Danilo Marcelo Leite / Peçanha, Tiago / Sieczkowska, Sofia Mendes / Matsuo, Olivia Mari / Lindoso, Livia / Marques, Heloisa Helena / Silva, Clovis Artur / Gualano, Bruno

    Physiological reports

    2022  Volume 10, Issue 5, Page(s) e15201

    Abstract: We assessed PET-CT myocardial blood flow (MBF) using N-13 ammonia, brachial flow-mediated dilation, and cardiopulmonary exercise test in five post-discarged MIS-C survivors. None of the patients (median age: 9, range: 7-18 years; 3 females; 2 males) had ... ...

    Abstract We assessed PET-CT myocardial blood flow (MBF) using N-13 ammonia, brachial flow-mediated dilation, and cardiopulmonary exercise test in five post-discarged MIS-C survivors. None of the patients (median age: 9, range: 7-18 years; 3 females; 2 males) had preexisting pediatric chronic conditions. At the follow-up visit, two patients exhibited severe perfusion defect developed in the left ventricular cavity, suggesting extensive myocardial ischemia (MBF <2.0) and one patient showed persistent mild pericardial effusion. Others two patients demonstrated endothelial dysfunction. Nevertheless, all patients had lower predicted values in the VO
    MeSH term(s) COVID-19/complications ; Cardiovascular System ; Child ; Female ; Humans ; Male ; Positron Emission Tomography Computed Tomography ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
    Language English
    Publishing date 2022-03-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.15201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Home-Based Exercise Training in the Recovery of Multisystem Inflammatory Syndrome in Children: A Case Series Study.

    Astley, Camilla / Leal, Gabriela Nunes / Gil, Saulo / Suguita, Priscila / Fink, Thais / Bain, Vera / Pereira, Maria Fernanda Badue / Marques, Heloisa Helena / Sieczkowska, Sofia / Prado, Danilo / Lima, Marcos Santos / Carneiro, Camila G / Buchpiguel, Carlos Alberto / Silva, Clovis Artur / Gualano, Bruno

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 5

    Abstract: Objective: To assess the potential therapeutic role of exercise on health-related quality of life, assessed by the Pediatric Outcomes Data Collection Instrument (PODCI), coronary flow reserve (CFR), cardiac function, cardiorespiratory fitness, and ... ...

    Abstract Objective: To assess the potential therapeutic role of exercise on health-related quality of life, assessed by the Pediatric Outcomes Data Collection Instrument (PODCI), coronary flow reserve (CFR), cardiac function, cardiorespiratory fitness, and inflammatory and cardiac blood markers in multisystemic inflammatory syndrome in children (MIS-C) patients.
    Methods: This is a case series study of a 12-wk, home-based exercise intervention in children and adolescents after MIS-C diagnosis. From 16 MIS-C patients followed at our clinic, 6 were included (age: 7-16 years; 3 females). Three of them withdrew before the intervention and served as controls. The primary outcome was health-related quality of life, assessed PODCI. Secondary outcomes were CFR assessed by 13N-ammonia PET-CT imaging, cardiac function by echocardiography, cardiorespiratory fitness, and inflammatory and cardiac blood markers.
    Results: In general, patients showed poor health-related quality of life, which seemed to be improved with exercise. Additionally, exercised patients showed improvements in coronary flow reserve, cardiac function, and aerobic conditioning. Non-exercised patients exhibited a slower pattern of recovery, particularly in relation to health-related quality of life and aerobic conditioning.
    Conclusions: Our results suggest that exercise may play a therapeutic role in the treatment of post-discharge MIS-C patients. As our design does not allow inferring causality, randomized controlled trials are necessary to confirm these preliminary findings.
    Language English
    Publishing date 2023-05-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10050889
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  7. Article ; Online: Breakthrough Candidemia in Pediatric Patients With Cancer From a Brazilian Center.

    Barrientos, Anna Carlota Mott / Nobrega de Almeida Junior, João / Litvinov, Nadia / Bain, Vera / Cristofani, Lilian Maria / Badue Pereira, Maria Fernanda / Sanson Yoshino de Paula, Camila / Lopes Motta, Adriana / Rossi, Flavia / Bárbaro Del Negro, Gilda Maria / Yamamoto Thomaz, Danilo / Sousa Marques, Heloisa Helena

    The Pediatric infectious disease journal

    2021  Volume 40, Issue 3, Page(s) 251–254

    Abstract: We analyzed 19 cases of breakthrough candidemia from a referral pediatric cancer center in Brazil. All patients had neutropenia and were under antifungal prophylactic regimens, mostly micafungin (68%). Most of the patients were treated with amphotericin ... ...

    Abstract We analyzed 19 cases of breakthrough candidemia from a referral pediatric cancer center in Brazil. All patients had neutropenia and were under antifungal prophylactic regimens, mostly micafungin (68%). Most of the patients were treated with amphotericin B formulations and 30-day mortality was 21%. Candida parapsilosis was the main etiologic agent (63%), and horizontal transmission was not evidenced by microsatellite analysis.
    MeSH term(s) Antifungal Agents/therapeutic use ; Brazil ; Candida/classification ; Candidemia/complications ; Catheter-Related Infections/drug therapy ; Catheter-Related Infections/microbiology ; Child ; Humans ; Neoplasms/complications ; Retrospective Studies
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High Fatality Rates in Pediatric Multisystem Inflammatory Syndrome: A Multicenter Experience From the Epicenter of Brazil's Coronavirus Pandemic.

    Almeida, Flávia Jacqueline / Jarovsky, Daniel / Almeida Farias, Camila Giuliana / Ramos Nantes de Castilho, Taisa Roberta / Gara Caetano, Thiago / Manzoni Ribeiro Borsetto, Cibele Cristina / Simões Aguiar, Andressa / Serafini de Araújo, Carolina / Badue Pereira, Maria Fernanda / de Sousa Marques, Heloisa Helena / Silva, Clovis Artur / Ribeiro de Matos Tannure, Andressa / Prado, Rogério / Becker Mau, Luciana / Andrade Alvares, Paula / de Siqueira, Antônio Carlos / Paro Scremin, Gustavo / Otsuka, Marcelo / Volpe Arnoni, Mariana /
    Machado Rissoni Laporte, Roberta / Altruda de Moraes Costa Carlesse, Fabianne / Ejzenberg, Fernanda / Naaman Berezin, Eitan / Palazzi Sáfadi, Marco Aurélio

    The Pediatric infectious disease journal

    2023  

    Abstract: Background: Brazil´s case fatality rate (CFR) of pediatric multisystem inflammatory syndrome in children and adolescents (MIS-C) is among the highest worldwide. Despite these concerns, limited hospital-based and comprehensive pediatric data have been ... ...

    Abstract Background: Brazil´s case fatality rate (CFR) of pediatric multisystem inflammatory syndrome in children and adolescents (MIS-C) is among the highest worldwide. Despite these concerns, limited hospital-based and comprehensive pediatric data have been published on MIS-C in Brazilian children.
    Methods: We performed a descriptive analysis of the MIS-C scores in 16 public and private hospitals providing secondary and tertiary care in the metropolitan area of São Paulo, Brazil. Clinical and demographic information were systematically extracted from the electronic medical records of each patient. Logistic regression analysis was performed to identify the combined effects of MIS-C phenotype, disease severity and comorbidity as dependent variables.
    Results: A total of 101 patients met the MIS-C criteria and were evaluated. The median age was 67 months, 60% were male, 28.7% were black or afrodescendant and 62.3% were admitted to public hospitals. Underlying medical conditions were observed in 16.8% of patients and were associated with a longer duration of hospitalization. A Kawasaki disease-like phenotype was observed in 43.5% of patients, and they demonstrated a trend of lower median age. Children with severe MIS-C were older (median age 91 months vs. 36 months) and had a nonspecific phenotype, more cardiovascular and respiratory involvement and kidney injury; 73.3% required intensive care, 20.8% required mechanical ventilation and 35.6% required inotropic support. Four deaths occurred (CFR = 3.9%), three of which were in healthy participants.
    Conclusion: We identified a lower median age, particularly among children with Kawasaki disease-like phenotypes, those with a significant need for intensive care, and a high CFR in MIS-C. Our findings confirmed the increased severity of the disease in the selected Brazilian population.
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000004164
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  9. Article ; Online: Shanghai Fever in a Healthy Infant: First Report in South America.

    Penteado, Fernando Domingues / Bain, Vera / Durigon, Giuliana Stravinskas / Litvinov, Nadia / Pereira, Maria Fernanda Badue / de Sousa Marques, Heloisa Helena

    The Pediatric infectious disease journal

    2018  Volume 37, Issue 11, Page(s) e278–e279

    MeSH term(s) Child ; China ; Diarrhea ; Fever ; Humans ; Infant ; Pseudomonas aeruginosa ; South America
    Language English
    Publishing date 2018-10-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002005
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  10. Article ; Online: Mycobacterial Disease in Immunocompromised Children in a High Endemic Area.

    Schuwartz, Constance Dell' Santo Vieira / Galastri, Anne Layze / Durigon, Giuliana Stravinskas / Litvinov, Nadia / Pereira, Maria Fernanda Badue / Marques, Heloisa Helena de Sousa

    The Pediatric infectious disease journal

    2018  Volume 37, Issue 1, Page(s) 111

    MeSH term(s) Child ; Humans ; Immunocompromised Host ; Prevalence ; Risk Factors ; Tuberculosis/epidemiology
    Language English
    Publishing date 2018-01-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000001692
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